$637 Cheap Flights from Panama City (PTY) to Islip (ISP)

View $637 flight on Sun, Apr 12, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP)

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Cheap Flights from Panama City to Islip (PTY-ISP)

Prices were available within the past 7 days and start at $637 for one-way flights and $1,415 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Thu, Jun 18 - Sun, Jun 21
PTY
Panama City
ISP
Islip
$1,415 Roundtrip, found 2 days ago
$1,415
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Jun 18 from Panama City to Islip, returning Sun, Jun 21, priced at $1,415 found 2 days ago
avianca
Thu, Jun 18 - Sun, Jun 21
PTY
Panama City
ISP
Islip
$1,416 Roundtrip, found 2 days ago
$1,416
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Jun 18 from Panama City to Islip, returning Sun, Jun 21, priced at $1,416 found 2 days ago
avianca
Thu, Jun 18 - Sun, Jun 21
PTY
Panama City
ISP
Islip
$1,437 Roundtrip, found 2 days ago
$1,437
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Jun 18 from Panama City to Islip, returning Sun, Jun 21, priced at $1,437 found 2 days ago
avianca
Thu, Jun 18 - Sun, Jun 21
PTY
Panama City
ISP
Islip
$1,438 Roundtrip, found 2 days ago
$1,438
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Jun 18 from Panama City to Islip, returning Sun, Jun 21, priced at $1,438 found 2 days ago
avianca
Thu, Jun 18 - Sun, Jun 21
PTY
Panama City
ISP
Islip
$1,451 Roundtrip, found 2 days ago
$1,451
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Jun 18 from Panama City to Islip, returning Sun, Jun 21, priced at $1,451 found 2 days ago
avianca
Thu, Jun 18 - Sun, Jun 21
PTY
Panama City
ISP
Islip
$1,473 Roundtrip, found 2 days ago
$1,473
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Jun 18 from Panama City to Islip, returning Sun, Jun 21, priced at $1,473 found 2 days ago
avianca
Thu, Jun 18 - Sun, Jun 21
PTY
Panama City
ISP
Islip
$1,620 Roundtrip, found 2 days ago
$1,620
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Jun 18 from Panama City to Islip, returning Sun, Jun 21, priced at $1,620 found 2 days ago
avianca
Thu, Jun 18 - Sun, Jun 21
PTY
Panama City
ISP
Islip
$1,621 Roundtrip, found 2 days ago
$1,621
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Jun 18 from Panama City to Islip, returning Sun, Jun 21, priced at $1,621 found 2 days ago
avianca
Thu, Jun 18 - Sun, Jun 21
PTY
Panama City
ISP
Islip
$1,656 Roundtrip, found 2 days ago
$1,656
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Jun 18 from Panama City to Islip, returning Sun, Jun 21, priced at $1,656 found 2 days ago
avianca
Thu, Jun 18 - Sun, Jun 21
PTY
Panama City
ISP
Islip
$1,968 Roundtrip, found 2 days ago
$1,968
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Jun 18 from Panama City to Islip, returning Sun, Jun 21, priced at $1,968 found 2 days ago

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Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP) cost?
Grab a cheap one-way flight from $637 or cheap return flight from $1,415 from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP)?
Flying in June is a great way to save, as it's the cheapest month for flights between PTY and ISP. You'll usually find the lowest fares during the off-season.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP)?
To find the cheapest airline flying from PTY to ISP, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP)?
There aren't any daily direct flights departing from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from PTY to ISP?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can change depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP)?
Select a flight from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP) that takes off before 3 PM to reduce the likelihood of delays. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Islip from Tocumen Intl. Airport (PTY)?
John F. Kennedy Intl. Airport (JFK) is the only airport in Islip with direct flights from Tocumen Intl. Airport (PTY). Browse the available options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP) last-minute?
Waiting until right before your break to book a flight from PTY to ISP generally means paying more. While it's possible to find some last-minute discounts, they're not always guaranteed. Be flexible with your travel plans to maximize your chances of scoring a bargain.
Is it cheaper to book a PTY to ISP flight and hotel package?
You can save money by securing a PTY to ISP flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've selected your preferred accommodations and flights, consider adding extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to MacArthur Airport (ISP)?
In most cases, you can cancel or reschedule your PTY to ISP flight. However, additional charges may apply, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you need more details, visit our Customer Service portal.

Travel information

Origin airport
Tocumen Intl.
Destination airport
MacArthur
Roundtrip price
$1,414
Distance
2225 mi

Book with confidence

Panama City to Islip Flights

The cheapest times to fly from Panama City to Islip

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Islip are during the month of June. You can find some of the cheapest flights from Panama City to Islip with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Islip

Sunday is one of the best days to book for cheap flights from Panama City to Islip: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Islip

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Islip in 2026. You can also book with separate airlines for your outbound and return journeys, from $637 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Islip flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Islip airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Islip Flights

*Flight schedules are subject to change.

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*Available to One Key members.