Mill Creek Vacation Rentals from $124: Search Short-Term Rentals

Q: What's the top vacation rental that Mill Creek has to offer?

* On the Wine Trail * Hot Tub * Wi-Fi * : This vacation home rental near Mill Creek is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

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Our top choices for Mill Creek vacation rentals

A wooden cabinet with a microwave, coffee maker, and plates.

1. Cozy and Updated Farmhouse with King Suite

Anna

Kathy H.

$149 nightly

Oct 13 - Oct 14

Total with taxes and fees

A serene outdoor area with a pond, surrounded by trees and a grassy lawn. There are two wooden benches facing the water.

2. Charming cottage overlooking Lake Acre

Dongola

Paul D.

$239 nightly

Oct 11 - Oct 12

Total with taxes and fees

A log cabin with a metal roof, two windows, a door, and a porch with two rocking chairs and a small table.

3. Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Anna

Brandon

$189 nightly

Oct 13 - Oct 14

Total with taxes and fees

A brick building with a sign reading "1898 Guesthouse".

4. Stunning 2 bedroom in town, close to Shawnee National Forest

Jonesboro

Dylan

$270 nightly

Oct 21 - Oct 22

Total with taxes and fees

A living room with a TV, a fireplace, a sofa, and wall art.

5. Little Blue Cottage on Spanish

Cape Girardeau

Jeremy W.

$101 nightly

Oct 11 - Oct 12

Total with taxes and fees

A cozy room with a wooden table and chairs, a large window, and a door with a sign.

6. Cozy cabins on beautiful Horseshoe Lake

Olive Branch

JASEN

$133 nightly

Oct 11 - Oct 12

Total with taxes and fees

A small, single-story building with a wooden exterior and large windows.

7. The Rested Duck Mallard Room

Olive Branch

mike b.

$133 nightly

Oct 11 - Oct 12

Total with taxes and fees

A room with a pool table, a sofa, and a dining table with chairs.

8. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Villa Ridge

Brian F.

$252 nightly

Oct 11 - Oct 12

Total with taxes and fees

A wooden cabin with a porch, a door with a wreath, and potted plants.

9. Contemporary Glamping with Native American Appeal

Anna

Jonathan P.

$312 nightly

Oct 13 - Oct 14

Total with taxes and fees

A spacious living area with a kitchen, a dining table, and comfortable seating.

10. Peach Tree Inn, downtown Cobden

Cobden

Wade T.

$210 nightly

Oct 12 - Oct 13

Total with taxes and fees

A spacious living room with a brown leather sofa, a dining area with a wooden table and chairs, a kitchen with white cabinets and a central island, and large windows with blinds.

11. Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.

Anna

Molly J.

$259 nightly

Oct 12 - Oct 13

Total with taxes and fees

A loft-style room with a wooden interior, a sofa, a table with a pumpkin decoration, and a staircase leading to an upper level.

12. Peaceful secluded cabin located near Horseshoe Lake

Miller City

George B.

$206 nightly

Oct 12 - Oct 13

Total with taxes and fees

A large, two-story house with a wrap-around porch, surrounded by a well-maintained garden with various flowering plants.

13. Magical Victorian near hiking / wine trail

Anna

Rachel H.

$353 nightly

Oct 19 - Oct 20

Total with taxes and fees

A cozy cabin interior with a wooden interior, a dining area with a table and chairs, a kitchen with a refrigerator and microwave, and a window with a view of greenery.

14. Shawnee Wine Trail Farm Stay

Makanda

Abigail J.

$117 nightly

Oct 19 - Oct 20

Total with taxes and fees

A two-story house with a front porch, a small garden, and a white picket fence.

15. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Cape Girardeau

Pynktoria !.

$300 nightly

Oct 12 - Oct 13

Total with taxes and fees

16. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Cape Girardeau

Sara C.

$216 nightly

Oct 11 - Oct 12

Total with taxes and fees

17. Purple Tiny House with Fire pit & Nature

Cape Girardeau

Shawn A.

$193 nightly

Oct 11 - Oct 12

Total with taxes and fees

18. The Little Cape Lofted Cottage | Creek & Nature

Cape Girardeau

"It was very clean and had a good feel. It was well stocked. I appreciated the cute little ice tray in the freezer that was full. I also appreciated 4 waters in the fridge. The bed on the loft upstairs was atrocious. You can feel the springs through the mattress. The downstairs bed was good. The pillows were fantastic! I’m a pillow snob. We needed a quick place to land for a church function so I can’t say much about the outside amenities as we weren’t there much. But it was a beautifully tucked...

Trisha S.

