Find hotels in Matlacha Isles-Matlacha Shores, FL from $75

Start date: Check-in selected.
To Date
End date: Check-out
  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Matlacha Isles-Matlacha Shores hotels

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
Cape Coral
9.6 out of 10, Exceptional, (213)
"Place was great. Nice and neat perfect for what i needed."
United States
Michael
$135 nightly
The price is $151
Jan 1 - Jan 2, 2026
Total with taxes and fees
Matlacha on Shoreview

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
Pelican
9.0 out of 10, Wonderful, (1004)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
$237 nightly
The price is $265
Jan 4 - Jan 5, 2026
Total with taxes and fees
The Westin Cape Coral Resort At Marina Village

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
8.8 out of 10, Excellent, (1001)
"Great Place to Stay!"
United States
JUDY
$131 nightly
The price is $146
Dec 25 - Dec 26
Total with taxes and fees
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
Fort Myers Beach
9.0 out of 10, Wonderful, (1032)
"Clean rooms lovely view of Beach and pool area."
United States
Laurice-Larry
$175 nightly
The price is $196
Jan 7 - Jan 8, 2026
Total with taxes and fees
Lani Kai Beachfront Resort

Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites
2.5 star property
Fort Myers
8.8 out of 10, Excellent, (1114)
"Clean room, old property and fresh, varied options for breakfast"
Canada
supriya
$87 nightly
The price is $97
Dec 25 - Dec 26
Total with taxes and fees
Best Western Fort Myers Inn & Suites

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
Fort Myers Beach
9.4 out of 10, Exceptional, (1202)
"Friendly staff, fun kid events "
United States
Payge
$258 nightly
The price is $288
Jan 11 - Jan 12, 2026
Total with taxes and fees
Pink Shell Beach Resort and Marina

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
Daniels Corridor
9.6 out of 10, Exceptional, (1004)
"Clean rooms and wonderful breakfast. Appreciated the airport shuttle as well."
United States
Susan
$135 nightly
The price is $151
Dec 27 - Dec 28
Total with taxes and fees
Holiday Inn Express & Suites Fort Myers Airport by IHG

Hampton Inn Fort Myers-Airport & I-75

Hampton Inn Fort Myers-Airport & I-75
3.5 star property
Daniels Corridor
9.0 out of 10, Wonderful, (1004)
"Clean room, nice staff and great breakfast!"
United States
Gina
$125 nightly
The price is $139
Dec 31 - Jan 1, 2026
Total with taxes and fees
Hampton Inn Fort Myers-Airport & I-75

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
Hancock
9.4 out of 10, Exceptional, (746)
"Always great to stay here. "
United States
David
$131 nightly
The price is $146
Dec 25 - Dec 26
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
Fort Myers Beach
9.0 out of 10, Wonderful, (1000)
"Excellent room excellent view and amenities. "
United States
Paul
$261 nightly
The price is $292
Jan 4 - Jan 5, 2026
Total with taxes and fees
DiamondHead Beach Resort

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
Punta Rassa
8.4 out of 10, Very Good, (1003)
"This was thr best place that we have ever stayed at. "
United States
Matthew
$261 nightly
The price is $291
Dec 25 - Dec 26
Total with taxes and fees
Marriott Sanibel Harbour Resort & Spa

Edison Beach House

Edison Beach House
3.5 star property
Fort Myers Beach
9.4 out of 10, Exceptional, (1588)
"Awesome stay "
United States
mary
$213 nightly
The price is $238
Jan 2 - Jan 3, 2026
Total with taxes and fees
Edison Beach House

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
Fort Myers Beach
9.0 out of 10, Wonderful, (1722)
"Great place "
United States
Debra Sue
$365 nightly
The price is $408
Dec 25 - Dec 26
Total with taxes and fees
Margaritaville Beach Resort Fort Myers

Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina
3.0 star property
Fort Myers Beach
9.2 out of 10, Wonderful, (1008)
"Rooms were very clean, and the staff was amazing."
United States
Deborah
$205 nightly
The price is $226
Dec 25 - Dec 26
Total with taxes and fees
Matanzas Inn Bayside Resort and Marina

