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Cape Girardeau Vacation Rentals

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Vacation Rentals in Cape Girardeau

Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, 114 reviews
"The place was perfect for our stay and was close to the farmers market and downtown shops. Highly recommend for location!"
The price is $150
$243 total
includes taxes & fees
Jun 4 - Jun 5
Serenity South -- Gardens, River-Views, and Refreshing Space
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
9.6 out of 10, Exceptional, 19 reviews
"Loved the vibe of the house. Very clean & nice."
The price is $91
$148 total
includes taxes & fees
Jun 4 - Jun 5
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Charming 2-Story- C.1847 - River Views - Fast Wifi
9.6 out of 10, Exceptional, 10 reviews
"Cape Girardeau is about the halfway point for us (Wisconsin) and friends from Mississippi. This VRBO is ideally located within walking distance to plenty of restaurants, shops and bars. Property is very clean, has the basics and communication with the owner was super easy. The saloon-style doors for the downstairs bathroom were a little unexpected, but we made it work. We enjoyed our stay and would recommended this property for a long weekend."
Charming 2-Story- C.1847 - River Views - Fast Wifi
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4-acre Home with Multiple Decks: Pool Table | Putt-Putt I 4 miles to Downtown
9.2 out of 10, Wonderful, 20 reviews
"This property was perfect for our family and our 4 boys really enjoyed the mini golf, pool table, couch swing and signing the wall. We will definitely be coming back on our travels. Unique decor and beautiful space! "
The price is $275
$386 total
includes taxes & fees
Jun 5 - Jun 6
4-acre Home with Multiple Decks: Pool Table | Putt-Putt I 4 miles to Downtown
Quaint, Beautiful Home next to SEMO and Hospital
9.8 out of 10, Exceptional, 19 reviews
"Clean, quiet and close to what we needed. Great overall experience"
Quaint, Beautiful Home next to SEMO and Hospital
Loft Apartment Across From Semo University Houch Field House. Walk To Events
10.0 out of 10, Exceptional, 71 reviews
"Love this place so comfortable and great location."
The price is $150
$182 total
includes taxes & fees
Jun 4 - Jun 5
Loft Apartment Across From Semo University Houch Field House. Walk To Events
Updated 3 bedroom unit with balcony!
10.0 out of 10, Exceptional, 1 review
"Very nice place only downsize albeit cute is the claw foot tub with make shift shower, The unit worked very well for what we were looking for near SEMO campus"
Updated 3 bedroom unit with balcony!
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
9.0 out of 10, Wonderful, 2 reviews
"First, the owner and their communication was fantastic. The space was exactly as described, comfortable and clean. The proximity to everything from the river, to downtown and even to the great restaurants on upper Broadway is walkable and great. The “but” is that we stayed Friday and Saturday and it is located right on Broadway (popular cruising street) next to a popular bar that itself is loud and fills the parking area out back with partying till near 2 am. Truly, otherwise, a great stay."
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
Charming Secluded Getaway Cabin within minutes of amenities
10.0 out of 10, Exceptional, 9 reviews
"Quick weekend away fro St. Louis, my wife and wanted some quiet. This property was great but was also convenient to lots of restaurants, antiques and hiking around Cape Girardeau area. 12 mins from Trail of Tears state park about 15 from town. Quick responses from our host and easy to work with."
Charming Secluded Getaway Cabin within minutes of amenities
Little Blue Cottage on Spanish
8.8 out of 10, Excellent, 32 reviews
"We stayed here to visit our two children going to SEMO. Everything about the place was perfect for a couple. The place was cute and the location was perfect"
The price is $90
$110 total
includes taxes & fees
Jun 4 - Jun 5
Little Blue Cottage on Spanish
The Twisted Sassafras Treehouse
10.0 out of 10, Exceptional, 7 reviews
"The property was exactly as advertised. They’ve truly thought of so many little things that made our stay so enjoyable. There was a severe weather alert at 4 am during our stay and the hosts were checking on us the entire time to be sure all was well. We will definitely be back, for a longer stay next time! 🙂"
The Twisted Sassafras Treehouse
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
10.0 out of 10, Exceptional, 202 reviews
"beautiful place. great location. recommend to anyone"
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau
10.0 out of 10, Exceptional, 3 reviews
"Gorgeous home with unique finishings and a lot of attention to detail. A very quick trip did not allow for relaxing on the back screened in porch. "
Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau
Steps to Southeast Hospital - Fast Wifi - King Bed
10.0 out of 10, Exceptional, 2 reviews
"The house was perfect for our group. It was in a great location and was exactly as advertised. I would definitely stay here again!"
Steps to Southeast Hospital - Fast Wifi - King Bed
Cozy Westend 4 queen beds, clean, quiet with a walk out basement
9.0 out of 10, Wonderful, 16 reviews
"Very nice, well kept place. Host is very accommodating"
Cozy Westend 4 queen beds, clean, quiet with a walk out basement
Large Home next to Southeast Hospital - 2 King Beds - Fast Wifi
10.0 out of 10, Exceptional, 4 reviews
"This was a great place for us to stay while in town for a family emergency. We will be staying here again the next time we visit. Great communication, comfortable beds, clean and fully stocked with supplies."
Large Home next to Southeast Hospital - 2 King Beds - Fast Wifi
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
10.0 out of 10, Exceptional, 83 reviews
"The listing led us to believe that this was a secluded cabin, when it was really next to their other available cabin. There wasn't anything noted on the rental info that identified between the two cabins. We ended up walking around to the doors of the wrong cabin. There were very few towels available considering ones necessary for the hot tub. Other than that, and the eclectic dish and cup selection, it was quite peaceful and it did feel very private even with people in the neighboring cabin....
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
New cabin in the woods with private hot tub
10.0 out of 10, Exceptional, 74 reviews
"Beautiful property, great cabin, roomy and super comfortable. The hot tub was great, the ambience of the woods, perfect!"
New cabin in the woods with private hot tub
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
10.0 out of 10, Exceptional, 338 reviews
"The cabin was adorable. The grounds around the pond and the cabin were all neatly mowed. Pond gave us extra excitement for our short trip as we fished. Really enjoyed our stay in this great little cabin. It didn’t bother us as we read all the amenities, but there is no stove. Just know this. There is a microwave though. Also the DIRECTV has about every station you can possibly think of to watch.Including Pay stations. This is a 9 out of 10. Super relaxing!"
The price is $117
$195 total
includes taxes & fees
Jun 9 - Jun 10
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Minutes from Giant City - SIU - Shawnee Winetrail - Cedar Lake - Shawnee Forest!
9.4 out of 10, Exceptional, 19 reviews
"I very much enjoyed staying at this cabin. It was clean, comfortable & close to the Shawnee National Forest & the Wine Trail. The bed & furniture were comfortable. The kitchenette allowed me to have all meals in, as it has a half-refrigerator, microwave, sink, coffeemaker, plates, glasses & mugs. The bathroom towels were luxurious & there was ample soap, shower gel, shampoo & conditioner. The heat & air-conditioning were easy to use. I was able to sit out on the deck every morning, even when it...
Minutes from Giant City - SIU - Shawnee Winetrail - Cedar Lake - Shawnee Forest!
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See all available properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cape Girardeau Vacation Rental Travel Info

