Title: Main Street-Science World Station Accommodation - Find the 10 Best Hotels near Main Street-Science World Station, Vancouver | Book on Expedia.com [Downtown Vancouver Travel Guide](https://expedia.com/Vancouver-Downtown-Vancouver.dx6058432)[Car Rentals in Downtown Vancouver](https://expedia.com/Car-Rentals-In-Downtown-Vancouver.d6058432.Car-Rental-Guide)[Downtown Vancouver Vacation Packages](https://expedia.com/Downtown-Vancouver.d6058432.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=6215451&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 7 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=6215451&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=6215451&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=6215451&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Main Street-Science World Station hotels ![50-inch Smart TV with cable channels, streaming services](https://images.trvl-media.com/lodging/114000000/113090000/113080100/113080002/4b11554a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace Apartment | Terrace/patio](https://images.trvl-media.com/lodging/114000000/113090000/113080100/113080002/5fa4a293.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![One Bedroom Apartment | Living area | 50-inch Smart TV with cable channels, streaming services](https://images.trvl-media.com/lodging/114000000/113090000/113080100/113080002/4dbfeb32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113090000/113080100/113080002/bda165ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keefer House [](https://www.expedia.com/Vancouver-Hotels-Keefer-House.h113080002.Hotel-Information) Chinatown, 0.5 mi from Main Street-Science World Station 9.8/10 Exceptional (59 reviews) "Had a great stay! Good location, very clean and great communication from the staff. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jordyn $111 nightly $132 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Vancouver-Hotels-Keefer-House.h113080002.Hotel-Information) ![Family Apartment | Premium bedding, pillowtop beds, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/105000000/104440000/104438700/104438673/80aeb976.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Premium bedding, pillowtop beds, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/105000000/104440000/104438700/104438673/3fd04446.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/105000000/104440000/104438700/104438673/cc4f0357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio | Private kitchen | Fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/105000000/104440000/104438700/104438673/e15f4bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Smithe House [](https://www.expedia.com/Vancouver-Hotels-Smithe-House.h104438673.Hotel-Information) Yaletown, 0.8 mi from Main Street-Science World Station 9.8/10 Exceptional (368 reviews) "Excellent rooms and location. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Peter $190 nightly $227 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Vancouver-Hotels-Smithe-House.h104438673.Hotel-Information) ![Signature Suite, 1 Bedroom | Living area | 48-inch LED TV with cable channels, TV, iPod dock](https://images.trvl-media.com/lodging/2000000/1970000/1968700/1968637/20ebc156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1970000/1968700/1968637/c37b16ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1970000/1968700/1968637/76f5317a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1970000/1968700/1968637/40cefda9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### L'Hermitage Hotel [](https://www.expedia.com/Vancouver-Hotels-LHermitage-Hotel.h1968637.Hotel-Information) Downtown Vancouver, 0.9 mi from Main Street-Science World Station 9.8/10 Exceptional (1,002 reviews) "Amazing place to stay. Room was great and staff super friendly." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Robin $172 nightly $205 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Vancouver-Hotels-LHermitage-Hotel.h1968637.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/8000000/7840000/7834400/7834356/99f50b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/8000000/7840000/7834400/7834356/ef0b562b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7840000/7834400/7834356/56aa9234.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Quadruple Room, 2 Queen Beds | View from room](https://images.trvl-media.com/lodging/8000000/7840000/7834400/7834356/7cb9b067.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Blu Vancouver [](https://www.expedia.com/Vancouver-Hotels-Hotel-Blu-Vancouver.h7834356.Hotel-Information) Downtown Vancouver, 0.7 mi from Main Street-Science World Station 9.6/10 Exceptional (3,573 reviews) "Clean rooms, great staff and location !" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Vanessa $169 nightly $202 total Feb 9 - Feb 10 Total with taxes and fees [](https://www.expedia.com/Vancouver-Hotels-Hotel-Blu-Vancouver.h7834356.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3200/3107/5c0c0115.