Southern Region Vacations & Trips

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Your Southern Region Vacation

When adventure calls, answer it with a tailor-made vacation package to Southern Region. Wherever it is you're headed and whatever you have planned, prepare to discover a destination that'll make you truly feel alive. Your trip to Southern Region wouldn't be complete without spending some time in its best cities, starting with Blantyre. A couple of the top attractions here include Mandala House and Carlsberg Brewery. Zomba is another favorite city with Southern Region travelers. Visitors to this city enjoy Emperor's View and Williams Falls. Expedia has everything you need when it comes to organizing your Southern Region vacation. From flights and hotels, to activities and more, we know how to create a travel experience like no other.

Top destinations in Southern Region

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

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Southern Region Essential Information

Language
Chichewa
Currency
Malawian kwachas
Closest Airport
Chileka Intl. Airport (BLZ)
Top Sights
Lake Malawi National Park, Monkey Bay Beach and Liwonde National Park

Southern Region Hotel Deals

Protea Hotel by Marriott Blantyre Ryalls

Protea Hotel by Marriott Blantyre Ryalls

4.5 out of 5
2 Hannover Avenue Blantyre
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $162 total per night from Mar 6 to Mar 7
$162 total
Mar 6 - Mar 7
Total with taxes and fees
8.8/10 Excellent! (144 reviews)
Yes

Reviewed on Jan 24, 2026

Protea Hotel by Marriott Blantyre Ryalls
Serendib Suites & Conference Center

Serendib Suites & Conference Center

3.5 out of 5
Off Chilomoni Ring Road Blantyre
Fully refundableReserve now, pay when you stay
5.4/10 (6 reviews)
Friendly staff

Reviewed on Nov 1, 2025

Serendib Suites & Conference Center
Chinyonga Guesthouse

Chinyonga Guesthouse

3 out of 5
4 Yayola Street, Off Kenyatta Drive Blantyre
$38 nightly
The price is $45 total per night from Feb 27 to Feb 28
$45 total
Feb 27 - Feb 28
Total with taxes and fees
8.2/10 Very Good! (30 reviews)
so so lovely! 10/10 recommend

Reviewed on Jan 9, 2026

Chinyonga Guesthouse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Southern Region

What to do in Southern Region

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.