--- title: "Islip to Santo Domingo cheap flights from $240 (ISP to SDQ) - Expedia" description: "Cheap Flights from Islip (ISP) to Santo Domingo (SDQ) start at $240 for one-way and $672 for round trip. Earn your airline miles on top of our rewards!" canonical: "https://www.expedia.com/lp/flights/isp/sdq/islip-to-santo-domingo" language: en-US market: US currency: USD prices_as_of: 2026-11-12T22:00:20Z --- # $240 Cheap Flights from Islip (ISP) to Santo Domingo (SDQ) ![A historic plaza with a fountain, trees, and a building with arches.](https://images.trvl-media.com/place/5325907/12485767-44cd-4565-9628-c28cdc4e08f1.jpg?impolicy=fcrop&w=1200&h=500&q=medium) [View $240 flight on Sun, Jan 10, 2027](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:1/10/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:239.91&airProductToken=AQpgCi4IxnISBDIxNDkYyHwgzHAoypiiAzCEmqIDOEVAAFgBagRQQ18xcgdHMjFQTUM0Ci4IxnISAzI4OBjMcCDygAEosp6iAzDRn6IDOEVAAVgBagRQQ18xcgdHMjFQTUM0EgoIARABGAEqAkY5GAEiBAgBEAEoAigDKAQwDQ) ## Popular airlines from MacArthur Airport (ISP) to Las Americas Intl. Airport (SDQ) [JetBlue Airways](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:11/26/2026TANYT&leg2=from:SDQ,to:ISP,departure:12/3/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"B6"}}]) ### Be in the know Get alerts if flight prices drop or rise\* ### Book smarter Save up to 30% on select hotels after you book a flight\* ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## Cheap Flights from Islip to Santo Domingo (ISP-SDQ) Prices were available within the past 7 days and start at $240 for one-way flights and $672 for roundtrip, for the period specified. Prices and availability are subject to change. All deals One way Roundtrip [Select JetBlue Airways flight, departing Sun, Nov 22 from Islip to Santo Domingo, returning Thu, Nov 26, priced at $672 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:11/22/2026TANYT&leg2=from:SDQ,to:ISP,departure:11/26/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:671.93&airProductToken=AQpeCiwIwmwSAzU0NxjIfCDMcCig7Z0DMM%5FunQM4TEAAWAFqAkROcghVQzRBUkVZMQouCMJsEgQxMTA1GMxwIPKAASiL8p0DMKfznQM4TEABWAFqAkROcghVQzRBUkVZMQpeCi4IwmwSBDI0NDgY8oABIOVaKPiangMwipyeAzhMQABYAWoCRE5yCFVDNEFSRVkxCiwIwmwSAzUxNBjlWiDIfCjNnZ4DMPyengM4TEABWAFqAkROcghVQzRBUkVZMRIKCAEQARgBKgJCNhgBIgQIARABKAIoAygEMAE) Sun, Nov 22 - Thu, Nov 26 · ISP · SDQ · Roundtrip [Select Frontier Airlines flight, departing Fri, Feb 26 from Islip to Santo Domingo, returning Sat, Mar 6, priced at $737 Found 6 days ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:2/26/2027TANYT&leg2=from:SDQ,to:ISP,departure:3/6/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:736.35&airProductToken=AQpeCi0IxnISBDM5NDEYyHwgzHAo-6SmAzC2pqYDOE1AAFgBagNFQ09yB00yMVBNQzIKLQjGchIDMjg4GMxwIPKAASjAr6YDMOOwpgM4TUABWAFqA0VDT3IHTTIxUE1DMhIKCAEQARgBKgJGORgBIgQIARABKAIoAygEMAE) Fri, Feb 26 - Sat, Mar 6 · ISP · SDQ · Roundtrip [Select JetBlue Airways flight, departing Fri, Mar 5 from Islip to Santo Domingo, returning Wed, Mar 10, priced at $737 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:3/5/2027TANYT&leg2=from:SDQ,to:ISP,departure:3/10/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:736.93&airProductToken=AQpeCiwIwmwSAzU0NxjIfCDMcCjb9KYDMJD2pgM4TEAAWAFqAkROcghPQzJBUkVZMQouCMJsEgQxNDA1GMxwIPKAASjc-6YDMPD8pgM4TEABWAFqAkROcghPQzJBUkVZMQpeCi4IwmwSBDI0NDgY8oABIOVaKPKspwMwha6nAzhMQABYAWoCRE5yCFVDMkFSRVkxCiwIwmwSAzMxNBjlWiDIfCiqr6cDMNewpwM4TEABWAFqAkROcghVQzJBUkVZMRIMCAEQARgBKgJCNjIAGAEiBAgBEAEoAigDKAQwAQ) Fri, Mar 5 - Wed, Mar 10 · ISP · SDQ · Roundtrip [Select JetBlue Airways flight, departing Fri, Mar 5 from Islip to Santo Domingo, returning Wed, Mar 10, priced at $752 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:3/5/2027TANYT&leg2=from:SDQ,to:ISP,departure:3/10/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:751.97&airProductToken=AQpeCiwIwmwSAzU0NxjIfCDMcCjb9KYDMJD2pgM4TEAAWAFqAkROcghPQzJBUkVZMQouCMJsEgQxNDA1GMxwIPKAASjc-6YDMPD8pgM4TEABWAFqAkROcghPQzJBUkVZMQpdCi0IwmwSAzU5MBjygAEg5Voo662nAzD-rqcDOExAAFgBagJETnIIVUMyQVJFWTEKLAjCbBIDNTE0GOVaIMh8KLq4pwMw5bmnAzhMQAFYAWoCRE5yCFVDMkFSRVkxEgwIARABGAEqAkI2MgAYASIECAEQASgCKAMoBDAB) Fri, Mar 5 - Wed, Mar 10 · ISP · SDQ · Roundtrip [Select JetBlue Airways flight, departing Fri, Mar 5 from Islip to Santo Domingo, returning Wed, Mar 10, priced at $755 