Title: Pine Island Vacation Rentals from $120: Search Short-Term Rentals | Expedia.com

[Hotels in Pine Island](https://expedia.com/Pine-Island-Hotels.d553248635975874860.Travel-Guide-Hotels)[Car Rentals in Pine Island](https://expedia.com/Car-Rentals-In-Pine-Island.d553248635975874860.Car-Rental-Guide)[Pine Island Vacation Packages](https://expedia.com/Pine-Island.d553248635975874860.Destination-Travel-Guides)

![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=553248635975874860&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 15 - May 17](https://www.expedia.com/Hotel-Search?regionId=553248635975874860&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 12 - Jun 14](https://www.expedia.com/Hotel-Search?regionId=553248635975874860&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 10 - Jul 12](https://www.expedia.com/Hotel-Search?regionId=553248635975874860&startDate=2026-07-10&endDate=2026-07-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Pine Island vacation rentals

![Exterior](https://images.trvl-media.com/lodging/101000000/100200000/100194400/100194373/dc05b783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100200000/100194400/100194373/c7575fb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/101000000/100200000/100194400/100194373/a6e50dd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/101000000/100200000/100194400/100194373/a6c285de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2 bedroom apartment in downtown Zumbrota. Sleeps 4-6.

[](https://www.expedia.com/Zumbrota-Hotels-2-Bedroom-Apartment-In-Downtown-Zumbrota-Sleeps-4-6.h100194373.Hotel-Information)

Zumbrota

10/10

Exceptional

(63 reviews)

"This hostess thought about everything and its the only placed to stay that is nice within 30 minutes of where we were and affordable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janelle

$119 nightly

$128 total

Apr 3 - Apr 4

Total with taxes and fees

[](https://www.expedia.com/Zumbrota-Hotels-2-Bedroom-Apartment-In-Downtown-Zumbrota-Sleeps-4-6.h100194373.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/52000000/51270000/51267300/51267208/90-3e521435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/52000000/51270000/51267300/51267208/90-3a8a456d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/52000000/51270000/51267300/51267208/18c8f73f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/52000000/51270000/51267300/51267208/0fc84c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Magical Nest Hideaway

[](https://www.expedia.com/Rochester-Hotels-Magical-Nest-Hideaway.h51267208.Hotel-Information)

Rochester

10/10

Exceptional

(141 reviews)

"Great place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew S.

$104 nightly

$120 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Magical-Nest-Hideaway.h51267208.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/5776b64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/50c22b07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Billiards](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/6b44b2f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/9c4ccb32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Berkman

[](https://www.expedia.com/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information)

Folwell

9.6/10

Exceptional

(392 reviews)

"Everything was excellent, second time staying there. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carolyn

$116 nightly

$133 total

Mar 21 - Mar 22

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Berkman-Hotel.h46291477.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/113000000/112840000/112838900/112838810/db2bcbab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/113000000/112840000/112838900/112838810/b2be6c45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112840000/112838900/112838810/8229b3dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/113000000/112840000/112838900/112838810/f49e01b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

[](https://www.expedia.com/Rochester-Hotels-Discounted-Charming-2-Bedroom-House-In-Rochester.h112838810.Hotel-Information)

East Side Pioneers

8.8/10

Excellent

(13 reviews)

"Great stay for a quick stop in Rochester. Clean, quiet neighborhood."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jill S.

$168 nightly

$193 total

Mar 25 - Mar 26

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Discounted-Charming-2-Bedroom-House-In-Rochester.h112838810.Hotel-Information)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/120000000/119760000/119751900/119751899/bde39aeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/120000000/119760000/119751900/119751899/1869e1d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/120000000/119760000/119751900/119751899/4a112a03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119760000/119751900/119751899/11aaf550.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

[](https://www.expedia.com/Rochester-Hotels-Meet-Don-A-Modern.h119751899.Hotel-Information)

Slatterly Park

10/10

Exceptional

(21 reviews)

"This is a great property! Highly recommend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anne G.

$204 nightly

$234 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Meet-Don-A-Modern.h119751899.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499051/aa49983d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499051/5086ed6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, DVD player, offices](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499051/1c72d53e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499051/83319de8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### King Suite Close to Mayo Clinic! Free Breakfast. Pool & Hot Tub.

[](https://www.expedia.com/Rochester-Hotels-King-Suite-Close-To-Mayo-Clinic-Free-Breakfast-Pool-Hot-Tub.h56499051.Hotel-Information)

Rochester

10/10

Exceptional

(1 review)

"Good hotel with plenty of space to spread out. Great location with coffee and dining across the street. Easy to find and easy access to highways. Will stay here again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael F.

