Find hotels in Santa Maria, Guayaquil

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Discover Santa Maria hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

DC Suites Aeropuerto
Lobby

DC Suites Aeropuerto

3.0 star property
9.0 out of 10, Wonderful, (552)
"Staff was very friendly and had a quick check-in. Loved the cat in the lobby."
$36 nightly
The price is $37
Sep 8 - Sep 9
DC Suites Aeropuerto
Hotel La Ria Durán
Premium bedding, desk, laptop workspace, iron/ironing board

Hotel La Ria Durán

3.0 star property
7.2 out of 10, Good, (19)
$46 nightly
The price is $46
Sep 8 - Sep 9
Hotel La Ria Durán
Hotel Puerto Pacifico Guayaquil Airport
Massages

Hotel Puerto Pacifico Guayaquil Airport

4.0 star property
8.8 out of 10, Excellent, (207)
"Nice staff - clean & modern facilities & good breakfast buffet (& included w my booking)."
Hotel Puerto Pacifico Guayaquil Airport
Holiday Inn Guayaquil Airport by IHG
Outdoor pool

Holiday Inn Guayaquil Airport by IHG

3.5 star property
9.2 out of 10, Wonderful, (1002)
"Very nice hotel and close to the airport."
$101 nightly
The price is $114
Sep 26 - Sep 27
Holiday Inn Guayaquil Airport by IHG
Hotel Patrimonial by Greenfield
Outdoor pool, sun loungers

Hotel Patrimonial by Greenfield

3.5 star property
8.6 out of 10, Excellent, (123)
"Friendly staff. I got moved to a more convenient room with no issues."
Hotel Patrimonial by Greenfield
MC Suites
Lobby sitting area

MC Suites

3.5 star property
8.2 out of 10, Very Good, (131)
"Great place!!!!!!"
$65 nightly
The price is $66
Sep 10 - Sep 11
MC Suites
Iguanazu Bed & Breakfast
Exterior

Iguanazu Bed & Breakfast

3.5 star property
9.2 out of 10, Wonderful, (46)
"Swimming pool"
$92 nightly
The price is $105
Oct 5 - Oct 6
Iguanazu Bed & Breakfast
Doubletree By Hilton Guayaquil
In-room safe, blackout drapes, soundproofing, iron/ironing board

Doubletree By Hilton Guayaquil

3.5 star property
9.2 out of 10, Wonderful, (46)
"The staff is amazing and the hotel is so beautiful."
$72 nightly
The price is $80
Sep 21 - Sep 22
Doubletree By Hilton Guayaquil
Mansión del Río
Lobby lounge

Mansión del Río

3.5 star property
8.6 out of 10, Excellent, (127)
"This place is amazing: An old building with old furnishing (pictures, photos, furniture décor), full of character. The neighbourhood is very safe, with lots of restaurants and bars (as well as some shops, art galleries, even a theatre) in very easy reach, and an easy walk from the Malecón and downtown Guayaquil. The staff were very helpful. Breakfast was fine. But again, it is the building that is the star here: an exceptional place in an exceptional location. Highly recommended."
$59 nightly
The price is $66
Sep 8 - Sep 9
Mansión del Río
Oro Verde Guayaquil
Children's activities

Oro Verde Guayaquil

5.0 star property
9.4 out of 10, Exceptional, (1003)
"Beautiful and staff was exceptional!! "
$99 nightly
The price is $111
Sep 14 - Sep 15
Oro Verde Guayaquil
MundialCity Hotel Guayaquil
Outdoor pool, sun loungers

MundialCity Hotel Guayaquil

3.0 star property
8.4 out of 10, Very Good, (162)
"everything great "
MundialCity Hotel Guayaquil
Ibis Styles El Malecon Guayaquil
Exterior

Ibis Styles El Malecon Guayaquil

4.0 star property
9.4 out of 10, Exceptional, (240)
"This hotel is a good value for your money..."
$60 nightly
The price is $68
Sep 12 - Sep 13
Ibis Styles El Malecon Guayaquil
Grand Hotel Guayaquil, an Ascend Collection Hotel
Outdoor pool, open 8:00 AM to 9:00 PM, sun loungers

Grand Hotel Guayaquil, an Ascend Collection Hotel

4.0 star property
9.2 out of 10, Wonderful, (941)
"The hotel and staff were great. "
$68 nightly
The price is $76
Sep 21 - Sep 22
Grand Hotel Guayaquil, an Ascend Collection Hotel
Unipark by Oro Verde Hotels
Reception

Unipark by Oro Verde Hotels

4.0 star property
9.2 out of 10, Wonderful, (1001)
"Updated building recently bought by oro verde hotels group Great breakfast!"
$72 nightly
The price is $82
Sep 21 - Sep 22
Unipark by Oro Verde Hotels
Wyndham Guayaquil Puerto Santa Ana
Presidential Suite, 1 King Bed, Jetted Tub, River View | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Wyndham Guayaquil Puerto Santa Ana

4.5 star property
9.2 out of 10, Wonderful, (1003)
"Nice place, friendly staff and safe to walk around!!"
$110 nightly
The price is $123
Sep 21 - Sep 22
Wyndham Guayaquil Puerto Santa Ana
Casa Serena
Double Room | 1 bedroom, premium bedding, minibar, iron/ironing board

Casa Serena

2.5 star property
9.4 out of 10, Exceptional, (52)
"I was pleased to find this place thank you, had a great experience."
Casa Serena
Luxva Hotel Boutique
Exterior

Luxva Hotel Boutique

3.0 star property
9.4 out of 10, Exceptional, (159)
"Friendly staff. "
$70 nightly
The price is $71
Sep 16 - Sep 17
Luxva Hotel Boutique
Radisson Hotel Guayaquil
Outdoor pool, sun loungers

Radisson Hotel Guayaquil

5.0 star property
9.2 out of 10, Wonderful, (606)
"It was great"
$76 nightly
The price is $86
Sep 14 - Sep 15
Radisson Hotel Guayaquil
Wyndham Garden Guayaquil
Rooftop bar, alfresco dining, open daily

Wyndham Garden Guayaquil

3.5 star property
9.0 out of 10, Wonderful, (1003)
"Very nice place, clean, kind staff, good location "
$80 nightly
The price is $90
Sep 14 - Sep 15
Wyndham Garden Guayaquil
Tropical Inn
Outdoor pool

Tropical Inn

2.0 star property
8.6 out of 10, Excellent, (9)
"for the price was good"
$25 nightly
The price is $25
Sep 8 - Sep 9
Tropical Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and La Perla while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

Kennedy

1 out of top 10 points of interest in this area

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

Top Santa Maria Hotel Reviews

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Frequently asked questions

Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Maria.
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How much is the nightly rate at a Santa Maria hotel?
Hotel prices in Santa Maria often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.