--- title: "Minneapolis to Florence cheap flights from $287 (MSP to FLO) - Expedia" description: "Compare cheap Flights from Minneapolis (MSP) to Florence (FLO) start at $287 for one-way and $478 for round trip. Earn your airline miles on top of our rewards!" canonical: "https://www.expedia.com/lp/flights/msp/flo/minneapolis-to-florence" language: en-US market: US currency: USD prices_as_of: 2026-11-15T03:13:59Z --- # $287 Cheap Flights from Minneapolis (MSP) to Florence (FLO) ![A shopping mall with a Magnolia Mall sign and a Burlington store across the street.](https://images.trvl-media.com/place/6165602/4392990f-7038-4d9a-a654-83ae3a3dcd0f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) [View $287 flight on Thu, Feb 11, 2027](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:2/11/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:286.20&airProductToken=AQpoCjIIwYIBEgQyMTQwGMx8IOKaASiH%5F6QDMKSApQM4QkAAWAFqBUJBU0lDcghPV0FYWk5CWgoyCMGCARIENTg5MxjimgEg5XIopoGlAzDpgaUDOEJAAVgBagVCQVNJQ3IIT1dBWFpOQloSDAgBEAEYASoCQUEyABgBIgQIARABKAIoAygEMAs) ## Popular airlines from Minneapolis - St. Paul Intl. Airport (MSP) to Florence, SC (FLO-Florence Regional) [American Airlines](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:11/29/2026TANYT&leg2=from:FLO,to:MSP,departure:12/6/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) ### Be in the know Get alerts if flight prices drop or rise\* ### Book smarter Save up to 30% on select hotels after you book a flight\* ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## Cheap Flights from Minneapolis to Florence (MSP-FLO) Prices were available within the past 7 days and start at $287 for one-way flights and $478 for roundtrip, for the period specified. Prices and availability are subject to change. All deals One way Roundtrip [Select American Airlines flight, departing Thu, Dec 24 from Minneapolis to Florence, returning Tue, Jan 12, priced at $478 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:12/24/2026TANYT&leg2=from:FLO,to:MSP,departure:1/12/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:477.40&airProductToken=AQpoCjIIwYIBEgQyMDUyGMx8IOKaASjV0qADMP%5FToAM4QkAAWAFqBUJBU0lDcghPV0ZXWk5CWgoyCMGCARIENTk4NBjimgEg5XIovdWgAzD-1aADOEJAAVgBagVCQVNJQ3IIT1dGV1pOQloKaAoyCMGCARIENTgzOBjlciDimgEoiqiiAzDUqKIDOEJAAFgBagVCQVNJQ3IIT1dGV1VOQlgKMgjBggESBDMwOTkY4poBIMx8KICpogMwraqiAzhCQAFYAWoFQkFTSUNyCE9XRldVTkJYEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) Thu, Dec 24 - Tue, Jan 12 · MSP · FLO · Roundtrip [Select American Airlines flight, departing Fri, Jan 22 from Minneapolis to Florence, returning Sun, Jan 24, priced at $495 Found 6 days ago](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:1/22/2027TANYT&leg2=from:FLO,to:MSP,departure:1/24/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:494.40&airProductToken=AQpoCjIIwYIBEgQyMDUyGMx8IOKaASi8maMDMOiaowM4QkAAWAFqBUJBU0lDcghPV0ZXWk5CWgoyCMGCARIENTk4NBjimgEg5XIot5yjAzD1nKMDOEJAAVgBagVCQVNJQ3IIT1dGV1pOQloKaAoyCMGCARIENTk4NBjlciDimgEoz7OjAzCXtKMDOEJAAFgBagVCQVNJQ3IIT1dGV1pOQloKMgjBggESBDE2MzUY4poBIMx8KLK1owMw27ajAzhCQAFYAWoFQkFTSUNyCE9XRldaTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) Fri, Jan 22 - Sun, Jan 24 · MSP · FLO · Roundtrip [Select American Airlines flight, departing Sat, Nov 21 from Minneapolis to Florence, returning Wed, Nov 25, priced at $499 Found 3 days