Charleston Vacation Rentals

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Our top choices for Charleston vacation rentals

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Cape Girardeau
9.6 out of 10, Exceptional, (44)
"This place is AWESOME! It's clean, artsy, fun, and if we ever have a chance, we will certainly return!"
United States
Jordan S.
$132 nightly
The price is $138
Dec 14 - Dec 15
Total with taxes and fees
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau
Cape Girardeau
10.0 out of 10, Exceptional, (28)
"Great property and a super host! He was super helpful and always willing to help with any questions we had. Would definitely rent here again!"
United States
Mark M.
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (35)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
$133 nightly
The price is $140
Dec 22 - Dec 23
Total with taxes and fees
Cozy cabins on beautiful Horseshoe Lake

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.6 out of 10, Excellent, (48)
"Some issues with check-in. Very nice area. Lot of history."
United States
Jeffrey M.
$101 nightly
The price is $101
Dec 14 - Dec 15
Total with taxes and fees
Little Blue Cottage on Spanish

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (20)
"cute A frame in a secluded spot. Couldn’t ask for a more relaxing situation. "
United States
Jason M.
Peaceful secluded cabin located near Horseshoe Lake

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (3)
"Cute place, clean and spacious. Convenient location. Very nice stay! Would stay again. "
United States
Rebecca E.
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.6 out of 10, Excellent, (36)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
United States
Emily D.
$206 nightly
The price is $214
Dec 15 - Dec 16
Total with taxes and fees
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi
Cape Girardeau
10.0 out of 10, Exceptional, (10)
"A large and comfortable house with cool historical details and just about everything you need to have a great, easy, smooth-running vacation. Great location for downtown exploring."
United States
Virginia C.
Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.2 out of 10, Wonderful, (25)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
$133 nightly
The price is $140
Dec 21 - Dec 22
Total with taxes and fees
The Rested Duck Mallard Room

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Kevil
10.0 out of 10, Exceptional, (185)
"Very clean and comfortable stay in the country"
United States
Joe S.
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

River's Dawn - Modernized Historic Home - River Views - King Bed - Fast Wifi

River's Dawn - Modernized Historic Home - River Views - King Bed - Fast Wifi
Cape Girardeau
10.0 out of 10, Exceptional, (4)
"The home was beautiful inside and very clean. The bed was comfortable, and the area was quiet. My father and I really enjoyed our stay. I would stay there again over anywhere else I have stayed in cape. "
United States
Shawn
River's Dawn - Modernized Historic Home - River Views - King Bed - Fast Wifi

Quaint, Beautiful Home next to SEMO and Hospital

Quaint, Beautiful Home next to SEMO and Hospital
Cape Girardeau
9.8 out of 10, Exceptional, (43)
"Location was perfect. The house was clean and met all our needs. Would definitely stay here again in the future."
United States
Beau L.
Quaint, Beautiful Home next to SEMO and Hospital

Need a cozy winter getaway or base camp for duck and deer hunters? We got you!

Need a cozy winter getaway or base camp for duck and deer hunters? We got you!
2.0 star property
Tamms
10.0 out of 10, Exceptional, (23)
"Great place to stay, nice people"
United States
Jack W.
Need a cozy winter getaway or base camp for duck and deer hunters? We got you!

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (148)
"Such a great place and location"
United States
Tracy H.
$229 nightly
The price is $245
Dec 14 - Dec 15
Total with taxes and fees
Serenity South -- Gardens, River-Views, and Refreshing Space

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (7)
"Nice place, great times"
United States
Jace W.
$422 nightly
The price is $438
Dec 15 - Dec 16
Total with taxes and fees
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau
10.0 out of 10, Exceptional, (223)
"Property location was perfect.Deck view was great.Very clean and comfortable place."
United States
Robert M.
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Urban 2-bedroom Escape in Downtown Cape Girardeau

Urban 2-bedroom Escape in Downtown Cape Girardeau
Cape Girardeau
10.0 out of 10, Exceptional, (9)
"Great house in a great location. Well-stocked kitchen with some thoughtful extras. You can tell that the owner cares which means a lot to someone originally from Cape. 10/10 would stay again."
United States
Elizabeth C.
Urban 2-bedroom Escape in Downtown Cape Girardeau

Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
Cape Girardeau
9.0 out of 10, Wonderful, (22)
"Enjoyed by all! Relaxing and plenty to do. Very clean and comfortable!"
United States
Terresa V.
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

Charming 3-bedroom house near downtown

Charming 3-bedroom house near downtown
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (2)
"My husband and I along with one other couple stayed here while in Cape for a wedding. The location was nice and was a short distance for driving or Ubering around town. The price was great!! Highly recommend."
United States
Danielle U.
Charming 3-bedroom house near downtown

Downtown Cape 2 Bdrm/2 Bath Apt, Cozy & Walkable

Downtown Cape 2 Bdrm/2 Bath Apt, Cozy & Walkable
Cape Girardeau
9.0 out of 10, Wonderful, (2)
"Great location and the one issue was resolved quickly and no fault of the property owner. "
United States
Kevin S.
Downtown Cape 2 Bdrm/2 Bath Apt, Cozy & Walkable
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Charleston Hotel Reviews

Find out more about Charleston

Everything you need to know about Charleston vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Charleston vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Charleston vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Charleston vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Charleston. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Charleston in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $101 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Charleston rentals

At Expedia, we put the best Charleston vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Charleston rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Charleston vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Charleston. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Charleston?

Yes, we have vacation rentals close to the most popular sights in Charleston, or you can go with a secluded option if you want a relaxing place to stay. Our travelers say Charleston has a good selection of restaurants. Make sure you have time to check out the entertainment choices and theaters during your trip.

What are some of the best vacation rentals that Charleston has to offer?

Little Blue Cottage on Spanish: You might want to consider this vacation home rental near Charleston, which comes with WiFi so you can feel at home during your trip.

What can I see and do in Charleston?

Mississippi River and Ohio River are a couple of lovely local spots to get outside and enjoy nature. Central Park and Ballard Wildlife Management Area are a couple of places you'll find in the larger area.

What are vacation rentals like in Charleston?

Vacation rentals are private accommodations you can book for a few days or a quick weekend in Charleston. Vacation rentals feature extras like WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from shared hotel elevators and bustling concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental a great choice for family trips.