Title: Policlinico Vacation Packages 2026 from $1,118 | Expedia.com

[Hotels in Policlinico](https://expedia.com/Policlinico-Rome-Hotels.0-n6145020-0.Travel-Guide-Filter-Hotels)[Flights to Rome](https://expedia.com/Cheap-Flights-To-Rome.d179899.Travel-Guide-Flights)[Things to do in Rome](https://expedia.com/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)[Car Rentals in Policlinico](https://expedia.com/Car-Rentals-In-Policlinico.d6145020.Car-Rental-Guide)

![](https://images.trvl-media.com/place/6145020/5b0912aa-e38f-4e9c-a21a-720ccb135b13.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Policlinico Vacations from $1,118

## Book a Hotel + Flight or Car together to unlock savings

- ##  
Plan, book, travel with confidence
- ###  
Better together  
Save up to $1,045 when you book a flight and hotel together\*
- ###  
Find the right fit  
With over 300,000 hotels worldwide, it's easy to create a perfect package
- ###  
Rest easy  
Plan, book, and manage your trip all in one place

## Your Policlinico Vacation

Take the hassle out of organizing your next escape by booking a Policlinico vacation package. Take in the sights and sounds of this enticing neighborhood and experience what it has to offer. Kick off your trip to Policlinico with a visit to nearby attractions such as [Roman Forum](https://www.expedia.com/Roman-Forum-Rome-City-Centre.d502481.Vacation-Attraction), [Pantheon](https://www.expedia.com/Pantheon-Rome-City-Centre.d502483.Vacation-Attraction) and [Piazza Navona](https://www.expedia.com/Piazza-Navona-Rome-City-Centre.d508631.Vacation-Attraction). Expedia can put your travel plans into action. Book your dream Policlinico vacation today.

## The Latest Policlinico Vacation Packages

Price found within the past 48 hours. Click for updated prices.

![Relais de la Poste](https://images.trvl-media.com/lodging/39000000/38910000/38902300/38902220/c47eaf80_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Relais de la Poste

Rome City Centre

$1,118

per person

Apr 21 - Apr 24

found 1 day ago

Roundtrip flight included

New York (NYC) to Rome (FCO)

9.2/10 Wonderful! (641 reviews)

Great location in the heart of Rome. Most major attractions are within walking distance — about 25 minutes to the Vatican, Trevi Fountain, and Pantheon, 10 minutes to the Spanish Steps, and around 35 minutes to the Colosseum (or 15 minutes by metro). The staff were very friendly and welcoming, and our room was cleaned and the bed made every day. The hotel is clean, well presented, and located on the second floor. The shower was spacious and we appreciated the free water dispenser with reusable bottles provided. Breakfast is simple but enough to start the day. The only minor issues were that the ground floor buzzer didn’t seem to work on arrival, and the underside of the decorative bed runner had a stain. Overall, a comfortable stay in a very convenient location.

Reviewed on Mar 12, 2026

![Charme Spagna Boutique Hotel](https://images.trvl-media.com/lodging/19000000/18300000/18294700/18294667/78fddb84_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Charme Spagna Boutique Hotel

Rome City Centre

Save 100% on your flight

$2,456

per person

May 25 - Jun 1

found 17 hours ago

Roundtrip flight included

New York (NYC) to Rome (FCO)

9.2/10 Wonderful! (221 reviews)

Very clean, very helpful staff

Reviewed on Jan 27, 2026

![Palazzo Nainer](https://images.trvl-media.com/lodging/2000000/1040000/1037900/1037845/w3000h1997x0y0-eca3d01e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Palazzo Nainer

Rome City Centre

Save 100% on your flight

$2,491

per person

May 25 - Jun 1

found 17 hours ago

Roundtrip flight included

New York (NYC) to Rome (FCO)

9.4/10 Exceptional! (199 reviews)

Staff were wonderful! Breakfast was great. Very good location, too!

Reviewed on Feb 22, 2026

![Hotel Delle Civette](https://images.trvl-media.com/lodging/101000000/100970000/100969400/100969343/205f358e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Delle Civette

Nomentano

Save 100% on your flight

$1,702

per person

Jun 1 - Jun 7

found 10 hours ago

Roundtrip non-stop flight included

Los Angeles (LAX) to Rome (FCO)

9.6/10 Exceptional! (288 reviews)

Courteous and helpful staff. Clean, great amenities

Reviewed on Feb 8, 2026

## Where to stay in Policlinico

Find the best Policlinico areas and neighborhoods for the activities you enjoy most. [Learn more about Policlinico](https://expedia.com/Rome-Policlinico.dx6145020)

![Via del Corso which includes heritage architecture, heritage elements and street scenes](https://images.trvl-media.com/place/6147046/23c2bc21-bb33-4778-b64d-bbfa58503b1c.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Rome City Centre

8 out of top 10 points of interest in this area

4.5/5(3,994 area reviews)

 Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago. 

[Find hotel + flight trips in Rome City Centre](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Rome%20City%20Centre&DestID=553248633938945217&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Rome Historic Centre showing a statue or sculpture, a fountain and a square or plaza](https://images.trvl-media.com/place/6200441/57c34773-acbf-4b05-b5e7-9b3e692babe1.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Rome Historic Centre

5/5(1 area review)

 Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby. 

[Find hotel + flight trips in Rome Historic Centre](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Rome%20Historic%20Centre&DestID=6200441&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Trastevere showing street scenes as well as a couple](https://images.trvl-media.com/place/6046256/44314ce1-293d-46c2-8929-fc821edf8fc1.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Trastevere

4.5/5(411 area reviews)

 Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber. 