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:3/5/2027TANYT&leg2=from:SDQ,to:ISP,departure:3/10/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:754.71&airProductToken=AQpeCiwIwmwSAzMxMxjIfCDlWijY9qYDMJf4pgM4TEAAWAFqAkROcghPQzJBUkVZMQouCMJsEgQyNTQ5GOVaIPKAASiT%5FqYDMJ3%5FpgM4TEABWAFqAkROcghPQzJBUkVZMQpeCi4IwmwSBDEyNDgY8oABIOVaKNmopwMw6qmnAzhMQABYAWoCRE5yCFVDMkFSRVkxCiwIwmwSAzUxNBjlWiDIfCiaracDMMWupwM4TEABWAFqAkROcghVQzJBUkVZMRIMCAEQARgBKgJCNjIAGAEiBAgBEAEoAigDKAQwAQ) Fri, Mar 5 - Wed, Mar 10 · ISP · SDQ · Roundtrip [Select Frontier Airlines flight, departing Fri, Mar 5 from Islip to Santo Domingo, returning Wed, Mar 10, priced at $758 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:3/5/2027TANYT&leg2=from:SDQ,to:ISP,departure:3/10/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:757.08&airProductToken=AQpeCi0IxnISBDM5NDEYyHwgzHAo2%5FOmAzCW9aYDOE1AAFgBagNFQ09yB00yMVBNQzUKLQjGchIDMjg4GMxwIPKAASig%5FqYDMMP%5FpgM4TUABWAFqA0VDT3IHTTIxUE1DNRIMCAEQARgBKgJGOTIAGAEiBAgBEAEoAigDKAQwAQ) Fri, Mar 5 - Wed, Mar 10 · ISP · SDQ · Roundtrip [Select Frontier Airlines flight, departing Sun, Jan 10 from Islip to Santo Domingo, returning Wed, Jan 20, priced at $763 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:1/10/2027TANYT&leg2=from:SDQ,to:ISP,departure:1/20/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:762.03&airProductToken=AQpgCi4IxnISBDIxNDkYyHwgzHAoypiiAzCEmqIDOEVAAFgBagRQQ18xcgdHMjFQTUM0Ci4IxnISAzI4OBjMcCDygAEosp6iAzDRn6IDOEVAAVgBagRQQ18xcgdHMjFQTUM0EgoIARABGAEqAkY5GAEiBAgBEAEoAigDKAQwDQ) Sun, Jan 10 - Wed, Jan 20 · ISP · SDQ · Roundtrip [Select JetBlue Airways flight, departing Fri, Mar 5 from Islip to Santo Domingo, returning Wed, Mar 10, priced at $770 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:3/5/2027TANYT&leg2=from:SDQ,to:ISP,departure:3/10/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:769.75&airProductToken=AQpeCiwIwmwSAzMxMxjIfCDlWijY9qYDMJf4pgM4TEAAWAFqAkROcghPQzJBUkVZMQouCMJsEgQyNTQ5GOVaIPKAASiT%5FqYDMJ3%5FpgM4TEABWAFqAkROcghPQzJBUkVZMQpdCi0IwmwSAzU5MBjygAEg5Voo662nAzD-rqcDOExAAFgBagJETnIIVUMyQVJFWTEKLAjCbBIDNTE0GOVaIMh8KLq4pwMw5bmnAzhMQAFYAWoCRE5yCFVDMkFSRVkxEgwIARABGAEqAkI2MgAYASIECAEQASgCKAMoBDAB) Fri, Mar 5 - Wed, Mar 10 · ISP · SDQ · Roundtrip [Select JetBlue Airways flight, departing Sun, Feb 28 from Islip to Santo Domingo, returning Wed, Mar 3, priced at $772 Found 6 days ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:2/28/2027TANYT&leg2=from:SDQ,to:ISP,departure:3/3/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:771.93&airProductToken=AQpeCiwIwmwSAzUxMxjIfCDlWijPuKYDMI26pgM4VUAAWAFqAkFOcghVQzJBUkVZNQouCMJsEgQyNTQ5GOVaIPKAASjTuqYDMN27pgM4VUABWAFqAkFOcghVQzJBUkVZNQpeCi4IwmwSBDI0NDgY8oABIOVaKJLepgMwpd-mAzhVQABYAWoCQU5yCFVDMkFSRVk1CiwIwmwSAzMxNBjlWiDIfCjK4KYDMPfhpgM4VUABWAFqAkFOcghVQzJBUkVZNRIMCAEQARgBKgJCNjIAGAEiBAgBEAEoAigDKAQwAQ) Sun, Feb 28 - Wed, Mar 3 · ISP · SDQ · Roundtrip [Select JetBlue Airways flight, departing Thu, Jan 28 from Islip to Santo Domingo, returning Sun, Jan 31, priced at $778 Found 6 days ago](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:1/28/2027TANYT&leg2=from:SDQ,to:ISP,departure:1/31/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:777.85&airProductToken=AQpeCiwIwmwSAzUxMxjIfCDlWij026MDMLHdowM4TEAAWAFqAkROcghPQzRBVUVZMQouCMJsEgQxODA5GOVaIPKAASiY36MDMKPgowM4TEABWAFqAkROcghPQzRBVUVZMRIKCAEQARgBKgJCNhgBIgQIARABKAIoAygEMAE) Thu, Jan 28 - Sun, Jan 31 · ISP · SDQ · Roundtrip ## Alternative airports near Santo Domingo Prices were available within the past 7 days. Prices and availability are subject to change. [Select flight to Las Americas Intl. SDQ. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $852](https://www.expedia.com/Flights-Search?leg1=from:ISP,to:SDQ,departure:11/26/2026TANYT&leg2=from:SDQ,to:ISP,departure:12/9/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) 22 min ## Book with confidence ### Islip to Santo Domingo Flights #### The cheapest times to fly from Islip to Santo Domingo On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Islip to Santo Domingo are during the month of November. You can find some of the cheapest flights from Islip to Santo Domingo with Expedia's search tool and vast selection of airlines. #### The best time to book a flight from Islip to Santo Domingo Sunday is one of the best days to book for cheap flights from Islip to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. #### How to find cheap round-trip tickets from Islip to Santo Domingo Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Islip to Santo Domingo in 2026\. You can also book with separate airlines for your outbound and return journeys, from $240 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Islip to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Islip to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. *\*Terms apply.