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3200/3107/6deab6f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3200/3107/f859990a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3200/3107/313736d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rosewood Hotel Georgia [](https://www.expedia.com/Vancouver-Hotels-Rosewood-Hotel-Georgia.h3107.Hotel-Information) Downtown Vancouver, 1.1 mi from Main Street-Science World Station 9.8/10 Exceptional (1,086 reviews) "Amazing hotel, beautiful staff " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Kimberleigh $362 nightly $432 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Vancouver-Hotels-Rosewood-Hotel-Georgia.h3107.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6500/6476/07ebcd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/6500/6476/0a143969.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with cable channels, TV, iPod dock](https://images.trvl-media.com/lodging/1000000/10000/6500/6476/b398f5a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/1000000/10000/6500/6476/3d5e5b55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wedgewood Hotel & Spa [](https://www.expedia.com/Vancouver-Hotels-Wedgewood-Hotel-Spa-Relais-Chateaux.h6476.Hotel-Information) Downtown Vancouver, 1.2 mi from Main Street-Science World Station 9.8/10 Exceptional (1,348 reviews) "Very hospitable, clean and location was great" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Nicole $220 nightly $262 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Vancouver-Hotels-Wedgewood-Hotel-Spa-Relais-Chateaux.h6476.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/23000000/22870000/22861900/22861813/c5eb8e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22870000/22861900/22861813/e2cfd400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive lounge](https://images.trvl-media.com/lodging/23000000/22870000/22861900/22861813/w1600h996x0y71-1fe10747.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Mediterranean cuisine ](https://images.trvl-media.com/lodging/23000000/22870000/22861900/22861813/e67a98dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EXchange Hotel Vancouver [](https://www.expedia.com/Vancouver-Hotels-EXchange-Hotel-Vancouver.h22861813.Hotel-Information) Downtown Vancouver, 1.1 mi from Main Street-Science World Station 9.6/10 Exceptional (3,128 reviews) "Great hotel, clean and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tharsana $155 nightly $184 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Vancouver-Hotels-EXchange-Hotel-Vancouver.h22861813.Hotel-Information) ![Room, 1 King Bed (Secret Garden) | Exterior](https://images.trvl-media.com/lodging/1000000/850000/849600/849562/7891c772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch LED TV with cable channels, TV, iPod dock](https://images.trvl-media.com/lodging/1000000/850000/849600/849562/655cdbe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite (OPUS) | Property amenity](https://images.trvl-media.com/lodging/1000000/850000/849600/849562/dd31d1a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/850000/849600/849562/86e3bc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OPUS Hotel Vancouver [](https://www.expedia.com/Vancouver-Hotels-OPUS-Hotel-Vancouver.h849562.Hotel-Information) Yaletown, 1 mi from Main Street-Science World Station 9.6/10 Exceptional (1,104 reviews) "The staff were amazing, beautiful boutique hotel. Location was excellent. We will definitely be staying there again!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Edward $169 nightly $202 total Feb 8 - Feb 9 Total with taxes and fees [](https://www.expedia.com/Vancouver-Hotels-OPUS-Hotel-Vancouver.h849562.Hotel-Information) ![55-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/1000000/30000/26900/26863/9c7dcdea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/30000/26900/26863/373a2c24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/30000/26900/26863/649be51a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26900/26863/ae01d135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Georgian Court Hotel, WorldHotels Elite [](https://www.expedia.com/Vancouver-Hotels-Georgian-Court-Hotel-BW-Premier-Collection.h26863.Hotel-Information) Downtown Vancouver, 0.7 mi from Main Street-Science World Station 9.4/10 Exceptional (3,838 reviews) "Easy to check in, great staff and clean rooms!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jodie $125 nightly $149 total Feb 9 - Feb 10 Total with taxes and fees [](https://www.expedia.com/Vancouver-Hotels-Georgian-Court-Hotel-BW-Premier-Collection.h26863.Hotel-Information) ![Luxury Penthouse, 2 Bedrooms, Kitchen, Partial Sea View (Halo) | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1760000/1759300/1759251/928897cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1760000/1759300/1759251/ec61a13e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Penthouse, 2 Bedrooms, Kitchen, Partial Sea View (Halo) | Living area | 42-inch LCD TV with cable channels, TV](https://images.trvl-media.com/lodging/2000000/1760000/1759300/1759251/8073679d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Terrace, Garden View | View from room](https://images.trvl-media.com/lodging/2000000/1760000/1759300/1759251/49a09b35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loden Hotel [](https://www.expedia.com/Vancouver-Hotels-Loden-Hotel.h1759251.Hotel-Information) Coal Harbour, 1.4 mi from Main Street-Science World Station 9.8/10 Exceptional (1,001 reviews) "Room was beautiful and staff were great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa $376 nightly $448 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Vancouver-Hotels-Loden-Hotel.h1759251.