Mill Creek Vacations from $500

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

The Latest Mill Creek vacation packages

Price found within the past 48 hours. Click for updated prices.
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

3 out of 5
Price was $565, price is now $500 per person
$500
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip flight included
Boston (BOS) to Cape Girardeau (CGI)
9.6/10 Exceptional! (77 reviews)
This hotel has a lot of character and was so cozy. The owners have done a wonderful job creating a lovely, super easy hotel experience. The diner and mercantile were very cool. Everything felt very clean and welcoming.

Reviewed on Aug 18, 2025

Hampton Inn Carbondale

Hampton Inn Carbondale

2.5 out of 5
Price was $828, price is now $657 per person
$657
per person
Nov 20 - Nov 24
found 5 hours ago
Roundtrip non-stop flight included
Memphis (MEM) to Cape Girardeau (CGI)
8.4/10 Very Good! (580 reviews)
The evening we stayed here was move in weekend for SIU and we had moved our son into his apartment. We chose this location for its price and amenities. It was very unfortunate that management chose to shut down the pool and hot tub for routine maintenance this weekend and we could not enjoy the pool or the spa on the hottest day of the year. Seems a little suspect or just bad timing. I don’t believe I will stay here on any future visits.

Reviewed on Aug 16, 2025

Makanda Inn

Makanda Inn

3.5 out of 5
Price was $915, price is now $793 per person
$793
per person
Nov 20 - Nov 24
found 5 hours ago
Roundtrip non-stop flight included
Memphis (MEM) to Cape Girardeau (CGI)
10/10 Exceptional! (33 reviews)
Peaceful and relaxing.

Reviewed on May 20, 2025

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 out of 5
Price was $926, price is now $804 per person
$804
per person
Nov 20 - Nov 24
found 5 hours ago
Roundtrip non-stop flight included
Memphis (MEM) to Marion (MWA)
9.4/10 Exceptional! (364 reviews)
Very nice room, nice scenery not an interstate running thru it

Reviewed on Sep 1, 2025

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
Price was $876, price is now $768 per person
$768
per person
Nov 20 - Nov 24
found 5 hours ago
Roundtrip non-stop flight included
Memphis (MEM) to Marion (MWA)
9.4/10 Exceptional! (467 reviews)
Very clean, nice breakfast spread.

Reviewed on Aug 30, 2025

Don't see what you're looking for?
See all available trips from Columbus to Mill Creek
View all trips

Mill Creek Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Sep 7 to Sep 8
$102 total
Sep 7 - Sep 8
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $132 total per night from Sep 3 to Sep 4
$132 total
Sep 3 - Sep 4
Total with taxes and fees
The Riverview
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Sep 3 to Sep 4
$79 total
Sep 3 - Sep 4
Total with taxes and fees
Pear Tree Inn Cape Girardeau Near the Medical Center
See all 151 properties in Mill Creek
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Mill Creek vacation package cost?
You'll find cheap prices from $500 on Expedia for your Mill Creek escape. However, a range of factors like the hotel choice, length of stay and season will influence how much your vacation to Mill Creek costs.
What are the cheapest months to go to Mill Creek?
If you'd like to snag a cheap Mill Creek vacation package, consider planning a trip in January, April and May. You're likely to find lower prices on airfares and hotels during these quieter months — perfect for a budget-friendly getaway.
How many days is enough for Mill Creek?
The ideal length for your Mill Creek vacation depends on what you'd like to do and see. Usually, a few days to a week will give you time to check out all the leading sights and discover some hidden spots along the way.
How to find the best Mill Creek package deals?
Use Expedia's filters to find some fabulous Mill Creek package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your escape for midweek, or look for Mill Creek package deals in the off-season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Mill Creek vacation as a package?
You can enjoy significant savings on your Mill Creek break by booking a personalized vacation package. Click on the "Package" heading, then select your destination and travel dates to browse the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Mill Creek?
If you have your Mill Creek travel dates finalized, book as soon as you can to grab some outstanding deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spontaneous adventures? Our last-minute deals are ideal for impromptu escapes.
Does Expedia offer Book Now, Pay Later Mill Creek vacation packages?
If you're like us, you love going away but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the cost of your Mill Creek vacation over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.