Title: Top 10 Hotels in Santiago - Competitive Prices | Expedia.com [Vacation Rentals in Santiago](https://expedia.com/Santiago-Vacation-Rentals.d3000478258.Travel-Guide-VacationRentals)[Flights to Santiago](https://expedia.com/Cheap-Flights-To-Santiago.d3000478258.Travel-Guide-Flights)[Car Rentals in Santiago](https://expedia.com/Car-Rentals-In-Santiago.d3000478258.Car-Rental-Guide)[Santiago Vacation Packages](https://expedia.com/Santiago.d3000478258.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check prices for these dates Tonight [Apr 5 - Apr 6](https://www.expedia.com/Hotel-Search?regionId=3000478258&startDate=2026-04-05&endDate=2026-04-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 6 - Apr 7](https://www.expedia.com/Hotel-Search?regionId=3000478258&startDate=2026-04-06&endDate=2026-04-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=3000478258&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=3000478258&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantiago-Hotels.d3000478258.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantiago-Hotels.d3000478258.Travel-Guide-Hotels) ## Top Santiago Hotel Reviews ## Frequently asked questions ### If I need to cancel my hotel reservation in Santiago, will I receive a refund? ### Where can I learn more about changing or cancelling my trip to Santiago? ### What's the best hotel for staying near Libertador General Jose de San Martin Airport (PSS)? ### What's the weather like in Santiago? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [5 Star Hotels in Santa Rosa ](https://www.expedia.com/5Star-Santa-Rosa-Hotels.s50-0-d3000379166.Travel-Guide-Filter-Hotels) - [Ayolas Hotels ](https://www.expedia.com/Ayolas-Hotels.d3000472762.Travel-Guide-Hotels) - [5 Star Hotels in Ayolas ](https://www.expedia.com/5Star-Ayolas-Hotels.s50-0-d3000472762.Travel-Guide-Filter-Hotels) - [Misiones Department Hotels ](https://www.expedia.com/Destinations-In-Misiones-Department.d553248635975177264.Hotel-Destinations) - [Green Hotels in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-GreenSustainable.0-0-d553248635975177264-tGreenSustainable.Hotel-Filter-Destinations) - [Casino Hotels in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Casino-Hotel.0-0-d553248635975177264-tCasinoHotel.Hotel-Filter-Destinations) - [Resorts & Hotels with Spas in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Spa-Hotel.0-0-d553248635975177264-tSpaHotel.Hotel-Filter-Destinations) - [Hotels with Restaurants in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Hotels-With-Restaurants.0-0-d553248635975177264-tHotelswithRestaurants.Hotel-Filter-Destinations) - [Hotels with an Indoor Pool in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Hotels-With-Indoor-Pool.0-0-d553248635975177264-tHotelswithIndoorPool.Hotel-Filter-Destinations) - [Gay friendly Hotels in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-LGBT-Welcoming-Hotel.0-0-d553248635975177264-tLGBTWelcomingHotel.Hotel-Filter-Destinations) - [Waterpark Hotels in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Waterpark-Hotels.0-0-d553248635975177264-tWaterparkHotels.Hotel-Filter-Destinations) - [Cheap Hotels in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Cheap-Hotels.0-0-d553248635975177264-tCheapHotels.Hotel-Filter-Destinations) - [Hotels with a View in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Hotels-With-View.0-0-d553248635975177264-tHotelswithView.Hotel-Filter-Destinations) - [Rainforest & Jungle Hotels in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Jungle-Hotels.0-0-d553248635975177264-tJungleHotels.Hotel-Filter-Destinations) - [Beach Hotels in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Beach-Hotel.0-0-d553248635975177264-tBeachHotel.Hotel-Filter-Destinations) - [Boutique Hotels in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Boutique-Hotel.0-0-d553248635975177264-tBoutiqueHotel.Hotel-Filter-Destinations) - [Hotels with a Swim-up Bar in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Hotels-With-Swimup-Bar.0-0-d553248635975177264-tHotelswithSwimupBar.Hotel-Filter-Destinations) - [Hotels with Bars in Misiones Department ](https://www.expedia.com/Destinations-In-Misiones-Department-Bar-Hotel.0-0-d553248635975177264-tBarHotel.Hotel-Filter-Destinations) - [Santa Rosa Hotels ](https://www.expedia.com/Santa-Rosa-Hotels.d3000379166.Travel-Guide-Hotels) - [Flights to Ayolas ](https://www.expedia.com/Cheap-Flights-To-Ayolas.d3000472762.Travel-Guide-Flights) - [Flights to Santa Rosa ](https://www.expedia.com/Cheap-Flights-To-Santa-Rosa.d3000379166.Travel-Guide-Flights) - [Flights from Misiones Department ](https://www.expedia.com/lp/flights/553248635975177264/flights-from-misiones-department) - [Santa Rosa Vacations ](https://www.expedia.com/Santa-Rosa.d3000379166.Destination-Travel-Guides) - [Visit Ayolas ](https://www.expedia.com/Ayolas.dx3000472762) - [Ayolas Vacations ](https://www.expedia.com/Ayolas.d3000472762.Destination-Travel-Guides) - [Car rentals near Ayolas ](https://www.expedia.com/Car-Rentals-In-Ayolas.d3000472762.Car-Rental-Guide) - [Ayolas Vacation Rentals ](https://www.expedia.com/Ayolas-Vacation-Rentals.d3000472762.Travel-Guide-VacationRentals)