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Middlesex Vacation Rentals

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    Check prices for these dates, December 13 – 14, 2026

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    Our top choices for Middlesex vacation rentals

    1. Affordable Suites Wilson

    A multi-story hotel with a parking lot and a tree-lined street.

    2. Retreat near Raleigh: Pool Table, Grill & ADA Bath in Remodeled Home

    Interior

    3. Mountain Vibes • 3BR 2BA Near Raleigh

    A living room with a beige sofa, a coffee table, a TV, and a fireplace.

    4. country living and relaxing!

    A covered porch with a sofa, table, and chairs.

    5. Charming house w/WiFi and AC in tranquil Wilson,walking distance to brewmasters

    A compact kitchen with a built-in stove, a sink, and a microwave. There is a small countertop and a cabinet above the stove.

    6. Wilson second floor

    A kitchen with light blue cabinets, a white countertop, a black stove, and a stainless steel sink.

    7. Charming country retreat!

    A spacious living room with a large sofa, a fireplace, and a ceiling fan.

    8. Cozy cottage with sunset views in Wilson - pet friendly- sleeps 6

    A backyard with a covered patio, a white building, and string lights.

    9. Mom's house

    A living room with a dark blue sofa, a small armchair, a flat-screen TV mounted on the wall, a kitchen area with a stainless steel oven, and a patterned rug on the floor.

    10. Rosa's house

    A wooden sign with "AIRBNB PARKING A" on a porch.

    11. The Harriss

    A two-story building with large windows and a sign reading "HARRIS 1916".

    12. Petite Palace: Guest home in Louisburg, NC

    A two-story house with a front porch, a small attached garage, and a well-maintained lawn.

    13. Gamers & Disc Golfers Dream! Spacious 4BR Home

    Private kitchen

    14. Downtown Wake Forest Loft #2

    A kitchen with white cabinets, a refrigerator, a microwave, a stove, and a sink.

    15. 3-bedroom house in adorable Raleigh with cool AC, charm and pool access

    A modern kitchen with white cabinetry, stainless steel appliances, and a granite countertop.

    16. 2BD Haven Steps from DT Clayton

    A modern kitchen with stainless steel appliances, a central island with bar stools, and a dining area with a view of the outdoors.

    17. Comfy 2BD Abode Mins from DT Clayton | Pool | Gym

    A bedroom with a bed, a ceiling fan, a window with blinds, a bedside table, and a nightstand.

    18. Amelia’s Haven Includes Light Breakfast

    A cozy outdoor seating area with two wicker chairs, a small round table, and a decorative sign.

    19. Best of Both Worlds: Total Cottage Privacy AND only 0.5mi Walk Downtown!

    A modern kitchen with wooden cabinets, stainless steel appliances, and a view to the outside.

    20. Tranquil 2-bedroom mobile home with AC in Rocky Mount

    Private kitchen

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Top Middlesex Hotel Reviews

    Hampton Inn & Suites Wilson I-95

    A hotel lobby with a seating area, a bar, and a television mounted on the wall.

    Tru By Hilton Wilson

    A modern hotel lobby with a central reception desk, seating area, and a visible restaurant named 'TOP IT BRIO'.

    Holiday Inn Express Hotel & Suites Wilson - Hayes Place by IHG

    A modern dining area with a coffee station, multiple tables, and chairs.

    Hampton Inn by Hilton Wilson

    A spacious hotel lobby with a blue sofa, wooden chairs, and a dining area.

    Comfort Suites Wilson I-95

    A hotel lobby with seating areas, a reception desk, and a coffee station.

    Fairfield Inn & Suites by Marriott Wilson

    A modern hotel lobby with a long wooden reception desk, blue and beige seating, and geometric wall panels.

    Quality Inn Kenly I-95

    A motel with a covered entrance, multiple parking spaces, and a clear sky.

    Microtel Inn by Wyndham Wilson

    A hotel room with a bed, a desk, a chair, a window with curtains, a flat-screen TV mounted on the wall, and a wall-mounted lamp.

    Hampton Inn by Hilton Smithfield Selma

    An outdoor patio area with seating and a fireplace.

    Sleep Inn & Suites Smithfield near I-95

    A lobby with a reception desk, a sofa, a coffee table, and a chandelier.

    Homewood Suites by Hilton Rocky Mount

    An outdoor patio with stone walls, wicker furniture, a fire feature, and string lights.

    Tru By Hilton Smithfield I-95

    An outdoor seating area with a fire feature, a sofa, and a table.

    The Clayton Magnolia Inn

    A two-story house with a porch, a covered front entrance, and a number '507' on the steps.

    Holiday Inn Rocky Mount - US 64 by IHG

    A swimming pool with clear water, surrounded by tiled walls and large windows.

    Spark by Hilton Smithfield I-95

    A hotel with a modern design, featuring a covered entrance and a sign that reads "spark by Hilton."

    Affordable Suites Wilson

    A multi-story hotel with a parking lot and a tree-lined street.

    Find out more about Middlesex

    Everything you need to know about Middlesex vacation rentals

    Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Middlesex vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

    There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Middlesex vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

    Middlesex vacation rentals: An excellent choice for every season

    Whenever you want to travel, a warm welcome awaits you in Middlesex. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Middlesex in high season.

    Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $69 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

    How to find incredible deals on Middlesex rentals

    At Expedia, we put the best Middlesex vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

    To find some top Middlesex rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Middlesex vacation.

    If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Middlesex. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

    Frequently Asked Questions

    Are there vacation rentals in Middlesex?

    Yes, you can find vacation rentals close to well known sights in Middlesex, or you can select a secluded option if you want a relaxing place to stay.

    What are some of the best vacation home rentals that Middlesex has to offer?

    Updated 4-bedroom house with relaxing sunroom; minutes from downtown Raleigh.: This vacation home rental near Middlesex offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

    What’s there to see and do in Middlesex?

    Explore the area and family-friendly sights such as Flower's Crossroads Park, or get out into nature at a spot like Zeublon Community Center. In the larger area, you’ll find Nomaco Park and Zebulon Community Park.

    What’s a vacation rental in Middlesex like?

    A vacation rental is a private property where you can stay for a few weeks or just a few days in Middlesex. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll feel just like you're at home. If you're concerned about cleanliness, a vacation rental can offer a sense of security away from shared hotel elevators and bustling concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive choice for a family getaway.