Photo by Catherine Edejer-McCormick

Find Resorts & Hotels with Spas in South San Francisco, CA

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Pick from 30 South San Francisco Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Savor the Peace at a Comfy Cottage Minutes from Downtown SF
Property grounds
Savor the Peace at a Comfy Cottage Minutes from Downtown SF
10.0 out of 10, Exceptional, (1)
"My family of four stayed here for two nights. The rental was very clean, quiet, modern and comfortable. We had a decent view of the surroundings. Parking is always an issue in the city and the secure parking accommodated our lifted truck perfectly! The hosts were prompt to reply to questions and requests. The rate was reasonable and we would stay here again."
Savor the Peace at a Comfy Cottage Minutes from Downtown SF
Lovely Mango House near SFO and Paradise Valley
Fridge, microwave, oven, stovetop
Lovely Mango House near SFO and Paradise Valley
9.8 out of 10, Exceptional, (8)
"We really enjoyed our stay at this property. It is exactly as it is pictured. We felt very safe in the neighborhood and the hillside views were beautiful! It was about a 20 minute drive to a lot of the sites in San Francisco and traffic was never an issue. There is also a grocery store about 5 minutes away. The host was amazing! They had the fridge stocked with bottled water and Dim Sum Bakery when we arrived. We would definitely stay here again!"
Lovely Mango House near SFO and Paradise Valley
♥SFO SF Cute, Cozy, Private Studio Convenient Location-Bay Area/Silicon Valley♥
Living area
♥SFO SF Cute, Cozy, Private Studio Convenient Location-Bay Area/Silicon Valley♥
9.6 out of 10, Exceptional, (12)
"Nice property, just what is needed if you are just using to sleep and shower, which is all we needed it for. Communication with owner was quick and easy. Had some confusion about the listing but it was all taken care of. There is no ocean view or hot tub lol. Previous reviews are correct in that it is a unit made from a garage. So basically two rooms, bathroom and everything else. Overall, good location, about 20-30 minutes from the sites in San Fran."
♥SFO SF Cute, Cozy, Private Studio Convenient Location-Bay Area/Silicon Valley♥
Beautiful 1 Bedroom Apartment minutes to SFO in Victorian Home (Can sleep 4)
Exterior
Beautiful 1 Bedroom Apartment minutes to SFO in Victorian Home (Can sleep 4)
9.6 out of 10, Exceptional, (131)
"Lovely snacks and welcome card on the dining table. Comfortable electric fireplace and nice bed to sleep in."
Beautiful 1 Bedroom Apartment minutes to SFO in Victorian Home (Can sleep 4)
NEWLY FURNISHED! RECENTLY RENOVATED! CUTE SPACE! CLOSE TO SFO!
Fridge, microwave, oven, stovetop
NEWLY FURNISHED! RECENTLY RENOVATED! CUTE SPACE! CLOSE TO SFO!
9.0 out of 10, Wonderful, (2)
"I wanted some place to unwind after a long road trip and this South San Francisco gem was just perfect. With all of the comforts of home, I was able to prepare meals, sleep as I pleased and enjoy solitude and silence"
The price is $130
$308 total
includes taxes & fees
Jun 12 - Jun 13
NEWLY FURNISHED! RECENTLY RENOVATED! CUTE SPACE! CLOSE TO SFO!
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Exterior
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
3.0 star property
8.4 out of 10, Very Good, (957)
"Great stay"
The price is $147
$174 total
includes taxes & fees
Jun 7 - Jun 8
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Holiday Inn Express San Francisco-Airport North, an IHG Hotel
Pool
Holiday Inn Express San Francisco-Airport North, an IHG Hotel
2.5 star property
7.8 out of 10, Good, (1036)
"The room is clean. Check in took a while since there is only 1 staff helping. The lobby wasn't inviting & with insects flying."
The price is $97
$123 total
includes taxes & fees
Jun 9 - Jun 10
Holiday Inn Express San Francisco-Airport North, an IHG Hotel
Days Inn by Wyndham San Francisco S/Oyster Point Airport
Standard Room, 2 Queen Beds | In-room safe, desk, blackout drapes, iron/ironing board
Days Inn by Wyndham San Francisco S/Oyster Point Airport
2.0 star property
6.2 out of 10, (1003)
"The friendly front desk representative that greated me. Professional and made the checking in a pleasant experience. I appreciated her making me feel welcomed. It was a pleasant stay. "
The price is $84
$104 total
includes taxes & fees
Jun 9 - Jun 10
Days Inn by Wyndham San Francisco S/Oyster Point Airport
Explore the Best of the City! Free Breakfast, Free Shuttle, Full Kitchen!
TV
Explore the Best of the City! Free Breakfast, Free Shuttle, Full Kitchen!
The price is $141
$185 total
includes taxes & fees
Jun 7 - Jun 8
Explore the Best of the City! Free Breakfast, Free Shuttle, Full Kitchen!
2 Spacious Good-Value Accommodations! Near San Francisco Zoo, Free Breakfast
Exterior
2 Spacious Good-Value Accommodations! Near San Francisco Zoo, Free Breakfast
The price is $440
$575 total
includes taxes & fees
Jun 2 - Jun 3
2 Spacious Good-Value Accommodations! Near San Francisco Zoo, Free Breakfast
Don't see what you're looking for?
See all available properties in South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South San Francisco Resorts & Hotels with Spas information

 

Resorts & Hotels with Spas in South San Francisco

30

Highest price
$661
Cheapest price
$84
Number of guest reviews
2,995
Total number of hotels in South San Francisco
5,166

 

Frequently asked questions

Looking for a spa hotel in South San Francisco?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in South San Francisco. Enjoy the shopping and cafes during your vacation. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your vacation.
What is the best spa hotel in South San Francisco?
Comfort Inn and Suites San Francisco Airport North is a top spa hotel with 169 rooms, free WiFi, and a fireplace in the lobby. Other popular spa hotels in South San Francisco include Inn By The SFO and Home2 Suites by Hilton San Francisco Airport North.
How many spa hotels will I find in South San Francisco?
Among Expedia’s 151 accommodation options in South San Francisco, there are 6 spa hotels.
What's there to see and do in South San Francisco?
Take in some sights and attractions while you’re in South San Francisco by visiting San Francisco Bay, Santa Cruz Mountains, and See’s Candies. If you have spare time during your trip, you might want to make a stop at San Bruno Point Park and K1 Speed San Francisco.
What is a South San Francisco spa hotel?
Spa hotels in South San Francisco provide lodging and have an on-site spa offering services including massages and body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

Recent reviews of South San Francisco hotels
Expedia verified reviews

Handlery Union Square Hotel

Handlery Union Square Hotel

5/5 Excellent
Artistic treasure
"Great location, lots of charm"
A verified traveler stayed at Handlery Union Square Hotel
Posted 15 hours ago
Handlery Union Square Hotel