ago](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:11/21/2026TANYT&leg2=from:FLO,to:MSP,departure:11/25/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:498.40&airProductToken=AQpoCjIIwYIBEgQyMTQwGMx8IOKaASjQ5J0DMOzlnQM4QkAAWAFqBUJBU0lDcghRMEZXVU5CWgoyCMGCARIENTg5MxjimgEg5XIo5uadAzCm550DOEJAAVgBagVCQVNJQ3IIUTBGV1VOQloKaAoyCMGCARIENTgzOBjlciDimgEowYueAzCCjJ4DOEJAAFgBagVCQVNJQ3IIUTBGV1VOQloKMgjBggESBDMwOTkY4poBIMx8KMSMngMw8Y2eAzhCQAFYAWoFQkFTSUNyCFEwRldVTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) Sat, Nov 21 - Wed, Nov 25 · MSP · FLO · Roundtrip [Select American Airlines flight, departing Thu, Dec 24 from Minneapolis to Florence, returning Tue, Jan 12, priced at $506 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:12/24/2026TANYT&leg2=from:FLO,to:MSP,departure:1/12/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:505.71&airProductToken=AQpoCjIIwYIBEgQzMDk5GMx8IOKaASi%5F1KADMN%5FVoAM4QkAAWAFqBUJBU0lDcghPV0ZXWk5CWgoyCMGCARIENTg5MxjimgEg5XIoqNegAzDp16ADOEJAAVgBagVCQVNJQ3IIT1dGV1pOQloKmwEKMgjBggESBDU4MzgY5XIg4poBKIqoogMw1KiiAzhCQABYAWoFQkFTSUNyCE9XRldVTkJaCjIIwYIBEgQyNzg0GOKaASCuHCjdqaIDMOaqogM4QkABWAFqBUJBU0lDcghPV0ZXVU5CWgoxCMGCARIENDc0NhiuHCDMfCiKraIDMPetogM4QkABWAFqBUJBU0lDcghPVkFJVVNCWBIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) Thu, Dec 24 - Tue, Jan 12 · MSP · FLO · Roundtrip [Select American Airlines flight, departing Fri, Feb 19 from Minneapolis to Florence, returning Sat, Feb 27, priced at $517 Found 6 days ago](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:2/19/2027TANYT&leg2=from:FLO,to:MSP,departure:2/27/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:516.70&airProductToken=AQpoCjIIwYIBEgQyMDUyGMx8IOKaASiC1KUDMKTVpQM4QkAAWAFqBUJBU0lDcghPV0ZXWk5CWgoyCMGCARIENTk4NBjimgEg5XIo3dalAzCc16UDOEJAAVgBagVCQVNJQ3IIT1dGV1pOQloKmwEKMgjBggESBDU5ODQY5XIg4poBKLWxpgMw97GmAzhCQABYAWoFQkFTSUNyCE9XRldVTkJaCjIIwYIBEgQyMjk4GOKaASCuHCifsqYDMLGzpgM4QkABWAFqBUJBU0lDcghPV0ZXVU5CWgoxCMGCARIEMzQyNhiuHCDMfCjataYDML-2pgM4QkABWAFqBUJBU0lDcghPVkFJVVNCWBIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwCw) Fri, Feb 19 - Sat, Feb 27 · MSP · FLO · Roundtrip [Select American Airlines flight, departing Thu, Feb 11 from Minneapolis to Florence, returning Mon, Feb 15, priced at $530 Found 3 days ago](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:2/11/2027TANYT&leg2=from:FLO,to:MSP,departure:2/15/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:529.40&airProductToken=AQpoCjIIwYIBEgQyMTQwGMx8IOKaASiH%5F6QDMKSApQM4QkAAWAFqBUJBU0lDcghPV0ZXWk5CWgoyCMGCARIENTg5MxjimgEg5XIopoGlAzDpgaUDOEJAAVgBagVCQVNJQ3IIT1dGV1pOQloKaAoyCMGCARIENTk4NBjlciDimgEo9aqlAzC5q6UDOEJAAFgBagVCQVNJQ3IIUTBGV1pOQloKMgjBggESBDE2MzUY4poBIMx8KKmtpQMw0q6lAzhCQAFYAWoFQkFTSUNyCFEwRldaTkJaEgwIARABGAEqAkFBMgAYASIECAEQASgCKAMoBDAL) Thu, Feb 11 - Mon, Feb 15 · MSP · FLO · Roundtrip [Select American Airlines flight, departing Thu, Dec 24 from Minneapolis to Florence, returning Tue, Jan 12, priced at $530 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:12/24/2026TANYT&leg2=from:FLO,to:MSP,departure:1/12/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:529.71&airProductToken=AQqbAQoxCMGCARIENDY5OBjMfCCuHCjS0qADMNzToAM4QkAAWAFqBUJBU0lDcghPVkFIWFNCWAoyCMGCARIEMjUxNBiuHCDimgEogNagAzD-1qADOEJAAVgBagVCQVNJQ3IIT1dGV1pOQloKMgjBggESBDU4OTMY4poBIOVyKKjXoAMw6degAzhCQAFYAWoFQkFTSUNyCE9XRldaTkJaCmgKMgjBggESBDU4MzgY5XIg4poBKIqoogMw1KiiAzhCQABYAWoFQkFTSUNyCE9XRldVTkJYCjIIwYIBEgQzMDk5GOKaASDMfCiAqaIDMK2qogM4QkABWAFqBUJBU0lDcghPV0ZXVU5CWBIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) Thu, Dec 24 - Tue, Jan 12 · MSP · FLO · Roundtrip [Select American Airlines flight, departing Sun, Mar 7 from Minneapolis to Florence, returning Sat, Mar 13, priced at $547 Found 5 days ago](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:3/7/2027TANYT&leg2=from:FLO,to:MSP,departure:3/13/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:546.40&airProductToken=AQpoCjIIwYIBEgQyMDUyGMx8IOKaASiCiKcDMKSJpwM4QkAAWAFqBUJBU0lDcghPV0ZXWk5CWgoyCMGCARIENTk4NBjimgEg5XIo3YqnAzCci6cDOEJAAVgBagVCQVNJQ3IIT1dGV1pOQloKaAoyCMGCARIENTgzOBjlciDimgEowcqnAzCKy6cDOEJAAFgBagVCQVNJQ3IITjBGV1VOQloKMgjBggESBDMzMTMY4poBIMx8KOTMpwMwkc6nAzhCQAFYAWoFQkFTSUNyCE4wRldVTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) Sun, Mar 7 - Sat, Mar 13 · MSP · FLO · Roundtrip [Select American Airlines flight, departing Thu, Dec 24 from Minneapolis to Florence, returning Tue, Jan 12, priced at $558 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:12/24/2026TANYT&leg2=from:FLO,to:MSP,departure:1/12/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:558.00&airProductToken=AQqbAQoxCMGCARIENDY5OBjMfCCuHCjS0qADMNzToAM4QkAAWAFqBUJBU0lDcghPVkFIWFNCWAoyCMGCARIEMjUxNBiuHCDimgEogNagAzD-1qADOEJAAVgBagVCQVNJQ3IIT1dGV1pOQloKMgjBggESBDU4OTMY4poBIOVyKKjXoAMw6degAzhCQAFYAWoFQkFTSUNyCE9XRldaTkJaCpsBCjIIwYIBEgQ1ODM4GOVyIOKaASiKqKIDMNSoogM4QkAAWAFqBUJBU0lDcghPV0ZXVU5CWgoyCMGCARIEMjc4NBjimgEgrhwo3amiAzDmqqIDOEJAAVgBagVCQVNJQ3IIT1dGV1VOQloKMQjBggESBDQ3NDYYrhwgzHwoiq2iAzD3raIDOEJAAVgBagVCQVNJQ3IIT1ZBSVVTQlgSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) Thu, Dec 24 - Tue, Jan 12 · MSP · FLO · Roundtrip [Select American Airlines flight, departing Fri, Nov 20 from Minneapolis to Florence, returning Sun, Nov 22, priced at $565 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:MSP,to:FLO,departure:11/20/2026TANYT&leg2=from:FLO,to:MSP,departure:11/22/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:564.40&airProductToken=AQpoCjIIwYIBEgQyMDUyGMx8IOKaASiR1J0DMMPVnQM4QkAAWAFqBUJBU0lDcghRMEZXWk5CWgoyCMGCARIENTk4NBjimgEg5XIo%5FdadAzC9150DOEJAAVgBagVCQVNJQ3IIUTBGV1pOQloKaAoyCMGCARIENTgzOBjlciDimgEo4emdAzCi6p0DOEJAAFgBagVCQVNJQ3IIUTBGV1pOQloKMgjBggESBDMwOTkY4poBIMx8KOTqnQMwkeydAzhCQAFYAWoFQkFTSUNyCFEwRldaTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) Fri, Nov 20 - Sun, Nov 22 · MSP · FLO · Roundtrip ## Book with confidence ### Minneapolis to Florence Flights #### The cheapest times to fly from Minneapolis to Florence On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Minneapolis to Florence are during the month of December. You can find some of the cheapest flights from Minneapolis to Florence with Expedia's search tool and vast selection of airlines. #### The best time to book a flight from Minneapolis to Florence Sunday is one of the best days to book for cheap flights from Minneapolis to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. #### How to find cheap round-trip tickets from Minneapolis to Florence Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Minneapolis to Florence in 2026\. You can also book with separate airlines for your outbound and return journeys, from $287 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Minneapolis to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Minneapolis to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. *\*Terms apply.* *Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages.* ## Frequently Asked Questions ### How much does a flight from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) cost? You can find cheap one-way flights from $287 and cheap return flights $478 Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) with Expedia. One-way flights usually range from $437 to $547, and return flights typically cost between $440 and $1111\. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) ticket fares go up or down. *\*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.* ### What is the cheapest month to fly from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional)? The cheapest month to fly from MSP to FLO is December when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route. ### Which airlines fly direct from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional)? Enter MSP to FLO and your travel dates, then apply the 'Nonstop' filter to see only direct flights. ### What is the cheapest airline that flies from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional)? American Airlines is one of the cheapest airlines offering connecting flights from Minneapolis, MN (MSP) to Florence, SC (FLO), with round-trip tickets starting from around $362.36 with a layover in O'Hare Intl. (ORD). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget. *\*Prices based on flights available on Expedia in the last year.* ### How do I find cheap flights from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional)? To find a cheap flight from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up [Price Tracking](https://www.expedia.com/why/price-tracking) and receive alerts when fares go up or down. ### What is the best time to fly from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional)? The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience. ### What is the earliest flight from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional)? The earliest flight from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) typically departs at around 5:20 AM, operated by American Airlines. This seasonal service is available in September, allowing you to maximize your time in Florence. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search. ### What are the most popular departure times for flights from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional)? The most popular departure times for flights from Minneapolis - St. Paul Intl. (MSP) to Florence Regional (FLO) are in the late morning, from 9am to noon. About 34% of passengers prefer this time window. Many major carriers, including American Airlines and American Airlines, offer flights during this window. This timing is popular because it allows you to start your day without rushing. ### How long does it take to fly from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional)? Flying from MSP to FLO with a connection usually takes about 5 hours, traveling roughly 1,028 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic. ### Can you fly business or first class from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional)? Select the "Business class" and "First class" filters when looking for MSP to FLO flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip. ### How do I earn miles on a Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) flight with Expedia? It's easy to earn miles on a Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of [One Key™](https://www.expedia.com/welcome-one-key), you can also earn OneKeyCash™\* on top of your airline miles when you book with