* *Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages.* ## Frequently Asked Questions ### How much does a flight from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) cost? You can find cheap one-way flights from $240 and cheap return flights $672 Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) with Expedia. Return flights typically cost between $940 and $5108\. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) ticket fares go up or down. *\*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.* ### What is the cheapest month to fly from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? The cheapest month to fly from ISP to SDQ is November when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route. ### Which airlines fly direct from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? Enter ISP to SDQ and your travel dates, then apply the 'Nonstop' filter to see only direct flights. ### What is the cheapest airline that flies from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? Frontier Airlines is one of the cheapest airlines offering connecting flights from MacArthur (ISP) to Las Americas Intl. (SDQ), with round-trip tickets starting from around $837\. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget. *\*Prices based on flights available on Expedia in the last year.* ### How do I find cheap flights from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? To find a cheap flight from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up [Price Tracking](https://www.expedia.com/why/price-tracking) and receive alerts when fares go up or down. ### What is the best time to fly from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience. ### What is the earliest flight from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? The earliest flight from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) typically departs at around 7:30 AM, operated by 9K and United Airlines. This is a seasonal service active in December, making it a great option for winter getaways. An early departure like this allows you to make the most of your time in Santo Domingo. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search. ### What day of the week has the most flights from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? You'll usually find the most flights from MacArthur (ISP) to Las Americas Intl. (SDQ) on a Friday, with around 7 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include JetBlue Airways and Frontier Airlines. ### What are the most popular departure times for flights from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? The most popular departure times for flights from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) are in the late morning, from 9am to noon. About 64% of passengers prefer this time window. Many major carriers, including JetBlue Airways, offer flights during this window. This timing works well because it allows you to start your day early and arrive in Santo Domingo with plenty of time to enjoy the afternoon. ### How long does it take to fly from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? Flying from ISP to SDQ with a connection usually takes about 7 hours 20 minutes, traveling roughly 1,558 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic. ### Can you fly business or first class from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? Select the "Business class" and "First class" filters when looking for ISP to SDQ flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip. ### How do I earn miles on a Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) flight with Expedia? It's easy to earn miles on a Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of [One Key™](https://www.expedia.com/welcome-one-key), you can also earn OneKeyCash™\* on top of your airline miles when you book with Expedia. \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands. ### What airports do you fly into for Santo Domingo from MacArthur (ISP)? From MacArthur (ISP), you can fly into Las Americas Intl. (SDQ) to reach Santo Domingo. Some flights may connect through major hubs like Logan Intl. (BOS) before reaching Santo Domingo. Compare routes and airports on Expedia to find the best flight options for your travel plans. ### Is it cheaper to buy a plane ticket from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) at the last minute? Typically, booking a last minute flight from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare. ### Is it cheaper to book a Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) flight and hotel package? Securing a Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) [Santo Domingo Vacation Packages](https://www.expedia.com/santo-domingo.d180024.destination-travel-guides) is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars. ### Can I cancel or change the date of my flight from Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.)