--- title: "Weekend Getaways in Chillicothe, MO from $61 | Expedia" description: "Discover the best weekend getaways in Chillicothe. Browse hotels and vacation deals at Expedia for a perfect short escape." canonical: "https://www.expedia.com/tgp/lodging/theme/getaway/6058811/chillicothe" language: en-US market: US currency: USD prices_as_of: 2026-11-13T22:24:37Z --- # Weekend getaways in Chillicothe ![A steel bridge spanning a river, surrounded by dense forest.](https://images.trvl-media.com/place/6058811/c822c518-2b05-4fe1-8702-e820c1cde8f8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ### Upfront pricing Our total price for your stay includes taxes and fees ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) ### Be picky Search almost a million properties worldwide ## Check prices for these dates [Check prices for these dates, December 13 – 14, 2026](https://www.expedia.com/Hotel-Search?regionId=6058811&startDate=2026-12-13&endDate=2026-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Featured weekend hotel deals in Chillicothe ### [Motel 6 – Chillicothe, MO](https://www.expedia.com/Chillicothe-Hotels-Days-Inn-By-Wyndham-Chillicothe.h16391.Hotel-Information) ![A spacious living area with two armchairs, a wooden coffee table with a floral centerpiece, and a kitchen area with wooden cabinets and a television.](https://images.trvl-media.com/lodging/1000000/20000/16400/16391/7b7763eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: 1020 S Washington St, Chillicothe, MO, 64601, US - Location: Chillicothe - Star rating: 2.5/5 - Guest rating: 6.2/10 (456 reviews) - Price: $71 nightly (was $189), $160 total, Nov 20 - Nov 22, Total with taxes and fees ### [Super 8 by Wyndham Chillicothe](https://www.expedia.com/Chillicothe-Hotels-Super-8-By-Wyndham-Chillicothe.h459995.Hotel-Information) ![A hotel bathroom with a large bathtub, a television, a desk, and a chair.](https://images.trvl-media.com/lodging/1000000/460000/460000/459995/1966426c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: 580 Business Old Highway 36 E, Chillicothe, MO, 64601, US - Location: Chillicothe - Star rating: 2/5 - Guest rating: 6.6/10 (581 reviews) - Price: $107 nightly, $241 total, Nov 20 - Nov 22, Total with taxes and fees ### [Cobblestone Inn & Suites - Trenton](https://www.expedia.com/Chillicothe-Hotels-Cobblestone-Inn-Suites-Trenton.h1615553.Hotel-Information) ![A hotel room with a large bed, a smaller bed, a sofa, a desk, and a TV.](https://images.trvl-media.com/lodging/2000000/1620000/1615600/1615553/80915ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: 2900 Hoover Drive, Trenton, MO, 64683, US - Location: Trenton - Star rating: 2.5/5 - Guest rating: 9/10 (Wonderful, 338 reviews) - Price: $114 nightly (was $308), $259 total, Nov 20 - Nov 22, Total with taxes and fees ### [Best Western Brookfield](https://www.expedia.com/Chillicothe-Hotels-Best-Western-Brookfield.h693132.Hotel-Information) ![A hotel room with a large bathtub, a bed with a headboard, a desk, and a chair.](https://images.trvl-media.com/lodging/1000000/700000/693200/693132/w3840h2556x0y4-33ec27ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: 28622 Highway 11, Brookfield, MO, 64628, US - Location: Brookfield - Star rating: 2.5/5 - Guest rating: 9/10 (Wonderful, 381 reviews) - Price: $148 nightly, $321 total, Nov 20 - Nov 22, Total with taxes and fees ### [Countryside Escape! Cozy Studio w/ Patio](https://www.expedia.com/Chillicothe-Hotels-Countryside-Escape-Cozy-Studio-W-Patio.h136764378.Hotel-Information) ![A building with a covered entrance, a garage, and a vehicle parked outside.](https://images.trvl-media.com/lodging/137000000/136770000/136764400/136764378/6de51dd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Chillicothe, MO, US - Location: Chillicothe - Star rating: 3/5 - Guest rating: 10/10 (Exceptional, 1 review) - Price: $162 nightly, $342 total, Nov 20 - Nov 22, Total with taxes and fees ### [Westbridge Inn & Suites Carrollton](https://www.expedia.com/Chillicothe-Hotels-Westbridge-Inn-Suites-Carrollton.h898011.Hotel-Information) ![A modern hotel room with a spa area, including a bathtub, a flat-screen TV, and a seating area with ottomans.](https://images.trvl-media.com/lodging/1000000/900000/898100/898011/20605593.