$266 Cheap Flights from Portland (PDX) to Panama City (PTY)

View $266 flight on Thu, Feb 19, 2026Opens in a new window

Popular airlines from Portland International Airport (PDX) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Portland to Panama City (PDX-PTY)

Prices were available within the past 7 days and start at $266 for one-way flights and $577 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Thu, Feb 19 - Thu, Feb 26
PDX
Portland
PTY
Panama City
$577 Roundtrip, just found
$577
Roundtrip
just found
Select United flight, departing Thu, Feb 19 from Portland to Panama City, returning Thu, Feb 26, priced at $577 just found
United
Tue, Feb 24 - Tue, Mar 24
PDX
Portland
PTY
Panama City
$581 Roundtrip, found 12 hours ago
$581
Roundtrip
found 12 hours ago
Select United flight, departing Tue, Feb 24 from Portland to Panama City, returning Tue, Mar 24, priced at $581 found 12 hours ago
United
Wed, Jan 28 - Wed, Feb 11
PDX
Portland
PTY
Panama City
$585 Roundtrip, found 17 hours ago
$585
Roundtrip
found 17 hours ago
Select United flight, departing Wed, Jan 28 from Portland to Panama City, returning Wed, Feb 11, priced at $585 found 17 hours ago
United
Mon, Nov 17 - Mon, Apr 27
PDX
Portland
PTY
Panama City
$596 Roundtrip, found 1 day ago
$596
Roundtrip
found 1 day ago
Select United flight, departing Mon, Nov 17 from Portland to Panama City, returning Mon, Apr 27, priced at $596 found 1 day ago
United
Wed, Nov 12 - Tue, Nov 18
PDX
Portland
PTY
Panama City
$598 Roundtrip, found 2 days ago
$598
Roundtrip
found 2 days ago
Select United flight, departing Wed, Nov 12 from Portland to Panama City, returning Tue, Nov 18, priced at $598 found 2 days ago
United
Sat, Jan 24 - Sat, Jan 31
PDX
Portland
PTY
Panama City
$605 Roundtrip, found 17 hours ago
$605
Roundtrip
found 17 hours ago
Select United flight, departing Sat, Jan 24 from Portland to Panama City, returning Sat, Jan 31, priced at $605 found 17 hours ago
Delta
Tue, Jan 6 - Wed, Jan 14
PDX
Portland
PTY
Panama City
$628 Roundtrip, found 6 hours ago
$628
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Jan 6 from Portland to Panama City, returning Wed, Jan 14, priced at $628 found 6 hours ago
American Airlines
Tue, Jan 6 - Wed, Jan 14
PDX
Portland
PTY
Panama City
$633 Roundtrip, found 6 hours ago
$633
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Jan 6 from Portland to Panama City, returning Wed, Jan 14, priced at $633 found 6 hours ago
Copa
Thu, Feb 19 - Thu, Feb 26
PDX
Portland
PTY
Panama City
$740 Roundtrip, just found
$740
Roundtrip
just found
Select Copa flight, departing Thu, Feb 19 from Portland to Panama City, returning Thu, Feb 26, priced at $740 just found
avianca
Sat, Sep 5 - Sun, Sep 13
PDX
Portland
PTY
Panama City
$1,032 Roundtrip, found 6 days ago
$1,032
Roundtrip
found 6 days ago
Select avianca flight, departing Sat, Sep 5 from Portland to Panama City, returning Sun, Sep 13, priced at $1,032 found 6 days ago

Find the cheapest month to fly from Portland (PDX) to Panama City (PTY)

August is typically the cheapest month to fly

From $480 - $914 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $598
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $598

Frequently asked questions

How much does a flight from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY) cost?
Secure a cheap one-way flight from $266 or cheap return flight from $577 from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
February is the least expensive month to fly from PDX to PTY. Avoiding peak travel times is often the key to landing a great deal.
What is the cheapest airline that flies from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
To find the cheapest airline flying from PDX to PTY, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
You'll need to catch a flight with a layover when traveling from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from PDX to PTY?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
To reach Tocumen Intl. Airport (PTY) without delays, select a flight that leaves Portland Intl. Airport (PDX) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute bookings from PDX to PTY are usually more expensive. To secure the lowest rates, start searching for flights early. That being said, if you're flexible with your travel plans, it's possible to land a cheap fare right before your trip.
Is it cheaper to book a PDX to PTY flight and hotel package?
You'll generally save money by securing a PDX to PTY flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After choosing your ideal flights and accommodations, consider other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Portland Intl. Airport (PDX) to Tocumen Intl. Airport (PTY)?
You can usually reschedule or cancel your PDX to PTY flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Portland Intl.
Destination airport
Tocumen Intl.
Airlines serving
American Airlines, Copa, Delta, United, avianca
Roundtrip price
$577
Distance
3589 mi

Book with confidence

Portland to Panama City Flights

The cheapest times to fly from Portland to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Portland to Panama City are during the month of February. You can find some of the cheapest flights from Portland to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Portland to Panama City

Sunday is one of the best days to book for cheap flights from Portland to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Portland to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Portland to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $266 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Portland to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Portland to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Portland to Panama City Flights

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*Available to One Key members.