A rugged desert landscape with prominent red rock formations and sparse green vegetation.

San Luis Vacation Rentals

Check prices for these dates

In two weeks
Oct 2 - Oct 4
In two months
Nov 13 - Nov 15
In three months
Dec 11 - Dec 13
In four months
Jan 8 - Jan 10

Our top choices for San Luis vacation rentals

Room

1. 3-bedroom house in adorable San Luis with AC and comfort

3-bedroom house in adorable San Luis with AC and comfort
San Luis
$126 nightly
The price is $138
Sep 16 - Sep 17
Total with taxes and fees
3-bedroom house in adorable San Luis with AC and comfort
Exterior

2. Cozy 1-bedroom furnished studio in peaceful San Luis, AZ.

Cozy 1-bedroom furnished studio in peaceful San Luis, AZ.
San Luis
$130 nightly
The price is $142
Sep 16 - Sep 17
Total with taxes and fees
Cozy 1-bedroom furnished studio in peaceful San Luis, AZ.
Private kitchen

3. Guest House in the outskirts, Ranch living

Guest House in the outskirts, Ranch living
Somerton
8.4 out of 10, Very good, (7 reviews)
"Great stay for a single night. Very responsive host. Would stay again."
United States
Sharla M.
$92 nightly
The price is $97
Sep 18 - Sep 19
Total with taxes and fees
Guest House in the outskirts, Ranch living
Interior

4. One story fully furnished townhouse

One story fully furnished townhouse
Yuma
9.4 out of 10, Exceptional, (66 reviews)
"It was a really nice place :)"
United States
Danielle H.
$198 nightly
The price is $216
Sep 16 - Sep 17
Total with taxes and fees
One story fully furnished townhouse
Interior

5. Private room near YRMC. Ladies Only.

Private room near YRMC. Ladies Only.
Yuma
8.0 out of 10, Very good, (1 review)
"We enjoyed our stay. There were a couple of issues that the host was very helpful in trying to resolve (ie: the WIFI was down and she contacted the provider and got it running but it took a couple of days and the microwave did not work). The beds were very comfortable. The only suggestions I would make is that she add a coffee table or something to the living room and a bedside table in the bedrooms, There was nothing to set your phone, coffee, etc. on.Also the listing should specify that it is...
United States
Sari M.
$175 nightly
The price is $191
Sep 16 - Sep 17
Total with taxes and fees
Private room near YRMC. Ladies Only.
Private kitchen

6. Yuma Townhouse - Centrally Located!

Yuma Townhouse - Centrally Located!
Yuma
10.0 out of 10, Exceptional, (93 reviews)
"clean & very comfortable! would gladly stay again!"
United States
Emily W.
Yuma Townhouse - Centrally Located!
Terrace/patio

7. Private 1BR Guesthouse Retreat w/ Courtyard & Pool

Private 1BR Guesthouse Retreat w/ Courtyard & Pool
Yuma
$213 nightly
The price is $226
Sep 16 - Sep 17
Total with taxes and fees
Private 1BR Guesthouse Retreat w/ Courtyard & Pool
Terrace/patio

8. Yuma AZ|Relaxing King Bed

Yuma AZ|Relaxing King Bed
Yuma AZ
10.0 out of 10, Exceptional, (97 reviews)
"Great spot, loved exploring nearby parks!"
United States
Anonymous traveler
$65 nightly
The price is $71
Sep 16 - Sep 17
Total with taxes and fees
Yuma AZ|Relaxing King Bed
Interior

9. Vista del Valle

Vista del Valle
Vista Del Valle
10.0 out of 10, Exceptional, (152 reviews)
"Great place! We plan on staying again! "
United States
JESSICA F.
$213 nightly
The price is $233
Sep 27 - Sep 28
Total with taxes and fees
Vista del Valle
Property grounds

10. Historic Downtown Yuma · Monthly Stays · Bikes

Historic Downtown Yuma · Monthly Stays · Bikes
Downtown Yuma
10.0 out of 10, Exceptional, (16 reviews)
"Very clean snd comfortable. Great location. "
United States
Mark S.
$149 nightly
The price is $162
Oct 7 - Oct 8
Total with taxes and fees
Historic Downtown Yuma · Monthly Stays · Bikes
Private kitchen

11. Remodeled Yuma Condo close to YRMC Hospital

Remodeled Yuma Condo close to YRMC Hospital
Yuma
9.0 out of 10, Wonderful, (10 reviews)
"Came to Yuma to visit with Friends and enjoy the warmth (since I live in ND). Perfect place and location to stay."
United States
Laura P.
Remodeled Yuma Condo close to YRMC Hospital
Interior

12. Lovely 2-bedroom house in the heart of Yuma - Pet Friendly!

Lovely 2-bedroom house in the heart of Yuma - Pet Friendly!
Yuma
$163 nightly
The price is $177
Sep 16 - Sep 17
Total with taxes and fees
Lovely 2-bedroom house in the heart of Yuma - Pet Friendly!
Private kitchen