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: 1408 Highway 65 N, Carrollton, MO, 64633, US - Location: Carrollton - Star rating: 2/5 - Guest rating: 7.8/10 (Good, 194 reviews) - Price: $113 nightly, $246 total, Nov 20 - Nov 22, Total with taxes and fees ### ['red Barn Getaway' Chillicothe Countryside Home](https://www.expedia.com/Chillicothe-Hotels-Red-Barn-Getaway-Chillicothe-Countryside-Home.h113662483.Hotel-Information) ![A spacious living room with a fireplace, a mounted deer head, and a staircase leading to another level.](https://images.trvl-media.com/lodging/114000000/113670000/113662500/113662483/f49bfe48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Chillicothe, MO, US - Location: Chillicothe - Star rating: 3/5 - Price: $217 nightly, $460 total, Nov 20 - Nov 22, Total with taxes and fees ## Top Chillicothe Hotel Reviews ### [Best Western Brookfield](https://www.expedia.com/Chillicothe-Hotels-Best-Western-Brookfield.h693132.Hotel-Information) ![A hotel room with a large bathtub, a bed with a headboard, a desk, and a chair.](https://images.trvl-media.com/lodging/1000000/700000/693200/693132/w3840h2556x0y4-33ec27ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: 28622 Highway 11, Brookfield, MO, 64628, US - Location: Brookfield - Star rating: 2.5/5 - Guest rating: 9/10 (381 reviews) - Review: Was a perfect place to stop on our travels, by Tammie, November 8, 2026, rated 10/10 Excellent ### [Comfort Inn Marshall Station](https://www.expedia.com/Higginsville-Hotels-Comfort-Inn-Marshall-Station.h327351.Hotel-Information) ![A lobby with a reception desk, two red chairs, a small table with a lamp, and a large aquarium.](https://images.trvl-media.com/lodging/1000000/330000/327400/327351/66a2f078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Marshall - Review: It’s clean and quiet. Breakfast is good. One thing needs a attention is the toilet in our bedroom is a bit wobbly Otherwise we’ll be back., by Sinsery, January 31, 2025, rated 10/10 Excellent ### [Hotel Marceline](https://www.expedia.com/Marceline-Hotels-Hotel-Marceline.h90233839.Hotel-Information) ![A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table.](https://images.trvl-media.com/lodging/91000000/90240000/90233900/90233839/25d0be96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Marceline - Review: It is a nice hotel, well kept from the older days and themed with Disney scenes as it is the Boy Hood home of Walt Disney, by Debra, November 21, 2023, rated 10/10 Excellent ### [Red Roof Inn Cameron](https://www.expedia.com/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information) ![A kitchen with wooden cabinets, a toaster, a fruit bowl, and a waffle maker.](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/792b4c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Cameron - Review: We really enjoyed our stay in Springfield, IL and also our stay in Cameron, IL. I was impressed by the hospitality, cleanliness, comfortable bedding, the delicious snacks offered in the lobby and the accommodations offered to allow 3 adults and 2 children to all share a single room, saving us a good bit of money! The girls also enjoyed the hotel pool and the free breakfast was delicious both mornings in Springfield., by Shannon, June 10, 2025, rated 10/10 Excellent ### [Super 8 by Wyndham Richmond](https://www.expedia.com/Higginsville-Hotels-Super-8-By-Wyndham-Richmond.h906831.Hotel-Information) ![A spacious living area with a dining table, chairs, a chandelier, and a staircase.](https://images.trvl-media.com/lodging/1000000/910000/906900/906831/008fa704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Richmond - Review: We stay at this Super 8 whenever we are in Richmond. No complaints, ever., by dci, December 1, 2015, rated 10/10 Excellent ### [Night Inn](https://www.expedia.com/Higginsville-Hotels-Night-Inn.h4197199.Hotel-Information) ![A cozy room with a wooden floor, a ceiling fan, a refrigerator, a dining table with chairs, and various potted plants.](https://images.trvl-media.com/lodging/5000000/4200000/4197200/4197199/7d2ded2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Sweet Springs - Review: Rooms were very clean. Large room nice decor. Light breakfast was just perfect, by Anonymous traveler, October 29, 2019, rated 10/10 Excellent ### [SureStay Hotel by Best Western Higginsville](https://www.expedia.com/Higginsville-Hotels-SureStay-Hotel-By-Best-Western-Higginsville.h18181.Hotel-Information) ![A modern living room with a blue sofa, a coffee table, and a fireplace. There is a kitchen area with a red accent wall and a flat-screen TV mounted above the counter.](https://images.trvl-media.com/lodging/1000000/20000/18200/18181/e3dfac98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Higginsville - Review: Nice place to stay for the night., by Ronald Marsha Niki Natalie, August 19, 2024, rated 10/10 Excellent ### [Super 8 by Wyndham Cameron](https://www.expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information) ![A hotel bathroom with a wooden bathtub, a desk with a lamp, a chair, a television, and a microwave.](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Cameron - Review: We needed a room that could sleep 5 people, but I didn't expect one to be so roomy. There was space for 3 queen size beds, a sofa, and plenty of room to walk around. It was very comfortable as well. I would highly recommend staying here., by Cathy, December 1, 2016, rated 10/10 Excellent ### [Super 8 by Wyndham Sweet