St. Charles Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals
  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings
  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for St. Charles vacation rentals

Vacation Home in Saint Charles

The Below Deck Suite
9.0 out of 10, Wonderful, (2 reviews)
"Overall good place for a family. The neighborhood is quiet and there is a good amount of space. Easy to find and to get places. You will hear the people upstairs and one bed was very squeaky. It was very clean and the couches are very comfy. "
United States
Amy B.
$229 nightly
The price is $229
Jan 21 - Jan 22
Total with taxes and fees
The Below Deck Suite
10.0 out of 10, Exceptional, (1 review)
"The place was beautiful and decorated well. Our experience was great and i recommend this rental. Would be nice if they honored military discount as I am a veteran. "
United States
Rodney M.
$219 nightly
The price is $219
Jan 21 - Jan 22
Total with taxes and fees
The Great Room - fully cozy & private Townhome

Apartment in Saint Charles

The Cul-de-Sac Retreat
8.4 out of 10, Very Good, (9 reviews)
"Great house, great location - close to the St. Charles convention center"
United States
Joe H.
$252 nightly
The price is $252
Jan 21 - Jan 22
Total with taxes and fees
The Cul-de-Sac Retreat

Apartment in St. Charles Historic District

6th street 101 - Walk to Main St
10.0 out of 10, Exceptional, (1 review)
$237 nightly
The price is $266
Jan 21 - Jan 22
Total with taxes and fees
6th street 101 - Walk to Main St

Vacation Home in Saint Charles

Casa de Saint Charles
9.2 out of 10, Wonderful, (17 reviews)
"We group of senior ladies thoroughly enjoyed our weekend at Casa de Saint Charles. The accommodations were perfect, inside and out. Our hosts were very accessible and made sure all our wants and needs were taken care of. What a wonderful home! "
United States
Rosalind W.
$319 nightly
The price is $319
Jan 21 - Jan 22
Total with taxes and fees
Casa de Saint Charles
8.8 out of 10, Excellent, (18 reviews)
"Wish we would have had more time to stay a little longer. Will definitely stay again in the future!"
United States
Rebecca O.
$241 nightly
The price is $265
Feb 1 - Feb 2
Total with taxes and fees
2 Bed Townhome w/ Backyard and Laundry by StayLage

Vacation Home in Saint Charles

Saint Charles White House
8.6 out of 10, Excellent, (4 reviews)
"It was great Needed towels but otherwise great"
United States
Jennifer R.
$333 nightly
The price is $333
Jan 21 - Jan 22
Total with taxes and fees
Saint Charles White House

Vacation Home in St. Charles Historic District

Historic 4‑BR Farmhouse • Steps to Main Street
10.0 out of 10, Exceptional, (22 reviews)
"The house was perfect for our stay. "
United States
Susan F.
$454 nightly
The price is $506
Jan 26 - Jan 27
Total with taxes and fees
Historic 4‑BR Farmhouse • Steps to Main Street

Vacation Home in Saint Charles

The Knotty Pine House
$252 nightly
The price is $252
Jan 21 - Jan 22
Total with taxes and fees
The Knotty Pine House

Vacation Home in St. Charles Historic District

5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
9.2 out of 10, Wonderful, (12 reviews)
"House was beautiful. Very nice quiet stay"
United States
Amy S.
$221 nightly
The price is $249
Jan 25 - Jan 26
Total with taxes and fees
5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
8.8 out of 10, Excellent, (9 reviews)
"Great place to stay for the weekend. Only 1 bathroom can be a stretch if you’re used to having access to multiple. However, it’s a quick walk to Upshot or Lady Di’s for coffee or breakfast. "
United States
Rachel Y.
$310 nightly
The price is $349
Jan 21 - Jan 22
Total with taxes and fees
The Olive House - Near Main Street- Fully rehabbed

Vacation Home in St. Charles Historic District

Madison House 1 -Walk to Main St
8.6 out of 10, Excellent, (17 reviews)
"The house was clean and well stocked, location was great, and plenty of street parking. "
United States
Brad K.
$206 nightly
The price is $232
Jan 21 - Jan 22
Total with taxes and fees
Madison House 1 -Walk to Main St