Expedia. \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands. ### What airports do you fly into for Florence from Minneapolis - St. Paul Intl. (MSP)? From Minneapolis - St. Paul Intl. (MSP), you can fly into Florence Regional (FLO) and Peretola (FLR) in Florence. Some flights may connect through major hubs like O'Hare Intl. (ORD) before reaching Florence. Compare routes and airports on Expedia to find the best flight options for your travel plans. ### Is it cheaper to buy a plane ticket from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) at the last minute? Typically, booking a last minute flight from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare. ### Is it cheaper to book a Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) flight and hotel package? Securing a Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars. ### Can I cancel or change the date of my flight from Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional)? If you booked your Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.) to Florence, SC (FLO-Florence Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in [your itinerary](https://www.expedia.com/trips) or confirmation email. Or, head to our [Customer Service portal](https://www.expedia.com/helpcenter/) if you'd like more information. ## Travel information | Origin airport | Minneapolis - St. Paul Intl. Airport | | ------------------- | ------------------------------------ | | Destination airport | Florence, SC | | Distance | 1,027 miles away | | Airlines serving | American Airlines | | Popular airline | American Airlines | | Roundtrip price | $478 | ## Explore a world of travel with Expedia - [Flights](?equalTargetTab=tab-0) - [Flights from Sarasota (SRQ) to Florence (FLO)](https://www.expedia.com/lp/flights/srq/flo/sarasota-to-florence) - [Flights from Fort Walton Beach (VPS) to Florence (FLO)](https://www.expedia.com/lp/flights/vps/flo/fort-walton-beach-to-florence) - [Flights from Augusta (AGS) to Florence (FLO)](https://www.expedia.com/lp/flights/ags/flo/augusta-to-florence) - [Flights from Columbia (CAE) to Florence (FLO)](https://www.expedia.com/lp/flights/cae/flo/columbia-to-florence) - [Flights from Rzeszow (RZE) to Florence (FLO)](https://www.expedia.com/lp/flights/rze/flo/rzeszow-to-florence) - [Flights from Greenville (GSP) to Florence (FLO)](https://www.expedia.com/lp/flights/gsp/flo/greenville-to-florence) - [Flights from San Diego (SAN) to Florence (FLO)](https://www.expedia.com/lp/flights/san/flo/san-diego-to-florence) - [Flights from Anchorage (ANC) to Florence (FLO)](https://www.expedia.com/lp/flights/anc/flo/anchorage-to-florence) - [Flights from Buffalo (BUF) to Florence (FLO)](https://www.expedia.com/lp/flights/buf/flo/buffalo-to-florence) - [Flights from Fort Lauderdale (FLL) to Florence (FLO)](https://www.expedia.com/lp/flights/fll/flo/fort-lauderdale-to-florence) - [Flights from New York (NYC) to Florence (FLO)](https://www.expedia.com/lp/flights/nyc/flo/new-york-to-florence) - [Flights from Louisville (SDF) to Florence (FLO)](https://www.expedia.com/lp/flights/sdf/flo/louisville-to-florence) - [Flights from Albany (ALB) to Florence (FLO)](https://www.expedia.com/lp/flights/alb/flo/albany-to-florence) - [Flights from Birmingham (BHM) to Florence (FLO)](https://www.expedia.com/lp/flights/bhm/flo/birmingham-to-florence) - [Flights from Nairobi (NBO) to Florence (FLO)](https://www.expedia.com/lp/flights/nbo/flo/nairobi-to-florence) - [Flights from South