A vintage sign for Fresno, stating "The Best Little City in the U.S.A. on Van Ness Ave."

$187 Cheap Flights from Knoxville (TYS) to Fresno (FAT)

View $187 flight on Thu, Dec 17, 2026Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to Fresno Yosemite Intl. Airport (FAT)

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Cheap Flights from Knoxville to Fresno (TYS-FAT)

Prices were available within the past 7 days and start at $187 for one-way flights and $377 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Jan 6 - Thu, Jan 7
TYS
Knoxville
FAT
Fresno
$377 Roundtrip, found 4 days ago
$377
Roundtrip
found 4 days ago
Select United flight, departing Wed, Jan 6 from Knoxville to Fresno, returning Thu, Jan 7, priced at $377 found 4 days ago
United
Wed, Oct 21 - Sat, Oct 24
TYS
Knoxville
FAT
Fresno
$397 Roundtrip, found 2 days ago
$397
Roundtrip
found 2 days ago
Select United flight, departing Wed, Oct 21 from Knoxville to Fresno, returning Sat, Oct 24, priced at $397 found 2 days ago
United
Tue, Nov 3 - Mon, Nov 9
TYS
Knoxville
FAT
Fresno
$400 Roundtrip, found 2 days ago
$400
Roundtrip
found 2 days ago
Select United flight, departing Tue, Nov 3 from Knoxville to Fresno, returning Mon, Nov 9, priced at $400 found 2 days ago
United
Wed, Jan 6 - Tue, Mar 9
TYS
Knoxville
FAT
Fresno
$409 Roundtrip, found 4 days ago
$409
Roundtrip
found 4 days ago
Select United flight, departing Wed, Jan 6 from Knoxville to Fresno, returning Tue, Mar 9, priced at $409 found 4 days ago
American Airlines
Wed, Dec 9 - Sun, Dec 13
TYS
Knoxville
FAT
Fresno
$415 Roundtrip, found 2 days ago
$415
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Dec 9 from Knoxville to Fresno, returning Sun, Dec 13, priced at $415 found 2 days ago
United
Tue, Jan 5 - Tue, Mar 9
TYS
Knoxville
FAT
Fresno
$416 Roundtrip, found 4 days ago
$416
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jan 5 from Knoxville to Fresno, returning Tue, Mar 9, priced at $416 found 4 days ago
United
Wed, Oct 21 - Wed, Oct 28
TYS
Knoxville
FAT
Fresno
$417 Roundtrip, found 11 hours ago
$417
Roundtrip
found 11 hours ago
Select United flight, departing Wed, Oct 21 from Knoxville to Fresno, returning Wed, Oct 28, priced at $417 found 11 hours ago
Southwest Airlines
Tue, Dec 22 - Wed, Dec 30
TYS
Knoxville
FAT
Fresno
$418 Roundtrip, found 4 days ago
$418
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Tue, Dec 22 from Knoxville to Fresno, returning Wed, Dec 30, priced at $418 found 4 days ago
Delta
Wed, Nov 4 - Tue, Nov 10
TYS
Knoxville
FAT
Fresno
$427 Roundtrip, found 11 hours ago
$427
Roundtrip
found 11 hours ago
Select Delta flight, departing Wed, Nov 4 from Knoxville to Fresno, returning Tue, Nov 10, priced at $427 found 11 hours ago
Alaska Airlines
Tue, Oct 20 - Tue, Oct 27
TYS
Knoxville
FAT
Fresno
$644 Roundtrip, found 20 hours ago
$644
Roundtrip
found 20 hours ago
Select Alaska Airlines flight, departing Tue, Oct 20 from Knoxville to Fresno, returning Tue, Oct 27, priced at $644 found 20 hours ago

Alternative airports near Fresno

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Fresno Yosemite Intl. FAT. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $508
FAT
Fresno Yosemite Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $508

What you need to know for your flight from McGhee Tyson to Fresno Yosemite Intl.

Knoxville (TYS) to Fresno (FAT) at a glance

Explore a variety of Fresno flights from Knoxville (TYS) to Fresno Yosemite International Airport (FAT) on this domestic short-haul route. You can choose from both full-service and low-cost carriers, allowing you to find the best itinerary that aligns with your budget and travel plans. With weekly flights available, you’ll have the flexibility to experience Fresno's renowned attractions and neighborhoods. Check out the essential details for flights from McGhee Tyson Airport to help plan your journey.

  • Fastest flight duration: around 6 hours in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 2,000 miles (3,220 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $145–$445, depending on seasonality and how far ahead you book

Flights from McGhee Tyson Airport (TYS) to Fresno Yosemite International Airport (FAT)

According to recent traveler bookings, here are the top airlines favored for flights from Knoxville to Fresno, particularly for one-stop and multi-stop journeys. Common layover points include Dallas-Fort Worth International Airport (DFW) with an average layover of about 1 hour and 15 minutes, Denver International Airport (DEN) also around 1 hour and 15 minutes, and Hartsfield-Jackson Atlanta International Airport (ATL) with a layover of approximately 2 hours and 45 minutes. This variety allows you to consider different combinations of price, total travel time, and cabin class to secure the best itinerary.

  • American Airlines: As a comprehensive carrier, American Airlines provides one-stop flights with one-way ticket prices generally falling between $145 and $415. This airline operates about 67% of departures on this route, featuring an in-flight duration of 6 hours and a total travel time of about 7 hours and 30 minutes, including a layover.
  • United: Offering both one-stop and multi-stop options, United is a full-service airline with typical one-way fares ranging from $175 to $535. It represents roughly 24% of departures along this route, with a standard flight time of 6 hours and an overall journey time of around 7 hours and 30 minutes.
  • Delta: Delta is another full-service option providing one-stop services, with one-way fares usually between $170 and $455. It accounts for about 8% of flights on this route, featuring an in-flight duration of 6 hours and a total travel time close to 7 hours and 30 minutes, including layover time.

