Title: Visit Matlacha Isles: 2026 Matlacha Isles, Cape Coral Travel Guide | Expedia.com [Hotels in Matlacha Isles](https://expedia.com/Matlacha-Isles-Cape-Coral-Hotels.0-n553248635976471942-0.Travel-Guide-Filter-Hotels)[Flights to Cape Coral](https://expedia.com/Cheap-Flights-To-Cape-Coral.d6521.Travel-Guide-Flights)[Things to do in Cape Coral](https://expedia.com/Things-To-Do-In-Cape-Coral.d6521.Travel-Guide-Activities)[Car Rentals in Matlacha Isles](https://expedia.com/Car-Rentals-In-Matlacha-Isles.d553248635976471942.Car-Rental-Guide)[Matlacha Isles Vacations](https://expedia.com/Matlacha-Isles.d553248635976471942.Destination-Travel-Guides) # Matlacha Isles, FL ## Cape Coral ## Visit Matlacha Isles Things to do Hotels Where to stay [Cape Coral Travel Guide](https://expedia.com/Cape-Coral.dx6521) --- ### Popular places to visit ![A Cute diverse boy and little girl running and splashing together holding hands in the large swimming pool resort while on a family vacation](https://images.trvl-media.com/place/6127772/0aad041a-6663-4407-82d6-553835cd82af.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Sun Splash Water Park Enjoy the thrill rides with your kiddos at Sun Splash Water Park during your trip to Cape Coral. Stroll along the beautiful beaches or discover the beautiful sunsets in this family-friendly area. [](https://expedia.com/Sun-Splash-Water-Park-Hancock.d6127772.Vacation-Attraction) ![:)](https://images.trvl-media.com/place/685728292503277568/6cc05580-f728-4052-a19d-2c5a8cb21e7e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Four Mile Cove Ecological Preserve Enjoy the beautiful sunsets and explore Four Mile Cove Ecological Preserve, a lovely green space in Cape Coral. Amble around this family-friendly area's beautiful beaches or attend a baseball game. [](https://expedia.com/Four-Mile-Cove-Ecological-Preserve-Hancock.d6296172.Vacation-Attraction) ![It's a beautiful morning in Cape Coral Fl](https://images.trvl-media.com/place/6521/55394f3b-70d9-44ea-8582-99307146bd81.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Tarpon Point Explore the waterfront in Cape Coral with a trip to Tarpon Point. [](https://expedia.com/Tarpon-Point-Fort-Myers.d553248635976195802.Vacation-Attraction) ![St. Augustine, Florida. January 26 , 2019. Sailboat and Bridge of Lions in Florida's Historic Coast](https://images.trvl-media.com/place/553248621563219756/90daf548-01bf-4d03-b307-d2e8f6ca70b7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Dolphin Marina Explore the waterfront of Dolphin Marina and enjoy other activities such as boating in Cape Coral. Wander the beautiful beaches and seaside in this family-friendly area. [](https://expedia.com/Dolphin-Marina-Caloosahatchee.d553248621563219756.Vacation-Attraction) #### Cape Coral Yacht Club Beach Why not spend a lazy afternoon at Cape Coral Yacht Club Beach during your trip to Cape Coral? [](https://expedia.com/Cape-Coral-Yacht-Club-Beach-Caloosahatchee.d553248635983994300.Vacation-Attraction) #### Pine Island Shopping Center You can search for that perfect souvenir at Pine Island Shopping Center during your stay in North Fort Myers. Stroll along the marina or attend a baseball game in this family-friendly area. [](https://expedia.com/Pine-Island-Shopping-Center-Hancock.d553248621563219766.Vacation-Attraction) ### Things to do ![Fort Myers Beach Sunset and Dolphin Watching Cruise](https://mediaim.expedia.com/localexpert/49585125/64783586-41c3-41b7-833b-538357650a0d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Fort Myers Beach Sunset and Dolphin Watching Cruise $70 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/fort-myers-beach-sunset-and-dolphin-watching-cruise.a49585125.activity-details) ![Southwest Florida Sunset Sail](https://mediaim.expedia.com/localexpert/3146060/208129dd-2c36-4c94-bbae-6379e223335e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Southwest Florida Sunset Sail $70 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/southwest-florida-sunset-sail.a3146060.activity-details) ![Copacetic Day Sail](https://mediaim.expedia.com/localexpert/3146061/ce46a7d1-6271-4a2e-9229-41a28a522002.