Bend (SBN) to Florence (FLO)](https://www.expedia.com/lp/flights/sbn/flo/south-bend-to-florence) - [Flights from El Paso (ELP) to Florence (FLO)](https://www.expedia.com/lp/flights/elp/flo/el-paso-to-florence) - [Flights from Wilmington (ILM) to Florence (FLO)](https://www.expedia.com/lp/flights/ilm/flo/wilmington-to-florence) - [Flights from West Palm Beach (PBI) to Florence (FLO)](https://www.expedia.com/lp/flights/pbi/flo/west-palm-beach-to-florence) - [Flights from Savannah (SAV) to Florence (FLO)](https://www.expedia.com/lp/flights/sav/flo/savannah-to-florence) - [Flights from Boston (BOS) to Florence (FLO)](https://www.expedia.com/lp/flights/bos/flo/boston-to-florence) - [Flights from Salt Lake City (SLC) to Florence (FLO)](https://www.expedia.com/lp/flights/slc/flo/salt-lake-city-to-florence) - [Flights from San Antonio (SAT) to Florence (FLO)](https://www.expedia.com/lp/flights/sat/flo/san-antonio-to-florence) - [Flights from Charlotte (CLT) to Florence (FLO)](https://www.expedia.com/lp/flights/clt/flo/charlotte-to-florence) - [Flights from New Orleans (MSY) to Florence (FLO)](https://www.expedia.com/lp/flights/msy/flo/new-orleans-to-florence) - [Flights from Dallas (DFW) to Florence (FLO)](https://www.expedia.com/lp/flights/dfw/flo/dallas-to-florence) - [Flights from Denver (DEN) to Florence (FLO)](https://www.expedia.com/lp/flights/den/flo/denver-to-florence) - [Flights from Latrobe (LBE) to Florence (FLO)](https://www.expedia.com/lp/flights/lbe/flo/latrobe-to-florence) - [Flights from Orlando (MCO) to Florence (FLO)](https://www.expedia.com/lp/flights/mco/flo/orlando-to-florence) - [Flights from Sacramento (SMF) to Florence (FLO)](https://www.expedia.com/lp/flights/smf/flo/sacramento-to-florence) - [Flights from Cleveland (CLE) to Florence (FLO)](https://www.expedia.com/lp/flights/cle/flo/cleveland-to-florence) - [Flights from Myrtle Beach (MYR) to Florence (FLO)](https://www.expedia.com/lp/flights/myr/flo/myrtle-beach-to-florence) - [Flights from Dothan (DHN) to Florence (FLO)](https://www.expedia.com/lp/flights/dhn/flo/dothan-to-florence) - [Flights from Gainesville (GNV) to Florence (FLO)](https://www.expedia.com/lp/flights/gnv/flo/gainesville-to-florence) - [Flights from Tampa (TPA) to Florence (FLO)](https://www.expedia.com/lp/flights/tpa/flo/tampa-to-florence) - [Flights from Greensboro (GSO) to Florence (FLO)](https://www.expedia.com/lp/flights/gso/flo/greensboro-to-florence) - [Flights from St. Louis (STL) to Florence (FLO)](https://www.expedia.com/lp/flights/stl/flo/st-louis-to-florence) - [Flights from London (LHR) to Florence (FLO)](https://www.expedia.com/lp/flights/lhr/flo/london-to-florence) - [Flights from San Francisco (SFO) to Florence (FLO)](https://www.expedia.com/lp/flights/sfo/flo/san-francisco-to-florence) - [Flights from Lancaster (LNS) to Florence (FLO)](https://www.expedia.com/lp/flights/lns/flo/lancaster-to-florence) - [Flights from Philadelphia (PHL) to Florence (FLO)](https://www.expedia.com/lp/flights/phl/flo/philadelphia-to-florence) - [Flights from Las Vegas (LAS) to Florence (FLO)](https://www.expedia.com/lp/flights/las/flo/las-vegas-to-florence) - [Flights from Phoenix (PHX) to Florence (FLO)](https://www.expedia.com/lp/flights/phx/flo/phoenix-to-florence) - [Flights from Hartford (BDL) to Florence (FLO)](https://www.expedia.com/lp/flights/bdl/flo/hartford-to-florence) - [Flights from Knoxville (TYS) to Florence (FLO)](https://www.expedia.com/lp/flights/tys/flo/knoxville-to-florence) - [Flights