San Francisco

Guayaquil

Things to do

Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

$118
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

$65
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Private city tour in Guayaquil - Iguana Park

Guayaquil Experience - Premium City Tour

$150
per adult
Guayaquil Experience - Premium City Tour
Cocoa farm and Chocolate making!

Cocoa farm and Chocolate making!

$155
per adult
Cocoa farm and Chocolate making!
Santa Ana Hill

Guayaquil City Tour Including the Light House of Cerro Santa Ana

$140
per adult
Guayaquil City Tour Including the Light House of Cerro Santa Ana
Half Day Walking Tour of Guayaquil Pearl of the Pacific

Half Day Walking Tour of Guayaquil Pearl of the Pacific

$100
per adult
Half Day Walking Tour of Guayaquil Pearl of the Pacific
See all activities in Guayaquil

San Francisco Hotel Deals

Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111 Guayaquil
$94 nightly
The price is $106 total per night from Aug 8 to Aug 9
$106 total
Aug 8 - Aug 9
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (941 reviews)
"Todo estuvo muy bien"

Reviewed on Jul 14, 2026

Hilton Colon Guayaquil
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
$85 nightly
The price is $96 total per night from Aug 8 to Aug 9
$96 total
Aug 8 - Aug 9
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (1,000 reviews)
"Parking is terrible"

Reviewed on Jul 13, 2026

Oro Verde Guayaquil
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
$110 nightly
The price is $123 total per night from Jul 31 to Aug 1
$123 total
Jul 31 - Aug 1
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,010 reviews)
"Nice located by the guayas River front ,breakfast very ample menú and TV at room with complete directo TV Chanels"

Reviewed on Jul 12, 2026

Wyndham Guayaquil Puerto Santa Ana
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
$91 nightly
The price is $102 total per night from Aug 7 to Aug 8
$102 total
Aug 7 - Aug 8
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,009 reviews)
"Great overnight stay. Lovely staff, excellent room and amenities and a great breakfast!"

Reviewed on Jul 14, 2026

Holiday Inn Guayaquil Airport by IHG
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406 Guayaquil Guayas
$70 nightly
The price is $80 total per night from Aug 15 to Aug 16
$80 total
Aug 15 - Aug 16
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
9.2/10 Wonderful! (1,009 reviews)
"Great place to stay for any occasion!"

Reviewed on Jul 14, 2026

Unipark by Oro Verde Hotels
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave Guayaquil Guayas
$80 nightly
The price is $90 total per night from Jul 26 to Jul 27
$90 total
Jul 26 - Jul 27
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,000 reviews)
"5 minutes de l’aéroport. Personnel aimable et très atentionné. 2 restaurants dont un situé au roof top. Chambre confortable."

Reviewed on Jul 6, 2026

Wyndham Garden Guayaquil
See all 438 properties in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Numa Pompilio Llona Street while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Chocolate Museum while you're in town.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or World Trade Center.

San Francisco

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