McClure Vacation Rentals

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In four months
Apr 10 - Apr 12

Our top choices for McClure vacation rentals

Exterior
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Cabin in Anna

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
10.0 out of 10, Exceptional, (403)
"Very clean, courteus staff. Beautiful area and quiet. Very relaxing."
United States
Tommy
$191 nightly
The price is $202
Dec 18 - Dec 19
Total with taxes and fees
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Exterior
Charming cottage overlooking Lake Acre

Cabin in Dongola

Charming cottage overlooking Lake Acre
10.0 out of 10, Exceptional, (101)
"Location was great, everything was great for what we were there for. Already booked again for November. "
United States
carlton h.
$265 nightly
The price is $281
Dec 21 - Dec 22
Total with taxes and fees
Charming cottage overlooking Lake Acre
Dining
Cozy cabins on beautiful Horseshoe Lake

Cabin in Olive Branch

Cozy cabins on beautiful Horseshoe Lake
9.8 out of 10, Exceptional, (35)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
$133 nightly
The price is $140
Dec 22 - Dec 23
Total with taxes and fees
Cozy cabins on beautiful Horseshoe Lake
Private kitchen
Cozy and Updated Farmhouse with King Suite

Vacation Home in Anna

Cozy and Updated Farmhouse with King Suite
2.0 star property
$139 nightly
The price is $148
Dec 16 - Dec 17
Total with taxes and fees
Cozy and Updated Farmhouse with King Suite
Fridge, microwave, oven, stovetop
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Apartment in Cape Girardeau

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
9.4 out of 10, Exceptional, (45)
"This place is AWESOME! It's clean, artsy, fun, and if we ever have a chance, we will certainly return!"
United States
Jordan S.
$132 nightly
The price is $138
Dec 16 - Dec 17
Total with taxes and fees
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Interior
The Rested Duck Mallard Room

Cabin in Olive Branch

The Rested Duck Mallard Room
9.2 out of 10, Wonderful, (25)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
$133 nightly
The price is $140
Dec 21 - Dec 22
Total with taxes and fees
The Rested Duck Mallard Room
Terrace/patio
Contemporary Glamping with Native American Appeal

Cabin in Anna

Contemporary Glamping with Native American Appeal
9.8 out of 10, Exceptional, (155)
"Our 2nd time staying here and it was perfect"
United States
machelle p.
$282 nightly
The price is $284
Dec 17 - Dec 18
Total with taxes and fees
Contemporary Glamping with Native American Appeal
Interior
Little Blue Cottage on Spanish

Vacation Home in Cape Girardeau

Little Blue Cottage on Spanish
8.6 out of 10, Excellent, (48)
"I would definitely stay here again!"
United States
Bonita
$101 nightly
The price is $101
Dec 16 - Dec 17
Total with taxes and fees
Little Blue Cottage on Spanish
Exterior
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Vacation Home in Cape Girardeau

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
8.6 out of 10, Excellent, (36)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
United States
Emily D.
$206 nightly
The price is $214
Dec 16 - Dec 17
Total with taxes and fees
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Terrace/patio
The Twisted Sassafras Treehouse

Cabin in Cape Girardeau

The Twisted Sassafras Treehouse
10.0 out of 10, Exceptional, (27)
"The place was awesome very clean the host was very accommodating. Nice a quiet for a relaxing stay highly recommend "
United States
Gary C.
$289 nightly
The price is $301
Dec 16 - Dec 17
Total with taxes and fees
The Twisted Sassafras Treehouse
Fridge, microwave, oven, stovetop
Villa B offers peace and quiet with beautiful views of the countryside.

