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Find hotels in Duquesne, MO from $66

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    Check prices for these dates, December 14 – 15, 2026

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    Our top choices for Duquesne hotels

    1. La Quinta Inn & Suites by Wyndham Joplin

    An indoor swimming pool with clear glass walls, a lounge area with chairs, and a view of a building outside.

    2. Comfort Inn Joplin I-44

    A hotel lobby with a wooden floor, a sofa, a dining table, chairs, and pendant lighting.

    3. Drury Inn & Suites Joplin

    A pool area with a hot tub, lounge chairs, and a view through large windows.

    4. Residence Inn by Marriott Joplin

    A spacious lobby with a stone fireplace, orange armchairs, and a round coffee table.

    5. Holiday Inn Joplin by IHG

    A multi-story hotel with a stone facade, a covered entrance, and a parking area.

    6. Sleep Inn & Suites Webb City

    A hotel room with a sofa set, a small table with a lamp, a TV on the wall, and a decorative wall with a tree pattern.

    7. Home2 Suites by Hilton Joplin, MO

    An outdoor seating area with green sofas and tables, a stone wall, and a building entrance with glass doors.

    8. Days Inn by Wyndham Joplin

    A hotel lobby with a reception desk, wooden chairs, a large window, and a potted plant.

    9. Homewood Suites by Hilton Joplin

    A spacious hotel lobby with a central seating area, multiple tables, and a large chandelier.

    10. Best Western The Oasis at Joplin

    A modern office space with two desks, office chairs, a large window with a view, and a ceiling fan.

    11. Microtel Inn & Suites by Wyndham Joplin

    A building with a covered entrance, a bench outside, and a clear sky.

    12. Quality Inn Joplin I-44

    A breakfast bar with a coffee machine, waffle maker, and fruit display.

    13. Westport Inn

    A bedroom with a wooden headboard, a large bed with white bedding and a brown throw blanket, a bedside table, and wall decor including a circular wall hanging and a hanging light fixture.

    14. Fairfield Inn by Marriott Joplin

    A hotel lobby with a stone fireplace, a dining area, and a seating area with two armchairs and a coffee table.

    15. Plaza Motel

    A modern hotel room with a large bed, a desk, a chair, and a mirror.

    16. Sleep Inn South Joplin

    A lobby with a staircase, two beige armchairs with green cushions, a small table with a lamp, and a reception desk.

    17. Candlewood Suites Joplin by IHG

    A hotel with a yellow facade, a blue and red flag, and a sign that reads 'CANDLEWOOD SUITES'.

    18. Downstream Casino Resort

    A swimming pool with a reflection of lights, a building with a unique facade, and a bar area.

    19. TownePlace Suites Marriott Joplin

    An outdoor patio with a grill, seating, and a stone fireplace.

    20. Super 8 by Wyndham Joplin

    A hotel dining area with tables and chairs, a kitchen area with a coffee station, and a flat-screen TV mounted on the wall.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Top Duquesne Hotel Reviews

    Sleep Inn & Suites Webb City

    A hotel room with a sofa set, a small table with a lamp, a TV on the wall, and a decorative wall with a tree pattern.

    Homewood Suites by Hilton Joplin

    A spacious hotel lobby with a central seating area, multiple tables, and a large chandelier.

    Residence Inn by Marriott Joplin

    A spacious lobby with a stone fireplace, orange armchairs, and a round coffee table.

    Holiday Inn Joplin by IHG

    A multi-story hotel with a stone facade, a covered entrance, and a parking area.

    Downstream Casino Resort

    A swimming pool with a reflection of lights, a building with a unique facade, and a bar area.

    Comfort Inn Joplin I-44

    A hotel lobby with a wooden floor, a sofa, a dining table, chairs, and pendant lighting.

    Fairfield Inn by Marriott Joplin

    A hotel lobby with a stone fireplace, a dining area, and a seating area with two armchairs and a coffee table.

    Sleep Inn South Joplin

    A lobby with a staircase, two beige armchairs with green cushions, a small table with a lamp, and a reception desk.

    TownePlace Suites Marriott Joplin

    An outdoor patio with a grill, seating, and a stone fireplace.

    Quality Inn Joplin I-44

    A breakfast bar with a coffee machine, waffle maker, and fruit display.

    Candlewood Suites Joplin by IHG

    A hotel with a yellow facade, a blue and red flag, and a sign that reads 'CANDLEWOOD SUITES'.

    Best Budget Inn

    A covered outdoor area with columns, potted plants, and a view of a lake.

    Westport Inn

    A bedroom with a wooden headboard, a large bed with white bedding and a brown throw blanket, a bedside table, and wall decor including a circular wall hanging and a hanging light fixture.

    Best Western Big Spring Lodge

    A hotel room with two beds, a desk, a lamp, a TV, and a window with curtains.

    Plaza Motel

    A modern hotel room with a large bed, a desk, a chair, and a mirror.

    Best Western The Oasis at Joplin

    A modern office space with two desks, office chairs, a large window with a view, and a ceiling fan.

    Holiday Inn Express And Suites Joplin Southeast by IHG

    Pool

    Frequently Asked Questions

    What is the best area to stay in Duquesne?

    The best area to stay in Duquesne is generally near the main commercial areas along Missouri Route 171 (MO-171) or Interstate 44 (I-44) for convenient access to amenities and regional travel.

    For travelers prioritizing ease of access and modern conveniences, staying near the intersection of MO-171 and I-44 is the most practical choice. This area features several hotels, restaurants, and retail establishments, making it simple to find dining options and pick up essentials. It's an excellent base for those who plan to explore the wider region, as I-44 provides direct routes to nearby cities.

    Couples looking for a comfortable and straightforward stay often appreciate the convenience of hotels in this commercial corridor.

    When is the best time to go to Duquesne?

    The best time to visit Duquesne, Missouri, is typically during the spring (April to June) and fall (September to October) months.

    These seasons offer pleasant weather with moderate temperatures and less humidity, making it comfortable for exploring the outdoors and enjoying local attractions. Spring brings blooming flora, while fall is known for its scenic foliage.

    Travelers looking for a quiet getaway will appreciate these shoulder seasons, as they generally see fewer crowds compared to the peak summer months.

    Can I cancel my hotel reservation on Expedia?

    You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Duquesne.

    How much is the nightly rate at a Duquesne hotel?

    Prices for hotels in Duquesne often vary, but you can find a great deal from $66 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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