Pamplico Vacation Rentals

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Vacation Rentals in Pamplico

Secret SC Cabin on 100 acres Hot Tub Large Pond

Marion
9.6 out of 10, Exceptional, (173)
"We enjoyed how peaceful the place was. Loved getting to walk the trails. "
United States
Crystal R.
$432 nightly
The price is $470
Nov 17 - Nov 18
Total with taxes and fees
Secret SC Cabin on 100 acres Hot Tub Large Pond

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Florence
10.0 out of 10, Exceptional, (33)
"Very clean and comfortable.A perfect overnight stop on the way home from Florida."
United States
Julie R.
$253 nightly
The price is $284
Nov 17 - Nov 18
Total with taxes and fees
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Walking distance from one of South Carolina's top Medical centers.

Florence
9.8 out of 10, Exceptional, (42)
"The house was beautiful. We would stay there again!!"
United States
Stephanie L.
$209 nightly
The price is $234
Nov 25 - Nov 26
Total with taxes and fees
Walking distance from one of South Carolina's top Medical centers.

Peaceful Farm Getaway

Mullins
10.0 out of 10, Exceptional, (30)
"Nice quiet place to stay for a few weeks while I commuted locally for work. Definitely recommend! "
United States
Adam B.
$193 nightly
The price is $210
Nov 17 - Nov 18
Total with taxes and fees
Peaceful Farm Getaway

3-bedroom mobile home in peaceful Florence with AC, WiFi

Florence
3-bedroom mobile home in peaceful Florence with AC, WiFi

Great Home in the Greater Florence Area

Timmonsville
9.6 out of 10, Exceptional, (8)
"Nice location and home. Owner was very responsive and accommodating. Matt promptly addressed our initial concerns after checkin. I would consider this home again for potential future bookings. "
United States
LOUIS M.
Great Home in the Greater Florence Area

Hickory Haven 3Br Elegant Downtown Hidden Gem

Florence
9.6 out of 10, Exceptional, (19)
"Host was wonderful to deal with, easy to access, comfy beds, linens and beautifully decorated!"
United States
Paige D.
Hickory Haven 3Br Elegant Downtown Hidden Gem

Perfect Get-Away In The Heart Of Downtown Florence

2.0 star property
Florence
Perfect Get-Away In The Heart Of Downtown Florence

3-bedroom mobile home in Florence, SC

Florence
6.0 out of 10, (2)
"We were there for a friends wedding. We had a great time. Friday night family game (board game) night. Great place to stay to spend family time together. "
United States
Kary S.
3-bedroom mobile home in Florence, SC

Charming Cottage with easy access to local attractions-pet and kid friendly

Sellers
9.2 out of 10, Wonderful, (15)
"This location made it easy for us to travel to a local rehearsal dinner and wedding at Parker Pines. It was very rural, yet be aware of the adjacent railway that stays very active during the day and night. Overall we would recommend this little cottage that had everything we needed."
United States
Arna D.
$180 nightly
The price is $196
Nov 17 - Nov 18
Total with taxes and fees
Charming Cottage with easy access to local attractions-pet and kid friendly

Pineapple House: Historic. Southern Charm. Walk Downtown.

Florence
9.6 out of 10, Exceptional, (19)
"Love the house and location. Everyone in the process is a joy to work with. We will be back for certain."
United States
Andy H.
Pineapple House: Historic. Southern Charm. Walk Downtown.

Jacqueline Estates

Florence
10.0 out of 10, Exceptional, (10)
"neighbors but private! great communication with host and she provided snacks, coffe table, tea table, bar, and stocked kitchen!! loved that because i love to cook!"
United States
Serenity C.
Jacqueline Estates

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Marion
9.0 out of 10, Wonderful, (6)
"It was a great place. "
United States
Cindy N.
$549 nightly
The price is $598
Nov 17 - Nov 18
Total with taxes and fees
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Waterfront Paradise with Golf Course Views

Florence
6.4 out of 10, (16)
"The home is in desperate need of a few cosmetic repairs inside and out. The property is beautiful and the area is gorgeous for nice walks. There are many exterior doors in each of the bedrooms and it appears the doors do not lock from the inside but they are locked on the outside, these definitely need to be repaired. There are many rooms where wires are just hanging out of the wall and floor, they do not appear to be live, but it looks awful and makes you feel very uncomfortable. Many of the...
United States
Kimberly E.
Waterfront Paradise with Golf Course Views

Charming and Cozy 4BR 2BA House with Parking, Minutes from I-95 and Buc-ees

Florence
9.8 out of 10, Exceptional, (6)
"Everything about this location was great and the host was very kind. Thank you for making our stay comfortable. "
United States
Shatia G.
Charming and Cozy 4BR 2BA House with Parking, Minutes from I-95 and Buc-ees

Relaxing 3-Bedroom Getaway in Peaceful Cades – Sleeps 8

Cades
Relaxing 3-Bedroom Getaway in Peaceful Cades – Sleeps 8

Tasteful and peaceful unit near downtown

Florence
9.4 out of 10, Exceptional, (3)
"Everyone was nice ! Property was clean, safe and secure. Great location"
United States
Paul D.
Tasteful and peaceful unit near downtown

Family Retreat for vacations, weddings, family reunions and corporate retreats.

Florence
10.0 out of 10, Exceptional, (1)
"Great location and property."
United States
Jerry W.
Family Retreat for vacations, weddings, family reunions and corporate retreats.

3-story Home w/ Private Backyard in Florence!

3.0 star property
Florence
3-story Home w/ Private Backyard in Florence!

Cozy Mullins Retreat w/ Backyard & Covered Porch!

3.0 star property
Mullins
2.0 out of 10, (1)
"The house itself and near by houses on the same street are older but decently kept up, but please do your own research on this area prior to selecting this property. I was in a bit of a hurry on securing a place and this property allowed pets “with an added charge” not listed on the Expedia listing. Not being familiar with any areas surrounding Florence I wish I would have taken the time to properly research. "
United States
Jacob
Cozy Mullins Retreat w/ Backyard & Covered Porch!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pamplico Hotel Reviews

Find out more about Pamplico

Everything you need to know about Pamplico vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Pamplico vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Pamplico vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Pamplico vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Pamplico. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Pamplico in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $196 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Pamplico rentals

At Expedia, we put the best Pamplico vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Pamplico rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Pamplico vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Pamplico. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Pamplico?

Yes, we give you a choice of vacation rentals near top sights in Pamplico, or you can go with a secluded option if you're looking for relaxation.

What are some of the best vacation rentals in Pamplico?

Walking distance from one of South Carolina's top Medical centers.: This vacation home rental near Pamplico offers a garden, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What’s there to see and do in Pamplico?

While you're exploring the area, Lions Park and Florence Veterans Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Eastern Carolina Agricultural Fairgrounds and Francis Marion University.

What’s a vacation rental in Pamplico like?

Vacation rentals are private properties you can stay in for several days or longer in Pamplico. Vacation rentals offer amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of privacy away from public hotel elevators and lobbies packed with people while still allowing you a great travel experience. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive choice for a family getaway.