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Check prices for these dates, December 14 – 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Matlacha Isles-Matlacha Shores vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.
There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Matlacha Isles-Matlacha Shores vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.
Whenever you want to travel, a warm welcome awaits you in Matlacha Isles-Matlacha Shores. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Matlacha Isles-Matlacha Shores in high season.
Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $79 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!
At Expedia, we put the best Matlacha Isles-Matlacha Shores vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.
To find some top Matlacha Isles-Matlacha Shores rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Matlacha Isles-Matlacha Shores vacation.
If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Matlacha Isles-Matlacha Shores. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.
Yes, you can find vacation rentals close to top attractions in Matlacha Isles-Matlacha Shores, or you can choose a more remote option if you're looking for a relaxing stay.
OCT 17-24, NOV 7-14 and DEC 5-12 available Discounted Rates!! Beach 🏖️ 2min walk🩴: Visitors like this Matlacha Isles-Matlacha Shores vacation home rental. It is located near the beach and has an outdoor pool, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a selection of games and a hot tub.
Expedia has 3 vacation rentals for your stay in Matlacha Isles-Matlacha Shores.
While exploring the area, visit family-friendly sights like Sun Splash Water Park, or get outside and enjoy nature at Four Mile Cove Ecological Preserve. In the larger area, you’ll find Griffen American Center for Haitian Art and Key West Express.
Vacation rentals are privately owned properties you can reserve for a couple days or more in Matlacha Isles-Matlacha Shores. Vacation rentals offer extras such as WiFi and washers and dryers so you'll feel right at home. If you're concerned about cleanliness, a vacation rental can offer a sense of privacy away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.