$218 nightly

Oct 11 - Oct 12

Total with taxes and fees

A bedroom with a bed, a bottle of J. Roget champagne, two glasses, and a plate with snacks.

19. The Cottage, Rusted Route Farms

Jackson

Renee C.

$199 nightly

Oct 11 - Oct 12

Total with taxes and fees

A wooden deck with two white Adirondack chairs and a small round table.

20. Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass

Alto Pass

brian O.

$234 nightly

Oct 20 - Oct 21

Total with taxes and fees

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Top Mill Creek Hotel Reviews

* On the Wine Trail * Hot Tub * Wi-Fi *

10/10 Excellent

"Had a great time!!! It was nice to relax in the hot tub each night after full days on the wine trail. Great host!!!"

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

10/10 Excellent

"The property is beautiful as well as the house. The property has enough trees for shade, it's i.e, not so heavily wooded that it's isolating. The owners and another family are close by and really helpful when we texted with a question. The hot tub is completely private and lit in the evening with soft lighting :). The grill is in the same area. The fire pit is on the other side by the dock. We woke early our last day to sit on the dock and watch the sunrise. The house … is oh so uniquely charming with a front and a side deck!!!!!! Each room is tastefully decorated and curated for a happy, fun, and welcome experience. Everything is stocked, easy to find, with house directions and suggestions for outings printed in a welcome binder, The town of Anna is 5 minutes away where we went to the Farmstead for hot/cold sandwiches with lots of delicious homemade amish selections/option for takeaway. We went to the newly opened HubBarn, a repurposed grocery store, that had 60 booths of new and thrift items - a real treasure. We will certainly be coming back to hike the beautiful sacred land of the Shawnee National Forest."

Secluded, Log Rental Cabin, Private Hot Tub,on Southern Illinois Wine Trail

10/10 Excellent

"Quiet, peaceful, and endless cows next door. We loved the place. One note: the hottub was foaming a lot. I’m thinking this might have been a chemical reaction. By Thursday morning it had dissipated. Very convenient to the hiking trails."

Find out more about Mill Creek

Everything you need to know about Mill Creek vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mill Creek vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mill Creek vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mill Creek vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mill Creek. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mill Creek in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $124 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Mill Creek rentals

At Expedia, we put the best Mill Creek vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mill Creek rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mill Creek vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mill Creek. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Mill Creek?

Yes, there are vacation rentals near the most popular local attractions in Mill Creek, or you can select a more remote option if you want a relaxing place to stay.

What's the top vacation rental that Mill Creek has to offer?

* On the Wine Trail * Hot Tub * Wi-Fi *: This vacation home rental near Mill Creek is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What can I see and do in Mill Creek?

While exploring the area, visit family-friendly sights like Henry N Barkhausen Cache River Wetlands Center, or get outside and enjoy nature at Lower Cache River Access Area. In the larger area, you’ll find Trail of Tears State Park and Century Casino & Hotel Cape Girardeau.

What are vacation rentals like in Mill Creek?

Vacation rentals are private accommodations you can stay in for a few days or a quick weekend in Mill Creek. Vacation rentals offer amenities such as kitchens and laundry facilities so you'll have everything you need. If you're concerned about cleanliness, a vacation rental can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for small groups.

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Check prices for these dates

Our top choices for Mill Creek vacation rentals

1. Cozy and Updated Farmhouse with King Suite

2. Charming cottage overlooking Lake Acre

3. Rest, Relax and Renew. Our log cabin experience awaits your arrival.

4. Stunning 2 bedroom in town, close to Shawnee National Forest

5. Little Blue Cottage on Spanish

6. Cozy cabins on beautiful Horseshoe Lake

7. The Rested Duck Mallard Room

8. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

9. Contemporary Glamping with Native American Appeal

10. Peach Tree Inn, downtown Cobden

11. Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.

12. Peaceful secluded cabin located near Horseshoe Lake

13. Magical Victorian near hiking / wine trail

14. Shawnee Wine Trail Farm Stay

15. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

16. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

17. Purple Tiny House with Fire pit & Nature

18. The Little Cape Lofted Cottage | Creek & Nature

19. The Cottage, Rusted Route Farms

20. Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass

Find vacation rentals that suit your style

Top Mill Creek Hotel Reviews

* On the Wine Trail * Hot Tub * Wi-Fi *

Pear Tree Inn Cape Girardeau West

Quality Inn Cape Girardeau North

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Hampton Inn Cape Girardeau I 55 East

Courtyard by Marriott Cape Girardeau Downtown

Secluded, Log Rental Cabin, Private Hot Tub,on Southern Illinois Wine Trail

Find out more about Mill Creek

Frequently asked questions

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