Santa Isabel Vacations from $541
Book a Hotel + Flight or Car together to unlock savings
Your Santa Isabel Vacation
Say farewell to planning worries and hello to a Santa Isabel vacation package. With everything organized before you leave, you can focus on discovering every inch of this city, starting with Espino, which is great for hiking, nature and families. Make your trip to Santa Isabel even more fulfilling by including some sightseeing. Parque Ceremonial Indigena de Caguana, Parque Ceremonial Indigena Caguana and Parque Acuatico are among the popular attractions worth exploring. Expedia has what you need to escape the everyday. Tailor your vacation to Santa Isabel to match your travel style, whatever that may be!
The Latest Santa Isabel vacation packages
Price found within the past 48 hours. Click for updated prices.
Villa Azure Ocean Suites
Santurce
$2,503
per person
Nov 12 - Nov 16
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to San Juan (SJU)
10/10 Exceptional! (3 reviews)
We had such an amazing time at Villa Azure! Our group of 16 couldn’t get enough of the gorgeous ocean views, and the fact that the beach was just a short walk away was perfect. The house itself was super cozy and beautifully decorated—plenty of space for everyone but still felt like home. We spent hours relaxing by the pool and enjoying the outdoor area, which was perfect for hanging out together. We can’t wait to come back!
Reviewed on Oct 21, 2024
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See all available trips from Columbus to Santa Isabel
View all tripsWhat to do in Santa Isabel
Half-Day Center of Puerto Rico Cultural Tour
$85
per adult
100% of travellers recommend
Full Day Tour Window Cave and Hiking on the Beach
$150
per adult
Full Day Vamos Pa la Isla Southwest Experience
$240
per adult
100% of travellers recommend
Santa Isabel Hotel Deals
Costa Bahia Hotel & Convention Center
Exit 205 Road 127 Km 8.6 Guayanilla
$121 nightly
$134 total
Oct 6 - Oct 7
Total with taxes and fees
8.8/10 Excellent! (2,225 reviews)
"Good"
Reviewed on Oct 1, 2026
Hacienda Villa Sotomayor
Bo Garzas Adjuntas Adjuntas
Fully refundableReserve now, pay when you stay
$64 nightly
$79 total
Oct 6 - Oct 7
Total with taxes and fees
Hotel Vista Verde
Puerto Rico 368 Yauco Yauco
Fully refundableReserve now, pay when you stay
$106 nightly
$116 total
Oct 12 - Oct 13
Total with taxes and fees
8.6/10 Excellent! (305 reviews)
"100% recomendado. Volvería otra vez"
Reviewed on Sep 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Isabel Vacation Packages
Santa Isabel Essential Information
Language | Spanish |
|---|---|
Currency | U.S dollars |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Rafael Hernandez Airport (BQN) |
Top Sights | Parque Ceremonial Indigena de Caguana, Parque Ceremonial Indigena Caguana and Batey Zipline Adventure |
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Frequently asked questions
How much does a Santa Isabel vacation package cost?
You'll find cheap prices from $541 on Expedia for your Santa Isabel escape. However, factors like the hotel choice, length of stay and season will influence how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
April, July and October are great times to look for cheap Santa Isabel vacation packages. Opting to travel in less busy periods means you can usually find lower prices on accommodations and flights.
How many days is enough for Santa Isabel?
The ideal length of your Santa Isabel vacation depends on what you'd like to do and see. Usually, a few days to a week will give you enough time to visit all the leading attractions and discover some hidden spots along the way.
How to find the best Santa Isabel package deals?
Use Expedia's filters to help you find some great Santa Isabel package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or browse for Santa Isabel package deals in the low season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to book your vacation package as soon as possible.
Is it cheaper to book a Santa Isabel vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking accommodations and flights individually. Better still, you can tailor your Santa Isabel getaway to match your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our great deals to see how much you can save.
When to book a vacation package to Santa Isabel?
If you're planning an impromptu Santa Isabel adventure, check out our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can score incredible deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
If you're like us, you love discovering new places but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the cost of your Santa Isabel break across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.