$395 Cheap Flights from San Antonio (SAT) to La Crosse (LSE)

View $395 flight on Wed, Jan 7, 2026Opens in a new window

Popular airlines from San Antonio International Airport (SAT) to La Crosse, WI (LSE-La Crosse Municipal)

Cheap Flights from San Antonio to La Crosse (SAT-LSE)

Prices were available within the past 7 days and start at $395 for one-way flights and $442 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Mon, Dec 1 - Sun, Dec 7
SAT
San Antonio
LSE
La Crosse
$442 Roundtrip, found 2 days ago
$442
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Dec 1 from San Antonio to La Crosse, returning Sun, Dec 7, priced at $442 found 2 days ago
American Airlines
Mon, Nov 24 - Wed, Dec 3
SAT
San Antonio
LSE
La Crosse
$460 Roundtrip, found 1 day ago
$460
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Nov 24 from San Antonio to La Crosse, returning Wed, Dec 3, priced at $460 found 1 day ago
American Airlines
Thu, Nov 27 - Wed, Dec 3
SAT
San Antonio
LSE
La Crosse
$466 Roundtrip, found 1 day ago
$466
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Nov 27 from San Antonio to La Crosse, returning Wed, Dec 3, priced at $466 found 1 day ago
American Airlines
Wed, May 20 - Mon, May 25
SAT
San Antonio
LSE
La Crosse
$469 Roundtrip, found 5 days ago
$469
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, May 20 from San Antonio to La Crosse, returning Mon, May 25, priced at $469 found 5 days ago
American Airlines
Thu, Jan 1 - Wed, Jan 21
SAT
San Antonio
LSE
La Crosse
$470 Roundtrip, found 4 days ago
$470
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jan 1 from San Antonio to La Crosse, returning Wed, Jan 21, priced at $470 found 4 days ago
American Airlines
Sat, May 16 - Tue, Jun 2
SAT
San Antonio
LSE
La Crosse
$480 Roundtrip, found 4 days ago
$480
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, May 16 from San Antonio to La Crosse, returning Tue, Jun 2, priced at $480 found 4 days ago
American Airlines
Sat, May 23 - Wed, Jun 10
SAT
San Antonio
LSE
La Crosse
$485 Roundtrip, found 4 days ago
$485
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, May 23 from San Antonio to La Crosse, returning Wed, Jun 10, priced at $485 found 4 days ago
American Airlines
Tue, Nov 25 - Wed, Dec 3
SAT
San Antonio
LSE
La Crosse
$490 Roundtrip, found 1 day ago
$490
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Nov 25 from San Antonio to La Crosse, returning Wed, Dec 3, priced at $490 found 1 day ago
American Airlines
Tue, Dec 2 - Sun, Dec 7
SAT
San Antonio
LSE
La Crosse
$491 Roundtrip, found 2 days ago
$491
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Dec 2 from San Antonio to La Crosse, returning Sun, Dec 7, priced at $491 found 2 days ago
American Airlines
Sat, May 9 - Thu, May 28
SAT
San Antonio
LSE
La Crosse
$497 Roundtrip, found 4 days ago
$497
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, May 9 from San Antonio to La Crosse, returning Thu, May 28, priced at $497 found 4 days ago
American Airlines
Tue, May 19 - Tue, Jun 2
SAT
San Antonio
LSE
La Crosse
$500 Roundtrip, found 4 days ago
$500
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, May 19 from San Antonio to La Crosse, returning Tue, Jun 2, priced at $500 found 4 days ago
American Airlines
Thu, Jan 1 - Fri, Jan 16
SAT
San Antonio
LSE
La Crosse
$501 Roundtrip, found 4 days ago
$501
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jan 1 from San Antonio to La Crosse, returning Fri, Jan 16, priced at $501 found 4 days ago
American Airlines
Sat, May 23 - Tue, Jun 9
SAT
San Antonio
LSE
La Crosse
$505 Roundtrip, found 4 days ago
$505
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, May 23 from San Antonio to La Crosse, returning Tue, Jun 9, priced at $505 found 4 days ago
American Airlines
Sat, May 30 - Wed, Jun 17
SAT
San Antonio
LSE
La Crosse
$510 Roundtrip, found 4 days ago
$510
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, May 30 from San Antonio to La Crosse, returning Wed, Jun 17, priced at $510 found 4 days ago
American Airlines
Sat, Apr 25 - Thu, May 14
SAT
San Antonio
LSE
La Crosse
$511 Roundtrip, found 4 days ago
$511
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Apr 25 from San Antonio to La Crosse, returning Thu, May 14, priced at $511 found 4 days ago
American Airlines
Sat, May 23 - Thu, Jun 11
SAT
San Antonio
LSE
La Crosse
$516 Roundtrip, found 4 days ago
$516
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, May 23 from San Antonio to La Crosse, returning Thu, Jun 11, priced at $516 found 4 days ago

Alternative airports near La Crosse

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to La Crosse Municipal LSE. Cheapest and Closest option available. Average driving time to city center is 12 minutes. Flights from $529
LSE
La Crosse Municipal
CheapestClosest
Average driving time to city center12 min
Flights from $529

Frequently asked questions

How much does a flight from San Antonio Intl. Airport (SAT) to La Crosse Municipal Airport (LSE) cost?
Get a cheap one-way flight from $395 or cheap return flight from $442 from San Antonio Intl. Airport (SAT) to La Crosse Municipal Airport (LSE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from San Antonio Intl. Airport (SAT) to La Crosse Municipal Airport (LSE)?
Flying in December is a great way to save, as it's the cheapest month for flights between SAT and LSE. You'll usually find the lowest fares during the off-season.
What is the cheapest airline that flies from San Antonio Intl. Airport (SAT) to La Crosse Municipal Airport (LSE)?
To find the cheapest airline that'll fly you from SAT to LSE, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from San Antonio Intl. Airport (SAT) to La Crosse Municipal Airport (LSE)?
There aren't any daily nonstop flights from San Antonio Intl. Airport (SAT) to La Crosse Municipal Airport (LSE). But you can book flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way in no time.
What day of the week has the most flights from SAT to LSE?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary based on various factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Antonio Intl. Airport (SAT) to La Crosse Municipal Airport (LSE)?
Opt for a flight from San Antonio Intl. Airport (SAT) to La Crosse Municipal Airport (LSE) that takes off before 3 PM to reduce the likelihood of delays. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Antonio Intl. Airport (SAT) to La Crosse Municipal Airport (LSE) last-minute?
Booking your flight from SAT to LSE shortly before your getaway is generally more expensive. But if there's some wiggle room with your travel times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a SAT to LSE flight and hotel package?
You'll generally save money by securing a SAT to LSE flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After selecting your ideal accommodations and flights, you can add extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from San Antonio Intl. Airport (SAT) to La Crosse Municipal Airport (LSE)?
It's usually possible to reschedule or cancel your SAT to LSE flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
San Antonio Intl.
Destination airport
La Crosse Municipal
Airlines serving
American Airlines
Roundtrip price
$442
Distance
1067 mi

Book with confidence

San Antonio to La Crosse Flights

The cheapest times to fly from San Antonio to La Crosse

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Antonio to La Crosse are during the month of December. You can find some of the cheapest flights from San Antonio to La Crosse with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Antonio to La Crosse

Sunday is one of the best days to book for cheap flights from San Antonio to La Crosse: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Antonio to La Crosse

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Antonio to La Crosse in 2025. You can also book with separate airlines for your outbound and return journeys, from $395 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Antonio to La Crosse flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Antonio to La Crosse airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

San Antonio to La Crosse Flights

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*Available to One Key members.