13. New Modern home w/RV access and Garage Access.

New Modern home w/RV access and Garage Access.
Yuma
10.0 out of 10, Exceptional, (14 reviews)
"The house, the property, the host and the furniture ( interior design)were awesome! The whole experience was amazing!!"
United States
Richard P.
$271 nightly
The price is $297
Sep 17 - Sep 18
Total with taxes and fees
New Modern home w/RV access and Garage Access.
Interior

14. The Hillside Hacienda located in the heart of Yuma. Hospital Nearby.

The Hillside Hacienda located in the heart of Yuma. Hospital Nearby.
Yuma
9.6 out of 10, Exceptional, (5 reviews)
"A clean, functional place to stay in a quiet central neighborhood that was great for evening walks. The host answered our minor questions promptly.I highly recommend for stays in Yuma."
Canada
Jude T.
$284 nightly
The price is $310
Sep 21 - Sep 22
Total with taxes and fees
The Hillside Hacienda located in the heart of Yuma. Hospital Nearby.
Private kitchen

15. Tranquil 3-bedroom house with AC in charming Yuma

Tranquil 3-bedroom house with AC in charming Yuma
Yuma
10.0 out of 10, Exceptional, (11 reviews)
"It was a charming place to stay. "
United States
Shannon P.
$211 nightly
The price is $231
Sep 17 - Sep 18
Total with taxes and fees
Tranquil 3-bedroom house with AC in charming Yuma
Pool

16. 3BR Yuma Condo Pool & Pets Welcome Free

3BR Yuma Condo Pool & Pets Welcome Free
Vista Del Valle
$267 nightly
The price is $293
Sep 16 - Sep 17
Total with taxes and fees
3BR Yuma Condo Pool & Pets Welcome Free
Room

17. Pet-Friendly, Charming bungalow with WiFi and AC in sunny Yuma

Pet-Friendly, Charming bungalow with WiFi and AC in sunny Yuma
Yuma Townsite
10.0 out of 10, Exceptional, (3 reviews)
"Cute little place. Exactly as I was expecting."
United States
Janet K.
$101 nightly
The price is $111
Sep 22 - Sep 23
Total with taxes and fees
Pet-Friendly, Charming bungalow with WiFi and AC in sunny Yuma
Interior

18. Queen Bed|Nsmk|Yuma AZ

Queen Bed|Nsmk|Yuma AZ
Yuma Townsite
10.0 out of 10, Exceptional, (69 reviews)
"Memorable stay, everything was just right for a family getaway!"
United States
Anonymous traveler
$79 nightly
The price is $85
Sep 16 - Sep 17
Total with taxes and fees
Queen Bed|Nsmk|Yuma AZ
Exterior

19. Private Desert Oasis / Pool, Arcade, Grill & RV Parking / 4 bedroom 2 bath Home

Private Desert Oasis / Pool, Arcade, Grill & RV Parking / 4 bedroom 2 bath Home
Yuma East
9.8 out of 10, Exceptional, (40 reviews)
"Great property, responsive host, highly recommend!"
United States
Alisa D.
$429 nightly
The price is $455
Sep 21 - Sep 22
Total with taxes and fees
Private Desert Oasis / Pool, Arcade, Grill & RV Parking / 4 bedroom 2 bath Home
Private kitchen

20. 3-bedroom house with AC, WiFi, in the center of the city

3-bedroom house with AC, WiFi, in the center of the city
Casitas Del Valle
9.6 out of 10, Exceptional, (9 reviews)
"Very clean house, comfortable beds, great location. "
United States
Reed S.
$214 nightly
The price is $234
Sep 19 - Sep 20
Total with taxes and fees
3-bedroom house with AC, WiFi, in the center of the city
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Luis Hotel Reviews

Residence Inn By Marriott Yuma

Residence Inn By Marriott Yuma

10/10 Excellent
"Room was clean, staff was very helpful and friendly. Air conditioning system was noisy even when turned off. Other than that very happy with the room and facilities."
Michael Sean 2-night trip
Posted 9 hours ago
Residence Inn By Marriott Yuma

Find out more about San Luis

Everything you need to know about San Luis vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the San Luis vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect San Luis vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

San Luis vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in San Luis. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit San Luis in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $97 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on San Luis rentals

At Expedia, we put the best San Luis vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top San Luis rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream San Luis vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around San Luis. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in San Luis?

Yes, we give you a choice of vacation rentals near popular local attractions in San Luis, or you can select a more secluded option if you're looking for relaxation. San Luis is known for its parks.

What's the top vacation rental in San Luis?

Picacho Pool House - NO Cleaning or Extra Guest Fees: Visitors like this San Luis vacation home rental. It offers a fireplace, a hot tub, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a stovetop, and a microwave, so you can cook with friends or family.

How many vacation rentals are there in San Luis?

Choose from 5 Expedia vacation rentals in San Luis for a memorable vacation.

What can I see and do in San Luis?

Explore the area and family-friendly sights such as Z Fun Factory, or get out into nature at a spot like Colorado River. In the larger area, you’ll find San Luis Lakes State Park and Garita Entrance to Mexico.

What are vacation rentals like in San Luis?

Vacation rentals are privately owned properties you can book for a couple days or more in San Luis. Vacation rentals provide amenities like kitchens and laundry facilities so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can provide a sense of seclusion away from public hotel elevators and busy concierge desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great option for family gatherings.