---
title: "Southeast Missouri Pet-friendly Vacations 2026 | Expedia"
description: "Find incredible offers on Southeast Missouri Pet-friendly Vacations! Plan your next Pet-friendly trip today with Expedia."
canonical: "https://www.expedia.com/lp/theme-vacations/pet-friendly-vacations/6058763/Southeast-Missouri"
language: en-US
market: US
currency: USD
prices_as_of: 2026-11-13T22:08:03Z
---

![A group of men in red uniforms with gold accents, holding rifles and wearing kilts.](https://images.trvl-media.com/place/148078/1ef720df-0786-4e45-8a4f-890d982b757b.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

Photo by JG Morris

# Southeast Missouri Pet-friendly Vacations

## Book a Hotel + Flight or Car together to unlock savings

- ## Plan, book, travel with confidence
- ### Better together
Save up to $2,000 when you book a flight and hotel together\*
- ### Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
- ### Rest easy
Plan, book, and manage your trip all in one place

## Discover the most popular places to visit in Southeast Missouri

![A large, reddish-brown rock formation with a smooth, rounded surface and a unique, intertwined shape.](https://images.trvl-media.com/place/6058764/b46f1ef8-a151-4a6d-a0ba-117f21235d8d.jpg?impolicy=fcrop&w=960&h=640&p=1&q=medium)

Photo by Pat Long

### Elephant Rocks State Park

Rating: 9.6/10 (98 reviews)

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&amenities=PETS&regionId=553248621532648464)

### Southeast Missouri State University
![A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.](https://images.trvl-media.com/place/553248621554122994/3bc9a5e0-c92b-4ca4-b94a-564376156913.jpg?impolicy=fcrop&w=960&h=640&p=1&q=medium)

Rating: 8.8/10 (248 reviews)

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&amenities=PETS&regionId=553248621554122994)

![A sunset over a lake with boats and ducks.](https://images.trvl-media.com/place/183505/9493e565-66da-46c4-8222-30a8f5da22bb.jpg?impolicy=fcrop&w=960&h=640&p=1&q=medium)

Photo by JG Morris

### Lake Wappapello

Rating: 8.8/10 (54 reviews)

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&amenities=PETS&regionId=553248621532648460)

### Century Casino & Hotel Cape Girardeau

Rating: 8.4/10 (176 reviews)

Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&amenities=PETS&regionId=553248621532655780)

### Century Casino Caruthersville

Rating: 7.0/10 (57 reviews)

Why not roll the dice with a visit to Century Casino Caruthersville during your travels in Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

[See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests&amenities=PETS&regionId=553248621532655201)

### What to do in Southeast Missouri

![Pythian Castle](https://mediaim.expedia.com/localexpert/1103662/fba75008-24ca-4fd0-97a7-d7e7e96fc4e5.jpg?impolicy=resizecrop&rw=1005&rh=565)

#### [Night Ghost Tour of Pythian Castle in Springfield Missouri](https://www.expedia.com/things-to-do/a.a1103662.activity-details?rid=6058763)

$20

per adult

96% of travelers recommend

[See all activities in Southeast Missouri](https://www.expedia.com/things-to-do/search?rid=6058763)

## Top Pet-friendly Southeast Missouri Hotels

### [Madison Inn Lodge](https://www.expedia.com/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information)

![A spacious kitchen with a dining area, featuring a ceiling fan, a TV mounted on the wall, and a large rug in the center.](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/765df2ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 730 Plaza Drive, Fredericktown, MO, 63645, US
- Location: 24.2 mi from Southeast Missouri
- Star rating: 2.5/5
- Guest rating: 7.6/10 (Good, 314 reviews)
- Price: $87 nightly, $95 total, Nov 15 - Nov 16, Total with taxes and fees, for Top Pet-friendly Southeast Missouri Hotels
- Review: Room was very clean . The bathroom wall had been repaired and it was done sloppy . Roughly patched and paint on floor . Staff was super friendly

### [Hampton Inn & Suites By Hilton Festus](https://www.expedia.com/Festus-Hotels-Hampton-Inn-Suites-By-Hilton-Festus.h133189319.Hotel-Information)

![A hotel room with a bed, bedside tables, a desk, a chair, a lamp, and a window.](https://images.trvl-media.com/lodging/134000000/133190000/133189400/133189319/1c91d48c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

- Location: 67.8 mi from Southeast Missouri
- Guest rating: 9.4/10 (Exceptional, 29 reviews)
- Price: $114 nightly, $130 total, Nov 22 - Nov 23, Total with taxes and fees, for Top Pet-friendly Southeast Missouri Hotels
- Review: Good location, updated hotel!