Vacation Home in Saint Charles

Spacious 2 bed Townhome by StayLage
9.0 out of 10, Wonderful, (9 reviews)
"Great location, clean, and management was informative and reacted to any needs quickly. Would recommend to anyone."
United States
Nathan D.
$251 nightly
The price is $276
Jan 21 - Jan 22
Total with taxes and fees
Spacious 2 bed Townhome by StayLage

Apartment in St. Charles Historic District

Duplex Hideaway in St. Charles, MO
10.0 out of 10, Exceptional, (5 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
$198 nightly
The price is $219
Jan 21 - Jan 22
Total with taxes and fees
Duplex Hideaway in St. Charles, MO

Vacation Home in St. Charles Historic District

Victorian Gem Steps from Main St - Sleeps 9 & Pets
9.8 out of 10, Exceptional, (22 reviews)
"A beautiful place with Victorian charm and modern amenities! This was the perfect place for our family."
United States
Kathleen D.
$513 nightly
The price is $572
Jan 28 - Jan 29
Total with taxes and fees
Victorian Gem Steps from Main St - Sleeps 9 & Pets

Vacation Home in St. Charles Historic District

St. Charles 1860's Gem - Sleeps 6!
9.8 out of 10, Exceptional, (136 reviews)
"Very comfortable house, beds are very comfy as well which is rare in a lot of VRBOs. Would definitely recommend! "
United States
Phillip R.
$239 nightly
The price is $239
Jan 23 - Jan 24
Total with taxes and fees
St. Charles 1860's Gem - Sleeps 6!

Vacation Home in Saint Charles

Spacious 2 Bedroom Townhome by StayLage
7.8 out of 10, Good, (12 reviews)
"Perfect size"
United States
Barbie D.
$253 nightly
The price is $278
Feb 8 - Feb 9
Total with taxes and fees
Spacious 2 Bedroom Townhome by StayLage

Apartment in St. Charles Historic District

Main Street Living! 2 Bedroom Unit right On Main!
9.6 out of 10, Exceptional, (34 reviews)
"Great Stay and great location! "
United States
Angela
$310 nightly
The price is $342
Jan 21 - Jan 22
Total with taxes and fees
Main Street Living! 2 Bedroom Unit right On Main!
9.8 out of 10, Exceptional, (17 reviews)
"It was very clean, beds were comfortable and the host was very accessible. It is also very convenient to downtown for and shops. "
United States
Kendra S.
$485 nightly
The price is $508
Jan 22 - Jan 23
Total with taxes and fees
3BR Historic St. Charles, MO-Walking distance to Main Street
8.8 out of 10, Excellent, (3 reviews)
"We loved the location for our travel needs and we had everything we needed for a family of two adults and two dogs. "
United States
Leslie R.
$494 nightly
The price is $589
Jan 21 - Jan 22
Total with taxes and fees
Winter SALE,Cozy 2BR Chalet, Hot Tub 1.2 Acres!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top St. Charles Hotel Reviews

Find out more about St. Charles

Everything you need to know about St. Charles vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Charles vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Charles in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $145 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Charles rentals

At Expedia, we put the best St. Charles vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, you can find vacation rentals near popular attractions in St. Charles, or you can choose a secluded option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in St. Charles. The live music and theater scene are some other things you might like to check out during your trip.

What are some of the best vacation rentals that St. Charles has to offer?

The St. Charles Guest House, lovely historic home, fun for families and groups: This St. Charles vacation home rental is located on a river and has a fireplace, a selection of games, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Some other top choices in St. Charles are 🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟 and St. Charles 1860's Gem - Sleeps 6!.

How many vacation rentals are there in St. Charles?

Expedia has 87 vacation rentals for your stay in St. Charles.

What can I see and do in St. Charles?

Katy Trail and Mississippi River are a couple of scenic spots to enjoy the outdoors, whereas Missouri Artists on Main is one of the cultural attractions. Other places in town to visit include Historic Main Street and First Missouri State Capitol Historic Site.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned accommodations you can book for several days or more in St. Charles. Vacation rentals provide amenities such as laundry facilities and kitchens to help you enjoy your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for a family getaway.