Springs](https://www.expedia.com/Higginsville-Hotels-Super-8-By-Wyndham-Sweet-Springs.h18982223.Hotel-Information) ![A hotel room with two beds, a nightstand, a lamp, and two framed black and white cityscape photographs on the wall.](https://images.trvl-media.com/lodging/19000000/18990000/18982300/18982223/6068920e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Sweet Springs - Review: Amazingly comfortable, clean, stay for a reasonably priced property. Newer strong quiet AC. Kind, helpful front desk staff. Great comfort food next door—steps from lobby., by Timothy, October 5, 2026, rated 10/10 Excellent ### [SureStay Hotel by Best Western Cameron](https://www.expedia.com/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information) ![A hotel room with two beds, a desk, a television, and a bathroom visible through an open door.](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Cameron - Review: I have stayed here 5 times in the last few years for dog events, it isnt fancy but has a great staff and dog walking area, basic breakfast and easy access right off of hwy-36 if I could change one thing it would be to service the dog poop recepticle it was broken and overflowing with dog poop that owners had picked up from their walking area., by Dawn, February 26, 2024, rated 10/10 Excellent ### [Super 8 by Wyndham Bethany MO](https://www.expedia.com/St-Joseph-Hotels-Super-8-By-Wyndham-Bethany-MO.h897802.Hotel-Information) ![A hotel room with a bed, two armchairs, a desk with a chair, a TV, and a painting on the wall.](https://images.trvl-media.com/lodging/1000000/900000/897900/897802/543e293f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Bethany - Review: I absolutely loved they had recliners in the room. It is really nice and comfy to watch tv in a recliner rather then the bed!! Very nice touch, by Jessica, December 18, 2024, rated 10/10 Excellent ### [Westbridge Inn & Suites Carrollton](https://www.expedia.com/Chillicothe-Hotels-Westbridge-Inn-Suites-Carrollton.h898011.Hotel-Information) ![A modern hotel room with a spa area, including a bathtub, a flat-screen TV, and a seating area with ottomans.](https://images.trvl-media.com/lodging/1000000/900000/898100/898011/20605593.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: 1408 Highway 65 N, Carrollton, MO, 64633, US - Location: Carrollton - Star rating: 2/5 - Guest rating: 7.8/10 (194 reviews) - Review: Excellent staff!!, by bradley, January 5, 2025, rated 10/10 Excellent ### [Family Budget Inn Bethany](https://www.expedia.com/St-Joseph-Hotels-Family-Budget-Inn-Bethany.h1772930.Hotel-Information) ![A reception desk with a stone wall backdrop, a wooden door, and a sign indicating a family budget inn.](https://images.trvl-media.com/lodging/2000000/1780000/1773000/1772930/e3e4381c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Bethany - Review: As always, you can count on this place for clean, decent room at good price. A perk right now is the availability of places to plug extension cord in to keep my diesel engine happy and ready to start in the frigid temperatures currently experiencing. It's not a big deal to most people but those driving vehicles with diesel engines appreciate it. Only place I stay when in the area as it's very truck and trailer friendly., by Peggy, February 3, 2022, rated 10/10 Excellent ### [Quality Inn & Suites Bethany](https://www.expedia.com/St-Joseph-Hotels-Quality-Inn-Suites-Bethany.h888644.Hotel-Information) ![A hotel room with a desk, two chairs, a sofa, and a patterned carpet.](https://images.trvl-media.com/lodging/1000000/890000/888700/888644/18d811f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Bethany - Review: Good room, amenities, and price., by Patricia, May 6, 2024, rated 10/10 Excellent ### [Hotel Lexihill](https://www.expedia.com/Higginsville-Hotels-Hotel-Lexihill.h19760589.Hotel-Information) ![A hotel room with a bed, bedside tables, a desk, and a lamp.](https://images.trvl-media.com/lodging/20000000/19770000/19760600/19760589/0bd8ea38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Lexington - Review: Room was very clean, bed was comfortable, and AC worked. They are renovating the hotel so construction started early in the morning, probably to beat the heat. A comfortable bed and shower was all we needed., by Anonymous traveler, June 20, 2020, rated 10/10 Excellent ## Find out more about Chillicothe ##### Weekend Getaways in Chillicothe Weekend getaways in Chillicothe are a popular short-break option for couples, solo travelers, and groups of friends looking to relax, explore, or enjoy a change of scenery without extensive planning. Couples can enjoy relaxed experiences such as dining, scenic walks, or cultural activities, while solo travelers can explore flexible itineraries that balance sightseeing and downtime. If its a group trip, explore social, entertainment-focused experiences that fit into a short trip. Weekend travel