Mayo Vacations from $472
Book a Hotel + Flight or Car together to unlock savings
Your Mayo Vacation
Experience the unique character and personality of Mayo with a customized Mayo vacation package. From its rural countryside to its spectacular views, you'll never have a dull moment in this city. If seeing the sights is on your to-do list during your trip to Mayo, check out major attractions such as Lafayette Blue Springs State Park. Don't put off exploring this destination any longer. Your perfect Mayo vacation is a couple of clicks away with Expedia.
The Latest Mayo vacation packages
Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham Valdosta
$564
per person
Sep 22 - Sep 25
found 16 hours ago
Roundtrip non-stop flight included
Greenville (GSP) to Valdosta (VLD)
9.4/10 Exceptional! (2,113 reviews)
Large rooms and lobby/breakfast area are very clean, staff is nice, plenty of parking. Quiet despite being near Interstate, would definitely stay here again.
Reviewed on Aug 17, 2026
Stay near popular Mayo attractions
Lafayette Blue Springs State Park
8.0/10 (6 reviews)
Dive into this first-magnitude spring's crystal-clear waters flowing beneath a natural limestone bridge. Explore underwater caves or paddle to the iconic Suwannee River amid moss-draped oaks.
Perry Spring
Perry Spring offers crystal-clear 72-degree waters where you can swim from a jumping platform into the Suwannee River. Relax at the covered pavilion with fire pit or lounge on the river deck with floating dock.
Lafayette County Library
This welcoming community hub offers books, e-books, and resources for all ages. Enjoy free Wi-Fi, participate in book clubs, or attend special seasonal programs that promote literacy and community engagement.
Allen Mill Pond Spring
This historic second-magnitude spring flows crystal-clear over ancient limestone beneath a canopy of cypress trees. Winter visits offer the best views of the old mill remnants when vegetation thins.
Veteran's Memorial Park of Mayo
This peaceful memorial park honors veterans with thoughtful monuments and landscaped grounds. Visitors can reflect on service and sacrifice while enjoying the serene atmosphere.
Mayo Hotel Deals
Cindys Motel
487 W Main St Mayo FL
Fully refundableReserve now, pay when you stay
$90 nightly
$96 total
Aug 23 - Aug 24
Total with taxes and fees
Suwannee River Rendezvous
828 NE Primrose Rd Mayo FL
$123 nightly
$131 total
Aug 18 - Aug 19
Total with taxes and fees
8.6/10 Excellent! (33 reviews)
"Traveling for a family event in the area. Staff was ok. Room was barely adequate, very run down. Tub wasnt the cleanest and very dingy and old. What was horrible was the room next to me had two large dogs who barked alot and the occupants came in after midnight they were extremely loud, dogs barking, ..."
Reviewed on Jul 12, 2026
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Mayo FL
$79 nightly
$83 total
Aug 25 - Aug 26
Total with taxes and fees
10/10 Exceptional! (15 reviews)
"Great experiences!"
Reviewed on Aug 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Mayo Vacation Packages
Mayo Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Population | 1,250 |
Max Temp Winter | 65ºF |
Max Temp Summer | 90ºF |
Top Sights | Lafayette Blue Springs State Park and Troy Spring State Park |
More vacations you might like
Frequently asked questions
How much does a Mayo vacation package cost?
You'll find cheap prices from $472 on Expedia for your Mayo break. However, a range of factors like the hotel choice, length of stay and season will determine how much your vacation to Mayo costs.
What are the cheapest months to go to Mayo?
February, June and November are great times to search for cheap Mayo vacation packages. Traveling in less busy periods means you can typically find better prices on flights and hotels.
How many days is enough for Mayo?
With a well-organized travel plan, you can easily tick off the main Mayo attractions in a few days. But if you'd like to explore off the beaten track or go on day trips, consider booking your Mayo vacation for longer.
How to find the best Mayo package deals?
Use Expedia's handy filters to help you find some tempting Mayo package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your trip for midweek, or browse for Mayo package deals in the off-season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Mayo vacation as a package?
You can enjoy significant savings on your Mayo retreat by booking a personalized vacation package. Check the "Package" heading, then enter your destination and travel dates to see the best airfares and hotel prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Mayo?
If you've got your Mayo travel dates finalized, book as early as you can to bag some terrific deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spontaneous adventures? Our last-minute deals are perfect for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Mayo vacation packages?
Set off on your dream trip to Mayo with help from Expedia's Book Now, Pay Later vacations. No need to save like crazy or hold off until the next payday — we've teamed up with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans let you spread the total cost across 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to stick to your budget and snap up cheap deals while they last.
Explore a world of travel with Expedia
- Motels in Mayo
- Hotels near Lafayette Blue Springs State Park
- Pet-Friendly Hotels in Dowling Park
- Motels in O Brien
- Cabin Rentals in Mayo
- Gainesville Hotels
- Rv Parks in Mcalpin
- Rv Parks in O Brien
- Resorts in Dowling Park
- Condo Rentals in Lafayette County
- Cabin Rentals in O Brien
- 4 Star Hotels in Mayo
- Mayo Hotels
- Lake City Hotels
- Hotels near Ichetucknee Springs State Park
- Cabin Rentals in Day
- B&B in O Brien
- Best Western Hotels in O Brien
- Cabin Rentals in Branford
- Dowling Park Hotels
- Cottages in Dowling Park
- Hotels near Wes Skiles Peacock Springs State Park
- Hotels near Troy Spring State Park
- 4 Star Hotels in Dowling Park
- Apartments in Lafayette County
- Lafayette County Hotels
- Cabin Rentals in Mcalpin
- Perry Hotels
- O Brien Hotels
- Cottages in Lafayette County
- Cottages in Mcalpin
- Cabin Rentals in Dowling Park
- Day Hotels
- Cabin Rentals in Lafayette County
- Mcalpin Hotels
- 4 Star Hotels in O Brien
- Cottages in Mayo
- 5 Star Hotels in O Brien
- Rv Parks in Perry
- Rv Parks in Dowling Park
- Live Oak Hotels
- Branford Hotels
- Cottages in O Brien
- Suwannee River State Park
- Steinhatchee Vacations
- Ruth B. Kirby Gilchrist Blue Springs State Park
- Spirit of the Suwannee Music Park
- Florida Nature and Heritage Tourism Center
- Visit Dowling Park
- Sea Hag Marina
- Southside Sports Complex
- Madison Blue Springs State Park
- Fort White Vacations
- Blue Sink Canoe Launch
- Ichetucknee Springs State Park
- Wellborn Vacations
- First Federal Sportsplex
- Perry Train Depot
- Bob's River Place
- Branford Vacations
- Visit Branford
- Suwannee County Historical Museum
- Visit Mcalpin
- Visit O Brien
- Steinhatchee Public Boat Ramp
- Lake Frances Recreation Area
- Keaton Beach Vacations
- Visit Perry
- Taylor County Sports Complex
- Fort Steinhatchee Pier
- Visit Mayo
- Yogi Bear's Jellystone Park
- Ginnie Spring
- Epiphany Catholic Church
- Cross City Vacations
- Perry Vacations
- Bell Vacations
- Steinhatchee Falls
- Hagen Cove
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.