San Francisco Vacations from $618
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest San Francisco vacation packages
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $1,815, price is now $1,068 per person
$1,068
per person
Apr 19 - Apr 24
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (1,002 reviews)
The room had no window to the outside it instead had a large window into an interior hall.
Maid service was inconsistent. Breakfast was not a good value.
Reviewed on Feb 5, 2026
Playa Caracol Residences Vacation Rental
Price was $1,430, price is now $987 per person
$987
per person
Mar 27 - Apr 3
found 1 day ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
7.2/10 Good! (26 reviews)
Great, clean condo overlooking the pool and ocean. We didn't cook our meals, but used the restaurant on site.
Staff was friendly and professional.
Reviewed on Dec 7, 2025
Hotel Riu Plaza Panama
Bella Vista
Price was $1,107, price is now $765 per person
$765
per person
Apr 19 - Apr 24
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (4,515 reviews)
El hotel es bellísimo, tiene restaurantes,cafetería 24 horas, piscina .El servicio es excelente.El desayuno es de primera.Disfrute muchísimo mi estancia aquí.
Reviewed on Feb 11, 2026
Villa Botero By Casa Mojito B&B
Price was $1,358, price is now $944 per person
$944
per person
Mar 29 - Apr 4
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time.
Reviewed on Jan 22, 2026
Don't see what you're looking for?
See all available trips from Columbus to San Francisco
View all trips
San Francisco Hotel Deals
Hotel Gran David
Vía Interamericana Santiago Veraguas
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $81 total per night from Feb 12 to Feb 13
$81 total
Feb 12 - Feb 13
Total with taxes and fees
8.6/10 Excellent! (373 reviews)
Great Service! Clean and comfortable rooms. The owner and staff very friendly. I will come back again. Recommend it !
Reviewed on Feb 2, 2026
Hotel Mykonos Panama
Panamerican Highway Nuevo Santiago Veraguas
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $99 total per night from Feb 17 to Feb 18
$99 total
Feb 17 - Feb 18
Total with taxes and fees
HOTEL VISTA LAGO
Rincón Largo La Pena Santiago de Veraguas
$77 nightly
The price is $84 total per night from Feb 12 to Feb 13
$84 total
Feb 12 - Feb 13
Total with taxes and fees
9.2/10 Wonderful! (90 reviews)
Great atmosphere around the restaurant and pool. We found it very relaxing in an otherwise busy city. Restaurant makes good meals and the service is great.
Reviewed on Feb 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best San Francisco Vacation Packages
More vacations you might like
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