? If you booked your Islip, NY (ISP-MacArthur) to Santo Domingo (SDQ-Las Americas Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in [your itinerary](https://www.expedia.com/trips) or confirmation email. Or, head to our [Customer Service portal](https://www.expedia.com/helpcenter/) if you'd like more information. ## Travel information | Origin airport | MacArthur Airport | | ------------------- | -------------------------- | | Destination airport | Las Americas Intl. Airport | | Distance | 1,557 miles away | | Airlines serving | JetBlue Airways | | Popular airline | JetBlue Airways | | Roundtrip price | $672 | ## Explore a world of travel with Expedia - [Flights](?equalTargetTab=tab-0) - [Flights from Managua (MGA) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/mga/sdq/managua-to-santo-domingo) - [Flights from Santiago (SCL) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/scl/sdq/santiago-to-santo-domingo) - [Flights from Austin (AUS) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/aus/sdq/austin-to-santo-domingo) - [Flights from Las Vegas (LAS) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/las/sdq/las-vegas-to-santo-domingo) - [Flights from Georgetown (GEO) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/geo/sdq/georgetown-to-santo-domingo) - [Flights from Seattle (SEA) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/sea/sdq/seattle-to-santo-domingo) - [Flights from Houston (HOU) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/hou/sdq/houston-to-santo-domingo) - [Flights from Lagos (LOS) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/los/sdq/lagos-to-santo-domingo) - [Flights from Barcelona (BCN) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/bcn/sdq/barcelona-to-santo-domingo) - [Flights from Salt Lake City (SLC) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/slc/sdq/salt-lake-city-to-santo-domingo) - [Flights from Syracuse (SYR) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/syr/sdq/syracuse-to-santo-domingo) - [Flights from Atlanta (ATL) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/atl/sdq/atlanta-to-santo-domingo) - [Flights from Indianapolis (IND) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/ind/sdq/indianapolis-to-santo-domingo) - [Flights from Cartagena (CTG) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/ctg/sdq/cartagena-to-santo-domingo) - [Flights from Los Angeles (LAX) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/lax/sdq/los-angeles-to-santo-domingo) - [Flights from Philipsburg (SXM) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/sxm/sdq/philipsburg-to-santo-domingo) - [Flights from Columbus (CMH) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/cmh/sdq/columbus-to-santo-domingo) - [Flights from St. John's (ANU) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/anu/sdq/st-johns-to-santo-domingo) - [Flights from Bridgetown (BGI) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/bgi/sdq/bridgetown-to-santo-domingo) - [Flights from Richmond (RIC) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/ric/sdq/richmond-to-santo-domingo) - [Flights from Quito (UIO) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/uio/sdq/quito-to-santo-domingo) - [Flights from Cleveland (CLE) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/cle/sdq/cleveland-to-santo-domingo) - [Flights from Jacksonville (JAX) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/jax/sdq/jacksonville-to-santo-domingo) - [Flights from Portland (PDX) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/pdx/sdq/portland-to-santo-domingo) - [Flights from Orlando (MCO) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/mco/sdq/orlando-to-santo-domingo) - [Flights from Grand Rapids (GRR) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/grr/sdq/grand-rapids-to-santo-domingo) - [Flights from Bonaire (BON) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/bon/sdq/bonaire-to-santo-domingo) - [Flights from Toronto (YYZ) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/yyz/sdq/toronto-to-santo-domingo) - [Flights