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$135 Cheap Flights from Louisville (SDF) to Panama City (ECP)

View $135 flight on Mon, Oct 19, 2026Opens in a new window

Popular airlines from Louisville Intl. Airport (SDF) to Northwest Florida Beaches Intl. Airport (ECP)

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Cheap Flights from Louisville to Panama City (SDF-ECP)

Prices were available within the past 7 days and start at $135 for one-way flights and $284 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Mon, Oct 5 - Thu, Oct 8
SDF
Louisville
ECP
Panama City
$284 Roundtrip, found 2 days ago
$284
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Mon, Oct 5 from Louisville to Panama City, returning Thu, Oct 8, priced at $284 found 2 days ago
American Airlines
Mon, Oct 5 - Thu, Oct 8
SDF
Louisville
ECP
Panama City
$285 Roundtrip, found 2 days ago
$285
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Oct 5 from Louisville to Panama City, returning Thu, Oct 8, priced at $285 found 2 days ago
Southwest Airlines
Mon, Oct 5 - Thu, Oct 8
SDF
Louisville
ECP
Panama City
$288 Roundtrip, found 2 days ago
$288
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Mon, Oct 5 from Louisville to Panama City, returning Thu, Oct 8, priced at $288 found 2 days ago
Southwest Airlines
Tue, Sep 29 - Fri, Oct 2
SDF
Louisville
ECP
Panama City
$293 Roundtrip, found 2 days ago
$293
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Tue, Sep 29 from Louisville to Panama City, returning Fri, Oct 2, priced at $293 found 2 days ago
Southwest Airlines
Tue, Sep 29 - Fri, Oct 2
SDF
Louisville
ECP
Panama City
$298 Roundtrip, found 2 days ago
$298
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Tue, Sep 29 from Louisville to Panama City, returning Fri, Oct 2, priced at $298 found 2 days ago
Delta
Thu, Oct 15 - Tue, Oct 20
SDF
Louisville
ECP
Panama City
$309 Roundtrip, just found
$309
Roundtrip
just found
Select Delta flight, departing Thu, Oct 15 from Louisville to Panama City, returning Tue, Oct 20, priced at $309 just found
United
Sat, Oct 17 - Wed, Oct 21
SDF
Louisville
ECP
Panama City
$309 Roundtrip, found 8 hours ago
$309
Roundtrip
found 8 hours ago
Select United flight, departing Sat, Oct 17 from Louisville to Panama City, returning Wed, Oct 21, priced at $309 found 8 hours ago
American Airlines
Sat, Oct 17 - Wed, Oct 21
SDF
Louisville
ECP
Panama City
$309 Roundtrip, found 8 hours ago
$309
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Sat, Oct 17 from Louisville to Panama City, returning Wed, Oct 21, priced at $309 found 8 hours ago
United
Mon, Oct 5 - Sat, Oct 10
SDF
Louisville
ECP
Panama City
$313 Roundtrip, found 5 days ago
$313
Roundtrip
found 5 days ago
Select United flight, departing Mon, Oct 5 from Louisville to Panama City, returning Sat, Oct 10, priced at $313 found 5 days ago
Delta
Thu, Sep 17 - Sat, Sep 19
SDF
Louisville
ECP
Panama City
$314 Roundtrip, found 7 hours ago
$314
Roundtrip
found 7 hours ago
Select Delta flight, departing Thu, Sep 17 from Louisville to Panama City, returning Sat, Sep 19, priced at $314 found 7 hours ago

Find the cheapest month to fly from Louisville (SDF) to Panama City (ECP)

January is typically the cheapest month to fly

From $234 - $659 per traveler.

What you need to know for your flight from Louisville Intl. to Northwest Florida Beaches Intl.

Louisville (SDF) to Panama City (ECP) at a glance

Travel between Louisville (SDF) and Panama City (ECP) with a selection of airlines on this domestic short-haul route. Discover a range of options from full-service and budget carriers to secure the best itinerary that aligns with your travel plans, schedule, and budget. As you prepare to explore the iconic attractions and neighborhoods of Panama City, gather essential details for your flights from Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP).

  • Fastest flight duration: around 2h 30m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 500 miles (800 km)
  • Flights per week: around 10 departures on average
  • Typical fares (one-way): economy tickets often range from $120–$355, depending on seasonality and how far ahead you book

Flights from Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP)

According to recent traveler bookings, here are the top airlines favored for flights from Louisville to Panama City, usually featuring one-stop services. Popular layover points include Hartsfield-Jackson Atlanta International Airport (ATL) with approximately a 1h 15m layover, Charlotte-Douglas International Airport (CLT) at about 1h 45m, and O'Hare International Airport (ORD) with a 1h 15m layover. This allows travelers to customize their itineraries by balancing price, total travel time, and cabin class.

  • Delta: This full-service airline provides convenient one-stop service, with one-way ticket prices generally falling between $120 and $395. Delta represents about 64% of flights on this route, featuring a flight duration of 2 hours and 30 minutes, with the overall travel time being close to 4 hours, including layover.
  • American Airlines: As a full-service carrier, American Airlines offers one-stop service with one-way fares typically between $120 and $350. It makes up around 21% of departures for this route, with a flight time of 2 hours and 30 minutes, leading to an approximate total journey time of 4 hours, including layover.
  • Southwest Airlines: Known as a low-cost option, Southwest Airlines features one-stop service with one-way fares usually ranging from $120 to $345. This airline accounts for about 9% of the departures on this route, with an in-flight duration of 2 hours and 30 minutes and a total travel time of about 4 hours, factoring in layover.
  • United: United Airlines is another full-service carrier providing one-stop service, with one-way ticket prices that typically range from $130 to $380. It represents approximately 6% of flights on this route, offering a flying time of 2 hours and 30 minutes, and a total journey time of around 4 hours, including layover.

