$74 Car Rental Palmyra, MO

Reasons to book a car rental in and around Palmyra

Renting a car in Palmyra provides the freedom and flexibility to explore attractions at your own pace. With a rental vehicle, you can easily visit local highlights such as Big Spring Park, an urban park perfect for outdoor experiences, and the Gardner House Museum, which offers cultural insights. For those seeking a scenic escape, Murphy Island is a delightful destination nearby. A rental car also allows you to venture to popular nearby cities, including Hannibal, located 10 miles away, where you can explore the Mark Twain Boyhood Home and Museum and the Mark Twain Cave. Quincy, just 11 miles from Palmyra, features attractions like Villa Katherine Castle and Washington Park, while Rensselaer, 9 miles away, offers Bear Creek Park and Indian Mounds Park. Whether you're traveling with family, managing luggage, or planning romantic outings, having a car makes it convenient to move between these diverse experiences. Enjoy the ease of managing your travel plans and ensuring you see all that this charming area has to offer.

Where to stay around Palmyra

• Hannibal: Located 10 miles away from Palmyra, Hannibal offers a romantic experience with its scenic outdoor attractions. Visitors can explore the historic Mark Twain Boyhood Home and Museum, venture into the Mark Twain Cave for outdoor adventures, or admire the architecture of Rockcliffe Mansion. In addition, Hannibal has various dining options, including local wineries and restaurants, making it a great base for your stay.
• Quincy: Situated 11 miles from Palmyra, Quincy provides a blend of culture and outdoor experiences. Key attractions include the historic Villa Katherine Castle and Washington Park, perfect for leisurely strolls. Quincy is also home to shopping centers and educational venues, alongside a selection of wineries and restaurants, offering diverse dining options for travelers.
• Monroe City: About 15 miles from Palmyra, Monroe City is ideal for those seeking outdoor and romantic activities. Mark Twain Lake is a beautiful spot for scenic views and relaxation, while Mark Twain State Park offers adventure and exploration opportunities. The area features local wineries and restaurants, ensuring pleasant dining experiences during your stay.

10 tips to save on your car rental in and around Palmyra

Finding the cheapest car rentals in Palmyra

Using our Search Wizard

If the deals that are available on our page do not suit your needs, then enter Palmyra into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Palmyra and provide you with a list of the cheapest options, with no added fees.

Renting a car in Palmyra

Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Palmyra. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.

Expected prices in Palmyra

Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $74.

Flexibility & Cancellation

Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.

We all love being rewarded

One Key members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today.

Car classes available from Expedia in 2026

The classes of vehicles available will change depending on your chosen location.

• Compact car rentals    
• Convertible car rentals    
• Economy car rentals    
• Fullsize car rentals    
• Luxury car rentals
• Midsize car rentals    
• Mini car rentals    
• Minivan rentals    
• Pickup car rentals    
• Premium car rentals
• Sportscar rentals    
• Standard car rentals    
• SUV rentals    
• Van rentals