$55 Cheap Flights from Knoxville (TYS) to Minneapolis (MSP)

View $55 flight on Mon, Dec 8, 2025Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)

Cheap Flights from Knoxville to Minneapolis (TYS-MSP)

Prices were available within the past 7 days and start at $55 for one-way flights and $120 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Mon, Dec 8 - Mon, Dec 15
TYS
Knoxville
MSP
Minneapolis
$120 Roundtrip, found 2 days ago
$120
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Dec 8 from Knoxville to Minneapolis, returning Mon, Dec 15, priced at $120 found 2 days ago
Frontier Airlines
Thu, Dec 11 - Sun, Dec 14
TYS
Knoxville
MSP
Minneapolis
$124 Roundtrip, found 11 hours ago
$124
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Thu, Dec 11 from Knoxville to Minneapolis, returning Sun, Dec 14, priced at $124 found 11 hours ago
Frontier Airlines
Thu, Dec 11 - Mon, Dec 15
TYS
Knoxville
MSP
Minneapolis
$127 Roundtrip, found 2 days ago
$127
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Dec 11 from Knoxville to Minneapolis, returning Mon, Dec 15, priced at $127 found 2 days ago
Frontier Airlines
Thu, Dec 11 - Sun, Dec 14
TYS
Knoxville
MSP
Minneapolis
$128 Roundtrip, found 11 hours ago
$128
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Thu, Dec 11 from Knoxville to Minneapolis, returning Sun, Dec 14, priced at $128 found 11 hours ago
Frontier Airlines
Mon, Dec 8 - Sun, Dec 14
TYS
Knoxville
MSP
Minneapolis
$134 Roundtrip, found 2 days ago
$134
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Dec 8 from Knoxville to Minneapolis, returning Sun, Dec 14, priced at $134 found 2 days ago
Frontier Airlines
Thu, Nov 13 - Thu, Dec 4
TYS
Knoxville
MSP
Minneapolis
$140 Roundtrip, found 4 days ago
$140
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Nov 13 from Knoxville to Minneapolis, returning Thu, Dec 4, priced at $140 found 4 days ago
American Airlines
Thu, Dec 4 - Sun, Dec 7
TYS
Knoxville
MSP
Minneapolis
$297 Roundtrip, found 2 days ago
$297
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Dec 4 from Knoxville to Minneapolis, returning Sun, Dec 7, priced at $297 found 2 days ago
Delta
Thu, Feb 12 - Mon, Feb 16
TYS
Knoxville
MSP
Minneapolis
$299 Roundtrip, found 5 hours ago
$299
Roundtrip
found 5 hours ago
Select Delta flight, departing Thu, Feb 12 from Knoxville to Minneapolis, returning Mon, Feb 16, priced at $299 found 5 hours ago
United
Fri, Dec 5 - Mon, Dec 8
TYS
Knoxville
MSP
Minneapolis
$319 Roundtrip, found 5 hours ago
$319
Roundtrip
found 5 hours ago
Select United flight, departing Fri, Dec 5 from Knoxville to Minneapolis, returning Mon, Dec 8, priced at $319 found 5 hours ago
Southwest Airlines
Wed, Mar 25 - Wed, Apr 1
TYS
Knoxville
MSP
Minneapolis
$319 Roundtrip, found 5 days ago
$319
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Mar 25 from Knoxville to Minneapolis, returning Wed, Apr 1, priced at $319 found 5 days ago

Find the cheapest month to fly from Knoxville (TYS) to Minneapolis (MSP)

January is typically the cheapest month to fly

From $140 - $659 per traveler.

Alternative airports near Minneapolis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Minneapolis - St. Paul Intl. MSP. Cheapest and Closest option available. Average driving time to city center is 12 minutes. Flights from $489
MSP
Minneapolis - St. Paul Intl.
CheapestClosest
Average driving time to city center12 min
Flights from $489

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP) cost?
Snag a cheap one-way flight from $55 or cheap return flight from $120 from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
Traveling in December may help you find better deals, as it's the cheapest month for flights between TYS and MSP. You'll typically find the lowest prices during the off-season.
Which airlines fly direct from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
When flying out of McGhee Tyson Airport (TYS), you can get on a nonstop flight to Minneapolis - St. Paul Intl. Airport (MSP) with Delta Air Lines.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
To find the cheapest airline flying from TYS to MSP, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
On average, you can pick from 6 direct flights per week from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP). For more options, consider flights with layovers. Just enter your dates on Expedia and then filter your search to show one or more stops.
What are the most popular departure times for flights from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
Flights between TYS and MSP are their busiest at 6 AM. If you want a quieter trip and potentially cheaper tickets, look for a time when demand is lower.
What day of the week has the most flights from TYS to MSP?
If you jet off on a Friday, you'll get the largest range of options for flights from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP).
What is the earliest flight from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
The earliest flight out of McGhee Tyson Airport (TYS) is at around 6:36AM UTC-5. Board this flight and you'll land at Minneapolis - St. Paul Intl. Airport (MSP) at approximately 8:12AM UTC-6. The overall travel time is 2h 36m.
How long does it take to fly from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
It takes about 2 hours and 36 minutes to cover the 790 mi from TYS to MSP.
What airline has the least delays from TYS to MSP?
Delta Air Lines has the best track record for on-time direct flights from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP), with an on-time rating of 80%. Use the Expedia App to view your journey status before you head off and receive notifications about any trip changes.
What is the best time to fly from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
To avoid possible delays on the McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP) route, fly before 3 PM. Later departures are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Minneapolis - St. Paul from McGhee Tyson Airport (TYS)?
Check out your flight options from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP). This is the only Minneapolis - St. Paul airport you can arrive at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP) last-minute?
Booking your plane ticket from TYS to MSP right before your journey is usually more expensive. However, if there's some wiggle room with your itinerary, you could score a cheap last-minute fare.
Is it cheaper to book a TYS to MSP flight and hotel package?
You'll typically save money by securing a TYS to MSP flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. Once you've selected your ideal accommodations and flights, consider adding extras including activities, car rentals and tours.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
In most instances, you can reschedule or cancel your TYS to MSP flight. However, additional fees may apply, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you'd like more details, visit our Customer Service portal.

Travel information

Origin airport
McGhee Tyson
Destination airport
Minneapolis - St. Paul Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$120
Distance
792 mi
Average flight time
1 hour 31 mins

Book with confidence

Knoxville to Minneapolis Flights

The cheapest times to fly from Knoxville to Minneapolis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Minneapolis are during the month of December. You can find some of the cheapest flights from Knoxville to Minneapolis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Minneapolis

Sunday is one of the best days to book for cheap flights from Knoxville to Minneapolis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Minneapolis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Minneapolis in 2025. You can also book with separate airlines for your outbound and return journeys, from $55 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Minneapolis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Minneapolis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Minneapolis Flights

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*Available to One Key members.