### [Drury Inn & Suites Poplar Bluff](https://www.expedia.com/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information)

![An indoor swimming pool with a clear view of the outside through large windows.](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/239bd50a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 2220 N Westwood Blvd, Poplar Bluff, MO, 63901, US
- Location: 30.7 mi from Southeast Missouri
- Star rating: 3/5
- Guest rating: 9.4/10 (Exceptional, 1002 reviews)
- Price: $94 nightly, $106 total, Nov 19 - Nov 20, Total with taxes and fees, for Top Pet-friendly Southeast Missouri Hotels
- Review: I like how clean they were, and the food was excellent and the hot tub was great

### [Hampton Inn Poplar Bluff](https://www.expedia.com/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information)

![A Hampton Inn hotel with a brick facade, multiple windows, and a well-lit entrance.](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/w5755h3835x5y5-3c122b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 2420 Crestwood Dr, Poplar Bluff, MO, 63901, US
- Location: 30.4 mi from Southeast Missouri
- Star rating: 2.5/5
- Guest rating: 9.4/10 (Exceptional, 1022 reviews)
- Price: $89 nightly, $100 total, Dec 6 - Dec 7, Total with taxes and fees, for Top Pet-friendly Southeast Missouri Hotels

### [Holiday Inn Poplar Bluff by IHG](https://www.expedia.com/Poplar-Bluff-Hotels-Holiday-Inn-Poplar-Bluff.h1222183.Hotel-Information)

![A Holiday Inn hotel with a covered entrance, multiple floors, and a parking lot.](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/2f14001b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 2781 N Westwood Blvd, Poplar Bluff, MO, 63901, US
- Location: 30.2 mi from Southeast Missouri
- Star rating: 3/5
- Guest rating: 8.8/10 (Excellent, 807 reviews)
- Price: $75 nightly, $85 total, Dec 13 - Dec 14, Total with taxes and fees, for Top Pet-friendly Southeast Missouri Hotels

### [Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy](https://www.expedia.com/French-Village-Hotels-Postcard-Cabins-St-Francois.h110550817.Hotel-Information)

![A cabin surrounded by a natural forest setting with a fire pit and outdoor seating.](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/bf5cb79e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 7555 State Hwy Y, French Village, MO, 63627, US
- Location: 51.5 mi from Southeast Missouri
- Star rating: 2/5
- Guest rating: 10/10 (Exceptional, 121 reviews)
- Price: $128 nightly, $145 total, Dec 14 - Dec 15, Total with taxes and fees, for Top Pet-friendly Southeast Missouri Hotels

### [Super 8 by Wyndham Perryville](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information)

![A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/ef8850d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 1119 Vincent Dr, Perryville, MO, 63775, US
- Location: 44.5 mi from Southeast Missouri
- Star rating: 2/5
- Guest rating: 8.6/10 (Excellent, 1000 reviews)
- Price: $65 nightly, $75 total, Nov 29 - Nov 30, Total with taxes and fees, for Top Pet-friendly Southeast Missouri Hotels

### [Tru By Hilton Cape Girardeau](https://www.expedia.com/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

![A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/bcbeb569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 2520 Veterans Memorial Dr, Cape Girardeau, MO, 63701, US
- Location: 46.4 mi from Southeast Missouri
- Star rating: 2.5/5
- Guest rating: 9.6/10 (Exceptional, 201 reviews)
- Price: $85 nightly, $97 total, Nov 22 - Nov 23, Total with taxes and fees, for Top Pet-friendly Southeast Missouri Hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[See all properties in Southeast Missouri](https://www.expedia.com/Hotel-Search?startDate=2026-11-27&endDate=2026-11-28&regionId=6058763&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true)

## Find amazing mountains vacations in Southeast Missouri

### How to plan for a mountain vacation in Southeast Missouri?

 The first step to planning your mountain vacation to Southeast Missouri is to decide what dates you want to go. In the winter months, fresh snowfall means you could hit the slopes at ski resorts near Southeast Missouri, while summer invites you to enjoy scenic hikes. It's a good idea to choose the type of accommodation you'd prefer, too. On Expedia, you'll encounter a vast array of options in Southeast Missouri, from famous chain hotels to charming cabins. The [vacation planning page](https://www.expedia.com/lp/b/vacations/planning) has more tips for organizing your Southeast Missouri mountain vacation.

