Mesagne Vacations from $1,053

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Your Mesagne Vacation

When a getaway to the city is calling, answer it with a vacation package to Mesagne. The neighborhood of Francavilla Fontana Historic Centre, which is good for views, history and walking, makes a great base for your adventures. Mesagne Castle, Sanctuary of S.S. Maria di Cotrino and Ribezzi Petrosillo House Museum are just a few of the many attractions worth visiting during your trip to Mesagne. Whoever you're escaping with and whether your budget is big or small, your ultimate Mesagne vacation is just a few clicks away with Expedia.

The Latest Mesagne vacation packages

Price found within the past 48 hours. Click for updated prices.
Grande Albergo Internazionale

Grande Albergo Internazionale

4 out of 5
Brindisi Historic Center
per person
Nov 9 - Nov 15
found 1 day ago
Roundtrip flight included
Indianapolis (IND) to Brindisi (BDS)
8.2/10 Very Good! (403 reviews)
We had an awesome stay on this hotel. The staff are friendly especially

Reviewed on Jul 22, 2025

Baglioni Masseria Muzza Resort & Spa

Baglioni Masseria Muzza Resort & Spa

5 out of 5
Save 100% on your flight
per person
Sep 21 - Sep 27
found 1 day ago
Roundtrip flight included
Indianapolis (IND) to Brindisi (BDS)
9.4/10 Exceptional! (20 reviews)
The staff were so welcoming and very friendly. They were always on hand to help us plan our itinerary - superb service!

Reviewed on Jul 22, 2025

Casale del Murgese

Casale del Murgese

4 out of 5
per person
Nov 9 - Nov 15
found 1 day ago
Roundtrip flight included
Indianapolis (IND) to Brindisi (BDS)
9/10 Wonderful! (11 reviews)
It was a lovely location. I would advise hiring a car for transport

Reviewed on Jul 21, 2025

Hotel Jonico

Hotel Jonico

4 out of 5
Save 100% on your flight
per person
Nov 9 - Nov 15
found 1 day ago
Roundtrip flight included
Indianapolis (IND) to Brindisi (BDS)
8.2/10 Very Good! (28 reviews)
Palazzo Ducale Venturi - Luxury Relais & Wellness

Palazzo Ducale Venturi - Luxury Relais & Wellness

5 out of 5
per person
Nov 9 - Nov 15
found 1 day ago
Roundtrip flight included
Indianapolis (IND) to Brindisi (BDS)
9.2/10 Wonderful! (22 reviews)
All the staff are so helpful and friendly. Breakfast was great! So many lovely patisserie items and then I had smoked salmon and poached eggs every day… my favourite! Pool was sparkling clean and always plenty of sun loungers. Location quite remote but we found a few good restaurants nearby and a friendly little local bar with a talking parrot!

Reviewed on Aug 9, 2022

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Discover the most popular places to visit in Mesagne

Mesagne Castle

You can browse the exhibits at Mesagne Castle, a museum with a story of its own, during your travels to Mesagne. While you're in the area, stroll along the waterfront.

Mesagne Castle

What to do in Mesagne

Brindisi: Guided Tour to the Roman Port

BRINDISI private tour: the most important Roman Empire port

$346
per traveler
BRINDISI private tour: the most important Roman Empire port
Brindisi: Alberobello, Locorotondo & Ostuni Tour with Brunch

Brindisi: Alberobello, Locorotondo & Ostuni Tour with Brunch

$93
per adult
Brindisi: Alberobello, Locorotondo & Ostuni Tour with Brunch
Polignano a Mare

From Brindisi. Ostuni, Alberobello and Polignano a Mare Tour

$155
per adult
From Brindisi. Ostuni, Alberobello and Polignano a Mare Tour
See all activities in Mesagne

Mesagne Hotel Deals

Masseria Malvindi

Masseria Malvindi

5 out of 5
Strada Provinciale 74, Mesagne, BR
Fully refundableReserve now, pay when you stay
$194 nightly
The price is $213 total per night from Sep 1 to Sep 2
$213 total
Sep 1 - Sep 2
Total includes taxes and fees
9.6/10 Exceptional! (26 reviews)
The perfect relaxing getaway
"Wonderful. For us; perfect. Beautifully appointed in a minimalist style. All rooms open onto the pool but in such a way that there is complete privacy…rooms are set back underneath a gorgeous canopy of vines in an L shaped colonnade. There were never more than half a dozen people at the pool, which ..."

