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See all 30 Hotels in Mayo
Holiday Inn Express Hotel & Suites LIVE OAK

Holiday Inn Express Hotel & Suites LIVE OAK

6694 Us Highway 129, Live Oak
of 5, from 179 reviews
2.5 out of 5.0

Situated in a rural location, this hotel is 2.4 mi (3.9 km) from Suwannee County Historical Museum and within 6 mi (10 km) of Spirit of the Suwannee Music Park and Suwannee Canoe Outpost. First Federal Sportsplex and Baker Park are also within 12 mi (20 km).

Best Western Plus Madison Inn

Best Western Plus Madison Inn

167 SE Bandit Street, Madison
of 5, from 139 reviews
2.5 out of 5.0

Situated in Madison, this hotel is within 6 mi (10 km) of Lake Frances Recreation Area, Treasures of Madison County, and Four Freedoms Monument. North Florida Community College is 6.9 mi (11.1 km) away.

Royal Inn Motel

Royal Inn Motel

1829 South Byron Bulter Parkway, Perry
of 5, from 149 reviews
2.0 out of 5.0

Situated in Perry, this motel is within 2 mi (3 km) of Perry Train Depot, Doctors Memorial Hospital, and Taylor County Historical Society. Forest Capital Museum State Park and Taylor County Sports Complex are also within 3 mi (5 km).

Holiday Inn Express Hotel & Suites PERRY

Holiday Inn Express Hotel & Suites PERRY

601 Everett Way, Perry
of 5, from 255 reviews
2.5 out of 5.0

Situated in Perry, this hotel is within 12 mi (20 km) of Forest Capital Museum State Park, Perry Train Depot, and Taylor County Historical Society. Doctors Memorial Hospital is 11.8 mi (19.1 km) away.

Top Deals on Flights

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.


Welcome to Mayo! This destination is set in Northeast Florida, an area popular for its pleasant beaches, wetlands and sandy beaches.

Packages in Mayo

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Travelers who grab deals can save as much as $603.

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For Mayo getaways, you will have a difficult time finding anything more cost-effective than the prices at Expedia.

Almost all hotel bookings can be changed without any additional charges from us.

Mayo Vacation Packages

From Mayo, Tallahassee is roughly 70 miles to the northwest, while Jacksonville is around 95 miles east.

If you want to take a walk on the wild side of life, check out at least one of the region's natural areas. Steinhatchee Falls is located 18 miles away from Mayo, while Ichetucknee Springs State Park lies 25 miles away.

Two interesting locations worthy of a visit near Mayo are Dowling Park (16 miles to the north) and O Brien (16 miles to the east).

Approximately 35 miles to the northwest of Mayo is Madison, a regional center which is home to Yogi Bear's Jellystone Park, Treasures of Madison County and Lake Frances Recreation Area. Four Freedoms Monument and North Florida Community College are some more places if you have enough time.

Head outside and get active! You can try hiking and horse riding.

It's pretty difficult to honk your horn in a traffic jam after an afternoon spent shore fishing. Wildlife watching is another pleasant way to kick back and relax in the region.

For those who are just as happy in the water as on land, this is the perfect place for you. Swimming is popular with the locals, and so is surfing.

Take in some local culture by spending some time at some of the region's inspiring history museums.

Would you like a day out in the open air? Organize an excursion to one of the region's lighthouses.

If you want to truly understand Northeast Florida, take your time to stop at its bars, cafés and restaurants.

There's nothing like local goods. You'll soon find out that grouper and barbecue ribs are well utilized here.

The 4th of July is when the entire country will mark Independence Day. There's sure to be plenty of festivities taking place if you're vacationing at that time.

You don't have to worry about missing your flight. Just be sure to remember that the closest airport is 55 miles to the north.