A calm river surrounded by trees with Spanish moss, reflecting the clear blue sky.

Mayo Vacations from $300

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  • Your Mayo Vacation

    Experience the unique character and personality of Mayo with a customized Mayo vacation package. From its rural countryside to its spectacular views, you'll never have a dull moment in this city. If seeing the sights is on your to-do list during your trip to Mayo, check out major attractions such as Lafayette Blue Springs State Park. Don't put off exploring this destination any longer. Your perfect Mayo vacation is a couple of clicks away with Expedia.

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    Where to stay in and around Mayo

    Mayo, a charming market town in north Florida, offers a delightful blend of outdoor adventures and scenic beauty. Explore its inviting downtown district, perfect for family outings or romantic getaways, and immerse yourself in the natural wonders that surround this picturesque destination.

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    Day

    Families and nature enthusiasts looking for an outdoor getaway will find Day, Florida, to be an ideal base for their adventures. Here, you can explore the stunning Lafayette Blue Springs State Park, enjoy the serene Allen Mill Pond Spring, or unwind at the local park. Located in Mayo, Day provides easy access to these attractions, making it simple to dive into recreational and beach activities. Choosing Day for your stay ensures a memorable experience in a charming village setting.

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    A calm river surrounded by trees reflecting in the water.

    A calm river with trees reflecting the sunlight.

    A calm river with clear water, surrounded by dense trees and rocky banks.

    A clear blue pond surrounded by dense forest.

    Photo by Dr__Vlad

    A swampy area with a calm water body surrounded by various trees and vegetation.

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    O Brien

    Experience the charm of O Brien, an excellent hub for adventurous travelers eager to explore Florida's natural beauty. With attractions like the Suwannee River for outdoor fun, the scenic Troy Spring State Park, and the quaint Branford Public Library, O Brien offers a perfect blend of adventure and relaxation. It’s about a 14-mile drive from Mayo, making it easy to access. Choosing O Brien for your stay ensures a memorable getaway filled with nature and excitement.

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    View properties in map for Dowling Park

    Dowling Park

    If you are a nature-loving family traveler, look no further than Dowling Park, a charming village renowned for its outdoor adventure and scenic beauty. Visitors can explore the breathtaking Lafayette Blue Springs State Park, enjoy the serene waters of Allen Mill Pond Spring, and discover the historic Ghost Town of Ellaville. With its peak visitor seasons in April, July, and September, Dowling Park is a delightful retreat, located about 14 miles from Mayo, making it an excellent choice for your vacation stay.

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    View properties in map for Alton

    Alton

    Alton stands out as a prime spot for travelers seeking family-friendly adventures in nature. This charming village offers access to beautiful outdoor experiences, including the scenic Wes Skiles Peacock Springs State Park, the tranquil river nearby, and the community-focused Veteran's Memorial Park of Mayo. Located in Mayo, Alton provides easy transit options for exploring these attractions. With its inviting atmosphere and appealing amenities, choosing Alton for your stay ensures a memorable vacation experience.

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    Mcalpin

    Travelers visiting the area often choose Mcalpin, especially families and nature enthusiasts seeking a budget-friendly getaway. This charming city offers easy access to the scenic Suwannee River, the beautiful Troy Spring State Park, and the inviting Baker Park, ensuring plenty of outdoor adventures. With moderately seasonal visitor numbers peaking in January and September to October, Mcalpin provides a vibrant atmosphere. Located about 15 miles from Mayo, Mcalpin is a smart choice for your next vacation, combining adventure with affordability.

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    Discover the most popular places to visit in Mayo

    Lafayette Blue Springs State Park

    Rating: 8.0/10 (6 reviews)

    Dive into this first-magnitude spring's crystal-clear waters flowing beneath a natural limestone bridge. Explore underwater caves or paddle to the iconic Suwannee River amid moss-draped oaks.

