Title: Eastern Panama Cheap Vacations 2026 | Expedia.com ![](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Eastern Panama Cheap Vacations ## Book a Cheap Hotel + Flight or Car together to unlock savings Photo by Nico Barner - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Top Cheap vacation packages in Eastern Panama Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $771 per person Apr 19 - Apr 24 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) The room was clean and the staff were extremely eager to accommodate. Reviewed on Feb 15, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight $1,092 per person Apr 19 - Apr 24 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Room was clean and comfortable. Staff was very friendly and helpful. Breakfast was very good Reviewed on Feb 15, 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco $925 per person May 13 - May 17 found 22 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) Nice hotel. Friendly staff Reviewed on Feb 9, 2026 ![Casa Mallet by Wynwood House](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Mallet by Wynwood House Casco Viejo Save 100% on your flight $2,106 per person Apr 4 - Apr 11 found 4 hours ago Roundtrip flight included New York (JFK) to Panama City (PTY) 9.8/10 Exceptional! (24 reviews) Beautiful apartment definitely recommend staying here if you are coming to Panama Reviewed on Nov 29, 2025 ![Hyatt Regency Panama City](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w3837h2557x3y3-241f7e7d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Regency Panama City Bella Vista $938 per person Apr 19 - Apr 24 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 10/10 Exceptional! (103 reviews) Room space and cleanliness, as well as the staff Reviewed on Feb 10, 2026 Don't see what you're looking for? See all available trips from Columbus to Eastern Panama [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-16/2026-03-23/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Cheap vacations in Eastern Panama Price found within the past 48 hours. Click for updated prices. ![Renaissance Panama City Hotel ](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/d8dfdd09_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Renaissance Panama City Hotel Bella Vista $709 per person Apr 19 - Apr 24 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (85 reviews) The room was super clean. The staff was really nice and helpful. If I had any questions they were able to answer them very quickly. Definitely recommend this hotel it’s really close to everything whether you’re walking or driving i will definitely stay here again Next time I visit Panama. Reviewed on Feb 3, 2026 ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $771 per person Apr 19 - Apr 24 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) The room was clean and the staff were extremely eager to accommodate. Reviewed on Feb 15, 2026 ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### JW Marriott Panama San Francisco $1,077 per person Apr 19 - Apr 24 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,003 reviews) Excelente este hotel, de los mejores que tiene Panama. Reviewed on Feb 16, 2026 Don't see what you're looking for? See all available trips from Columbus to Eastern Panama [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-16/2026-03-23/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Cheap vacations in Eastern Panama Price found within the past 48 hours. Click for updated prices. ![Yoo by Wynwood House](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/f526e4da_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Yoo by Wynwood House Calidonia $534 per person Mar 20 - Mar 23 found 1 day ago Roundtrip flight included Miami (MIA) to Panama City (PTY) 9.2/10 Wonderful! (5 reviews) Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone. Reviewed on Jul 26, 2025 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo $878 per person May 8 - May 11 found 1 day ago Roundtrip flight included New York (JFK) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Room was clean and comfortable. Staff was very friendly and helpful. Breakfast was very good Reviewed on Feb 15, 2026 ![Casa Mallet by Wynwood House](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Mallet by Wynwood House Casco Viejo $803 per person Mar 20 - Mar 23 found 8 hours ago Roundtrip flight included Miami (MIA) to Panama City (PTY) 9.8/10 Exceptional! (24 reviews) Beautiful apartment definitely recommend staying here if you are coming to Panama Reviewed on Nov 29, 2025 Don't see what you're looking for? See all available trips from Columbus to Eastern Panama [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-16/2026-03-23/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Cheap vacations in Eastern Panama Price found within the past 48 hours. Click for updated prices. ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites $639 per person May 13 - May 17 found 22 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 10/10 Exceptional! (1 review) Excellent apartment on a golf resort. 