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Mayo Vacation Packages

Welcome to Mayo! This destination is set in Northeast Florida, an area popular for its pleasant beaches, wetlands and sandy beaches.

Save Time and Money with a Mayo Package Deal

Buy a hotel and flight package via Expedia and earn some savings. This is one of the easiest ways to save. You just pick your flights and your preferred hotel and combine them together in one package deal. During your stay in Mayo, spoil yourself with your extra cash.

Book your package and save up to $583!

With roughly 400 partner airlines and 321,000 worldwide hotels that you can choose from on our comprehensive database, your dream vacation can become a reality.

The great deals at Expedia will make your vacation so much fun. What are you waiting for?

Almost all hotel reservations can be cancelled with no hidden fees from us.

Mayo Vacation Packages

From Mayo, Tallahassee is roughly 70 miles to the northwest, while Jacksonville is around 95 miles east.

If you want to take a walk on the wild side of life, check out at least one of the region's natural areas. Steinhatchee Falls is located 18 miles away from Mayo, while Ichetucknee Springs State Park lies 25 miles away.

Two interesting locations worthy of a visit near Mayo are Dowling Park (16 miles to the north) and O Brien (16 miles to the east).

Approximately 35 miles to the northwest of Mayo is Madison, a regional center which is home to Yogi Bear's Jellystone Park, Treasures of Madison County and Lake Frances Recreation Area. Four Freedoms Monument and North Florida Community College are some more places if you have enough time.

Head outside and get active! You can try hiking and horse riding.

It's pretty difficult to honk your horn in a traffic jam after an afternoon spent shore fishing. Wildlife watching is another pleasant way to kick back and relax in the region.

For those who are just as happy in the water as on land, this is the perfect place for you. Swimming is popular with the locals, and so is surfing.

Take in some local culture by spending some time at some of the region's inspiring history museums.

Would you like a day out in the open air? Organize an excursion to one of the region's lighthouses.

If you want to truly understand Northeast Florida, take your time to stop at its bars, cafés and restaurants.

There's nothing like local goods. You'll soon find out that grouper and barbecue ribs are well utilized here.

The 4th of July is when the entire country will mark Independence Day. There's sure to be plenty of festivities taking place if you're vacationing at that time.

You don't have to worry about missing your flight. Just be sure to remember that the closest airport is 55 miles to the north.

*Savings based on all vacation package bookings with Flight + Hotel on Expedia.com from January through December 2017, as compared to price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.


Top Hotel Deals

See all 31 Properties in Mayo
Days Inn by Wyndham Madison $59
Days Inn by Wyndham Madison

Days Inn by Wyndham Madison

6160 South State Road 53, Madison
     
    3.6
    of 5, from 199 reviews
    2.0 out of 5.0

    Situated in Madison, this motel is within 6 mi (10 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North Florida Community College is 6.6 mi (10.6 km) away.

    Super 8 by Wyndham Madison $57
    Super 8 by Wyndham Madison

    Super 8 by Wyndham Madison

    6246 State Rd. 53 South, Madison
       
      3.7
      of 5, from 193 reviews
      2.0 out of 5.0

      Situated in Madison, this motel is within 6 mi (10 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North Florida Community College is 6.8 mi (11 km) away.

      Steinhatchee River Inn
      Steinhatchee River Inn

      Steinhatchee River Inn

      1111 Riverside Drive, Steinhatchee
         
        4.5
        of 5, from 55 reviews
        2.0 out of 5.0

        Situated on a river, this motel is within 1 mi (2 km) of Sea Hag Marina and Steinhatchee Public Boat Ramp. Steinhatchee Falls and Hagen Cove are also within 9 mi (15 km).

        Best Western Plus Madison Inn $89
        Best Western Plus Madison Inn

        Best Western Plus Madison Inn

        167 SE Bandit Street, Madison
           
          3.9
          of 5, from 152 reviews
          2.5 out of 5.0

          Situated in a rural location, this hotel is within 9 mi (15 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North Florida Community College is 6.9 mi (11.1 km) away.

          Royal Inn Motel $46
          Royal Inn Motel

          Royal Inn Motel

          1829 South Byron Bulter Parkway, Perry
             
            4.1
            of 5, from 169 reviews
            2.0 out of 5.0

            Situated in Perry, this motel is within 2 mi (3 km) of Perry Train Depot, Doctors Memorial Hospital, and Taylor County Historical Society. Forest Capital Museum State Park and Taylor County Sports Complex are also within 3 mi (5 km).

            Quality Inn Live Oak $80
            Quality Inn Live Oak

            Quality Inn Live Oak

            6819 Us Highway 129, Live Oak
               
              3.5
              of 5, from 140 reviews
              2.5 out of 5.0

              Located in the heart of Live Oak, this motel is 1.3 mi (2.2 km) from Suwannee County Historical Museum and within 6 mi (10 km) of First Federal Sportsplex and Baker Park. Spirit of the Suwannee Music Park and Suwannee Canoe Outpost are also within 9 mi (15 km).

              Deerwood Inn and Madison Campground
              Deerwood Inn and Madison Campground

              Deerwood Inn and Madison Campground

              155 S.W. Old St Augustine Road, Madison
                 
                3.2
                of 5, from 76 reviews
                2.0 out of 5.0

                Situated in Madison, this motel is within 9 mi (15 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North Florida Community College is 7.4 mi (11.9 km) away.

                Holiday Inn Express Hotel & Suites LIVE OAK $112
                Holiday Inn Express Hotel & Suites LIVE OAK

                Holiday Inn Express Hotel & Suites LIVE OAK

                6694 Us Highway 129, Live Oak
                   
                  4.0
                  of 5, from 194 reviews
                  2.5 out of 5.0

                  Situated in a rural location, this hotel is 2.4 mi (3.9 km) from Suwannee County Historical Museum and within 6 mi (10 km) of Spirit of the Suwannee Music Park and Suwannee Canoe Outpost. First Federal Sportsplex and Baker Park are also within 12 mi (20 km).