Home2 Suites by Hilton Fort Myers Colonial Blvd

Home2 Suites by Hilton Fort Myers Colonial Blvd
3.0 star property
Fort Myers
9.4 out of 10, Exceptional, (579)
"The food was great "
United States
Adolph
$126 nightly
The price is $141
Jan 4 - Jan 5, 2026
Total with taxes and fees
Home2 Suites by Hilton Fort Myers Colonial Blvd

Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport
2.5 star property
Daniels Corridor
8.8 out of 10, Excellent, (1120)
"Great staff"
United States
Alison
$94 nightly
The price is $105
Dec 25 - Dec 26
Total with taxes and fees
Comfort Inn & Suites Fort Myers Airport

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
Caloosahatchee
9.4 out of 10, Exceptional, (1078)
"Is great place to stay."
United States
Anastassia
$129 nightly
The price is $144
Dec 25 - Dec 26
Total with taxes and fees
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Luminary Hotel & Co., Autograph Collection

Luminary Hotel & Co., Autograph Collection
4.0 star property
Fort Myers River District
9.2 out of 10, Wonderful, (482)
"Top floor bar was a great place to get away from things"
United States
Eugene
$237 nightly
The price is $264
Jan 4 - Jan 5, 2026
Total with taxes and fees
Luminary Hotel & Co., Autograph Collection

StudioRes Fort Myers Airport

StudioRes Fort Myers Airport
3.0 star property
Fort Myers
8.8 out of 10, Excellent, (16)
"Clean room, staff, amenities, easy check in, easy access to gas stations, restaurants, and retail. "
United States
Gina
$101 nightly
The price is $113
Dec 30 - Dec 31
Total with taxes and fees
StudioRes Fort Myers Airport

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
Villas
8.8 out of 10, Excellent, (1000)
"Great hotel and location and good value. "
United States
Amy
$126 nightly
The price is $141
Jan 1 - Jan 2, 2026
Total with taxes and fees
Doubletree by Hilton Fort Myers at Bell Tower Shops
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Matlacha Isles-Matlacha Shores attractions

Top Matlacha Isles-Matlacha Shores Hotel Reviews

More cheap stays in Matlacha Isles-Matlacha Shores

Hotels in Matlacha Isles-Matlacha Shores with star-rating

Frequently asked questions

What is the best area to stay in Matlacha Isles-Matlacha Shores?
The best area to stay in Matlacha Isles-Matlacha Shores is directly within Matlacha, particularly along Pine Island Road and the surrounding side streets.

This area is the vibrant heart of the community, known for its colorful buildings, art galleries, and waterfront restaurants. Pine Island Road is the main thoroughfare, easily accessible and lined with unique local businesses. The area's layout offers its connection to the water, with many accommodations offering canal access.

Couples looking for a peaceful and scenic getaway will find Matlacha ideal. The small, walkable nature of the area allows for relaxed strolls through art galleries, enjoying fresh seafood at waterside eateries, and watching the sunset over the water. Its tranquil setting is great for those who appreciate natural beauty and a slower pace.

For travelers who enjoy fishing and watersports, staying in Matlacha is particularly convenient. Many accommodations provide direct access to the canals, making it easy to launch kayaks, paddleboards, or small boats.
When is the best time to go to Matlacha Isles-Matlacha Shores?
The best time to go to Matlacha Isles-Matlacha Shores is during the dry season, from November to May, when the weather is consistently pleasant and ideal for outdoor activities.

During these months, you'll experience sunny days with comfortable temperatures, typically ranging from the low 70s to mid-80s Fahrenheit. This weather is great for enjoying the area's fishing, boating, and exploring the colorful art galleries and shops along Pine Island Road. It's also prime time for wildlife viewing, including various bird species and manatees.

Travelers looking for a quiet escape will find this period particularly appealing. The cooler temperatures and lower humidity make walking or cycling around the islands more enjoyable.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Matlacha Isles-Matlacha Shores.
How can I save on a Matlacha Isles-Matlacha Shores hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Matlacha Isles-Matlacha Shores hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Matlacha Isles-Matlacha Shores hotel?
Prices for hotels in Matlacha Isles-Matlacha Shores often vary, but you can find a great deal from $75 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia