Santa Isabel Vacations from $370

Book a Hotel + Flight or Car together to unlock savings

Your Santa Isabel Vacation

Say farewell to planning worries and hello to a Santa Isabel vacation package. With everything organized before you leave, you can focus on discovering every inch of this city, starting with Espino, which is great for hiking, nature and families. Make your trip to Santa Isabel even more fulfilling by including some sightseeing. Parque Ceremonial Indigena de Caguana, Parque Ceremonial Indigena Caguana and Parque Acuatico are among the popular attractions worth exploring. Expedia has what you need to escape the everyday. Tailor your vacation to Santa Isabel to match your travel style, whatever that may be!

The Latest Santa Isabel vacation packages

Price found within the past 48 hours. Click for updated prices.
Lazy Parrot Inn
Ola Boutique Hotel
Hotel Puerto Valdes
OLV Fifty Five - Adults Only
Coral by the Sea Hotel
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Discover the most popular places to visit in Santa Isabel

What to do in Santa Isabel

Santa Isabel Hotel Deals

Costa Bahia Hotel & Convention Center

Costa Bahia Hotel & Convention Center

3.5 out of 5
Exit 205 Road 127 Km 8.6, Guayanilla
$134 nightly
The price is $149 total per night from Nov 2 to Nov 3
$149 total
Nov 2 - Nov 3
Total with taxes and fees
8.8/10 Excellent! (1,809 reviews)
Our stay was very nice. The thing I didn’t like was the problem with the parking. They should have a separate area for guest who are staying at the hotel and have a separate area for guest to their casino.

Reviewed on Oct 24, 2025

Costa Bahia Hotel & Convention Center
Arecibo Inn

Arecibo Inn

3 out of 5
Road #2 km 67.2, Barrio Santana, Arecibo
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $96 total per night from Oct 29 to Oct 30
$96 total
Oct 29 - Oct 30
Total with taxes and fees
7.8/10 Good! (1,029 reviews)
Clean room and bathroom

Reviewed on Oct 22, 2025

Arecibo Inn
Hotel El Guajataca

Hotel El Guajataca

3.5 out of 5
Carretera 2 Km. 103.8, Barrio Terranova, Quebradillas
$98 nightly
The price is $107 total per night from Nov 11 to Nov 12
$107 total
Nov 11 - Nov 12
Total with taxes and fees
8.2/10 Very Good! (1,003 reviews)
Pool and bar pool excellent.

Reviewed on Oct 26, 2025

Hotel El Guajataca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel Vacation Packages

Santa Isabel Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Rafael Hernandez Airport (BQN)
Top Sights
Parque Ceremonial Indigena de Caguana, Parque Ceremonial Indigena Caguana and Batey Zipline Adventure

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Frequently asked questions

How much does a Santa Isabel vacation package cost?
You'll find cheap prices from $370 on Expedia for your Santa Isabel escape. However, factors like the hotel choice, length of stay and season will influence how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
April, July and October are great times to look for cheap Santa Isabel vacation packages. Opting to travel in less busy periods means you can usually find lower prices on accommodations and flights.
How many days is enough for Santa Isabel?
The ideal length of your Santa Isabel vacation depends on what you'd like to do and see. Usually, a few days to a week will give you enough time to visit all the leading attractions and discover some hidden spots along the way.
How to find the best Santa Isabel package deals?
Use Expedia's filters to help you find some great Santa Isabel package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or browse for Santa Isabel package deals in the low season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to book your vacation package as soon as possible.
Is it cheaper to book a Santa Isabel vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking accommodations and flights individually. Better still, you can tailor your Santa Isabel getaway to match your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our great deals to see how much you can save.
When to book a vacation package to Santa Isabel?
If you're planning an impromptu Santa Isabel adventure, check out our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can score incredible deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
If you're like us, you love discovering new places but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the cost of your Santa Isabel break across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.