San Luis Vacation Rentals

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Our top choices for San Luis vacation rentals

$44 nightly
The price is $44
Dec 14 - Dec 15
Espacio Limpio, Agradable y Cómodo

Houseboat in Guatapé

La trinidad
3.5 star property
9.4 out of 10, Exceptional, (28)
"Great place to stay and real reasonable for a glamping trip as a couple!"
United States
George
La trinidad
10.0 out of 10, Exceptional, (1)
"Cozy retreat for relax, romance, meditation or just to spoil yourself. Staff and location are great. Boat condition is mint and the whole experience is very warming."
United States
yahkoh
$133 nightly
The price is $133
Dec 14 - Dec 15
Romantic houseboat in nature and enjoy the simplicity of this quiet accommodation
$115 nightly
The price is $115
Dec 14 - Dec 15
Romantic houseboat in nature and enjoy the simplicity of this quiet accommodatio

Chalet in El Peñol

KABINE
3.0 star property
10.0 out of 10, Exceptional, (2)
"Genial"
Colombia
Daniel
$160 nightly
The price is $160
Dec 21 - Dec 22
KABINE

Cabin in Guatapé

Cardinal Glamping
3.5 star property
Cardinal Glamping

Cabin in Guatapé

Ecoedén Glamping
3.0 star property
10.0 out of 10, Exceptional, (11)
"The host and staff were friendly and attentive. The view was incredible "
United States
Williiam
Ecoedén Glamping
2.0 star property
$113 nightly
The price is $113
Dec 14 - Dec 15
Nativa Ecohotel - Laguna de San Diego

Aparthotel in San Rafael

Finca hotel Sendero del rio
2.5 star property
8.8 out of 10, Excellent, (3)
"Wonderful place to relax and communicate with nature very peaceful "
United States
ana
$67 nightly
The price is $67
Dec 24 - Dec 25
Finca hotel Sendero del rio

Cabin in Guatapé

GRETEL CHALETS SUIZO
3.5 star property
10.0 out of 10, Exceptional, (7)
"Beautiful place and ideal for a unforgettable moment!! Great service!!"
United States
Azaias
$147 nightly
The price is $147
Dec 18 - Dec 19
GRETEL CHALETS SUIZO

Apartment in Guatapé

Casa García Rent Home
3.5 star property
7.2 out of 10, Good, (7)
"Besides the lovely family hosting a more beautiful location with the vistas would be hard to imagine the only challenges to drive based on weather conditions, and the host is more gracious to also meet us on the main street and have a follow him"
United States
Stephen
Casa García Rent Home
3.0 star property
$29 nightly
The price is $29
Dec 14 - Dec 15
Habitacion monarca - adosada

Cabin in El Peñol

Magic View Guatape
3.5 star property
$116 nightly
The price is $116
Dec 14 - Dec 15
Magic View Guatape

Cabin in Guatapé

Hotel Mito Guatapé
3.0 star property
$77 nightly
The price is $77
Dec 14 - Dec 15
Hotel Mito Guatapé

Apartment in Guatapé

Guatape Lake view
3.0 star property
8.8 out of 10, Excellent, (8)
"Love it the attention place my booking where they n really quick pick up they keys they show us the apartment all great and equip only think complicate was the heater in the showers other than that we love the place "
United States
Kermit
$76 nightly
The price is $76
Dec 16 - Dec 17
Guatape Lake view

Cabin in Guatape

Andre's Deck
2.0 star property
10.0 out of 10, Exceptional, (1)
"We had a great time at Andres’ cabin! He and his family are so hospitable! They live on the property so they are available if you need anything. It’s a really lovely view of the lake from inside the cabin and he provides an extra blanket to stay warm if you want to lay on the nets outside. It’s a super tranquil place and if you’re interested in watching birds they love watching them in the morning and know a ton about them so you can probably go up to the main house and watch with them or just...
United States
Leah P.
$62 nightly
The price is $62
Dec 15 - Dec 16
Andre's Deck

Aparthotel in Puerto Triunfo

Villa Mediterranea
2.0 star property
8.0 out of 10, Very Good, (5)
"New apartment, everything was clean and bed was super comfortable, I’ll recommend staying here"
United States
Mayra
$60 nightly
The price is $60
Dec 18 - Dec 19
Villa Mediterranea

Cabin in Guatapé

Sotavento Cabañas
3.0 star property
9.8 out of 10, Exceptional, (51)
"Food great,very accommodating, great massages and the luxury cabin was beautiful "
Canada
Derrick
$161 nightly
The price is $161
Dec 25 - Dec 26
Sotavento Cabañas

Apartment in Guatapé

La Martinera Plaza Principal
3.5 star property
9.0 out of 10, Wonderful, (25)
"I will came back next year, everything is near by, very nice place to stay "
United States
H Antonio
$45 nightly
The price is $45
Jan 13 - Jan 14, 2026
La Martinera Plaza Principal
2.5 star property
8.0 out of 10, Very Good, (2)
$80 nightly
The price is $80
Dec 17 - Dec 18
Luum Glamping by Roots Rentals
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Luis Hotel Reviews

Find out more about San Luis

Everything you need to know about San Luis vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the San Luis vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect San Luis vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

San Luis vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in San Luis. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit San Luis in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $29 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on San Luis rentals

At Expedia, we put the best San Luis vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top San Luis rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream San Luis vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around San Luis. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in San Luis?

Yes, we have vacation rentals close to top points of interest in San Luis, or you can choose a more remote option if you want a relaxing place to stay.

What are some of the best vacation rentals in San Luis?

Finca San Fernando El peñol-Guatape: This vacation home rental near San Luis has a Smart TV and WiFi to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms and a kitchen with a fridge.

What’s there to see and do in San Luis?

While exploring the area, visit family-friendly sights like Parque Comfama, or get outside and enjoy nature at La Planta Waterfall. In the larger area, you’ll find El Balseadero Nature Park and Natural Reserve Canondel Rio Claro.

What’s a vacation rental in San Luis like?

A vacation rental is a private property you can book for a few weeks or just a few days in San Luis. Vacation rentals provide amenities like kitchens and laundry facilities so you'll be comfy for your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of seclusion away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for family gatherings.