generally peaks on Friday and Saturday nights, with a slightly quieter pace on Sundays, making it an ideal window for quick, refreshing breaks. ##### Reasons to book a Weekend Getaway in Chillicothe Weekend getaways in Chillicothe are a popular short-break option that offer a simple way to recharge, break from routine, and make the most of limited time, providing the chance to experience a new place without needing extended time off work or other commitments. ##### Where to stay in Chillicothe For a 2–3 day stay in Chillicothe, the best areas are usually those that keep you close to key attractions and transport links so you can make the most of a short visit. Central neighborhoods are ideal for easy access to landmarks, dining, and nightlife, while waterfront or scenic districts offer a more relaxed break with memorable views. Well-connected areas near major train stations or airports are also practical choices, making it simple to move around efficiently without wasting time on travel. Different neighborhoods can also suit different travel styles. Central and entertainment-focused areas often work well for couples looking for a mix of dining and a lively center, while solo travelers may prefer well-connected districts that offer convenience and flexibility. Group travelers often benefit from busy areas with plenty of entertainment, shared activities, and larger hotel options. Choosing the right neighborhood in Chillicothe helps balance convenience, comfort, and experience for a well-rounded short stay. ##### Top amenities for a weekend stay in Chillicothe When choosing a weekend stay in Chillicothe on Expedia, look for essentials like fast Wi-Fi, flexible check-in and check-out, and easy transport access to help you make the most of a short trip, along with comfortable bedding, climate control, and quiet rooms for proper rest between plans. Added conveniences such as on-site dining, breakfast options, and 24-hour reception can streamline your stay, while features like gyms, spas, or pools add extra value for a more relaxing break. Flexible cancellation is also helpful for keeping your weekend plans stress-free and adaptable, making it easier to enjoy a smooth, well-paced stay in Chillicothe. ##### Best hotel types for Weekend Getaways in Chillicothe Central hotels and boutique hotels are popular choices for weekend getaways in Chillicothe, offering easy access to attractions, dining, and local experiences. City hotels in well-connected areas are ideal for convenience, with transport links that make it easy to get around. For a more relaxed pace, residential or quieter neighborhoods provide a calmer stay while still keeping the city within easy reach. Full-service hotels are also a strong option for groups, with flexible room setups and amenities that support shared, short stays. ##### Best time to go for a Weekend Getaway in Chillicothe The best time for a weekend getaway in Chillicothe is usually during shoulder seasons, when weather conditions are pleasant and areas are less filled with tourists, creating a more relaxed travel experience. Weekends outside major holidays and local events also tend to offer a better balance of availability and comfort, making it easier to enjoy the destination at a comfortable pace. In terms of booking, confirming a stay a few weeks in advance often provides the best choice of hotels and locations, while more flexible travelers may still find good options closer to the weekend during quieter periods. Friday and Saturday nights are typically the most popular, so planning around slightly less busy weekends or adding a Sunday night can sometimes improve both value and availability. ##### Tips to save on a weekend getaway in Chillicothe 1. Travel during quieter weekends Choosing weekends outside major holidays, events, or peak travel periods in Chillicothe can often lead to better rates and more availability across a wider range of hotels. 2. Stay slightly outside the main areas Hotels in well-connected but less central neighborhoods are often more affordable, while still keeping attractions and dining within easy reach. 3. Be flexible with hotel type and room choice Opting for standard rooms or business and city hotels instead of premium or boutique stays can help reduce costs without sacrificing comfort. 4. Compare package deals for better value Weekend getaway packages that bundle hotel stays with flights can often provide better overall value than booking each element separately. ##### Why book with Expedia? Booking your hotel on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence. Join our One Key™ travel rewards program to unlock additional savings. It's free to join. ## Other language versions ```yaml hreflang: x-default: https://www.expedia.com/tgp/lodging/theme/getaway/6058811/chillicothe en-US: https://www.expedia.com/tgp/lodging/theme/getaway/6058811/chillicothe ```