Ortigia Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Ortigia Vacation
Reserving a tailor-made Ortigia vacation package is a superb way to become acquainted with this unique neighborhood. From its renowned sites to its little-known secrets, there's plenty to discover. Eager to do some sightseeing during your trip to Ortigia? Pencil in a visit to nearby attractions like Cathedral of Syracuse, Temple of Apollo and Museo Archeologico Regionale Paolo Orsi. Stop dreaming and start doing. When you're ready to book your next vacation to Ortigia, Expedia will help you get there.
Price found within the past 48 hours. Click for updated prices.
- Hotel Palladio
Aug 4 - Aug 12Hotel Palladio + Flight
Giardini Naxos7 nights9.0/10 - Wonderful (336 reviews)"Excellent breakfast set up to avoid food waste. Staff very friendly. Hotel - unique boutique style"Reviewed April 25, 2026Roundtrip • Los Angeles (LAX) - Reggio Calabria (REG)LAX - REG • 2 stops REG - LAX • 2 stops$2,329$1,731found 2 hours agoper traveler - BAY PALACE MAZZARO'
Jun 20 - Jul 2BAY PALACE MAZZARO' + Flight
Spisone11 nights7.6/10 - Good (51 reviews)"Bay Palace is situated close to the beach with easy access up to Taormina by cable car. The views from this hotel are stunning. "Reviewed October 8, 2025Roundtrip • Los Angeles (LAX) - Catania (CTA)LAX - CTA • 1 stop CTA - LAX • 1 stop$3,368$2,382found 11 hours agoper traveler - Eurostars Monte Tauro
Jun 27 - Jul 2Eurostars Monte Tauro + Flight
Taormina4 nights8.6/10 - Excellent (469 reviews)"Large room with beautiful view. Excellent range of food at breakfast. "Reviewed May 17, 2026Roundtrip • Atlanta (ATL) - Reggio Calabria (REG)ATL - REG • 2 stops REG - ATL • 2 stops$3,082$2,182found 13 hours agoper traveler - Mazzarò Sea Palace - The Leading Hotels of the World
Jun 20 - Jul 2Mazzarò Sea Palace - The Leading Hotels of the World + Flight
Mazzaro11 nights9.6/10 - Exceptional (299 reviews)"Stunning hotel, beautiful location and beach. Amazing place to stay in Taormina."Reviewed May 6, 2026Roundtrip • Los Angeles (LAX) - Catania (CTA)LAX - CTA • 1 stop CTA - LAX • 1 stop - Wellness & Spa Hotel Principe di Fitalia
Jun 26 - Jul 5Wellness & Spa Hotel Principe di Fitalia + Flight
Syracuse8 nights9.6/10 - Exceptional (94 reviews)"This was such a wonderful stay! Spotless beautiful property with friendly staff and delicious breakfast!!! Very impressed!"Reviewed October 19, 2025Roundtrip • New York (JFK) - Reggio Calabria (REG)JFK - REG • 1 stop REG - JFK • 1 stop$5,119$4,010found 1 day agoper traveler
Where to stay in Ortigia
Find the best Ortigia areas and neighborhoods for the activities you enjoy most. Learn more about Ortigia
Santa Lucia
1 out of top 10 points of interest in this area
4.5/5(27 area reviews)
Santa Lucia is noteworthy for its historic sites, and you can make a stop at top attractions like Porto Piccolo and Ionian Sea.
Ortigia Hotel Deals
Algila' Ortigia Charme Hotel
Via Vittorio Veneto 93 Syracuse SR
$340 nightly
The price is $385 total per night from May 29 to May 30
$385 total
May 29 - May 30
Total with taxes and fees
9.6/10 Exceptional! (957 reviews)
"Great stay at a very interesting property. We found the staff in the restaurant exceptionally helpful, and we think the chef is first-rate."
Reviewed on May 19, 2026
Grand Hotel Ortigia Siracusa
Viale Mazzini, 12 Syracuse SR
Fully refundableReserve now, pay when you stay
$287 nightly
The price is $327 total per night from May 24 to May 25
$327 total
May 24 - May 25
Total with taxes and fees
9/10 Wonderful! (593 reviews)
"We stayed here for two nights and were extremely disappointed, especially considering this is supposed to be a five star property. Our first night we were put in a room where the bathroom had a horrid smell that spread to the entire room. The room was also on the same floor as all the cleaning staff ..."
Reviewed on May 17, 2026
Ortea Palace Hotel, Sicily, Autograph Collection
Via Riva Nazario Sauro Syracuse SR
$507 nightly
The price is $569 total per night from May 23 to May 24
$569 total
May 23 - May 24
Total with taxes and fees
9.4/10 Exceptional! (264 reviews)
"The in-room WiFi wasn’t working and they said it wouldn’t be working. That the in-room was a third party and they had no control!! Out coffee table was about to fall apart. Maintenance did come to try and save it but they couldn’t. So we had to live with it for the duration of our stay. The bar was ..."
Reviewed on May 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Ortigia
Lungomare di Ortigia
You can take time to visit Lungomare di Ortigia during your travels to Syracuse. Wander the seaside in this culturally rich area.
Temple of Apollo
Discover over 2,000 years of history when you visit the oldest Doric temple in Sicily.
Cathedral of Syracuse
Learn about the local history of Syracuse with a stop at Cathedral of Syracuse. Wander the seaside in this culturally rich area.
Things to do
Siracusa: Ortygia Island Boat Tour with Grotto Visit
$29
per adult
Syracuse: Boat Tour with Captain Mirko, Snorkeling & Caves
$35
per adult
Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat
$47
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.