5 Star. Reviewed on Jan 28, 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco $925 per person May 13 - May 17 found 22 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) Nice hotel. Friendly staff Reviewed on Feb 9, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo $1,222 per person Apr 4 - Apr 8 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Room was clean and comfortable. Staff was very friendly and helpful. Breakfast was very good Reviewed on Feb 15, 2026 Don't see what you're looking for? See all available trips from Columbus to Eastern Panama [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-16/2026-03-23/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Find amazing cheap vacations in Eastern Panama #### How can I find budget-friendly Eastern Panama vacation packages on Expedia? Playing around with the easy-to-use search wizard is one of the best ways to find affordable Eastern Panama vacation packages on Expedia. Tap your dates in and it'll offer some of the cheapest Eastern Panama getaways within seconds. You can also use the maximum price filter to view deals within your budget. If you're traveling during peak season dates, it's a good idea to book early to snag some of the best offers. You may score irresistible [last-minute specials](https://www.expedia.com/lp/b/vacations/last-minute-deals) for travel in low season. #### How to find cheap last-minute Eastern Panama travel deals? On Expedia's [last-minute](https://www.expedia.com/lp/b/vacations/last-minute-deals) travel deals page, you'll encounter a plethora of special offers for late vacations to Eastern Panama. Remember, you're more likely to bag savings on last-minute travel during off-peak periods. Consider checking different departure dates, too. Expedia's nifty search tool lets you compare some of the best last-minute Eastern Panama vacation packages. The handy filters let you tailor your trip according to your preferences, including hotel star rating, amenities, and property location. #### When is the best time to visit Eastern Panama on a budget? For some of the cheapest vacation packages to Eastern Panama from $534, it's best to travel during low season dates. With fewer people traveling during these periods, flights and hotels usually have lower prices. It's also a good idea to avoid popular travel times. These include spring break, Thanksgiving, and other federal holidays. On Expedia, you'll encounter some of the best travel deals to Eastern Panama. Best of all, vacation [payment plans](https://www.expedia.com/lp/b/vacations/planning) mean you can spread the cost of your trip over 3, 6, or 12 months. #### Can I cancel my Eastern Panama vacation package booking? Yes, many of Expedia's cheap Eastern Panama getaway packages allow for free cancellation in case your plans change. Follow the easy steps to cancel by logging into your Expedia account and clicking on “Trips” page'. Keep in mind, though, that each vacation package has different cancellation policies, so be sure to look over them before booking. The good news is you'll clearly see this information on Expedia when you book. There's even a free cancellation search filter that lets you view flexible vacations to Eastern Panama. #### Why should I book my Eastern Panama vacation with Expedia? A multitude of exclusive travel deals you won't find anywhere else is one of the top reasons to book your cheap Eastern Panama vacation package with Expedia. And with one of the widest choices of flights and hotels available, you'll easily find the right trip for you. The handy search wizard and filters let you compare hundreds of great deals in seconds, too. It's not only the cheap prices either: Expedia's booking protection and 24/7 support give you peace of mind before and during your 2026 trip. #### How to find cheap Eastern Panama vacation packages on Expedia? When searching for budget vacations to Eastern Panama, look out for the green savings label. This indicates you've snagged a deal only available on Expedia. Another popular way of getting money off your 2026Eastern Panama vacation is by joining [One Key](https://www.expedia.com/welcome-one-key). Expedia's amazing reward program gives you access to hundreds of member-only discounts on select hotels. Keep a look out for the blue savings label in the search results. Best of all, One Key is free to join. #### Why should I book a package to Eastern Panama? You'll often snag package savings on your Eastern Panama vacation when bundling together your flights and accommodation. Expedia even shows you how much you're saving by booking a package. It's not just cheaper prices, either. Packages often have more flexible booking conditions, meaning you're more likely to get a refund in case your 2026 plans change. While booking flights and hotels separately usually requires full payment, Eastern Panama vacation packages often let you pay a small upfront deposit to confirm. #### How to plan a cheap vacation to Eastern Panama? Settling on your dates is usually the first step to planning an affordable Eastern Panama getaway. If you're traveling during peak season dates, it's a good idea to book your trip in advance. This way, you're more likely to bag early-bird deals. Don't rule out a [last-minute travel deal](https://www.expedia.com/lp/b/vacations/last-minute-deals) for low season dates, though. Once you've picked your dates, tap them into the search wizard to see some of the best Eastern Panama vacation package deals. Hop over to Expedia's [vacation planning page](https://www.expedia.com/lp/b/vacations/planning) for more tips for your dream vacation. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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](https://expedia.com/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[ Eastern Panama Vacations ](https://expedia.com/Eastern-Panama.d6246114.Destination-Travel-Guides) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app