1. La Quinta Inn & Suites by Wyndham Joplin

- Location: Joplin
- Guest rating: 9/10 (Wonderful, 1761 reviews)
- Price: $89 nightly, $101 total, Nov 23 - Nov 24, Total with taxes and fees
- Review: Great stay!!, by Lisa
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Check prices for these dates, December 14 – 15, 2026




















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The best area to stay in Duquesne is generally near the main commercial areas along Missouri Route 171 (MO-171) or Interstate 44 (I-44) for convenient access to amenities and regional travel.
For travelers prioritizing ease of access and modern conveniences, staying near the intersection of MO-171 and I-44 is the most practical choice. This area features several hotels, restaurants, and retail establishments, making it simple to find dining options and pick up essentials. It's an excellent base for those who plan to explore the wider region, as I-44 provides direct routes to nearby cities.
Couples looking for a comfortable and straightforward stay often appreciate the convenience of hotels in this commercial corridor.
The best time to visit Duquesne, Missouri, is typically during the spring (April to June) and fall (September to October) months.
These seasons offer pleasant weather with moderate temperatures and less humidity, making it comfortable for exploring the outdoors and enjoying local attractions. Spring brings blooming flora, while fall is known for its scenic foliage.
Travelers looking for a quiet getaway will appreciate these shoulder seasons, as they generally see fewer crowds compared to the peak summer months.
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Duquesne.
Prices for hotels in Duquesne often vary, but you can find a great deal from $66 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.