from Cali (CLO) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/clo/sdq/cali-to-santo-domingo) - [Flights from Providenciales (PLS) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/pls/sdq/providenciales-to-santo-domingo) - [Flights from Mexico City (MEX) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/mex/sdq/mexico-city-to-santo-domingo) - [Flights from San Juan (SJU) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/sju/sdq/san-juan-to-santo-domingo) - [Flights from Nassau (NAS) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/nas/sdq/nassau-to-santo-domingo) - [Flights from Baltimore (BWI) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/bwi/sdq/baltimore-to-santo-domingo) - [Flights from Cincinnati (CVG) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/cvg/sdq/cincinnati-to-santo-domingo) - [Flights from San Pedro Sula (SAP) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/sap/sdq/san-pedro-sula-to-santo-domingo) - [Flights from San Diego (SAN) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/san/sdq/san-diego-to-santo-domingo) - [Flights from San Francisco (SFO) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/sfo/sdq/san-francisco-to-santo-domingo) - [Flights from San Salvador (SAL) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/sal/sdq/san-salvador-to-santo-domingo) - [Flights from Puerto Plata (POP) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/pop/sdq/puerto-plata-to-santo-domingo) - [Flights from Phoenix (PHX) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/phx/sdq/phoenix-to-santo-domingo) - [Flights from New York (LGA) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/lga/sdq/new-york-to-santo-domingo) - [Flights from Belize City (BZE) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/bze/sdq/belize-city-to-santo-domingo) - [Flights from Dallas (DFW) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/dfw/sdq/dallas-to-santo-domingo) - [Flights from Hartford (BDL) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/bdl/sdq/hartford-to-santo-domingo) - [Flights from Houston (IAH) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/iah/sdq/houston-to-santo-domingo) - [Flights from Tampa (TPA) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/tpa/sdq/tampa-to-santo-domingo) - [Flights from Cancun (CUN) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/cun/sdq/cancun-to-santo-domingo) - [Flights from Buffalo (BUF) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/buf/sdq/buffalo-to-santo-domingo) - [Flights from Pittsburgh (PIT) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/pit/sdq/pittsburgh-to-santo-domingo) - [Flights from Providence (PVD) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/pvd/sdq/providence-to-santo-domingo) - [Flights from Fort Lauderdale (FLL) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/fll/sdq/fort-lauderdale-to-santo-domingo) - [Flights from Aguadilla (BQN) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/bqn/sdq/aguadilla-to-santo-domingo) - [Flights from Tortola (EIS) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/eis/sdq/tortola-to-santo-domingo) - [Flights from New Orleans (MSY) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/msy/sdq/new-orleans-to-santo-domingo) - [Flights from Minneapolis (MSP) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/msp/sdq/minneapolis-to-santo-domingo) - [Flights from Cap-Haitien (CAP) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/cap/sdq/cap-haitien-to-santo-domingo) - [Flights from Kansas City (MCI) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/mci/sdq/kansas-city-to-santo-domingo) - [Flights from San José (SJO) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/sjo/sdq/san-jose-to-santo-domingo) - [Flights from St. Thomas (STT) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/stt/sdq/st-thomas-to-santo-domingo) - [Flights from Montreal (YUL) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/yul/sdq/montreal-to-santo-domingo) - [Flights from Basseterre (SKB) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/skb/sdq/basseterre-to-santo-domingo) - [Flights from Lima (LIM) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/lim/sdq/lima-to-santo-domingo) - [Flights from Norfolk (ORF) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/orf/sdq/norfolk-to-santo-domingo) - [Flights from Nashville (BNA) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/bna/sdq/nashville-to-santo-domingo) - [Flights from New York (JFK) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/jfk/sdq/new-york-to-santo-domingo) - [Flights from Panama City (PTY) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/pty/sdq/panama-city-to-santo-domingo) - [Flights from Charlotte (CLT) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/clt/sdq/charlotte-to-santo-domingo) - [Flights from Fresno (FAT) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/fat/sdq/fresno-to-santo-domingo) - [Flights from Detroit (DTW) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/dtw/sdq/detroit-to-santo-domingo) - [Flights from Kingston (KIN) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/kin/sdq/kingston-to-santo-domingo) - [Flights from San Antonio (SAT) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/sat/sdq/san-antonio-to-santo-domingo) - [Flights from Oranjestad (AUA) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/aua/sdq/oranjestad-to-santo-domingo) - [Flights from Bogotá (BOG) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/bog/sdq/bogota-to-santo-domingo) - [Flights from Newark Liberty Intl. Airport (EWR) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/ewr/sdq/newark-liberty-intl-airport-to-santo-domingo) - [Flights from Buenos Aires (EZE) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/eze/sdq/buenos-aires-to-santo-domingo) - [Flights from Boston (BOS) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/bos/sdq/boston-to-santo-domingo) - [Flights from Charleston (CHS) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/chs/sdq/charleston-to-santo-domingo) - [Flights from Rochester (ROC) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/roc/sdq/rochester-to-santo-domingo) - [Flights from Santiago (STI) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/sti/sdq/santiago-to-santo-domingo) - [Flights from Willemstad (CUR) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/cur/sdq/willemstad-to-santo-domingo) - [Flights from Montego Bay (MBJ) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/mbj/sdq/montego-bay-to-santo-domingo) - [Flights from Harrisburg (MDT) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/mdt/sdq/harrisburg-to-santo-domingo) - [Flights from Medellín (MDE) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/mde/sdq/medellin-to-santo-domingo) - [Flights from Guayaquil (GYE) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/gye/sdq/guayaquil-to-santo-domingo) - [Flights from Christiansted (STX) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/stx/sdq/christiansted-to-santo-domingo) - [Flights from Paramaribo (PBM) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/pbm/sdq/paramaribo-to-santo-domingo) - [Flights from Punta Cana (PUJ) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/puj/sdq/punta-cana-to-santo-domingo) - [Flights from Washington (IAD) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/iad/sdq/washington-to-santo-domingo) - [Flights from Guatemala City (GUA) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/gua/sdq/guatemala-city-to-santo-domingo) - [Flights from Madrid (MAD) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/mad/sdq/madrid-to-santo-domingo) - [Flights from Denver (DEN) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/den/sdq/denver-to-santo-domingo) - [Flights from Miami (MIA) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/mia/sdq/miami-to-santo-domingo) - [Flights from Chicago (ORD) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/ord/sdq/chicago-to-santo-domingo) - [Flights from Philadelphia (PHL) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/phl/sdq/philadelphia-to-santo-domingo) - [Flights from New York (NYC) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/nyc/sdq/new-york-to-santo-domingo) - [Flights from Port of Spain (POS) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/pos/sdq/port-of-spain-to-santo-domingo) - [Flights from Washington (DCA) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/dca/sdq/washington-to-santo-domingo) - [Flights from Raleigh (RDU) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/rdu/sdq/raleigh-to-santo-domingo) - [Flights from St. Louis (STL) to Santo Domingo (SDQ)](https://www.expedia.com/lp/flights/stl/sdq/st-louis-to-santo-domingo) \*Available to One Key members. ## Other language versions ```yaml hreflang: x-default: https://www.expedia.com/lp/flights/isp/sdq/islip-to-santo-domingo ar: https://www.expedia.sa/lp/flights/isp/sdq/islip-to-santo-domingo en-US: https://www.expedia.com/lp/flights/isp/sdq/islip-to-santo-domingo ```