Southern Region Vacations & Trips

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Your Southern Region Vacation

When adventure calls, answer it with a tailor-made vacation package to Southern Region. Wherever it is you're headed and whatever you have planned, prepare to discover a destination that'll make you truly feel alive. Your trip to Southern Region wouldn't be complete without spending some time in its best cities, starting with Blantyre. A couple of the top attractions here include Mandala House and Carlsberg Brewery. Zomba is another favorite city with Southern Region travelers. Visitors to this city enjoy Emperor's View and Williams Falls. Expedia has everything you need when it comes to organizing your Southern Region vacation. From flights and hotels, to activities and more, we know how to create a travel experience like no other.

Top destinations in Southern Region

A cityscape at dusk with a prominent building in the center, surrounded by residential areas and a mountain in the background.

Blantyre

Blantyre
A person riding a camel on a beach with the sea in the background.

Mangochi

Mangochi
A large reservoir surrounded by forested hills.

Zomba

Zomba
A rocky shoreline with large boulders and sparse vegetation.

Cape Maclear

Cape Maclear
A mountain with lush green vegetation and a tea plantation in the foreground.

Chigumula

Chigumula
Four lion cubs on a dry, sandy terrain with sparse vegetation.

Liwonde

Liwonde

Find the Best Southern Region Vacation Packages

Southern Region Essential Information

Language
Chichewa
Currency
Malawian kwachas
Closest Airport
Chileka Intl. Airport (BLZ)
Top Sights
Lake Malawi National Park, Monkey Bay Beach and Liwonde National Park

Southern Region Hotel Deals

Protea Hotel by Marriott Blantyre Ryalls

Protea Hotel by Marriott Blantyre Ryalls

2 Hannover Avenue Blantyre
Fully refundableReserve now, pay when you stay
$147 nightly
$174 total
Sep 4 - Sep 5
Total with taxes and fees
8.8/10 Excellent! (151 reviews)
"The restaurant was excellent! The staff was friendly and so helpful when I arranged a dinner for 20 people. A special shoutout of thanks to Sanderson, the amazing gentleman who helped me plan the event!"

Reviewed on Aug 23, 2026

Protea Hotel by Marriott Blantyre Ryalls
Casa Mia

Casa Mia

Kabula Hill Road Blantyre
$69 nightly
$82 total
Aug 30 - Aug 31
Total with taxes and fees
Casa Mia
Anake Lodge

Anake Lodge

Chembe Village Cape Maclear Southern Region
$53 nightly
$64 total
Sep 6 - Sep 7
Total with taxes and fees
Anake Lodge
See all 107 properties in Southern Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southern Region attractions

Monkey Bay Beach

8.6/10 (4 reviews)
If a restful vacation is part of your travel plans, Monkey Bay Beach might be the perfect place to seek out during your trip to Mangochi. Take in the museums while you're in the area.
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Liwonde National Park

8.0/10 (1 review)
Explore the great outdoors at Liwonde National Park, a lovely green space in Liwonde.
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The Way of the Cross/ Njira ya Mtanda

7.4/10 (3 reviews)
You can take time to visit The Way of the Cross/ Njira ya Mtanda during your travels to Blantyre. Discover the area's mountain views and churches.
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Nkhudzi Bay Beach

9.0/10 (2 reviews)
Why not spend a carefree afternoon at Nkhudzi Bay Beach during your travels in Mangochi? Take in the museums while you're in the area.
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Mangochi Museum

You can spend time exploring the galleries in Mangochi Museum in Mangochi. Take in the museums while you're in the area.
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What to do in Southern Region

Hikers try climbing a rock on a tour

Zomba plateau Day Hike Tour

$160
per adult
Zomba plateau Day Hike Tour
See all activities in Southern Region
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.