from Milwaukee (MKE) to Florence (FLO)](https://www.expedia.com/lp/flights/mke/flo/milwaukee-to-florence) - [Flights from Rochester (ROC) to Florence (FLO)](https://www.expedia.com/lp/flights/roc/flo/rochester-to-florence) - [Flights from Richmond (RIC) to Florence (FLO)](https://www.expedia.com/lp/flights/ric/flo/richmond-to-florence) - [Flights from Dayton (DAY) to Florence (FLO)](https://www.expedia.com/lp/flights/day/flo/dayton-to-florence) - [Flights from Missoula (MSO) to Florence (FLO)](https://www.expedia.com/lp/flights/mso/flo/missoula-to-florence) - [Flights from Indianapolis (IND) to Florence (FLO)](https://www.expedia.com/lp/flights/ind/flo/indianapolis-to-florence) - [Flights from Memphis (MEM) to Florence (FLO)](https://www.expedia.com/lp/flights/mem/flo/memphis-to-florence) - [Flights from Oklahoma City (OKC) to Florence (FLO)](https://www.expedia.com/lp/flights/okc/flo/oklahoma-city-to-florence) - [Flights from Tallahassee (TLH) to Florence (FLO)](https://www.expedia.com/lp/flights/tlh/flo/tallahassee-to-florence) - [Flights from Tulsa (TUL) to Florence (FLO)](https://www.expedia.com/lp/flights/tul/flo/tulsa-to-florence) - [Flights from Lexington (LEX) to Florence (FLO)](https://www.expedia.com/lp/flights/lex/flo/lexington-to-florence) - [Flights from Fayetteville (XNA) to Florence (FLO)](https://www.expedia.com/lp/flights/xna/flo/fayetteville-to-florence) - [Flights from Columbus (CMH) to Florence (FLO)](https://www.expedia.com/lp/flights/cmh/flo/columbus-to-florence) - [Flights from New York (JFK) to Florence (FLO)](https://www.expedia.com/lp/flights/jfk/flo/new-york-to-florence) - [Flights from Little Rock (LIT) to Florence (FLO)](https://www.expedia.com/lp/flights/lit/flo/little-rock-to-florence) - [Flights from Charleston (CHS) to Florence (FLO)](https://www.expedia.com/lp/flights/chs/flo/charleston-to-florence) - [Flights from Washington (IAD) to Florence (FLO)](https://www.expedia.com/lp/flights/iad/flo/washington-to-florence) - [Flights from Appleton (ATW) to Florence (FLO)](https://www.expedia.com/lp/flights/atw/flo/appleton-to-florence) - [Flights from Baltimore (BWI) to Florence (FLO)](https://www.expedia.com/lp/flights/bwi/flo/baltimore-to-florence) - [Flights from Pensacola (PNS) to Florence (FLO)](https://www.expedia.com/lp/flights/pns/flo/pensacola-to-florence) - [Flights from Allentown (ABE) to Florence (FLO)](https://www.expedia.com/lp/flights/abe/flo/allentown-to-florence) - [Flights from Portland (PDX) to Florence (FLO)](https://www.expedia.com/lp/flights/pdx/flo/portland-to-florence) - [Flights from Pittsburgh (PIT) to Florence (FLO)](https://www.expedia.com/lp/flights/pit/flo/pittsburgh-to-florence) - [Flights from New Haven (HVN) to Florence (FLO)](https://www.expedia.com/lp/flights/hvn/flo/new-haven-to-florence) - [Flights from Newark Liberty Intl. Airport (EWR) to Florence (FLO)](https://www.expedia.com/lp/flights/ewr/flo/newark-liberty-intl-airport-to-florence) - [Flights from Detroit (DTW) to Florence (FLO)](https://www.expedia.com/lp/flights/dtw/flo/detroit-to-florence) - [Flights from Huntsville (HSV) to Florence (FLO)](https://www.expedia.com/lp/flights/hsv/flo/huntsville-to-florence) - [Flights from Providence (PVD) to Florence (FLO)](https://www.expedia.com/lp/flights/pvd/flo/providence-to-florence) - [Flights from Jacksonville (JAX) to Florence (FLO)](https://www.expedia.com/lp/flights/jax/flo/jacksonville-to-florence) - [Flights