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Cheap Flights from Santo Domingo to Panama City

Prices were available within the past 7 days and starts at $293 for one-way flights and $410 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Santo Domingo to Panama City route information

Origin Airport Las Americas Intl.
Destination Airport Tocumen Intl.
Airlines Serving Aeromexico, American Airlines, Avianca, Copa, Delta, Spirit Airlines
Flight Price $409
Distance 917 mi

Cheap SDQ to PTY Flights

  • From Santo Domingo to Panama City, which day of the week is going to have the most flight times?

    When you're flying from SDQ to PTY, the day with the most flight times is Thursday, with 10 different options. The day of the week with the fewest number of times is Sunday with only five options.
  • How long do most people visit Panama City?

    Of course, you're not most people, but if you were, you'd stay roughly 12 days.
  • Can I change the date of my flight?

    You sure can adjust your departure date and you may save by doing it. The lowest-cost day to fly in March is Sunday. Being flexible with your travel days can provide you extra savings when booking.
  • How long is the flight from SDQ to PTY?

    Copa Airlines can get you there in two hours and 36 minutes. So, if you were to leave Santo Domingo at 5:41 PM AST, you would arrive in Panama City at 7:17 PM EST. Giving you enough time if you want to catch up on your reading before your plane touches down (don't forget, there is a one-hour time difference).
  • How long does it take to fly from Santo Domingo to Panama City?

    If you're able to take the direct flight (which is offered by Copa Airlines), you will be able to leave SDQ at 5:41 PM AST and get to PTY at 7:17 PM EST (two hours and 36 minutes). Remember, there is a time change of one hour.
  • How many flights are there per day from Santo Domingo to Panama City?

    Depending on the day of the week, the number of flight times will change, but on average there are eight. You'll have more options on this route than most others departing DO.
  • What is the cheapest day to fly to Panama City?

    As of Feb 17th, the best day for booking to Panama City (PTY) is Mar 4th. Your ticket will cost $475, which is 7% less than the average price to book the same route.

Santo Domingo to Panama City Flights

Whether you’re looking for a grand adventure or just want to get away for a last-minute break, flights from Santo Domingo to Panama City offer the perfect respite. Not only does exploring Panama City provide the chance to make some magical memories, dip into delectable dishes, and tour the local landmarks, but the cheap airfare means you won’t bust your budget. So no matter whether your ideal itinerary involves flying one way, non-stop, or round trip, you’re bound to find flights that match your schedule on Expedia, and at prices that won’t shock your wallet.

Bagging a cheap flight from Santo Domingo to Tocumen may mean more dollars to spend on for one-of-a-kind souvenirs when you arrive, but it doesn’t mean you have to skimp on your travel experience, as Expedia offers a sizzling selection of cheap airlines that’ll put you in your happy place on their planes, whether that’s getting lost in a hair-raising airport thriller, dreaming on the passing landscape over a glass of bubbly, or jotting down your vacation bucket list at 38,000 feet. There’s also bound to be plenty of opportunities to snap a few photos of the high life that will make your friends green with envy. After all, enjoying the journey is part of the fun.

With so many affordable flights and so many wonderful adventures awaiting you, there’s no reason to put off booking a fantastic flight from SDQ to PTY today. So don’t leave it to the last minute to make your dream trip a reality: pack your bags with your go-to travel accessories, put together your list of must-see attractions and can’t-miss activities, and get ready to broaden your horizons – with Expedia, the wonders of Panama City are only a plane trip away. Book your travel arrangements with us today!

If you would like to book flights to Panama City more flexbily many prefers to purchase one-way tickets with options to take different airlines. One way ticket to Tocumen is $293 now!

Feb 12, 2020

The crew was awesome and extremely nice

Dec 30, 2019

The best!

Dec 27, 2019


Oct 8, 2019


May 17, 2019

Really enjoy flying with Copa. Love it!

Mar 6, 2019

Copa....WOW! I enjoyed my experience flying on your planes, interacting with your staff...what an upgrade from my past experiences with other airlines. I will fly Copa in the future...amazing company!

Dec 29, 2018


Dec 11, 2018

Staff, very nice and helpful at counter and on board. Many thanks!

Oct 24, 2018

the panama airport security procedures were not ok at all. took stuff from peoples bans at random (not tsa related). corralled us in weird area for more than an hour with no access to food, water, or bathrooms before boarding.

Sep 29, 2018

It was my family and my first time flying on COPA and we were very pleased with the great customer service! Thank you COPA for thiniking of your customers!!!

Package Disclaimer

*Savings amount equal to 100% when flight + hotel are booked together. Prices based on searches conducted by fellow shoppers within the past 24 hours. There is no guarantee that these prices will be in effect at the time of your search. Vacation package savings are based on comparison to prices on of the same components booked separately. Savings vary based on origin/destination, length of trip, stay dates and travel partners, and aren't available on all packages.