Pine Island Vacation Rentals

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Our top choices for Pine Island vacation rentals

Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!

Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!
Rochester
9.6 out of 10, Exceptional, (23)
"Great location "
United States
Peary S.
$152 nightly
The price is $175
Dec 14 - Dec 15
Total with taxes and fees
Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!

Apple Blossom Cottage // 2 Miles from Downtown ~ 10 Min to Mayo

Apple Blossom Cottage // 2 Miles from Downtown ~ 10 Min to Mayo
Rochester
9.8 out of 10, Exceptional, (11)
"Very comfortable home away from home"
United States
ROBERT B.
$216 nightly
The price is $248
Dec 19 - Dec 20
Total with taxes and fees
Apple Blossom Cottage // 2 Miles from Downtown ~ 10 Min to Mayo

Discounted Charming 2-bedroom house in Rochester

Discounted Charming 2-bedroom house in Rochester
East Side Pioneers
8.6 out of 10, Excellent, (11)
"Great stay for a quick stop in Rochester. Clean, quiet neighborhood."
United States
Jill S.
$168 nightly
The price is $193
Dec 14 - Dec 15
Total with taxes and fees
Discounted Charming 2-bedroom house in Rochester

Charming 2-bedroom apartment in delightful Rochester with WiFi, AC

Charming 2-bedroom apartment in delightful Rochester with WiFi, AC
Meadow Park
10.0 out of 10, Exceptional, (1)
"Quiet, clean and in a friendly neighborhood. Staying there took some of the stress out of my Mayo Clinic visits. I always worry about my follow-up visits, but a good quiet place to stay helps me let that go."
United States
Maria L E.
$140 nightly
The price is $201
Dec 14 - Dec 15
Total with taxes and fees
Charming 2-bedroom apartment in delightful Rochester with WiFi, AC

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
East Side Pioneers
9.0 out of 10, Wonderful, (19)
"Nicely updated, very clean. Great location. They do allow pets, however it does not have a fenced yard. It is a duplex."
United States
Chris P.
$180 nightly
The price is $208
Dec 14 - Dec 15
Total with taxes and fees
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

The Berkman

The Berkman
3.0 star property
Folwell
9.6 out of 10, Exceptional, (370)
"Staff was great, as was the room."
United States
Scott
$157 nightly
The price is $180
Dec 24 - Dec 25
Total with taxes and fees
The Berkman

The Cozy Hideaway - 5-Minute Drive to Mayo Clinic

The Cozy Hideaway - 5-Minute Drive to Mayo Clinic
Northrup
9.0 out of 10, Wonderful, (4)
"Perfect place to stay if needing to be close to Mayo. "
United States
Andrea S.
$209 nightly
The price is $241
Dec 14 - Dec 15
Total with taxes and fees
The Cozy Hideaway - 5-Minute Drive to Mayo Clinic

Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!

Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!
Rochester
10.0 out of 10, Exceptional, (8)
"It was amazing stay, it was very comfy, welcoming and definitely something we would book again!!"
United States
Jessica Z.
$219 nightly
The price is $252
Dec 19 - Dec 20
Total with taxes and fees
Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!

1742 Uptown // Stylish w/Updates, 3BD, Walk to Mayo, Pet Friendly

1742 Uptown // Stylish w/Updates, 3BD, Walk to Mayo, Pet Friendly
Rochester
10.0 out of 10, Exceptional, (21)
"Great communication, clean accommodations, convenient to Mayo Clinic and very comfortable bed."
United States
Karen R.
$335 nightly
The price is $386
Dec 14 - Dec 15
Total with taxes and fees
1742 Uptown // Stylish w/Updates, 3BD, Walk to Mayo, Pet Friendly

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (167)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
$148 nightly
The price is $170
Dec 27 - Dec 28
Total with taxes and fees
Broadway Plaza, Trademark Collection by Wyndham

4 blks St Marys Main fl beds/bath CoveredByFaith

4 blks St Marys Main fl beds/bath CoveredByFaith
Kutzky Park
9.8 out of 10, Exceptional, (59)
"We enjoyed our stay."
United States
Joseph V.
$209 nightly
The price is $241
Dec 14 - Dec 15
Total with taxes and fees
4 blks St Marys Main fl beds/bath CoveredByFaith

Close to Mayo & Shops, 1 step entry CoveredByFaith

Close to Mayo & Shops, 1 step entry CoveredByFaith
Rochester
9.8 out of 10, Exceptional, (12)
"Peaceful and relaxing, perfect vacation home. Excellent hosts!!!"
United States
Ellaina M.
$230 nightly
The price is $265
Dec 16 - Dec 17
Total with taxes and fees
Close to Mayo & Shops, 1 step entry CoveredByFaith