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    Perry Spring

    Perry Spring offers crystal-clear 72-degree waters where you can swim from a jumping platform into the Suwannee River. Relax at the covered pavilion with fire pit or lounge on the river deck with floating dock.

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    Lafayette County Library

    This welcoming community hub offers books, e-books, and resources for all ages. Enjoy free Wi-Fi, participate in book clubs, or attend special seasonal programs that promote literacy and community engagement.

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    Allen Mill Pond Spring

    This historic second-magnitude spring flows crystal-clear over ancient limestone beneath a canopy of cypress trees. Winter visits offer the best views of the old mill remnants when vegetation thins.

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    Veteran's Memorial Park of Mayo

    This peaceful memorial park honors veterans with thoughtful monuments and landscaped grounds. Visitors can reflect on service and sacrifice while enjoying the serene atmosphere.

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    Mayo Hotel Deals

    Cindys Motel

    A bedroom with a bed, a desk, a chair, and a ceiling fan.
    • Address: 487 W Main St, Mayo, FL, 32066, US
    • Location: 0.4 mi from Mayo
    • Star rating: 2.5/5
    • Guest rating: 8.8/10 (Excellent, 142 reviews)
    • Price: $90 nightly, $96 total, Nov 17 - Nov 18, Total with taxes and fees
    • Review: It was a clean room. We could park outside our room door.

    Suwannee River Rendezvous

    An aerial view of a campground with RVs, a swimming pool, and tennis courts.
    • Address: 828 NE Primrose Rd, Mayo, FL, 32066, US
    • Location: 5.2 mi from Mayo
    • Star rating: 2.5/5
    • Guest rating: 8.6/10 (Excellent, 34 reviews)
    • Price: $123 nightly, $131 total, Nov 17 - Nov 18, Total with taxes and fees
    • Review: "Traveling for a family event in the area. Staff was ok. Room was barely adequate, very run down. Tub wasnt the cleanest and very dingy and old. What was horrible was the room next to me had two large dogs who barked alot and the occupants came in after midnight they were extremely loud, dogs barking, yelling, banging doors it kept me up most of the night both nights. Then I attempted to have breakfast on Saturday and they were out of mostly everything at 9:15 They opened at 9. Would not stay...

    Quality Inn & Suites Live Oak I-10 Exit 283

    A hotel room with two beds, a desk, a chair, a lamp, and a view of the outdoors.
    • Address: 6819 Us Highway 129, Live Oak, FL, 32060, US
    • Location: 21.7 mi from Mayo
    • Star rating: 2.5/5
    • Guest rating: 7/10 (Good, 600 reviews)
    • Price: $84 nightly, $92 total, Nov 22 - Nov 23, Total with taxes and fees
    • Review: Everything good

    Holiday Inn Express & Suites Live Oak by IHG

    A buffet with various food items, including omelets and baked goods, served in metal containers.
    • Address: 6694 Us Highway 129, Live Oak, FL, 32060, US
    • Location: 22.8 mi from Mayo
    • Star rating: 2.5/5
    • Guest rating: 8.4/10 (Very good, 901 reviews)
    • Price: $99 nightly, $109 total, Dec 13 - Dec 14, Total with taxes and fees
    • Review: Nice place

    Royal Inn Motel

    A hotel room with a large bed, a sofa, a desk, and a lamp.
    • Address: 1829 South Byron Bulter Parkway, Perry, FL, 32348, US
    • Location: 24.9 mi from Mayo
    • Star rating: 2/5
    • Guest rating: 8.8/10 (Excellent, 1006 reviews)
    • Price: $79 nightly, $88 total, Nov 13 - Nov 14, Total with taxes and fees
    • Review: Nice room at an excellent price. Perfect for a restful stop while traveling. Not crowded when we were there, so it was nice and quiet. No frills, but a good clean room with good beds.