[Find hotel + flight trips in Trastevere](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Trastevere&DestID=6046256&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Monti which includes heritage elements, heritage architecture and a ruin](https://images.trvl-media.com/place/6185346/01855336-589e-456f-975e-2734b7e91944.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Monti

4.5/5(1,380 area reviews)

 Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts. 

[Find hotel + flight trips in Monti](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Monti&DestID=6185346&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Trevi which includes food and markets](https://images.trvl-media.com/place/553248634717495100/5af85b66-a718-45b6-9792-c4ffe84ee4d6.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Trevi

 Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station. 

[Find hotel + flight trips in Trevi](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Trevi&DestID=553248634717495100&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

## Policlinico Hotel Deals

![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/1c2ed679_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Quirinale

Via Nazionale 7 Rome RM

$210 nightly

$248 total

Mar 25 - Mar 26

Total with taxes and fees

8.6/10 Excellent! (1,941 reviews)

Everything was amazing here. The staff were kind and considerate, the breakfast was excellent and the location was prime!

Reviewed on Mar 15, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F25%2F2026&endDate=3%2F26%2F2026&selected=1058&PinnedHotelID=1058&HadPinnedHotel=true&regionId=6145020)

![Ruby Giulia Hotel Rome](https://images.trvl-media.com/lodging/115000000/114940000/114933100/114933055/960b9e99_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Ruby Giulia Hotel Rome

Via Agostino Depretis 45 Rome RM

Fully refundableReserve now, pay when you stay

$208 nightly

$243 total

Mar 31 - Apr 1

Total with taxes and fees

9.8/10 Exceptional! (56 reviews)

Very nice hotel location is great 10 min walk to colosseum new rooms had a great time

Reviewed on Mar 16, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F31%2F2026&endDate=4%2F1%2F2026&selected=114933055&PinnedHotelID=114933055&HadPinnedHotel=true&regionId=6145020)

![Hilton Garden Inn Rome Airport](https://images.trvl-media.com/lodging/2000000/1590000/1587200/1587154/78454e47_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hilton Garden Inn Rome Airport

Via Vittorio Bragadin 2 Fiumicino RM

Fully refundableReserve now, pay when you stay

$164 nightly

$191 total

Mar 30 - Mar 31

Total with taxes and fees

8.2/10 Very Good! (3,732 reviews)

Close to airport and has shuttle both ways

Reviewed on Mar 18, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F30%2F2026&endDate=3%2F31%2F2026&selected=1587154&PinnedHotelID=1587154&HadPinnedHotel=true&regionId=6145020)

[See all 16,209 properties in Policlinico](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F20%2F2026&endDate=3%2F21%2F2026&regionId=6145020)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Kid Friendly Vacations

[](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

LGBTQ Friendly Vacations

[](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adventure Vacations

[](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click)

![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Where to go when

[](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Honeymoon Vacations

[](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Mountain Vacations

[](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Fishing Vacations

[](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adults Only Vacations

[](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Waterpark Vacations

[](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Scuba Diving Vacations

[](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Yoga Vacations

[](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Cheap Vacations

[](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Solo Vacations

[](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click)

### Discover the most popular places to visit in Policlinico

![Illuminated Colosseum stands majestically in Rome at night with vibrant city life surrounding it](https://images.trvl-media.com/place/6046257/dfc1097b-fb0b-4d2f-96f5-15d86e72f134.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Colosseum

4.5/5(6,605 reviews)

A true architectural heavyweight, the 2,000-year-old Colosseum is often considered one of the seven “modern” wonders of the world.

[](https://expedia.com/Colosseum-Rome-City-Centre.d6046257.Vacation-Attraction)

![Visit Trevi Fountain, stunning baroque masterpiece in Rome, Italy under bright blue sky](https://images.trvl-media.com/place/6341167/4d1f5486-6de9-4b4a-9d04-d3a5db349148.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Trevi Fountain

4.5/5(6,182 reviews)

Rome is a city abundant in world-class water features, but none more stunning, or more famous, than the Trevi Fountain.

[](https://expedia.com/Trevi-Fountain-Rome-City-Centre.d6341167.Vacation-Attraction)

![Visit Pantheon in Rome and experience its ancient architecture and bustling atmosphere during a sunny day](https://images.trvl-media.com/place/502483/0d2ace47-fa09-4440-b2e6-a2a75b850d1e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Pantheon

4.5/5(5,436 reviews)

One of ancient Rome’s greatest achievements combines momentous history and inspired architecture.

[](https://expedia.com/Pantheon-Rome-City-Centre.d502483.Vacation-Attraction)

### Things to do

![Rome Hop-On Hop-Off Big Bus Tour](https://mediaim.expedia.com/localexpert/376190/27f7cb2b-8299-411e-bfc9-45c2f55e37d8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$36

per adult

**84%** of travellers recommend

[](https://expedia.com/things-to-do/rome-big-bus-hop-on.a376190.activity-details)

![Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica](https://mediaim.expedia.com/localexpert/1008396/d1b7fce5-e5c4-48ff-9148-df750d6ee6ce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$29

per adult

**90%** of travellers recommend

[](https://expedia.com/things-to-do/skip-the-line-group-tour-of-the-vatican.a1008396.activity-details)

![Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour](https://mediaim.expedia.com/localexpert/3138351/00713dcf-a749-4990-815b-c1abc113d09f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$82

per adult

**84%** of travellers recommend

[](https://expedia.com/things-to-do/rome-colosseum-with-arena.a3138351.activity-details)

[See all activities in Rome](https://expedia.com/things-to-do/search?rid=6145020)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.