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22®ionId=6215451&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Main Street-Science World Station | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | | | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | --------------------------- | --------------------------- | ---- | --- | ------------ | ------------- | | | ![50-inch Smart TV with cable channels, streaming services](https://images.trvl-media.com/lodging/114000000/113090000/113080100/113080002/4b11554a.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Keefer House | 4.0 star property | 9.8Exceptional59 reviews | View | | | | | | | ![Family Apartment \| Premium bedding, pillowtop beds, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/105000000/104440000/104438700/104438673/80aeb976.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Smithe House | 4.0 star property | 9.8Exceptional368 reviews | View | | | | | | | ![Signature Suite, 1 Bedroom \| Living area | 48-inch LED TV with cable channels, TV, iPod dock](https://images.trvl-media.com/lodging/2000000/1970000/1968700/1968637/20ebc156.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)L'Hermitage Hotel | 4.0 star property | 9.8Exceptional1,002 reviews | View | | | | | | ![Front of property - evening/night](https://images.trvl-media.com/lodging/8000000/7840000/7834400/7834356/99f50b6b.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Blu Vancouver | 4.0 star property | 9.6Exceptional3,573 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3200/3107/5c0c0115.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Rosewood Hotel Georgia | 5.0 star property | 9.8Exceptional1,086 reviews | View | | | | | | ## Top Main Street-Science World Station Hotel Reviews ![River Rock Casino Resort](https://images.trvl-media.com/lodging/5000000/4820000/4810600/4810562/97784f46_y.jpg) ### River Rock Casino Resort 10/10 Excellent "Friendly staff, clean comfortable room." [](https://expedia.com/Vancouver-Hotels-River-Rock-Casino-Resort.h4810562.Hotel-Information) ![Century Plaza Hotel](https://images.trvl-media.com/lodging/1000000/20000/19300/19256/2b28e091_y.jpg) ### Century Plaza Hotel 10/10 Excellent "Clean room, friendly and courteous staff. " [](https://expedia.com/Vancouver-Hotels-Century-Plaza-Hotel-Spa.h19256.Hotel-Information) ![Sandman Hotel Vancouver Downtown](https://images.trvl-media.com/lodging/1000000/30000/21900/21807/7a45bf6e_y.jpg) ### Sandman Hotel Vancouver Downtown 10/10 Excellent "Location " [](https://expedia.com/Vancouver-Hotels-Sandman-Hotel-Vancouver-Downtown.h21807.Hotel-Information) ![Atrium Hotel Vancouver](https://images.trvl-media.com/lodging/1000000/10000/7600/7557/d20fbd36_y.jpg) ### Atrium Hotel Vancouver 10/10 Excellent "Very good for the service the rooms were very clean" [](https://expedia.com/Vancouver-Hotels-Atrium-Inn-Vancouver.h7557.Hotel-Information) ![Radisson Blu Vancouver Airport Hotel & Marina](https://images.trvl-media.com/lodging/1000000/30000/28000/28000/3828c456_y.jpg) ### Radisson Blu Vancouver Airport Hotel & Marina 10/10 Excellent "Good service " [](https://expedia.com/Vancouver-Hotels-Pacific-Gateway-Hotel.h28000.Hotel-Information) ![Hyatt Regency Vancouver](https://images.trvl-media.com/lodging/1000000/10000/3300/3203/0c7c549e_y.jpg) ### Hyatt Regency Vancouver 10/10 Excellent "The room was spotless and the young lady that checked us in was wonderful. It was my birthday and they hotel had a dessert waiting for me after our spa treatment. Just wish they would keep the hot tub open until 11pm. 10-11pm for adults only would be great. " [](https://expedia.com/Vancouver-Hotels-Hyatt-Regency-Vancouver.h3203.Hotel-Information) ![The Burrard](https://images.trvl-media.com/lodging/4000000/3680000/3674200/3674197/2cd7aa46_y.jpg) ### The Burrard 10/10 Excellent "Amazing!" [](https://expedia.com/Vancouver-Hotels-The-Burrard.h3674197.Hotel-Information) ![Sheraton Vancouver Wall Centre](https://images.trvl-media.com/lodging/1000000/20000/11700/11699/2b9f1e3e_y.jpg) ### Sheraton Vancouver Wall Centre 10/10 Excellent "Modern and clean room, great views, great amenities. I had a short stay but very comfortable and pleasant." [](https://expedia.com/Vancouver-Hotels-Sheraton-Vancouver-Wall-Centre.h11699.Hotel-Information) ![Pinnacle Hotel Harbourfront](https://images.trvl-media.com/lodging/1000000/20000/13400/13323/9a046af9_y.jpg) ### Pinnacle Hotel Harbourfront 10/10 Excellent "Great stay" [](https://expedia.com/Vancouver-Hotels-Pinnacle-Hotel-Harbourfront.h13323.Hotel-Information) ## Frequently asked questions ### What's the area like around Main Street-Science World Station? ### What's the best place to stay near Main Street-Science World Station? ### How many hotels are there near Main Street-Science World Station? ### What can I see and do near Main Street-Science World Station? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Vancouver Hotels ](https://www.expedia.com/Vancouver-Hotels.d178315.Travel-Guide-Hotels) - [Hotels near Downtown Vancouver ](https://www.expedia.com/Downtown-Vancouver-Vancouver-Hotels.0-n6058432-0.Travel-Guide-Filter-Hotels) - 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