    Hampton Inn Perry

    A modern interior with a sofa, chairs, a small table, and a kitchen area.
    • Address: 2399 S Byron Butler Pkwy, Perry, FL, 32348, US
    • Location: 24.2 mi from Mayo
    • Star rating: 2.5/5
    • Guest rating: 8.6/10 (Excellent, 797 reviews)
    • Price: $118 nightly, $130 total, Dec 13 - Dec 14, Total with taxes and fees

    Econo Lodge Live Oak

    A hotel reception area with a reception desk, seating area, and a view of the parking lot.
    • Address: 6811 N Us 129 & I 10, Live Oak, FL, 32060, US
    • Location: 22.6 mi from Mayo
    • Star rating: 2/5
    • Guest rating: 7/10 (Good, 327 reviews)
    • Price: $73 nightly, $80 total, Nov 15 - Nov 16, Total with taxes and fees

    Days Inn by Wyndham Madison

    A hotel room with two beds, a desk, and a chair. There are two wall-mounted lamps and a painting above the beds.
    • Address: 6160 South State Road 53, Madison, FL, 32340, US
    • Location: 26.5 mi from Mayo
    • Star rating: 2/5
    • Guest rating: 7/10 (Good, 651 reviews)
    • Price: $92 nightly, $104 total, Nov 15 - Nov 16, Total with taxes and fees

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Frequently Asked Questions

    What's the best vacation package for Mayo?

    For travelers seeking a Mayo vacation package focused on value, or those preferring an independent stay, Cindys Motel is a strong option. Rated 8.8 out of 10, this motel provides amenities like a kitchenette and free WiFi, making it convenient for preparing your own meals. Travelers frequently praise its clean rooms and great staff.


    Families and outdoor enthusiasts looking to explore Mayo's natural attractions will find a package with a stay at Cindys Motel well-suited. It's located about 6 miles from Lafayette Blue Springs State Park, and its kitchenette can be particularly useful for family trips. Guests often highlight the clean rooms and helpful staff.


    If you're planning a Mayo vacation package and traveling with pets, Cindys Motel is a pet-friendly choice. This property, rated 8.8 out of 10, offers comfortable accommodations with air conditioning and free WiFi, with guests consistently noting the clean rooms and great staff.

    How can I save money on a Mayo vacation package?

    When you bundle, you can save up to 30%*. To save money on a Mayo package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.

    What are the top things to do in Mayo?

    A Mayo vacation offers plenty of outdoor and nature-focused activities, from exploring natural springs to enjoying family-friendly attractions:


    Browse and book things to do in Mayo on Expedia.

    Do you need to rent a car in Mayo, or is public transport enough?

    For Mayo vacation packages with flights, a rental car is highly recommended for exploring the area. As an outdoor and nature destination outside a major city, Mayo has many attractions that are spread out. For instance, natural springs like Lafayette Blue Springs State Park are about 6 miles away, and family attractions like Wild Adventures are about 19 miles from central Mayo. While you can fly into JAX-Jacksonville Intl. Airport (JAX), which is about 94 miles from Mayo, a car provides the flexibility to visit these natural attractions and other points of interest at your own pace.

    Are Mayo vacation package hotels conveniently located?

    Mayo vacation package hotels offer convenient access to the town center and nearby natural attractions. For example, Cindys Motel, rated 8.8 out of 10 by travelers, is located about a 10-minute walk from central Mayo. This central location makes it easy to explore the local area and access the region's outdoor activities.

    Can I change or cancel my Mayo vacation package if my plans change?

    Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.

    Do One Key members get extra savings when booking Mayo vacation packages?

    Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.

    Does Expedia offer Book Now, Pay Later Mayo vacation packages?

    Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Mayo vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.

    How do I find last-minute vacation packages to Mayo?

    To find last-minute vacation packages to Mayo, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.

    How does free cancellation work on Mayo vacation packages?

    Free cancellation on a Mayo vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.

    Is it cheaper to book a Mayo vacation as a package or separately?

    Booking flights and hotels together can unlock lower overall prices. Better still, you can tailor your Mayo getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.

    Why should I book my Mayo vacation package with Expedia?

    Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

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    * Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.