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Compare 430 hotels close to Mayo Clinic with room rates, reviews, and availability. Most hotels are fully refundable.

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4.0 star property
9.4 out of 10, Exceptional, 607 reviews
"Modern and convenient for a Mayo visit with shuttle service! "
The price is $111
$130 total
includes taxes & fees
Jul 1 - Jul 2
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
7.6 out of 10, Good, 1,207 reviews
"Overnight stay for doctor appointments. Busy at check in, everything else was fine."
The price is $108
$125 total
includes taxes & fees
Jun 14 - Jun 15
Kahler Inn and Suites - Mayo Clinic Area
Kahler Grand Hotel
3.0 star property
8.2 out of 10, Very Good, 1,007 reviews
"Have stayed at Kahler grand hotel for over 20 years "
The price is $149
$172 total
includes taxes & fees
Jun 8 - Jun 9
Kahler Grand Hotel
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Hyatt House Rochester/Mayo Clinic Area
3.0 star property
9.0 out of 10, Wonderful, 554 reviews
"Great location for the mayo"
The price is $111
$128 total
includes taxes & fees
Jul 2 - Jul 3
Hyatt House Rochester/Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
7.8 out of 10, Good, 1,006 reviews
"Pillows were very flat. But Bill at the front desk was super nice and helpful. "
The price is $89
$103 total
includes taxes & fees
Jun 2 - Jun 3
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 star property
8.8 out of 10, Excellent, 543 reviews
"Great service"
The price is $121
$142 total
includes taxes & fees
Jun 16 - Jun 17
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, 1,001 reviews
"Very clean"
The price is $100
$115 total
includes taxes & fees
Jun 9 - Jun 10
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
8.0 out of 10, Very Good, 1,003 reviews
"The room was small, but okay for a single person. The bed was okay, it was clean. Loved the bench above the air conditioner/heater. The breakfast was standard cold and hot items, but not much for sitting, so you may need to eat in your room. The down fall was I could hear a TV going in the next room and in the other room, hear a phone alarm going off."
The price is $67
$77 total
includes taxes & fees
Jun 16 - Jun 17
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Hampton Inn Rochester-South
2.5 star property
9.0 out of 10, Wonderful, 1,004 reviews
"I have a wonderful time is staying there thank you so much team "
The price is $85
$97 total
includes taxes & fees
Jun 23 - Jun 24
Hampton Inn Rochester-South
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
8.2 out of 10, Very Good, 392 reviews
"Very helpful "
The price is $88
$102 total
includes taxes & fees
Jun 9 - Jun 10
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
9.4 out of 10, Exceptional, 86 reviews
"Wonderful rooms and accommodations. "
The price is $118
$136 total
includes taxes & fees
Jun 6 - Jun 7
Residence Inn by Marriott Rochester Mayo Clinic Area South
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
9.0 out of 10, Wonderful, 620 reviews
"Great place to stay. Accessible to everything."
The price is $129
$149 total
includes taxes & fees
Jun 7 - Jun 8
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
9.8 out of 10, Exceptional, 282 reviews
"Great hotel. Great complete hot breakfast (FREE) We stay at a studio room 500SF for only $139 per night with a full kitchen and real pots and pots and dishes. Very nice in comparison with some dark stinky dives around. Super close to the Gonda Building (5 min walk), they also have a Spyhouse coffee house at the premises. We are going to look for TownPlace Suites by Marriot from now on. A really great concept. 10 Stars for sure!! One thing we didnt like is the cheap small batrroom mirror and...
The price is $118
$136 total
includes taxes & fees
Jun 7 - Jun 8
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
2.5 star property
8.8 out of 10, Excellent, 611 reviews
"Everything was very well done, all of the staff very friendlyand eager to please.. Breakfast was quite delicious. "
The price is $121
$140 total
includes taxes & fees
Jun 6 - Jun 7
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
9.6 out of 10, Exceptional, 626 reviews
"The location was close enough to everything but quiet enough as well. One of the most comfortable beds to sleep in too!"
The price is $118
$136 total
includes taxes & fees
Jun 8 - Jun 9
Home2 Suites by Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic Area
3.5 star property
9.6 out of 10, Exceptional, 338 reviews
"The hotel was very Beautiful and very clean. It was beautifully decorated. The staff were all super helpful and courteous. The only complaint I have is that the bed was hard as a rock. We had a very nice room with a king bed and beautiful views, but that bed was hard as a rock. That’s the only thing that could use an Upgrade. The room and the bathroom were extremely clean. I would definitely stay there again with a softer bed. And also housekeeping put a fresh sheet on there had a hole in it on...
The price is $178
$205 total
includes taxes & fees
Jun 8 - Jun 9
Hilton Rochester Mayo Clinic Area
Quality Inn near Medical Center
2.5 star property
8.0 out of 10, Very Good, 500 reviews
"Staff was great. Older property but very clean. Good breakfast. Will be back!"
The price is $67
$77 total
includes taxes & fees
Jun 17 - Jun 18
Quality Inn near Medical Center
Brentwood Inn & Suites
2.5 star property
8.6 out of 10, Excellent, 1,001 reviews
"Close to Mayo Clinic at a reasonable price"
The price is $119
$137 total
includes taxes & fees
Jun 7 - Jun 8
Brentwood Inn & Suites
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
8.2 out of 10, Very Good, 1,008 reviews
"The staff went above and beyond in their care for Mayo Clinic patients. The onsight restaurant, Twigs, was top notch. The shuttle service to the clinics were always on time. The room we stayed in needed some updating, but it was fine for the time we were there."
The price is $117
$135 total
includes taxes & fees
Jun 6 - Jun 7
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Aspen Select
3.5 star property
8.6 out of 10, Excellent, 1,002 reviews
"If you need a wheelchair, you might not get one. First night checkin wheelchair was available. Second night, after a 10 hour day at St Marys, there was no wheelchair available. UNDERSTAND, Aspen Select does not guarantee wheelchairs. But a hotel property this close to Mayo St Mary's hospital should be able to guarantee the use of a wheelchair. Otherwise our stay was pleasant. "
The price is $125
$159 total
includes taxes & fees
Jun 2 - Jun 3
Aspen Select
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Mayo Clinic Travel Info

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Frequently asked questions

What's the area like around Mayo Clinic?

Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 168 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic?

Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hyatt House Rochester/Mayo Clinic Area.

How many hotels will I be able to find near Mayo Clinic?

Expedia has 168 hotels and other accommodations within a mile from Mayo Clinic.

If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?

For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.

What can I see and do near Mayo Clinic?

You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

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