$222 Cheap Flights from Pittsburgh (PIT) to Florence (FLO)

View $222 flight on Tue, Sep 15, 2026Opens in a new window

Popular airlines from Pittsburgh Intl. Airport (PIT) to Florence, SC (FLO-Florence Regional)

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Cheap Flights from Pittsburgh to Florence (PIT-FLO)

Prices were available within the past 7 days and start at $222 for one-way flights and $464 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Apr 21 - Sat, May 2
PIT
Pittsburgh
FLO
Florence
$464 Roundtrip, found 5 days ago
$464
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Apr 21 from Pittsburgh to Florence, returning Sat, May 2, priced at $464 found 5 days ago
American Airlines
Mon, Apr 20 - Sat, May 2
PIT
Pittsburgh
FLO
Florence
$470 Roundtrip, found 5 days ago
$470
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Apr 20 from Pittsburgh to Florence, returning Sat, May 2, priced at $470 found 5 days ago
American Airlines
Thu, Apr 30 - Sat, May 9
PIT
Pittsburgh
FLO
Florence
$475 Roundtrip, found 14 hours ago
$475
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Thu, Apr 30 from Pittsburgh to Florence, returning Sat, May 9, priced at $475 found 14 hours ago
American Airlines
Thu, Apr 23 - Sat, May 2
PIT
Pittsburgh
FLO
Florence
$475 Roundtrip, found 5 days ago
$475
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Apr 23 from Pittsburgh to Florence, returning Sat, May 2, priced at $475 found 5 days ago
American Airlines
Tue, Apr 21 - Thu, Apr 30
PIT
Pittsburgh
FLO
Florence
$480 Roundtrip, found 5 days ago
$480
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Apr 21 from Pittsburgh to Florence, returning Thu, Apr 30, priced at $480 found 5 days ago
American Airlines
Thu, Apr 23 - Fri, May 1
PIT
Pittsburgh
FLO
Florence
$486 Roundtrip, found 5 days ago
$486
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Apr 23 from Pittsburgh to Florence, returning Fri, May 1, priced at $486 found 5 days ago
American Airlines
Thu, Apr 23 - Thu, Apr 30
PIT
Pittsburgh
FLO
Florence
$491 Roundtrip, found 5 days ago
$491
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Apr 23 from Pittsburgh to Florence, returning Thu, Apr 30, priced at $491 found 5 days ago
American Airlines
Thu, Apr 30 - Sat, May 9
PIT
Pittsburgh
FLO
Florence
$519 Roundtrip, found 14 hours ago
$519
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Thu, Apr 30 from Pittsburgh to Florence, returning Sat, May 9, priced at $519 found 14 hours ago
American Airlines
Fri, Apr 24 - Sat, May 2
PIT
Pittsburgh
FLO
Florence
$519 Roundtrip, found 5 days ago
$519
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Apr 24 from Pittsburgh to Florence, returning Sat, May 2, priced at $519 found 5 days ago
American Airlines
Fri, Apr 24 - Tue, Apr 28
PIT
Pittsburgh
FLO
Florence
$524 Roundtrip, found 5 days ago
$524
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Apr 24 from Pittsburgh to Florence, returning Tue, Apr 28, priced at $524 found 5 days ago
Flights from Pittsburgh (PIT) to Florence (FLO)
Origin airport
Pittsburgh Intl.
Destination airport
Florence Regional
Airlines serving
American Airlines
Roundtrip price
$464
Distance
436 mi

Pittsburgh to Florence Flights

The cheapest times to fly from Pittsburgh to Florence

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pittsburgh to Florence are during the month of April. You can find some of the cheapest flights from Pittsburgh to Florence with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pittsburgh to Florence

Sunday is one of the best days to book for cheap flights from Pittsburgh to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pittsburgh to Florence

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pittsburgh to Florence in 2026. You can also book with separate airlines for your outbound and return journeys, from $222 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pittsburgh to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pittsburgh to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO) cost?
Get a cheap one-way flight from $222 or cheap return flight from $464 from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO)?
Planning your getaway for April is a good way to save, as it's the cheapest month for flights between PIT and FLO. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO)?
To find the cheapest airline that'll fly you from PIT to FLO, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO)?
You'll need to book a flight with a layover when traveling from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from PIT to FLO?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can change based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO)?
To reach Florence Regional Airport (FLO) on time, choose a flight that leaves from Pittsburgh Intl. Airport (PIT) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO) last-minute?
Booking your plane ticket from PIT to FLO just before your trip is generally more expensive. However, if there's some wiggle room with your schedule, you could grab a cheap last-minute fare.
Is it cheaper to book a PIT to FLO flight and hotel package?
Compared with arranging hotels and flights separately, booking a PIT to FLO flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one easy place takes the hassle out of planning your trip. Simply secure your flights and select from our wide range of hotels, then customize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Pittsburgh Intl. Airport (PIT) to Florence Regional Airport (FLO)?
In most instances, you can reschedule or cancel your PIT to FLO flight. However, additional fees may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you want more details, head to our Customer Service portal.

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*Available to One Key members.