Best time to fly from Knoxville (TYS) to Fresno (FAT)

The most popular months for travelers flying from Knoxville to Fresno are April, May, and July, when peak temperatures in Fresno reach up to 86°F in July. If you prefer quieter travel, consider October, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 67.6°F. For better deals, January usually offers the lowest average one-way fare around $223. Flight availability peaks in May, with approximately 10 flights per week, making it easier to find convenient departure times. January, April, and August have the fewest flights, with approximately 7 flights per week.

  • Cheapest time to fly: January usually offers good deals with average one-way fare around $223, roughly 22% cheaper than the yearly average.
  • Most flight options: May has the highest number of flights from Knoxville to Fresno, with approximately 10 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January49.5°F (9.7°C)Average7$223
February50.9°F (10.5°C)Average9$261
March55.4°F (13.0°C)Average8$311
April62.1°F (16.7°C)High7$304
May70.0°F (21.1°C)High10$263
June79.5°F (26.4°C)Low8$326
July86.0°F (30.0°C)High8$270
August84.4°F (29.1°C)Average7$298
September78.8°F (26.0°C)Average9$266
October67.6°F (19.8°C)Low8$279
November55.9°F (13.3°C)Low8$288
December48.7°F (9.3°C)Average8$376

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Knoxville (TYS) to Fresno (FAT)

  • Chattanooga to Fresno (CHA-FAT): Chattanooga Metropolitan Airport (CHA) is located approximately 86 miles from McGhee Tyson Airport (TYS). One-way fares in economy class for this journey generally fall between $145 and $485, influenced by the season and the timing of your reservation. Typically, this route is offered with one-stop flights, featuring popular layover points at Dallas-Fort Worth International Airport (DFW) and Hartsfield-Jackson Atlanta International Airport (ATL). The main airlines operating on this route include American Airlines and Delta, with first-class service also available.

How to find the best prices for flights from Knoxville (TYS) to Fresno (FAT)

Getting some of the best deals on flights from Knoxville to Fresno is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking at least two months in advance, although most travelers tend to book 2-8 weeks ahead. Evening departures from 6 PM to midnight often offer lower prices, while afternoon flights from 12 PM to 6 PM are the most popular. Additionally, flying on Tuesday generally yields cheaper rates, but Wednesday is the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Fresno Yosemite International Airport from McGhee Tyson Airport

Fresno welcomes travelers from Knoxville with a range of transport options based on price, convenience, and proximity. For departures, McGhee Tyson Airport is roughly a 20-minute drive (covering about 15 miles) from central Knoxville. Here's how to reach Fresno efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Fresno, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Fresno Yosemite International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Fresno Yosemite International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Fresno Yosemite International Airport, Fresno Station, a train station, is located about 5.6 miles away by car, providing convenient access to rail services for travelers.

Frequently asked questions

How much does a flight from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.) cost?
You can find cheap one-way flights from $187 and cheap return flights from $377 Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.) with Expedia. One-way flights generally range between $222 and $1141, and roundtrip flights usually range from $481 to $1516. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.)?
September is the cheapest month to fly from Knoxville (TYS) to Fresno (FAT), with average return fares around $419. This price is about 20% lower than the average throughout the year, likely due to reduced travel demand after the summer. Other budget-friendly months for this route include April and August.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.)?
Enter TYS to FAT and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Knoxville (TYS) to Fresno (FAT), with round-trip tickets starting from around $365 with a layover in Nashville (BNA). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.)?
To find a cheap flight from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.)?
For flights from Knoxville (TYS) to Fresno (FAT), September and April are the ideal months to consider. You can find return flights at an average price of about $419 during these times. September is perfect for enjoying the late summer weather, while April offers a refreshing spring atmosphere.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.)?
The earliest flight from McGhee Tyson (TYS) to Fresno Yosemite International (FAT) typically departs at around 5:00 AM, operated by American Airlines. This is a seasonal service active in December, and an early departure can help you make the most of your time in Fresno. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
How long does it take to fly from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.)?
Flights from TYS to FAT with one stop typically take around 7 hours 50 minutes, covering approximately 1,980 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.)?
First class seats are offered on the TYS to FAT route. First class cabins are available on:

  • American Airlines
  • United Airlines
  • Delta Air Lines

How do I earn miles on a Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.) flight with Expedia?
It's easy to earn miles on a Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Fresno from McGhee Tyson (TYS)?
If you're planning to travel to Fresno from McGhee Tyson (TYS), you can fly into Fresno Yosemite Intl. (FAT) Some flights may connect through major hubs like O'Hare Intl. (ORD), Charlotte-Douglas Intl. (CLT), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Fresno. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.) at the last minute?
Typically, booking a last minute flight from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.) flight and hotel package?
Securing a Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.) Fresno Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.)?
If you booked your Knoxville, TN (TYS-McGhee Tyson) to Fresno, CA (FAT-Fresno Yosemite Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
McGhee Tyson
Destination airport
Fresno Yosemite Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$376
Distance
1979 mi

Book with confidence

Knoxville to Fresno Flights

The cheapest times to fly from Knoxville to Fresno

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Fresno are during the month of January. You can find some of the cheapest flights from Knoxville to Fresno with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Fresno

Sunday is one of the best days to book for cheap flights from Knoxville to Fresno: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Fresno

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Fresno in 2026. You can also book with separate airlines for your outbound and return journeys, from $187 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Fresno flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Fresno airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Fresno Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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