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Copacetic Day Sail $70 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/copacetic-day-sail.a3146061.activity-details) ![Marco Island: 10,000 Islands Shelling Boat Tour](https://mediaim.expedia.com/localexpert/4543608/25622f40-41be-4e23-abf9-56d25be94fc9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Marco Island: 10,000 Islands Shelling Boat Tour $100 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/marco-island-10.a4543608.activity-details) ![Dolphin Wildlife Cruise Fort Myers Beach](https://mediaim.expedia.com/localexpert/49515597/7ddf5e09-b4b4-4b06-b75b-dc221f49d5cd.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Dolphin Wildlife Cruise Fort Myers Beach $64 per adult [](https://expedia.com/things-to-do/dolphin-wildlife-cruise-fort-myers-beach.a49515597.activity-details) ![Dolphin and Sightseeing Tiki Cruise](https://mediaim.expedia.com/localexpert/46963437/b9695ee5-1948-4f45-9a2c-697f0e0f2655.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Fort Myers Beach Dolphin & Sightseeing Tour Refreshments Included $65 per adult [](https://expedia.com/things-to-do/fort-myers-beach-dolphin-sightseeing-tour-refreshments-included.a46963437.activity-details) [See all activities in Cape Coral](https://expedia.com/Things-To-Do-In-Cape-Coral.d6521.Travel-Guide-Activities) --- ## Matlacha Isles Hotel Deals ![Margaritaville Beach Resort Fort Myers ](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/09777b0c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Margaritaville Beach Resort Fort Myers 251 Crescent Street Fort Myers Beach FL $398 nightly $444 total Apr 14 - Apr 15 Total with taxes and fees Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ... 9/10 Wonderful! (1,945 reviews) Really well run …in the hotel and beach club. Food and drinks were great and not any more expensive than anywhere else nearby (surprisingly). Beach club had a great vibe like Vegas clubs but without the nonsense. Highly recommend Reviewed on Mar 14, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F14%2F2026&endDate=4%2F15%2F2026&selected=95126992&PinnedHotelID=95126992&HadPinnedHotel=true®ionId=553248635976471942) ![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/f97bdde8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sanibel Island Beach Resort 1231 Middle Gulf Dr Sanibel FL $342 nightly $379 total Apr 12 - Apr 13 Total with taxes and fees Book a stay at this beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ... 9.2/10 Wonderful! (1,681 reviews) Absolutely Reviewed on Mar 16, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=17298818&PinnedHotelID=17298818&HadPinnedHotel=true®ionId=553248635976471942) ![Baymont by Wyndham Fort Myers Central](https://images.trvl-media.com/lodging/1000000/30000/23400/23367/1235104b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Baymont by Wyndham Fort Myers Central 4850 S Cleveland Ave Fort Myers FL $85 nightly $95 total Apr 17 - Apr 18 Total with taxes and fees Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ... 6.8/10 (1,021 reviews) The room was dirty. Very dirty! The bathroom looked as if it had never been cleaned. The toilet did not work. There were no towels. Staff was not helpful. The place was very loud with dogs barking in the middle of the night. Do not recommend unless you want to get tetanus. Reviewed on Mar 17, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F17%2F2026&endDate=4%2F18%2F2026&selected=23367&PinnedHotelID=23367&HadPinnedHotel=true®ionId=553248635976471942) ![Lani Kai Beachfront Resort](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/9bc89705_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Lani Kai Beachfront Resort 1400 Estero Blvd Fort Myers Beach FL $277 nightly $309 total Apr 5 - Apr 6 Total with taxes and fees Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, 3 restaurants, and a beach locale. Popular attractions Key West Express and Crescent Beach ... 9/10 Wonderful! (1,316 reviews) The ocean view was beautiful it was perfect. The room was nice. Housekeeping needs to improve requested service three days in a row and never got any front desk was accommodating with sending up, clean towels, etc.. Bed was horrible. One of the most rude individuals I ever met in my life was the ... Reviewed on Mar 17, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=438796&PinnedHotelID=438796&HadPinnedHotel=true®ionId=553248635976471942) ![Hilton Garden Inn Ft Myers](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/8dde6ece_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Garden Inn Ft Myers 12600 University Dr Fort Myers FL $115 nightly $129 total Mar 29 - Mar 30 Total with taxes and fees Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ... 