Name: Comfort Inn & Suites Regional Medical Center
Price range: $125 total
Rating: 8.2

Popular places to visit

While on a recent family roadtrip I stumbled across this amazing stained glass on the campus.
I was driving to a different area to go shooting and felt obligated to stop and shoot this amazing work!
I love exploring unfamiliar areas to find these photographic gems!

Hardin Simmons University

Take a campus tour or just explore the area of Hardin Simmons University, during your travels in Abilene. Experience the entertainment venues and theater scene in this family-friendly area.

Rose Park Tennis Center

Catch an event at Rose Park Tennis Center during your trip to Abilene.

Abilene Christian University

Take a campus tour or just explore the area of Abilene Christian University, during your travels in Abilene. Discover the cocktail bars and entertainment venues in this family-friendly area.

Dyess Air Force Base

Dyess Air Force Base is just one of the places to see in Abilene, so why not enjoy the other things to explore during your travels? Discover the cocktail bars and entertainment venues in this trendy area.

Mall of Abilene

You can enjoy retail therapy at Mall of Abilene during your trip to Abilene. Discover the cocktail bars and entertainment venues in this family-friendly area.

Abilene Zoo

See the exotic and native animals who live at Abilene Zoo during your trip to Abilene. Discover the cocktail bars and entertainment venues in this trendy area.

Sayles Blvd. Area Hotel Deals

The Hideout - A Sayles Ranch Guesthouse

Abilene

$182 nightly

$206 total

Oct 19 - Oct 20

Total with taxes and fees

Stay at this guesthouse in Abilene. Enjoy a water park, patios, and an in-room coffeemaker. Popular attractions Rose Park Tennis Center and Amy Graves Ryan Little ...

9.4/10 Exceptional! (6 reviews)

"Quiet"

Reviewed on Jun 16, 2025

Eleven South: One - Modern Studio Apartment

Abilene, TX

$237 nightly

$267 total

Oct 27 - Oct 28

Total with taxes and fees

Stay at this vacation home in Abilene. Enjoy a water park. Popular attractions Amy Graves Ryan Little Theatre and Rose Park Tennis Center are located ...

Three Bedroom, Historic, Charming Spanish Villa in Abilene TX!

Abilene

$358 nightly

$376 total

Oct 6 - Oct 7

Total with taxes and fees

Stay at this vacation home in Abilene. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attractions Rose Park Tennis Center and Amy Graves ...

10/10 Exceptional! (24 reviews)

"This home was impeccably restored to its historical promenance. Our friend staying with us is an architect and loved the attention to the detail to the homes restoration and added space. The home was well appointeded with all ameneties. It was a comfortable well lived in environment. The furnishings ..."

Reviewed on Sep 26, 2025

MCM Elegante Suites Abilene

4250 Ridgemont Dr, Abilene, TX

$156 nightly

$180 total

Oct 5 - Oct 6

Total with taxes and fees

Stay at this 3-star hotel in Abilene. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...

8.8/10 Excellent! (1,000 reviews)

"Family friendly and happy hour!"

Reviewed on Sep 30, 2025

Big Country Hotel & Suites, SureStay Collection by BW

3010 Catclaw Drive, Abilene, TX

$117 nightly

$135 total

Oct 19 - Oct 20

Total with taxes and fees

Book a stay at this business-friendly hotel in Abilene. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

8.2/10 Very Good! (1,016 reviews)

"Good place, clean and organized, however the internet wasn't working during all the time I stayed"

Reviewed on Sep 29, 2025

Comfort Inn & Suites Regional Medical Center

6350 Directors Pkwy, Abilene, TX

$108 nightly

$125 total

Oct 5 - Oct 6

Total with taxes and fees

Book a stay at this business-friendly hotel in Abilene. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

8.2/10 Very Good! (976 reviews)

"Not bad except breakfast not enough and we let them know at the service desk and he’s like ok"

Reviewed on Sep 29, 2025

See all 269 properties in Sayles Blvd. Area

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Sayles Blvd. Area

SoDA District

Though SoDA District might not have many top sights, you can venture to the surrounding area to see attractions like Grace Museum and Paramount Theatre.

Downtown Abilene

While visiting Downtown Abilene, you might make a stop by sights like Grace Museum and Paramount Theatre.

Over Place Area

Though Over Place Area might not have many top sights, you can venture to the surrounding area to see attractions like Mall of Abilene and Grace Museum.

Elmwood Area

3.5/5(2 area reviews)

While Elmwood Area might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Dyess Air Force Base and Mall of Abilene.

Original Town North

While visiting Original Town North, you might make a stop by sights like Paramount Theatre and Grace Museum.

See our Where To Stay guide

Unlock instant savings with Member Prices

Sayles Blvd. Area, TX

Abilene

Visit Sayles Blvd. Area

Popular places to visit

Hardin Simmons University

Rose Park Tennis Center

Abilene Christian University

Dyess Air Force Base

Mall of Abilene

Abilene Zoo

Sayles Blvd. Area Hotel Deals

The Hideout - A Sayles Ranch Guesthouse

Eleven South: One - Modern Studio Apartment

Three Bedroom, Historic, Charming Spanish Villa in Abilene TX!

MCM Elegante Suites Abilene

Big Country Hotel & Suites, SureStay Collection by BW

Comfort Inn & Suites Regional Medical Center

Check Sayles Blvd. Area hotel availability

Other neighborhoods around Sayles Blvd. Area

SoDA District

Downtown Abilene

Over Place Area

Elmwood Area

Original Town North

Sayles Blvd. Area, TX

Travelers

Room 1