Title: Top 10 Hotels in Santa María Centro from $101 - Competitive Prices | Expedia.com

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## Check prices for these dates

Tonight

[Feb 5 - Feb 6](https://www.expedia.com/Hotel-Search?regionId=553248635923647958&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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This weekend

[Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=553248635923647958&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

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## Our top choices for Santa María Centro hotels

![Outdoor spa tub](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/eae29abe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/25391e01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/fe30d3b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness studio](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/w3248h3120x0y0-30cfe3d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Amerian Rafaela Hotel

[](https://www.expedia.com/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information)

Rafaela

9.0/10

Wonderful

(47 reviews)

"Nice hotel and staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Felix

$101 nightly

$101 total

Feb 18 - Feb 19

[](https://www.expedia.com/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Santa María Centro Hotel Reviews

![Amerian Rafaela Hotel](https://images.trvl-media.com/lodging/40000000/39380000/39371100/39371095/5de82f5d_y.jpg)

### Amerian Rafaela Hotel

6/10 Okay

"The shower box is leaking water to outside. The vent installed in the toilette is very noisy. The outlet frame located on the wall at the desk area is lose and was falling when used. Cleaning was good. "

[](https://expedia.com/Rafaela-Hotels-Amerian-Rafaela-Hotel.h39371095.Hotel-Information)

## More cheap stays in Santa María Centro

![Parra Hotel& Suites](https://images.trvl-media.com/lodging/16000000/15470000/15462700/15462633/460a619a_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Parra Hotel& Suites

BV. SANTA FE 554,Rafaela, Santa Fe, Argentina Rafaela Santa Fe Province

[Get rates](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=15462633&PinnedHotelID=15462633&HadPinnedHotel=true&regionId=553248635923647958)

[](https://expedia.com/Rafaela-Hotels-Parra-Hotel-Suites.h15462633.Hotel-Information)

## Frequently asked questions

### What is the best area to stay in Santa María Centro?

> This area serves as the heart of Santa María, offering a convenient and pleasant experience for visitors. It's characterized by its tree-lined streets, historic buildings, and a concentration of shops, restaurants, and cultural institutions. Plaza San Martín is the main public square, often bustling with activity and surrounded by important landmarks.
> 
>   
> Couples will find this area ideal for a relaxed and enjoyable trip. You're within walking distance of many local eateries, boutique stores, and the beautiful architecture of the Cathedral Metropolitana. Evening strolls through the plaza or along pedestrian-friendly streets offer a pleasant way to experience the city.
> 
>   
> Solo travelers will also appreciate the ease and accessibility of this central location. It's simple to navigate on foot, allowing for independent exploration of galleries and cafes.

### When is the best time to go to Santa María Centro?

> During these seasons, you'll experience mild temperatures and less humidity, making it comfortable for walking around the city's plazas and historic sites. Spring brings blooming jacaranda trees, adding a beautiful touch to the city, while autumn offers crisp air and comfortable days.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Santa María Centro hotel booking with Expedia?

> \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

### How much is the nightly rate at a Santa María Centro hotel?

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