from Boston (BOS) to Myrtle Beach (MYR)](https://www.expedia.com/lp/flights/bos/myr/boston-to-myrtle-beach) - [Flights from Tucson (TUS) to Florence (FLO)](https://www.expedia.com/lp/flights/tus/flo/tucson-to-florence) - [Flights from Mobile (MOB) to Florence (FLO)](https://www.expedia.com/lp/flights/mob/flo/mobile-to-florence) - [Flights from New York (LGA) to Florence (FLO)](https://www.expedia.com/lp/flights/lga/flo/new-york-to-florence) - [Flights from Asheville (AVL) to Florence (FLO)](https://www.expedia.com/lp/flights/avl/flo/asheville-to-florence) - [Flights from Syracuse (SYR) to Florence (FLO)](https://www.expedia.com/lp/flights/syr/flo/syracuse-to-florence) - [Flights from Austin (AUS) to Florence (FLO)](https://www.expedia.com/lp/flights/aus/flo/austin-to-florence) - [Flights from Miami (MIA) to Florence (FLO)](https://www.expedia.com/lp/flights/mia/flo/miami-to-florence) - [Flights from Newburgh (SWF) to Florence (FLO)](https://www.expedia.com/lp/flights/swf/flo/newburgh-to-florence) - [Flights from Colorado Springs (COS) to Florence (FLO)](https://www.expedia.com/lp/flights/cos/flo/colorado-springs-to-florence) - [Flights from Nashville (BNA) to Florence (FLO)](https://www.expedia.com/lp/flights/bna/flo/nashville-to-florence) - [Flights from Los Angeles (LAX) to Florence (FLO)](https://www.expedia.com/lp/flights/lax/flo/los-angeles-to-florence) - [Flights from Houston (IAH) to Florence (FLO)](https://www.expedia.com/lp/flights/iah/flo/houston-to-florence) - [Flights from Fresno (FAT) to Florence (FLO)](https://www.expedia.com/lp/flights/fat/flo/fresno-to-florence) - [Flights from Kansas City (MCI) to Florence (FLO)](https://www.expedia.com/lp/flights/mci/flo/kansas-city-to-florence) - [Flights from Chicago (ORD) to Florence (FLO)](https://www.expedia.com/lp/flights/ord/flo/chicago-to-florence) - [Flights from San Luis Obispo (SBP) to Florence (FLO)](https://www.expedia.com/lp/flights/sbp/flo/san-luis-obispo-to-florence) - [Flights from Chattanooga (CHA) to Florence (FLO)](https://www.expedia.com/lp/flights/cha/flo/chattanooga-to-florence) - [Flights from Evansville (EVV) to Florence (FLO)](https://www.expedia.com/lp/flights/evv/flo/evansville-to-florence) - [Flights from Eugene (EUG) to Florence (FLO)](https://www.expedia.com/lp/flights/eug/flo/eugene-to-florence) - [Flights from Atlanta (ATL) to Florence (FLO)](https://www.expedia.com/lp/flights/atl/flo/atlanta-to-florence) - [Flights from Washington (DCA) to Florence (FLO)](https://www.expedia.com/lp/flights/dca/flo/washington-to-florence) - [Flights from Cincinnati (CVG) to Florence (FLO)](https://www.expedia.com/lp/flights/cvg/flo/cincinnati-to-florence) - [Flights from Seattle (SEA) to Florence (FLO)](https://www.expedia.com/lp/flights/sea/flo/seattle-to-florence) - [Flights from Fort Myers (RSW) to Florence (FLO)](https://www.expedia.com/lp/flights/rsw/flo/fort-myers-to-florence) - [Flights from Norfolk (ORF) to Florence (FLO)](https://www.expedia.com/lp/flights/orf/flo/norfolk-to-florence) \*Available to One Key members. ## Other language versions ```yaml hreflang: x-default: https://www.expedia.com/lp/flights/msp/flo/minneapolis-to-florence en-US: https://www.expedia.com/lp/flights/msp/flo/minneapolis-to-florence ar: https://www.expedia.sa/lp/flights/msp/flo/minneapolis-to-florence es: https://www.expedia.com/es/lp/vuelos/msp/flo/minneapolis-a-florence en-SA: https://www.expedia.sa/en/lp/flights/msp/flo/minneapolis-to-florence ```