$136 nightly

$156 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-King-Suite-Close-To-Mayo-Clinic-Free-Breakfast-Pool-Hot-Tub.h56499051.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/10e83a4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/d4ef1ad3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/5ce804eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/63c8ec1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!

[](https://www.expedia.com/Rochester-Hotels-2-Bedroom-Oasis-5-Minutes-To-Mayo-Clinic.h101428059.Hotel-Information)

Rochester

9.6/10

Exceptional

(27 reviews)

"This was a very clean and cozy property."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Angela O.

$186 nightly

$214 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-2-Bedroom-Oasis-5-Minutes-To-Mayo-Clinic.h101428059.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/c10ebe66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/18f935fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/62dcfb31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/2a592498.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!

[](https://www.expedia.com/Rochester-Hotels-5-Star-Restful-Haven-5-Minutes-To-Mayo-Clinic.h101161628.Hotel-Information)

Rochester

10/10

Exceptional

(9 reviews)

"It was amazing stay, it was very comfy, welcoming and definitely something we would book again!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jessica Z.

$256 nightly

$294 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-5-Star-Restful-Haven-5-Minutes-To-Mayo-Clinic.h101161628.Hotel-Information)

![Smart TV, books](https://images.trvl-media.com/lodging/72000000/71370000/71363500/71363416/6246ff2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/72000000/71370000/71363500/71363416/9c7af335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/72000000/71370000/71363500/71363416/6c81e0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, travel crib, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71370000/71363500/71363416/3effdd9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Little House // Stylish & Cozy \~ 2 mi from Mayo Clinic

[](https://www.expedia.com/Rochester-Hotels-Stylish-Cozy-2-Mi-From-Mayo-Clinic.h71363416.Hotel-Information)

Slatterly Park

10/10

Exceptional

(21 reviews)

"I love staying in their properties. I always know I am going to be comfortable and have a great stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carissa W.

$192 nightly

$221 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Stylish-Cozy-2-Mi-From-Mayo-Clinic.h71363416.Hotel-Information)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/94000000/93800000/93793600/93793571/a0150ca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/94000000/93800000/93793600/93793571/59ed3cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93800000/93793600/93793571/551ab46d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/94000000/93800000/93793600/93793571/1f961c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

[](https://www.expedia.com/Rochester-Hotels-Discounted-Oasis-5-Star-3-Bedroom-Showstopping-Duplex-4-Minutes-To-Mayo-Clinic.h93793571.Hotel-Information)

East Side Pioneers

8.8/10

Excellent

(28 reviews)

"We only needed the space while we were attending family in the hospital. The house met our needs and gave us privacy."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michelle B.

$197 nightly

$227 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Discounted-Oasis-5-Star-3-Bedroom-Showstopping-Duplex-4-Minutes-To-Mayo-Clinic.h93793571.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/13771477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/364d4839.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/f6e66ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, DVD player, offices](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/a2350e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers!

[](https://www.expedia.com/Rochester-Hotels-Studio-Suite-Free-Breakfast-Shared-Pool-Hot-Tub-Great-For-Business-Travelers.h56499019.Hotel-Information)

Rochester

8.6/10

Excellent

(4 reviews)

"Very nice and convenient stay. Everything we needed and extremely well maintained room and kitchen. Loved it and the responsiveness out our hosts!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rick H.

$144 nightly

$166 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Studio-Suite-Free-Breakfast-Shared-Pool-Hot-Tub-Great-For-Business-Travelers.h56499019.Hotel-Information)

![Smart TV, books](https://images.trvl-media.com/lodging/119000000/118970000/118966800/118966768/d46138d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118970000/118966800/118966768/40c65c2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/119000000/118970000/118966800/118966768/f588a75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/119000000/118970000/118966800/118966768/ac92f8ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

[](https://www.expedia.com/Rochester-Hotels-Meet-Bev.h118966768.Hotel-Information)

Washington

9.8/10

Exceptional

(24 reviews)

"Beautiful and CLEAN, convenient location. Will definitely stay again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Melissa W.

