Southern Region Vacations & Trips

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Your Southern Region Vacation

When adventure calls, answer it with a tailor-made vacation package to Southern Region. Wherever it is you're headed and whatever you have planned, prepare to discover a destination that'll make you truly feel alive. Your trip to Southern Region wouldn't be complete without spending some time in its best cities, starting with Blantyre. A couple of the top attractions here include Mandala House and Carlsberg Brewery. Zomba is another favorite city with Southern Region travelers. Visitors to this city enjoy Emperor's View and Williams Falls. Expedia has everything you need when it comes to organizing your Southern Region vacation. From flights and hotels, to activities and more, we know how to create a travel experience like no other.

Top destinations in Southern Region

My visit to Malawi was too brief, only a couple of days, and I had no time to sightsee. The Blantyre and Kamaze area are surrounded by mountains. I wish I could have seen more of the countryside. I loved this quaint little grocery store on the side of the highway.
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Blantyre

Blantyre

Southern Region Hotel Deals

Protea Hotel by Marriott Blantyre Ryalls

Protea Hotel by Marriott Blantyre Ryalls

4.5 out of 5
2 Hannover Avenue, Blantyre
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $161 total per night from Aug 22 to Aug 23
$161 total
Aug 22 - Aug 23
Total includes taxes and fees
8.8/10 Excellent! (140 reviews)
"Lovely old hotel with lots of character. Staff are polite and helpful"

Reviewed on Feb 14, 2025

Protea Hotel by Marriott Blantyre Ryalls
Mgoza Lodge

Mgoza Lodge

2.5 out of 5
Main Road, Lake Malawi National Park, Cape Maclear, Mangochi
$55 nightly
The price is $65 total per night from Aug 20 to Aug 21
$65 total
Aug 20 - Aug 21
Total includes taxes and fees
8.4/10 Very Good! (33 reviews)
"As advertised"

Reviewed on Apr 14, 2025

Mgoza Lodge
Casa Mia

Casa Mia

3 out of 5
Kabula Hill Road, Blantyre
8.4/10 Very Good! (113 reviews)
"It was a wonderful nite. Good wine, delicious cheese burger and wonderful wait staff"

Reviewed on Jul 17, 2025

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Casa Mia
See all 85 properties in Southern Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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All Inclusive Vacations
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Beach Vacations
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Kid Friendly Vacations

Discover the most popular places to visit in Southern Region

Monkey Bay Beach

Monkey Bay Beach

If a restful vacation is part of your travel plans, Monkey Bay Beach might be the perfect place to seek out during your trip to Mangochi. Take in the museums while you're in the area.

Monkey Bay Beach

University of Malawi

Explore the campus of University of Malawi, during your trip to Zomba. Discover the mountain views while you're in the area.

University of Malawi

Liwonde National Park

Explore the great outdoors at Liwonde National Park, a lovely green space in Liwonde.

Liwonde National Park

What to do in Southern Region

Southern Malawi Adventure 7Days/ 6 Nights

Southern Malawi Adventure 7Days/ 6 Nights

$4,663
per adult
Southern Malawi Adventure 7Days/ 6 Nights
Magic Christmas Tour in Blantyre

Enchanting Tour in Blantyre (Malawi)

$503
per traveler
Enchanting Tour in Blantyre (Malawi)
Hikers try climbing a rock on a tour

Zomba plateau Day Hike Tour

$160
per adult
Zomba plateau Day Hike Tour
See all activities in Southern Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.