8.8/10 Excellent! (1,001 reviews) Great spot Reviewed on Mar 15, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F29%2F2026&endDate=3%2F30%2F2026&selected=848740&PinnedHotelID=848740&HadPinnedHotel=true®ionId=553248635976471942) ![Marriott Sanibel Harbour Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/0ef86cd3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Marriott Sanibel Harbour Resort & Spa 17260 Harbour Pointe Dr Fort Myers FL $380 nightly $424 total Apr 5 - Apr 6 Total with taxes and fees Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ... 8.4/10 Very Good! (1,013 reviews) Great place to stay! Reviewed on Mar 17, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=3079&PinnedHotelID=3079&HadPinnedHotel=true®ionId=553248635976471942) [See all 14,679 properties in Matlacha Isles](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F18%2F2026&endDate=3%2F19%2F2026®ionId=553248635976471942) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Matlacha Isles hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976471942&startDate=2026-03-17&endDate=2026-03-18)[Mar 17 - Mar 18](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976471942&startDate=2026-03-17&endDate=2026-03-18) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976471942&startDate=2026-03-18&endDate=2026-03-19)[Mar 18 - Mar 19](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976471942&startDate=2026-03-18&endDate=2026-03-19) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976471942&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)[Mar 20 - Mar 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976471942&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976471942&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976471942&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) --- ### Other neighborhoods around Matlacha Isles ![SW Cape Coral Florida Aerial](https://images.trvl-media.com/place/553248635976468828/ab2978cf-7af3-432d-9e68-31de54821ca4.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Trafalgar If you're spending some time in Trafalgar, Palmetto-Pine Country Club and Fellowship Park are top sights worth seeing. [](https://expedia.com/Fort-Myers-Trafalgar.dx553248635976468828) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Burnt Store Though Burnt Store might not have many top sights, you can venture to the surrounding area to see attractions like Coral Oaks Golf Course and Burnt Store Marina. [](https://expedia.com/Cape-Coral-Burnt-Store.dx553248635976481229) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Mariner While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area. [](https://expedia.com/Fort-Myers-Mariner.dx553248635976470523) ![Vögel an der Westküste Floridas](https://images.trvl-media.com/place/553248635976481346/540bd2c4-15b9-419c-b501-b4108c456646.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Pelican 4.5/5(46 area reviews) If you're spending some time in Pelican, Tarpon Point and Chabad Jewish Center are top sights worth seeing. [](https://expedia.com/Cape-Coral-Pelican.dx553248635976481346) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Peninsula Point While Peninsula Point might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Tarpon Point and Sanibel Harbour Beach. [](https://expedia.com/Fort-Myers-Peninsula-Point.dx553248635976471712) ![SW Cape Coral Florida Aerial](https://images.trvl-media.com/place/553248635976469803/b6aedb92-81ca-4c5f-a337-ccc6a35f7969.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Cape Harbour When in Cape Harbour, you can plan a visit to Tarpon Point and Cape Coral Yacht Club Beach, some noteworthy sights in the nearby area. [](https://expedia.com/Fort-Myers-Cape-Harbour.dx553248635976469803) [See our Where To Stay guide](https://expedia.com/Cape-Coral.dx6521.Where-To-Stay?rfrr=TG.LP.Dest.Neigh.Neighborhoods) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Matlacha Isles, FL ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app