$163 Cheap Flights from Lisbon (LIS) to Medellín (MDE)

View $163 flight on Fri, May 15, 2026Opens in a new window

Popular airlines from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)

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Cheap Flights from Lisbon to Medellín (LIS-MDE)

Prices were available within the past 7 days and start at $163 for one-way flights and $240 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAP Portugal
Sat, Mar 14 - Thu, Mar 19
LIS
Lisbon
MDE
Medellin
$240 Roundtrip, found 6 days ago
$240
Roundtrip
found 6 days ago
Select TAP Portugal flight, departing Sat, Mar 14 from Lisbon to Medellin, returning Thu, Mar 19, priced at $240 found 6 days ago
TAP Portugal
Sat, Feb 28 - Wed, Mar 4
LIS
Lisbon
MDE
Medellin
$244 Roundtrip, found 6 days ago
$244
Roundtrip
found 6 days ago
Select TAP Portugal flight, departing Sat, Feb 28 from Lisbon to Medellin, returning Wed, Mar 4, priced at $244 found 6 days ago
avianca
Sun, Feb 22 - Tue, Mar 3
LIS
Lisbon
MDE
Medellin
$255 Roundtrip, found 6 days ago
$255
Roundtrip
found 6 days ago
Select avianca flight, departing Sun, Feb 22 from Lisbon to Medellin, returning Tue, Mar 3, priced at $255 found 6 days ago
avianca
Sun, Feb 22 - Sun, Mar 1
LIS
Lisbon
MDE
Medellin
$256 Roundtrip, found 6 days ago
$256
Roundtrip
found 6 days ago
Select avianca flight, departing Sun, Feb 22 from Lisbon to Medellin, returning Sun, Mar 1, priced at $256 found 6 days ago
Iberia
Sat, Mar 14 - Thu, Mar 19
LIS
Lisbon
MDE
Medellin
$261 Roundtrip, found 6 days ago
$261
Roundtrip
found 6 days ago
Select Iberia flight, departing Sat, Mar 14 from Lisbon to Medellin, returning Thu, Mar 19, priced at $261 found 6 days ago
Iberia
Sat, Feb 28 - Wed, Mar 4
LIS
Lisbon
MDE
Medellin
$265 Roundtrip, found 6 days ago
$265
Roundtrip
found 6 days ago
Select Iberia flight, departing Sat, Feb 28 from Lisbon to Medellin, returning Wed, Mar 4, priced at $265 found 6 days ago
TAP Portugal
Sat, Feb 28 - Wed, Mar 4
LIS
Lisbon
MDE
Medellin
$273 Roundtrip, found 6 days ago
$273
Roundtrip
found 6 days ago
Select TAP Portugal flight, departing Sat, Feb 28 from Lisbon to Medellin, returning Wed, Mar 4, priced at $273 found 6 days ago
TAP Portugal
Fri, Apr 24 - Sat, May 9
LIS
Lisbon
MDE
Medellin
$274 Roundtrip, found 6 days ago
$274
Roundtrip
found 6 days ago
Select TAP Portugal flight, departing Fri, Apr 24 from Lisbon to Medellin, returning Sat, May 9, priced at $274 found 6 days ago
Air Europa
Fri, Apr 24 - Sat, May 9
LIS
Lisbon
MDE
Medellin
$318 Roundtrip, found 6 days ago
$318
Roundtrip
found 6 days ago
Select Air Europa flight, departing Fri, Apr 24 from Lisbon to Medellin, returning Sat, May 9, priced at $318 found 6 days ago
LATAM Airlines Group
Sun, Mar 1 - Sun, Mar 15
LIS
Lisbon
MDE
Medellin
$1,014 Roundtrip, found 5 days ago
$1,014
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Sun, Mar 1 from Lisbon to Medellin, returning Sun, Mar 15, priced at $1,014 found 5 days ago
Flights from Lisbon (LIS) to Medellín (MDE)
Origin airport
Humberto Delgado
Destination airport
José María Córdova Intl.
Roundtrip price
$240
Distance
4679 mi

Lisbon to Medellín Flights

The cheapest times to fly from Lisbon to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lisbon to Medellín are during the month of March. You can find some of the cheapest flights from Lisbon to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lisbon to Medellín

Sunday is one of the best days to book for cheap flights from Lisbon to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lisbon to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lisbon to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $163 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lisbon to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lisbon to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE) cost?
Grab a cheap one-way flight from $163 or cheap return flight from $240 from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
Flying in March is a great way to save, as it's the cheapest month for flights between LIS and MDE. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from LIS to MDE. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
You'll need to catch a flight with a layover if you're traveling from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from LIS to MDE?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
To arrive at Jose Maria Cordova Intl. Airport (MDE) on time, book a flight that leaves Humberto Delgado Airport (LIS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Holding off until right before your break to book your flight from LIS to MDE often results in higher prices. While you might find some last-minute discounts, they aren't always guaranteed. Keep your travel schedule open for a better chance of snagging a bargain.
Is it cheaper to book a LIS to MDE flight and hotel package?
Securing a LIS to MDE flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Choose from our wide range of hotels and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Humberto Delgado Airport (LIS) to Jose Maria Cordova Intl. Airport (MDE)?
Typically, you can modify or cancel your LIS to MDE flight. However, there may be additional charges, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you want more details, go to our Customer Service portal.

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*Available to One Key members.