Mill Creek Vacation Rentals

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Our top choices for Mill Creek vacation rentals

9.8 out of 10, Exceptional, (10)
"We loved our stay and all the wonderful animals we got to see."
United States
Jasmine B.
$114 nightly
The price is $120
Dec 16 - Dec 17
Total with taxes and fees
Shawnee Wine Trail Farm Stay
10.0 out of 10, Exceptional, (101)
"Location was great, everything was great for what we were there for. Already booked again for November. "
United States
carlton h.
$265 nightly
The price is $281
Dec 21 - Dec 22
Total with taxes and fees
Charming cottage overlooking Lake Acre
10.0 out of 10, Exceptional, (403)
"Very clean, courteus staff. Beautiful area and quiet. Very relaxing."
United States
Tommy
$191 nightly
The price is $202
Dec 18 - Dec 19
Total with taxes and fees
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
10.0 out of 10, Exceptional, (6)
"Staying at this location was wonderful. I loved the open space & the cabin was very welcoming as well as clean & tidy. It was perfect for what I was going for! Thank you"
United States
Christina S.
$114 nightly
The price is $120
Dec 16 - Dec 17
Total with taxes and fees
Après Vine Tiny Cabin at Panther's Rest Farm
9.6 out of 10, Exceptional, (23)
"Very nice and peaceful place to stay. Great hiking trails to explore. Host Keith, was very nice guy and very responsive if you need anything. I would highly recommend any of his cabins. "
United States
Belinda
$128 nightly
The price is $136
Dec 17 - Dec 18
Total with taxes and fees
Maple Ridge Cabin at Panther's Rest
9.8 out of 10, Exceptional, (155)
"Our 2nd time staying here and it was perfect"
United States
machelle p.
$282 nightly
The price is $284
Dec 17 - Dec 18
Total with taxes and fees
Contemporary Glamping with Native American Appeal
10.0 out of 10, Exceptional, (16)
"Had a great stay. The treehouse was unique and a great get away spot while enjoying the local winery’s. We’ll be back for more fun this upcoming fall. "
United States
Nathaniel M.
$187 nightly
The price is $198
Dec 16 - Dec 17
Total with taxes and fees
Secluded treehouse with indoor fireplace
9.8 out of 10, Exceptional, (35)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
$133 nightly
The price is $140
Dec 22 - Dec 23
Total with taxes and fees
Cozy cabins on beautiful Horseshoe Lake
9.4 out of 10, Exceptional, (45)
"This place is AWESOME! It's clean, artsy, fun, and if we ever have a chance, we will certainly return!"
United States
Jordan S.
$132 nightly
The price is $138
Dec 16 - Dec 17
Total with taxes and fees
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
10.0 out of 10, Exceptional, (19)
"Went for a peaceful weekend and got just that! Very beautiful location and very clean and neat cabin! Close to the wineries. Will definitely be going back! "
United States
Laci H.
$218 nightly
The price is $240
Jan 13 - Jan 14, 2026
Total with taxes and fees
Cozy 2BR A-Frame Cabin w/ Hot Tub & Lake Views
10.0 out of 10, Exceptional, (3)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
$310 nightly
The price is $310
Dec 16 - Dec 17
Total with taxes and fees
Gorgeous 1856 Log Cabin, Completely Renovated
10.0 out of 10, Exceptional, (4)
"great place. wonderful host."
United States
Carla m.
$237 nightly
The price is $252
Dec 16 - Dec 17
Total with taxes and fees
Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Cabin in Olive Branch

The Rested Duck Mallard Room
9.2 out of 10, Wonderful, (25)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
$133 nightly
The price is $140
Dec 21 - Dec 22
Total with taxes and fees
The Rested Duck Mallard Room
8.6 out of 10, Excellent, (36)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
United States
Emily D.
$206 nightly
The price is $214
Dec 16 - Dec 17
Total with taxes and fees
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
10.0 out of 10, Exceptional, (148)
"Such a great place and location"
United States
Tracy H.
$229 nightly
The price is $245
Dec 16 - Dec 17
Total with taxes and fees
Serenity South -- Gardens, River-Views, and Refreshing Space

Mobile Home in Jackson

The Cottage, Rusted Route Farms
10.0 out of 10, Exceptional, (2)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
$195 nightly
The price is $195
Dec 22 - Dec 23
Total with taxes and fees
The Cottage, Rusted Route Farms
2.0 star property
$139 nightly
The price is $148
Dec 16 - Dec 17
Total with taxes and fees
Cozy and Updated Farmhouse with King Suite
10.0 out of 10, Exceptional, (102)
"We loved our stay! The accommodations were clean and comfortable. The cabin atmosphere very was relaxing. We will be back. "
United States
Beth C.
Contemporary Glamping with Native American Appeal!

Vacation Home in Cape Girardeau

Little Blue Cottage on Spanish
8.6 out of 10, Excellent, (48)
"I would definitely stay here again!"
United States
Bonita
$101 nightly
The price is $101
Dec 16 - Dec 17
Total with taxes and fees
Little Blue Cottage on Spanish
9.8 out of 10, Exceptional, (8)
"Awesome"
United States
Luke K.
$186 nightly
The price is $205
Jan 5 - Jan 6, 2026
Total with taxes and fees
Historic Farm Cottage on 800-Acre Orchard
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mill Creek Hotel Reviews

Find out more about Mill Creek

Everything you need to know about Mill Creek vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mill Creek vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mill Creek vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mill Creek vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mill Creek. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mill Creek in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $101 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Mill Creek rentals

At Expedia, we put the best Mill Creek vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mill Creek rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mill Creek vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mill Creek. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Mill Creek?

Yes, there are vacation rentals near the most popular local attractions in Mill Creek, or you can select a more remote option if you want a relaxing place to stay.

What's the top vacation rental that Mill Creek has to offer?

Secluded treehouse with indoor fireplace: This vacation home rental near Mill Creek offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Make the most of the selection of games in this rental home to help you unwind.

What can I see and do in Mill Creek?

While exploring the area, visit family-friendly sights like Henry N Barkhausen Cache River Wetlands Center, or get outside and enjoy nature at Dongola Lake. In the larger area, you’ll find Trail of Tears State Park and Isle Casino Cape Girardeau.

What are vacation rentals like in Mill Creek?

Vacation rentals are private accommodations you can stay in for a few days or a quick weekend in Mill Creek. Vacation rentals offer amenities such as kitchens and laundry facilities so you'll have everything you need. If you're concerned about cleanliness, a vacation rental can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for small groups.