### What amenities should I look for when booking a mountain resort in Southeast Missouri?

 When booking accommodation for your mountain vacation to Southeast Missouri, check to see if where you're staying has heating. Southeast Missouri's mountain air means it can feel fresh at night. If you're craving a special stay, look to see if the hotel offers mountain view rooms, or has a pool or hot tub to unwind in the evenings. Expedia's handy search filters include all these amenities and more, making it a breeze to book the right place to stay on your Southeast Missouri vacation package.

### Why should I choose a package for my mountain vacation in Southeast Missouri?

 Choosing a package for your Southeast Missouri vacation often works out cheaper thanks to the savings you get for bundling up your flights and hotel. You'll typically find it costs more when booking these separately. On Expedia, the green label even shows you how much you're saving. Packages also tend to be more flexible, meaning it's more likely you can cancel for free in case your 2026 plans change. You can usually secure your package by paying a small upfront deposit, whereas booking flights separately requires full payment.

### What does a Southeast Missouri package typically include?

 Return flight tickets, your accommodation, and applicable taxes are typically included when you book a mountain vacation package to Southeast Missouri . Hotels may include breakfast and Wi-Fi, while the airfare may include checked luggage. Certain resorts may even include ski passes. As each Southeast Missouri vacation package is different, be sure to double-check what's included before you confirm. If you want a hassle-free trip, consider booking Southeast Missouri all-inclusive vacation packages as these include all meals.

### How can I book my Southeast Missouri on Expedia?

 Comparing some of the best deals using the search wizard is one of the first steps to booking your Southeast Missouri mountain vacation on Expedia. Take advantage of the search filters to narrow down hundreds of options at the click of a button. If you've got a strict budget, use the maximum price filter to set your limit. When you've pinned down your Southeast Missouri package vacation, book it in just a few clicks. You'll also have the option to spread the cost with Expedia's [payment plans](https://www.expedia.com/lp/b/vacations/payment-plans).

### Why book your Southeast Missouri mountain vacation with Expedia?

 With meaty exclusive deals you won't find anywhere else, you'll keep more cash in your pocket when booking your Southeast Missouri vacation package on Expedia. No matter your preferences or tastes, you'll find the right place to stay thanks to the wide selection of accommodation. There are even last-minute deals, too. And if that's not enough, join One Key for free. Expedia's reward program lets you earn points on eligible trips and also gives you access to juicy member-only discounts.

### Can I cancel my mountain vacation package booking?

 Yes, as most of Expedia's mountain vacation packages to Southeast Missouri are flexible, you can often cancel for free. Doing so is easy, too—log in to the “Trips” section and follow the steps. Don't forget to double-check the cancellation policy before booking, as not all Southeast Missouri vacation packages are flexible. The good news is Expedia will display this to you before payment. Take advantage of the free cancellation search filter so you'll be able to narrow down your search to view only flexible Southeast Missouri vacation packages.

### What types of mountain accommodations are available in Southeast Missouri?

 5-star hotels, cozy mountain lodges, and quaint bed and breakfasts are some of the most popular types of mountain accommodations for your vacation to Southeast Missouri. Don't forget to use the filters to home in the amenities you'd like to have, too. Maybe it's a spacious suite with a mountain view or a traditional lobby with a fireplace—you'll find it all with Expedia's easy-to-use search wizard and wide choice of accommodation.