$173 nightly

$199 total

Mar 27 - Mar 28

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Meet-Bev.h118966768.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91500000/91490400/91490311/ed6ff145.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, DVD player, books, video library](https://images.trvl-media.com/lodging/92000000/91500000/91490400/91490311/ddf9e4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/92000000/91500000/91490400/91490311/f24acc38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/92000000/91500000/91490400/91490311/00a5a3ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2 Blks St Marys Main Fl Beds Bath CoveredByFaith

[](https://www.expedia.com/Rochester-Hotels-2-Blks-St-Marys-Main-Fl-Beds-Bath-Covered-By-Faith.h91490311.Hotel-Information)

Kutzky Park

10/10

Exceptional

(101 reviews)

"Easy check in and host was very helpful "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joshua M.

$252 nightly

$291 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-2-Blks-St-Marys-Main-Fl-Beds-Bath-Covered-By-Faith.h91490311.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83550000/83544300/83544246/6d7da33d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/84000000/83550000/83544300/83544246/41531a0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/84000000/83550000/83544300/83544246/fa74fd9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/84000000/83550000/83544300/83544246/317098ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cheshire House // Family Home, Fenced Yard, Pet Friendly, 2 mi from Mayo Clinic

[](https://www.expedia.com/Rochester-Hotels-Vrbo-Property.h83544246.Hotel-Information)

Rochester

10/10

Exceptional

(41 reviews)

"Great place to stay. Loved the fenced in yard for our dogs."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tara C.

$345 nightly

$397 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Vrbo-Property.h83544246.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/116000000/115540000/115537100/115537064/a164ebdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/116000000/115540000/115537100/115537064/840fddd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115540000/115537100/115537064/ba1a2203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/116000000/115540000/115537100/115537064/5414d2c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

[](https://www.expedia.com/Rochester-Hotels-Quiet-3-BDR-Home-Private-Sauna-Skyline-View-Close-To-Downtown-Mayo-Clinic.h115537064.Hotel-Information)

Rochester

10/10

Exceptional

(2 reviews)

"This was a fantastic experience, far better than anticipated! Only a couple of comments: this high tech house was a little over the head of my crew and a guidebook to show us how to use all those remotes would have been most welcome. And one of my folks was looking for a can opener… We had a lovely time and the next convention we have in Rochester I will book here again without hesitation! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Patricia B.

$406 nightly

$467 total

Mar 21 - Mar 22

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Quiet-3-BDR-Home-Private-Sauna-Skyline-View-Close-To-Downtown-Mayo-Clinic.h115537064.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/108000000/107910000/107903000/107902961/6c0e8062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/108000000/107910000/107903000/107902961/w1422h960x18y0-349de2b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/108000000/107910000/107903000/107902961/6299361d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/108000000/107910000/107903000/107902961/84b32a8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lux 3 BR mins to Mayo & Dwtwn I Charming Haven

[](https://www.expedia.com/Rochester-Hotels-Lux-3-BR-Mins-To-Mayo-Dwtwn-I-Charming-Haven.h107902961.Hotel-Information)

Rochester

10/10

Exceptional

(6 reviews)

"This property had everything we needed. Super cute and simple decor, comfortable beds and clean. We would stay here again!! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveler

$385 nightly

$441 total

Mar 21 - Mar 22

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Lux-3-BR-Mins-To-Mayo-Dwtwn-I-Charming-Haven.h107902961.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/101000000/100770000/100765800/100765738/7d5fbf59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100770000/100765800/100765738/8b90b0b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100770000/100765800/100765738/49d88a4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/101000000/100770000/100765800/100765738/2c88c11c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hart House // One Bed, 1 Ba, St Mary's Mayo Clinic from the Front Porch

[](https://www.expedia.com/Rochester-Hotels-Hart-House-One-Bed.h100765738.Hotel-Information)

Kutzky Park

10/10

Exceptional

(4 reviews)

"Fun neighborhood good bars and restaurants "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David M.

[](https://www.expedia.com/Rochester-Hotels-Hart-House-One-Bed.h100765738.Hotel-Information)

![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/116000000/115290000/115288200/115288129/bc2bfa15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/116000000/115290000/115288200/115288129/b11e3c72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/116000000/115290000/115288200/115288129/a537e54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/116000000/115290000/115288200/115288129/2d12ace9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.

[](https://www.expedia.com/Rochester-Hotels-Lux-3BR-Cozy-Nook-I-Mins-To-Mayo-Dwtwn-I-Pets.h115288129.Hotel-Information)

Rochester

9.8/10

Exceptional

(7 reviews)

"Nice place to stay, close to all the activities we wanted to do."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly K.

$395 nightly

$452 total

Mar 21 - Mar 22

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-Lux-3BR-Cozy-Nook-I-Mins-To-Mayo-Dwtwn-I-Pets.h115288129.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/103000000/102820000/102818100/102818074/79facf0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, travel crib, free WiFi](https://images.trvl-media.com/lodging/103000000/102820000/102818100/102818074/1686d319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102820000/102818100/102818074/f67ae586.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102820000/102818100/102818074/5a8adcc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Color House // 2 Bed, 2 Ba, 1 mi to Mayo Clinic, No Stairs to Entry

[](https://www.expedia.com/Rochester-Hotels-The-Color-House-2-Bed.h102818074.Hotel-Information)

East Side Pioneers

9.0/10

Wonderful

(14 reviews)

"Great place!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeremiah E.

$226 nightly

$260 total

Mar 23 - Mar 24

Total with taxes and fees

[](https://www.expedia.com/Rochester-Hotels-The-Color-House-2-Bed.h102818074.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Find vacation rentals that suit your style

Private vacation homes

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Condos

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Cottages

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Apartments

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Cabins

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## Top Pine Island Hotel Reviews

![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/41a1c74b_y.jpg)

### Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"Rooms are a little dated "

[](https://expedia.com/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information)

![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/edb11216_y.jpg)

### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good

"Clean rooms, night staff not in best mood. Restaurant is a 10/10 Old rooms. Need updating. Although beds comfortable "

[](https://expedia.com/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information)

![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bba1b373_y.jpg)

### Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Perfect downtown location walking distance (skyway) to civic center"

[](https://expedia.com/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information)

![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/1062bbaa_y.jpg)

### Kahler Grand Hotel

8/10 Good

"yes"

[](https://expedia.com/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information)

![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/c73455d9_y.jpg)

### Hampton Inn Rochester-South

10/10 Excellent

"Room was small but everything worked as it should and it was nice to have a smart tv. The breakfast was delicious! Very well stocked and good options. The staff were quick to get us into a room on arrival at 11am during the snowstorm. Also the pool and hot tub were clean and not crowded, plus open 24hrs was nice!"

[](https://expedia.com/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information)

![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg)

### EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Hotel was clean staff bery friendly "

[](https://expedia.com/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information)

![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg)

### AmericInn by Wyndham Rochester Near Mayo Clinic

6/10 Okay

"Bed was very uncomfortable and not a lotion bottle to be found. Restaurant was very good. "

[](https://expedia.com/Rochester-Hotels-AmericInn-By-Wyndham-Rochester-Near-Mayo-Clinic.h8008.Hotel-Information)

![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3837h2560x3y0-1092e125_y.jpg)

### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

8/10 Good

"Room is very clean. Hallways needed to be vacuumed but could have been due to weather. Polite staff!"

[](https://expedia.com/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information)

![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/abb2c83e_y.jpg)

### Brentwood Inn & Suites

4/10 Poor

"Needs renovating badly. Elevators are ridiculously slow as well. Rooms are poorly layed out. Mattresses are horrible. The positives are that the rooms are fairly quiet, and reasonably clean. "

[](https://expedia.com/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information)

## Find out more about Pine Island

**Everything you need to know about Pine Island vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Pine Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Pine Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Pine Island vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Pine Island. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Pine Island in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $120 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Pine Island rentals**

At Expedia, we put the best Pine Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Pine Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Pine Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Pine Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

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- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in Pine Island ](https://expedia.com/Pine-Island-Private-Vacation-Homes.d553248635975874860-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Apartments in Pine Island ](https://expedia.com/Pine-Island-Apartments.d553248635975874860-aaApartments.Travel-Guide-Accommodation)
- [Condo Rentals in Pine Island ](https://expedia.com/Pine-Island-Condos.d553248635975874860-aaCondos.Travel-Guide-Accommodation)
- [Cottages in Pine Island ](https://expedia.com/Pine-Island-Cottages.d553248635975874860-aaCottages.Travel-Guide-Accommodation)
- [Motels in Pine Island ](https://expedia.com/Pine-Island-Motels.d553248635975874860-aaMotels.Travel-Guide-Accommodation)
- [Aparthotels in Pine Island ](https://expedia.com/Pine-Island-Apart-Hotels.d553248635975874860-aaApartHotels.Travel-Guide-Accommodation)
- [Cabin Rentals in Pine Island ](https://expedia.com/Pine-Island-Cabins.d553248635975874860-aaCabins.Travel-Guide-Accommodation)

## Frequently asked questions

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