$491 Cheap Flights from San Francisco (SFO) to Samos (SMI)

View $491 flight on Tue, Apr 28, 2026Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to Samos (SMI-Samos Intl.)

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Cheap Flights from San Francisco to Samos (SFO-SMI)

Prices were available within the past 7 days and start at $491 for one-way flights and $1,239 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Brussels Airlines
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$1,239 Roundtrip, found 5 days ago
$1,239
Roundtrip
found 5 days ago
Select Brussels Airlines flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $1,239 found 5 days ago
Air Canada
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$1,454 Roundtrip, found 5 days ago
$1,454
Roundtrip
found 5 days ago
Select Air Canada flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $1,454 found 5 days ago
Air Canada
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$1,653 Roundtrip, found 5 days ago
$1,653
Roundtrip
found 5 days ago
Select Air Canada flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $1,653 found 5 days ago
Air Canada
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$1,804 Roundtrip, found 5 days ago
$1,804
Roundtrip
found 5 days ago
Select Air Canada flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $1,804 found 5 days ago
Emirates
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$1,828 Roundtrip, found 5 days ago
$1,828
Roundtrip
found 5 days ago
Select Emirates flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $1,828 found 5 days ago
Brussels Airlines
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$2,182 Roundtrip, found 5 days ago
$2,182
Roundtrip
found 5 days ago
Select Brussels Airlines flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $2,182 found 5 days ago
Emirates
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$2,268 Roundtrip, found 5 days ago
$2,268
Roundtrip
found 5 days ago
Select Emirates flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $2,268 found 5 days ago
Brussels Airlines
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$2,337 Roundtrip, found 5 days ago
$2,337
Roundtrip
found 5 days ago
Select Brussels Airlines flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $2,337 found 5 days ago
Air Canada
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$2,409 Roundtrip, found 5 days ago
$2,409
Roundtrip
found 5 days ago
Select Air Canada flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $2,409 found 5 days ago
Air Canada
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$2,508 Roundtrip, found 5 days ago
$2,508
Roundtrip
found 5 days ago
Select Air Canada flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $2,508 found 5 days ago
Brussels Airlines
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$2,537 Roundtrip, found 5 days ago
$2,537
Roundtrip
found 5 days ago
Select Brussels Airlines flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $2,537 found 5 days ago
Air Canada
Tue, Apr 28 - Wed, May 27
SFO
San Francisco
SMI
Samos
$2,684 Roundtrip, found 5 days ago
$2,684
Roundtrip
found 5 days ago
Select Air Canada flight, departing Tue, Apr 28 from San Francisco to Samos, returning Wed, May 27, priced at $2,684 found 5 days ago

Frequently asked questions

How much does a flight from San Francisco Intl. Airport (SFO) to Samos Intl. Airport (SMI) cost?
Snag a cheap one-way flight from $491 or cheap return flight from $1,239 from San Francisco Intl. Airport (SFO) to Samos Intl. Airport (SMI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from San Francisco Intl. Airport (SFO) to Samos Intl. Airport (SMI)?
The cheapest month to fly from SFO to SMI is April, when there's less demand. Off-peak months are often when better flight deals are available between these airports.
What is the cheapest airline that flies from San Francisco Intl. Airport (SFO) to Samos Intl. Airport (SMI)?
To find the cheapest airline that'll fly you from SFO to SMI, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from San Francisco Intl. Airport (SFO) to Samos Intl. Airport (SMI)?
You'll have to hop on a flight with a layover when traveling from San Francisco Intl. Airport (SFO) to Samos Intl. Airport (SMI). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from SFO to SMI?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Francisco Intl. Airport (SFO) to Samos Intl. Airport (SMI)?
To arrive at Samos Intl. Airport (SMI) without delays, opt for a flight that takes off from San Francisco Intl. Airport (SFO) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Francisco Intl. Airport (SFO) to Samos Intl. Airport (SMI) last-minute?
Last-minute fares from SFO to SMI are usually more expensive. To lock in the best rates, start searching for flights well in advance. That being said, if you can play around with your travel dates, it's possible to land a cheap ticket just before your departure.
Is it cheaper to book a SFO to SMI flight and hotel package?
You can save money by booking a SFO to SMI flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After choosing your preferred flights and accommodations, consider adding extras including tours, car rentals and activities.
Can I cancel or change the date of my flight from San Francisco Intl. Airport (SFO) to Samos Intl. Airport (SMI)?
In most instances, you can cancel or reschedule your SFO to SMI flight. However, there may be additional charges, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you'd like more information, visit our Customer Service portal.

Travel information

Origin airport
San Francisco Intl.
Destination airport
Samos Intl.
Roundtrip price
$1,238
Distance
6877 mi

Book with confidence

San Francisco to Samos Flights

The cheapest times to fly from San Francisco to Samos

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Francisco to Samos are during the month of April. You can find some of the cheapest flights from San Francisco to Samos with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Francisco to Samos

Sunday is one of the best days to book for cheap flights from San Francisco to Samos: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Francisco to Samos

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Francisco to Samos in 2025. You can also book with separate airlines for your outbound and return journeys, from $491 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Francisco to Samos flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Francisco to Samos airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

San Francisco to Samos Flights

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