Puxico Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Apr 3 - Apr 5
In two months
May 15 - May 17
In three months
Jun 12 - Jun 14
In four months
Jul 10 - Jul 12

Our top choices for Puxico vacation rentals

Front of property

Cabin in Williamsville

Lake Wappapello
2.0 star property
10.0 out of 10, Exceptional, (1 review)
"We did loose internet connection so gps did not always help but the local stores did. Also the managers answered their phones and were so helpful in many ways! I’m very glad we went."
United States
Dyann
$85 nightly
The price is $90
Apr 1 - Apr 2
Total with taxes and fees
Lake Wappapello
Living area

Apartment in Marble Hill

Charming 2-bedroom apartment in fabulous Marble Hill with AC
6.8 out of 10, (6 reviews)
"Host was not properly notified of the booking, but made the accommodations made several trips to make sure we were checked in and comfortable. Also gave very good advice for local points of interest."
United States
Chrystine H.
$127 nightly
The price is $136
Mar 20 - Mar 21
Total with taxes and fees
Charming 2-bedroom apartment in fabulous Marble Hill with AC
Pool

Vacation Home in Dexter

Dexter Homestead. Very Cozy & NEW Remodel !
7.8 out of 10, Good, (31 reviews)
"A weekin Dexter at this old, charming house. "
United States
Susan R.
$189 nightly
The price is $203
Mar 23 - Mar 24
Total with taxes and fees
Dexter Homestead. Very Cozy & NEW Remodel !
Fridge, microwave, oven, stovetop

Vacation Home in Williamsville

Hunting / Fishing Cabin at Lake Wappapello
$354 nightly
The price is $373
Mar 20 - Mar 21
Total with taxes and fees
Hunting / Fishing Cabin at Lake Wappapello
Property grounds

Camping in Clubb

Wanderers End Sanctuary Forest Farm & Village Co-op
$65 nightly
The price is $68
Mar 20 - Mar 21
Total with taxes and fees
Wanderers End Sanctuary Forest Farm & Village Co-op
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Puxico Hotel Reviews

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

8/10 Good
"Breakfast was delicious!"
Luis 1-night trip
Posted 1 hour ago
Hampton Inn Poplar Bluff

Find out more about Puxico

Everything you need to know about Puxico vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Puxico vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Puxico vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Puxico vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Puxico. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Puxico in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $90 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Puxico rentals

At Expedia, we put the best Puxico vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Puxico rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Puxico vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Puxico. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Puxico?

Yes, we offer vacation rentals close to popular sights in Puxico, or you can go with a more remote option if you're looking for a relaxing stay.

What's the top vacation rental that Puxico has to offer?

Private lake, beach & hot tub, romantic getaway or family vaca: This vacation home rental near Puxico is equipped with a hot tub, air-conditioning, and laundry facilities to help you feel comfortable during your stay.

What’s there to see and do in Puxico?

While exploring the area, visit family-friendly sights like Mo-Ark Regional Railroad Museum, or get outside and enjoy nature at Mark Twain National Forest. In the larger area, you’ll find Mingo Wilderness and Lake Wappapello.

What’s a vacation rental in Puxico like?

A vacation rental is a private property where you can stay for a couple of days or more in Puxico. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel right at home. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a family getaway.