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic
Slatterly Park
10.0 out of 10, Exceptional, (17)
"We had a wonderful time visiting Minnesota for our first time! We would most definitely stay here again. Had everything we needed and was so great for our dogs to tag along too! Would 100% recommend staying here. "
United States
Hannah C.
$199 nightly
The price is $229
Dec 22 - Dec 23
Total with taxes and fees
The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

Lux 3 BR mins to Mayo & Dwtwn I Charming Haven

Lux 3 BR mins to Mayo & Dwtwn I Charming Haven
2.0 star property
Rochester
10.0 out of 10, Exceptional, (6)
"This property had everything we needed. Super cute and simple decor, comfortable beds and clean. We would stay here again!! "
United States
Anonymous traveler
$384 nightly
The price is $440
Dec 16 - Dec 17
Total with taxes and fees
Lux 3 BR mins to Mayo & Dwtwn I Charming Haven

Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers!

Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers!
Rochester
10.0 out of 10, Exceptional, (3)
"Very nice and convenient stay. Everything we needed and extremely well maintained room and kitchen. Loved it and the responsiveness out our hosts!"
United States
Rick H.
$128 nightly
The price is $147
Jan 4 - Jan 5, 2026
Total with taxes and fees
Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers!

King Suite Close to Mayo Clinic! Free Breakfast. Pool & Hot Tub.

King Suite Close to Mayo Clinic! Free Breakfast. Pool & Hot Tub.
Rochester
10.0 out of 10, Exceptional, (1)
"Good hotel with plenty of space to spread out. Great location with coffee and dining across the street. Easy to find and easy access to highways. Will stay here again!"
United States
Michael F.
$130 nightly
The price is $149
Jan 4 - Jan 5, 2026
Total with taxes and fees
King Suite Close to Mayo Clinic! Free Breakfast. Pool & Hot Tub.

The Color House // 2 Bed, 2 Ba, 1 mi to Mayo Clinic, No Stairs to Entry

The Color House // 2 Bed, 2 Ba, 1 mi to Mayo Clinic, No Stairs to Entry
East Side Pioneers
9.4 out of 10, Exceptional, (13)
"Great place!"
United States
Jeremiah E.
$239 nightly
The price is $276
Dec 21 - Dec 22
Total with taxes and fees
The Color House // 2 Bed, 2 Ba, 1 mi to Mayo Clinic, No Stairs to Entry

Lovely Two Bedroom Apartment Off Bike Trail

Lovely Two Bedroom Apartment Off Bike Trail
Cannon Falls
9.8 out of 10, Exceptional, (27)
"We were in town for a horse show at the arena in town and this is an excellent place to stay. Close to everything and Jane is so nice. "
United States
Erin J.
$160 nightly
The price is $172
Dec 14 - Dec 15
Total with taxes and fees
Lovely Two Bedroom Apartment Off Bike Trail

3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith

3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith
Folwell
9.6 out of 10, Exceptional, (24)
"Very clean and ready for us to stay when we arrived."
United States
David L.
$199 nightly
The price is $229
Dec 14 - Dec 15
Total with taxes and fees
3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith

3 blks to St. Marys Pet Friendly CoveredByFaith

3 blks to St. Marys Pet Friendly CoveredByFaith
Folwell
9.2 out of 10, Wonderful, (10)
"It was everything we needed for our short stay in Rochester. Place was as described. "
United States
Joseph N.
$198 nightly
The price is $228
Dec 14 - Dec 15
Total with taxes and fees
3 blks to St. Marys Pet Friendly CoveredByFaith
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pine Island Hotel Reviews

Find out more about Pine Island

Everything you need to know about Pine Island vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Pine Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Pine Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Pine Island vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Pine Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Pine Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $138 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Pine Island rentals

At Expedia, we put the best Pine Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Pine Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Pine Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Pine Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Pine Island?

Yes, there are vacation rentals near the most popular attractions in Pine Island, or you can select a more secluded option if you'd like a relaxing place to stay.

What are some of the best vacation rentals in Pine Island?

SUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO: This vacation home rental near Pine Island offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings.

What can I see and do in Pine Island?

While exploring the area, visit family-friendly sights like Minnesota Children's Museum, or get outside and enjoy nature at Zumbro Lake. In the larger area, you’ll find Assisi Heights and Rochester Recreation Center.

What are vacation rentals like in Pine Island?

Vacation rentals are private accommodations you can reserve for several days or more in Pine Island. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive choice for a small group gathering.