Travelers flying from Louisville to Panama City can opt for an upgrade, as Delta provides first-class service on this route.

Best time to fly from Louisville (SDF) to Panama City (ECP)

The most popular months for travelers flying from Louisville to Panama City are March, May, and June, when peak temperatures in Panama City reach up to 81.1°F in June. If you prefer quieter travel, consider January, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 54.1°F. For better deals, August usually offers the lowest average one-way fare around $195. Flight availability peaks in June, with approximately 13 flights per week, making it easier to find convenient departure times.

  • Cheapest time to fly: August usually offers good deals with average one-way fare around $195, roughly 12% cheaper than the yearly average.
  • More budget-friendly months to fly: July, June, and October typically offer average one-way fares of around $204.
  • Most flight options: June has the highest number of flights from Louisville to Panama City, with approximately 13 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January54.1°F (12.3°C)Low7$214
February57.9°F (14.4°C)Average8$218
March62.8°F (17.1°C)High9$268
April68.4°F (20.2°C)Average10$208
May75.0°F (23.9°C)High12$224
June81.1°F (27.3°C)High13$206
July82.6°F (28.1°C)Average11$201
August82.8°F (28.2°C)Average11$195
September79.5°F (26.4°C)Average11$209
October72.0°F (22.2°C)Average11$207
November62.4°F (16.9°C)Low8$255
December58.1°F (14.5°C)Low11$280

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Louisville (SDF) to Panama City (ECP)

  • Louisville to Fort Walton Beach (SDF-VPS): Northwest Florida Regional Airport (VPS) lies approximately 46 miles from Northwest Florida Beaches International Airport (ECP). One-way economy prices for this journey generally vary between $115 and $365, influenced by the season and advance booking time. This route is often served by one-stop flights, with common layover points at Hartsfield-Jackson Atlanta International Airport (ATL) and Charlotte-Douglas International Airport (CLT). Major airlines operating on this route include Delta and American Airlines, with first-class service also being offered.

How to find the best prices for flights from Louisville (SDF) to Panama City (ECP)

Getting some of the best deals on flights from Louisville to Panama City is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, which aligns with when most travelers make their reservations. Afternoon departures from 12pm to 6pm often offer lower prices, even though morning flights from 5am to 12pm are more popular. Additionally, flying on Tuesday typically provides cheaper options, while Saturday remains the most sought-after travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Northwest Florida Beaches International Airport from Louisville International Airport

Panama City welcomes travelers from Louisville with a range of transport options based on price, convenience, and proximity. Here's how to reach Panama City efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Panama City, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Northwest Florida Beaches International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Northwest Florida Beaches International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) cost?
You can find cheap one-way flights from $135 and cheap return flights from $284 Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) with Expedia. One-way flights typically cost between $173 and $628, and return flights often range between $326 and $969. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The cheapest month to fly from SDF to ECP is October when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
Enter SDF to ECP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Louisville Intl. (SDF) to Northwest Florida Beaches Intl. (ECP) with a layover in Midway Intl. (MDW), starting from around $232 for a round-trip ticket. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
To find a cheap flight from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The earliest flight from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) usually departs at around 5:00 AM, operated by American Airlines. This is a seasonal service active in March, and an early flight allows you to enjoy more of the beautiful beaches in Panama City. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
The most popular departure times for flights from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) are in the early morning, from 6am to 9am. About 46% of passengers prefer this time window. Many major carriers, including Delta, American Airlines, and United, offer flights during this window. This timing works well because it allows you to start your day early and arrive in Panama City with plenty of time to enjoy your destination.
How long does it take to fly from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
Flights from SDF to ECP with one stop typically take around 5 hours 30 minutes, covering approximately 541 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
You can fly first class between SDF and ECP. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight with Expedia?
It's easy to earn miles on a Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Panama City from Louisville Intl. (SDF)?
From Louisville Intl. (SDF), you can fly into Tocumen Intl. (PTY) and Northwest Florida Beaches Intl. (ECP) in Panama City. Some flights may connect through major hubs like Charlotte-Douglas Intl. (CLT), O'Hare Intl. (ORD), Washington Dulles Intl. (IAD) before reaching Panama City. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) at the last minute?
Typically, booking a last minute flight from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight and hotel package?
Securing a Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.)?
If you booked your Louisville, KY (SDF-Louisville Intl.) to Panama City, FL (ECP-Northwest Florida Beaches Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Louisville Intl.
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$283
Distance
541 mi

Book with confidence

Louisville to Panama City Flights

The cheapest times to fly from Louisville to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Louisville to Panama City are during the month of October. You can find some of the cheapest flights from Louisville to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Louisville to Panama City

Sunday is one of the best days to book for cheap flights from Louisville to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Louisville to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Louisville to Panama City in 2026. You can also book with separate airlines for your outbound and return journeys, from $135 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Louisville to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Louisville to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Louisville to Panama City Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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