Reviewed on Aug 9, 2025

Masseria Malvindi
Tenuta Moreno

Tenuta Moreno

4 out of 5
Contrada Moreno, S.S. 7 uscita Latiano Est, Mesagne, BR
$163 nightly
The price is $179 total per night from Aug 29 to Aug 30
$179 total
Aug 29 - Aug 30
Total includes taxes and fees
8.6/10 Excellent! (49 reviews)
"Great property- rooms a bit too small Could barely have luggage in the room"

Reviewed on Sep 18, 2024

Tenuta Moreno
Antica Masseria Martuccio

Antica Masseria Martuccio

4 out of 5
Sala Ricevimenti C Da Martuccio, Mesagne, BR
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $133 total per night from Aug 23 to Aug 24
$133 total
Aug 23 - Aug 24
Total includes taxes and fees
9.4/10 Exceptional! (76 reviews)
"We enjoyed our vacation in this lovely accommodation. This place is perfect for relaxing getaway. Staff Is incredibly friendly!"

Reviewed on Aug 17, 2025

Antica Masseria Martuccio
See all 7,535 properties in Mesagne
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Mesagne vacation package cost?
Offering excellent value package deals from $1,053 on Expedia, you'll be surprised at how little a vacation to Mesagne costs! Our packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Mesagne?
You can generally find reduced prices and better availability in November, December and January. Check out our cheap Mesagne vacation packages and you could score some great off-season discounts.
How many days is enough for Mesagne?
With a well-organized schedule, you can easily tick off the top Mesagne attractions in a handful of days. But if you prefer to explore off the beaten track or take day trips, think about booking your Mesagne vacation for longer.
How to find the best Mesagne package deals?
Start your search for a Mesagne package deal by entering your destination and travel dates under our "Packages" tab. Then select some filters, like "Property type" and "Amenities," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the perfect Mesagne package deal right away, simply switch up your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Mesagne escape off to a flying start.
Is it cheaper to book a Mesagne vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking flights and stays individually. Better still, you can customize your Mesagne getaway to match your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Mesagne?
If you've got your Mesagne travel dates finalized, book as soon as you can to bag some outstanding deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are great for impromptu escapes.
How to plan a trip to Mesagne?

  1. Pick the right time to travel: Your schedule, preferred season and the type of weather you like can all influence your decision on when to travel to Mesagne.
  2. Set a budget: Consider costs such as food, flights and transportation when working out how much to put aside for your trip to Mesagne. Then, choose a property that fits your budget, whether that's an affordable option or a high-end getaway.
  3. Organize your Mesagne getaway with Expedia's trip planning tool: Search for and book hotels and activities all in one place. You can also collaborate with friends and family to plan an unforgettable trip to Mesagne together.
  4. Work out your trip length: Think about how long you want to spend discovering Mesagne. Plan your days so you can get to all the activities and attractions you're interested in without rushing.
  5. Bundle your bookings: With your travel dates in place, you can combine your flights, hotels, car rental and more into a customized Mesagne vacation package.
  6. Add on excursions and experiences: Take a look at our travel guide to find some exciting things to do in Mesagne. Book tickets or make reservations in advance to save time and avoid the hassle of trying to find activities when you arrive.

Does Expedia offer Book Now, Pay Later Mesagne vacation packages?
Jet off on your perfect trip to Mesagne with our Book Now, Pay Later vacations. No need to save like crazy or wait until your next paycheck — we've partnered with online lender Affirm to offer you flexibility with your finances. Our vacation packages with payment plans allow you to spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's a breeze to stay on budget and snap up cheap deals before they disappear.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.