Mayo Vacations

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Your Mayo Vacation

Experience the unique character and personality of Mayo with a customized Mayo vacation package. From its rural countryside to its spectacular views, you'll never have a dull moment in this city. If seeing the sights is on your to-do list during your trip to Mayo, check out major attractions such as Lafayette Blue Springs State Park. Don't put off exploring this destination any longer. Your perfect Mayo vacation is a couple of clicks away with Expedia.

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Mayo Hotel Deals

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Mayo FL
$64 nightly
The price is $67 total per night from Mar 13 to Mar 14
$67 total
Mar 13 - Mar 14
Total with taxes and fees
9.8/10 Exceptional! (6 reviews)
Nice and pet friendly

Reviewed on Mar 7, 2026

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Cindys Motel

Cindys Motel

2.5 out of 5
487 W Main St Mayo FL
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $105 total per night from Apr 7 to Apr 8
$105 total
Apr 7 - Apr 8
Total with taxes and fees
8.8/10 Excellent! (130 reviews)
Easy parking. Friendly staff. We extended our stay and had to switch rooms. The 1st kingsize bad was great. But when we changed rooms the queen size bed sagged in the middle.

Reviewed on Mar 11, 2026

Cindys Motel
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Mayo FL
$82 nightly
The price is $86 total per night from Mar 24 to Mar 25
$86 total
Mar 24 - Mar 25
Total with taxes and fees
9.8/10 Exceptional! (9 reviews)
Extremely pet friendly & the cabin was warm and cozy even on cold nights. Be prepared for a short walk to the shared restroom to use the toilet and shower.

Reviewed on Jan 2, 2026

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
See all 470 properties in Mayo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mayo Vacation Packages

Mayo Essential Information

Language
English
Currency
U.S dollars
Population
1,250
Max Temp Winter
65ºF
Max Temp Summer
90ºF
Top Sights
Lafayette Blue Springs State Park and Troy Spring State Park

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Frequently asked questions

How much does a Mayo vacation package cost?
You'll find cheap prices on Expedia for your Mayo break. However, a range of factors like the hotel choice, length of stay and season will determine how much your vacation to Mayo costs.
What are the cheapest months to go to Mayo?
February, June and November are great times to search for cheap Mayo vacation packages. Traveling in less busy periods means you can typically find better prices on flights and hotels.
How many days is enough for Mayo?
With a well-organized travel plan, you can easily tick off the main Mayo attractions in a few days. But if you'd like to explore off the beaten track or go on day trips, consider booking your Mayo vacation for longer.
How to find the best Mayo package deals?
Use Expedia's handy filters to help you find some tempting Mayo package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your trip for midweek, or browse for Mayo package deals in the off-season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Mayo vacation as a package?
You can enjoy significant savings on your Mayo retreat by booking a personalized vacation package. Check the "Package" heading, then enter your destination and travel dates to see the best airfares and hotel prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Mayo?
If you've got your Mayo travel dates finalized, book as early as you can to bag some terrific deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spontaneous adventures? Our last-minute deals are perfect for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Mayo vacation packages?
Set off on your dream trip to Mayo with help from Expedia's Book Now, Pay Later vacations. No need to save like crazy or hold off until the next payday — we've teamed up with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans let you spread the total cost across 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to stick to your budget and snap up cheap deals while they last.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.