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- [Flights from Fredericktown](https://www.expedia.com/lp/flights/55114/flights-from-fredericktown)
- [Flights from Des Arc](https://www.expedia.com/lp/flights/553248634983251690/flights-from-des-arc)
- [Flights from Marquand](https://www.expedia.com/lp/flights/553248634983260789/flights-from-marquand)
- [Flights from Southeast Missouri](https://www.expedia.com/lp/flights/6058763/flights-from-southeast-missouri)
- [Flights to Southeast Missouri](https://www.expedia.com/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)
- [Flights to Annapolis](https://www.expedia.com/Cheap-Flights-To-Annapolis.d6282465.Travel-Guide-Flights)
- [Yoga Vacation Packages Southeast Missouri](https://www.expedia.com/lp/theme-vacations/yoga-vacations/6058763/Southeast-Missouri)
- [Walnut Hollow Lake](https://www.expedia.com/Walnut-Hollow-Lake-Annapolis.d6282503.Vacation-Attraction)
- [Crane Lake Recreation Area](https://www.expedia.com/Crane-Lake-Recreation-Area-Arcadia.d6282499.Vacation-Attraction)
- [Patterson Vacations](https://www.expedia.com/Patterson.d553248635975853657.Destination-Travel-Guides)
- [Visit Fredericktown](https://www.expedia.com/Fredericktown.dx55114)
- [Silver Mine Recreation Area](https://www.expedia.com/Silver-Mine-Recreation-Area-Fredericktown.d553248621592517772.Vacation-Attraction)
- [Visit Annapolis](https://www.expedia.com/Annapolis.dx6282465)
- [Millstream Gardens Conservation Area](https://www.expedia.com/Millstream-Gardens-Conservation-Area-Fredericktown.d553248621592517773.Vacation-Attraction)
- [Adults Only Vacation Packages Southeast Missouri](https://www.expedia.com/lp/theme-vacations/adults-only-vacations/6058763/Southeast-Missouri)
- [Visit Southeast Missouri](https://www.expedia.com/Southeast-Missouri.dx6058763)
- [K Bridge Recreation Area](https://www.expedia.com/K-Bridge-Recreation-Area-Annapolis.d6282501.Vacation-Attraction)
- [Johnson's Shut-ins State Park](https://www.expedia.com/Johnsons-Shut-Ins-State-Park-Missouri.d553248621555612544.Vacation-Attraction)
- [Visit Ironton](https://www.expedia.com/Ironton.dx6053585)
- [Hertz Rental Cars in Southeast Missouri](https://www.expedia.com/Hertz-Car-Rentals-In-Southeast-Missouri.d6058763-c40.Car-Rental-Guide-Suppliers)
- [Car rental Annapolis](https://www.expedia.com/Car-Rentals-In-Annapolis.d6282465.Car-Rental-Guide)
- [Top Rent a Car Rental Cars in Southeast Missouri](https://www.expedia.com/Top-Rent-A-Car-Car-Rentals-In-Southeast-Missouri.d6058763-c1028.Car-Rental-Guide-Suppliers)
- [Discount Car Rentals Rental Cars in Southeast Missouri](https://www.expedia.com/Discount-Car-Rentals-Car-Rentals-In-Southeast-Missouri.d6058763-c11.Car-Rental-Guide-Suppliers)
- [Car rental Greenville](https://www.expedia.com/Car-Rentals-In-Greenville.d553248634983564794.Car-Rental-Guide)
- [Localiza Colombia Rental Cars in Annapolis](https://www.expedia.com/Localiza-Colombia-Car-Rentals-In-Annapolis.d6282465-c1029.Car-Rental-Guide-Suppliers)
- [First-Car Rental Cars in Southeast Missouri](https://www.expedia.com/First-Car-Car-Rentals-In-Southeast-Missouri.d6058763-c1019.Car-Rental-Guide-Suppliers)
- [Car rental Fredericktown](https://www.expedia.com/Car-Rentals-In-Fredericktown.d55114.Car-Rental-Guide)
- [United Rental Cars in Southeast Missouri](https://www.expedia.com/United-Car-Rentals-In-Southeast-Missouri.d6058763-c1088.Car-Rental-Guide-Suppliers)
- [Car rental Central Fredericktown](https://www.expedia.com/Car-Rentals-In-Central-Fredericktown.d553248635975850047.Car-Rental-Guide)
- [Annapolis Vacation Rentals](https://www.expedia.com/Annapolis-Vacation-Rentals.d6282465.Travel-Guide-VacationRentals)
- [Southeast Missouri Vacation Rentals](https://www.expedia.com/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)
- [Things to do in Southeast Missouri](https://www.expedia.com/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)

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