Apartment in Jackson

Villa B offers peace and quiet with beautiful views of the countryside.
10.0 out of 10, Exceptional, (11)
"Our stay was amazing. Everything was so clean organized, and anything you would possibly need was in the room. We will definitely be staying there again when in the area!!"
United States
Karen P.
$172 nightly
The price is $185
Jan 2 - Jan 3, 2026
Total with taxes and fees
Villa B offers peace and quiet with beautiful views of the countryside.
Interior
Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Vacation Home in Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro
10.0 out of 10, Exceptional, (4)
"great place. wonderful host."
United States
Carla m.
$237 nightly
The price is $252
Dec 16 - Dec 17
Total with taxes and fees
Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Fridge, microwave, oven, stovetop
Serenity South -- Gardens, River-Views, and Refreshing Space

Vacation Home in Cape Girardeau

Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (148)
"Such a great place and location"
United States
Tracy H.
$229 nightly
The price is $245
Dec 16 - Dec 17
Total with taxes and fees
Serenity South -- Gardens, River-Views, and Refreshing Space
Exterior detail
Gorgeous 1856 Log Cabin, Completely Renovated

Cabin in Jackson

Gorgeous 1856 Log Cabin, Completely Renovated
10.0 out of 10, Exceptional, (3)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
$310 nightly
The price is $310
Dec 16 - Dec 17
Total with taxes and fees
Gorgeous 1856 Log Cabin, Completely Renovated
TV, fireplace
Contemporary Glamping with Native American Appeal!

Cabin in Anna

Contemporary Glamping with Native American Appeal!
10.0 out of 10, Exceptional, (102)
"We loved our stay! The accommodations were clean and comfortable. The cabin atmosphere very was relaxing. We will be back. "
United States
Beth C.
Contemporary Glamping with Native American Appeal!
Fridge, microwave, oven, stovetop
Relax in the country at Countryside Villas! - Villa A

Apartment in Jackson

Relax in the country at Countryside Villas! - Villa A
10.0 out of 10, Exceptional, (33)
"Great place to stay, felt like home away from home. "
United States
Brittany
$172 nightly
The price is $185
Dec 17 - Dec 18
Total with taxes and fees
Relax in the country at Countryside Villas! - Villa A
TV, fireplace
The Cottage, Rusted Route Farms

Mobile Home in Jackson

The Cottage, Rusted Route Farms
10.0 out of 10, Exceptional, (2)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
$195 nightly
The price is $195
Dec 22 - Dec 23
Total with taxes and fees
The Cottage, Rusted Route Farms
Property grounds
Historic Farm Cottage on 800-Acre Orchard

Vacation Home in Alto Pass

Historic Farm Cottage on 800-Acre Orchard
9.8 out of 10, Exceptional, (8)
"Awesome"
United States
Luke K.
$186 nightly
The price is $205
Jan 5 - Jan 6, 2026
Total with taxes and fees
Historic Farm Cottage on 800-Acre Orchard
Exterior
Magical Victorian near hiking / wine trail

Vacation Home in Anna

Magical Victorian near hiking / wine trail
10.0 out of 10, Exceptional, (4)
"The house was beautiful! We were in awe of the decor and layout. This is a must-stay if you are in southern Illinois!"
United States
Lori C.
$348 nightly
The price is $393
Dec 16 - Dec 17
Total with taxes and fees
Magical Victorian near hiking / wine trail
Exterior
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Vacation Home in Cape Girardeau

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
9.6 out of 10, Exceptional, (7)
"Nice place, great times"
United States
Jace W.
$422 nightly
The price is $438
Dec 16 - Dec 17
Total with taxes and fees
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top McClure Hotel Reviews

The Riverview

The Riverview

10/10 Excellent
"Didn’t eat breakfast "
Michael 1-night trip
Posted 4 days ago
The Riverview

Find out more about McClure

Everything you need to know about McClure vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the McClure vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect McClure vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

McClure vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in McClure. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit McClure in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $101 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on McClure rentals

At Expedia, we put the best McClure vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top McClure rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream McClure vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around McClure. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in McClure?

Yes, we have vacation rentals close to top sights in McClure, or you can go with a more remote option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals in McClure?

* On the Wine Trail * Hot Tub * Wi-Fi *: You might want to consider this vacation home rental near McClure, which is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What can I see and do in McClure?

Explore the area and family-friendly sights such as Cape Splash Family Aquatic Center, or get out into nature at a spot like Cape Rock Park. In the larger area, you’ll find Devil's Island Wildlife Management Area and Isle Casino Cape Girardeau.

What are vacation rentals like in McClure?

Vacation rentals are privately owned accommodations you can stay in for several days or more in McClure. Vacation rentals offer extras like laundry facilities and kitchens so you'll feel right at home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy front desks while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive choice for family gatherings.