Lafayette County Vacations & Trips

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Your Lafayette County Vacation

Whether you're coming for the cycling, or any of the other highlights this place has to offer, our Lafayette County vacation packages give you the freedom to go wherever your curiosity takes you. Get your trip to Lafayette County off to a flying start by making Mayo your first stop. This is a popular city with visitors from all over. Start packing your suitcase, because your Lafayette County vacation is only a few clicks away with Expedia.

Top destinations in Lafayette County

Find the Best Lafayette County Vacation Packages

Lafayette County Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Jacksonville Intl. Airport (JAX)
Top Sights
Lafayette Blue Springs State Park, Troy Spring State Park and Lafayette Blue Springs State Park

Lafayette County Hotel Deals

Suwannee River Rendezvous

Suwannee River Rendezvous

2.5 out of 5
828 NE Primrose Rd Mayo FL
$108 nightly
The price is $116 total per night from Jul 7 to Jul 8
$116 total
Jul 7 - Jul 8
Total with taxes and fees
8.8/10 Excellent! (32 reviews)
"The room has been renovated, but when they renovated the floor underneath, must not have been stable because the room is on the down slope, and there is a lot of soft spots in the floor. It was dusty and dirty. I had to actually clean before I would let my grandkids stay up in the room upstairs because ..."

Reviewed on Jun 14, 2026

Suwannee River Rendezvous
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Mayo FL
$82 nightly
The price is $87 total per night from Jul 7 to Jul 8
$87 total
Jul 7 - Jul 8
Total with taxes and fees
10/10 Exceptional! (13 reviews)
"Awesome place! Peaceful spot out in nature. Has all you need and is a great home base to go out and explore the area. Lots of cool springs and the Suwanee River nearby!"

Reviewed on Jun 8, 2026

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

2.5 out of 5
6694 Us Highway 129 Live Oak FL
Fully refundable
$102 nightly
The price is $112 total per night from Aug 2 to Aug 3
$112 total
Aug 2 - Aug 3
Total with taxes and fees
8.4/10 Very Good! (848 reviews)
"The tv didn’t work (heard someone else state that too). Phone didn’t work. Lighting sucked light in corner not plugged in and no lightbulb. Breakfast was great"

Reviewed on Jun 27, 2026

Holiday Inn Express & Suites Live Oak by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Lafayette County attractions

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.