Other types of properties in Cape Girardeau you may be interested in

Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, 1,010 reviews
"Always a great place to stay. Staff is great, rooms are clean, breakfast is good, great family environment."
The price is $67
$76 total
includes taxes & fees
Jun 17 - Jun 18
Auburn Place Hotel And Suites
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, 1,009 reviews
"Very friendly and welcoming staff. Clean rooms. Decent breakfast. Lots of restaurants close by. "
The price is $66
$74 total
includes taxes & fees
Jun 9 - Jun 10
Pear Tree Inn Cape Girardeau West
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, 1,000 reviews
"Always love our stays at this location! Friendly and attentive!"
The price is $112
$127 total
includes taxes & fees
Jun 16 - Jun 17
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Everything you need to know about Cape Girardeau vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Cape Girardeau vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Cape Girardeau vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Cape Girardeau vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Cape Girardeau. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Cape Girardeau in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $90 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Cape Girardeau rentals

At Expedia, we put the best Cape Girardeau vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Cape Girardeau rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Cape Girardeau vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Cape Girardeau. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Cape Girardeau?

Yes, we offer vacation rentals in Cape Girardeau near Cape Splash Family Aquatic Center, or you can select a more remote option if you're looking for extra privacy while you relax. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your vacation.

What are some of the best vacation home rentals in Cape Girardeau?

Serenity South -- Gardens, River-Views, and Refreshing Space: This Cape Girardeau vacation home rental is located on a river and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Cape Girardeau include Little Blue Cottage on Spanish and Charming 2-Story- C.1847 - River Views - Fast Wifi.

How many vacation rentals will I find in Cape Girardeau?

Choose from 23 Expedia vacation rentals in Cape Girardeau for a memorable vacation.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Riverfront Bridge Park and Trail of Tears State Park are a couple of great spots to enjoy the outdoors. While here, Isle Casino Cape Girardeau and Show Me Center are other places worth a visit.

What are vacation rentals like in Cape Girardeau?

Vacation rentals are private properties you can book for a couple days or more in Cape Girardeau. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.

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