St. Charles Vacation Rentals from $100: Search Short-Term Rentals

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for St. Charles vacation rentals

St. Charles Manor | 4BR Getaway Home+HotTub+GameRm .6 acres

Saint Charles

Mary L.

$648 nightly

Jun 22 - Jun 23

Total with taxes and fees

Spacious 2 Bedroom Townhome

Saint Charles

Elizabeth

$285 nightly

Jun 21 - Jun 22

Total with taxes and fees

St. Charles Manor | 2BR Hot Tub Chalet | 1.2 Acres

Saint Charles

Leslie R.

$493 nightly

Jun 21 - Jun 22

Total with taxes and fees

Walk to St. Charles Entertainment

Saint Charles

Chloe

$294 nightly

Jun 28 - Jun 29

Total with taxes and fees

2 Bdr Upstairs Apt Walking Distance to Main St

Saint Charles

Tamas P.

$292 nightly

Jun 21 - Jun 22

Total with taxes and fees

Historic 5th Street House - Fully Rehabbed # 2

St. Charles Historic District

Steven S.

$227 nightly

Jun 22 - Jun 23

Total with taxes and fees

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

St. Charles Historic District

Ernest R.

$242 nightly

Jun 29 - Jun 30

Total with taxes and fees

6th street 101 - Walk to Main St

St. Charles Historic District

Scott N.

$252 nightly

Jun 21 - Jun 22

Total with taxes and fees

Cottage on Main st- Low Cleaning Fee

St. Charles Historic District

Debbie A.

$266 nightly

Jun 29 - Jun 30

Total with taxes and fees

Duplex Hideaway in St. Charles, MO

St. Charles Historic District

Karen M.

$247 nightly

Jun 29 - Jun 30

Total with taxes and fees

The Bourbon & Brass | Speakeasy-Inspired 2BDR

St. Charles Historic District

Marilyn

$298 nightly

Jun 21 - Jun 22

Total with taxes and fees

Historic 1908 Frenchtown Home

St. Charles Historic District

David M.

$330 nightly

Jun 25 - Jun 26

Total with taxes and fees

Charming open 4bd and screen-in porch! Sleeps 10!

Saint Charles

Dan R.

$479 nightly

Jun 21 - Jun 22

Total with taxes and fees

Stay on Main Historic Studio

St. Charles Historic District

Jacob G.

$207 nightly

Jun 30 - Jul 1

Total with taxes and fees

The Historic Bricks on Main

St. Charles Historic District

Michael C.

$243 nightly

Jun 30 - Jul 1

Total with taxes and fees

Cottage on Historic Main Street- Low Cleaning fee

St. Charles Historic District

Dora S.

$278 nightly

Jul 19 - Jul 20

Total with taxes and fees

The Lofts of North Main Street

St. Charles Historic District

jeramy p.

$243 nightly

Jun 29 - Jun 30

Total with taxes and fees

2 Bedroom Townhome Walking Distance to Streets

Saint Charles

William D.

$285 nightly

Jul 5 - Jul 6

Total with taxes and fees

HotTub-2br2b-near Historic Main Street

St. Charles Historic District

T M.

$322 nightly

Jul 7 - Jul 8

Total with taxes and fees

Amazing Renovated Historic Loft on Main Street

St. Charles Historic District

Emily B.

$258 nightly

Jun 21 - Jun 22

Total with taxes and fees

View all properties

Find vacation rentals that suit your style

Private vacation homes

Cabins

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Top St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"We had an excellent stay here! Check-in was easy and fast, the location is excellent for what we wanted to do in St. Louis, the staff was helpful, the hotel was clean, and we enjoyed the breakfast & 5:30 Kickback as well."

Hyatt Regency St. Louis at The Arch

10/10 Excellent

"Our room was perfect, clean, and well furnished. My teens used the workout facilities and enjoyed that. We were so close to the arch, it was an easy walk. Only issue we had at all was not the fault of the property, street racing was loud and went on until 4 am both nights we stayed, along with sirens, it was not easy to rest."

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"Hollywood is always a great hotel. Food pricing is pretty good too. They’ve updated the menu items at the restaurants. Ordered chicken tenders at “99” think they were $16 with fries. 5 huge tenders, saved them for later. Daiquiri’s and Dogs was good too. Chips and Cheese, they could do better but the Pink Lemonade Daiquiri was amazing. Only thing this time was called a couple of times and left the front desk messages for towels and none came also on a 5 day stay, housekeeping only came once. 4.9 stars though. First time this has happened"

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent

"The staff was so helpful, kind, friendly, and accommodating for any hotel, but a hotel in a big city was especially delightful. The staff went out of their way to help us. Even the custodian who was mopping the floors right outside the elevator on the floors with the garage was exceptionally friendly. The staff left a key for my husband, since he was flying in late that night and they let us keep our car parked in the garage even after we checked out so we could walk to The Arch. The workers were happy and laughing. I was so impressed. The room was very clean, the breakfast was very busy but the food was good and continued to be resupplied. The floors could have been confusing but signs in the elevator were so helpful."

Pear Tree Inn St. Louis Airport

8/10 Good

"The room was clean and staff was very friendly. The breakfast was better than expected (biscuits, gravy, eggs, sausage patties, muffin bagels, bread, cereal, homemade waffles, yougurt, fruit) The A/C worked very well, however the unit leaked onto the carpet in front of the window. We immediately informed the staff, who told us we couldn't be moved because the hotel was booked, but as guests checked out the next day we could have a different room. We were ok with that, since the ac worked fine. My family and I spent the next day sight-seeing. We checked with the front desk upon returning and were informed that maintenance had checked and the AC was not leaking anymore, they were unsure why it had leaked at all. They claim to have attempted to contact us to change rooms, but were unable to reach us. They had no other rooms available. "

Find out more about St. Charles

Everything you need to know about St. Charles vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Charles vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Charles in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $100 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Charles rentals

At Expedia, we put the best St. Charles vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Bridgeton Vacation Rentals

Things to do in Bridgeton

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, you can find vacation rentals near popular attractions in St. Charles, or you can choose a secluded option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in St. Charles. The live music and theater scene are some other things you might like to check out during your trip.

What are some of the best vacation rentals that St. Charles has to offer?

The St. Charles Guest House, lovely historic home, fun for families and groups: This St. Charles vacation home rental is located on a river and has a fireplace, a selection of games, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Some other top choices in St. Charles are 🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟 and St. Charles 1860's Gem - Sleeps 6!.

How many vacation rentals are there in St. Charles?

Expedia has 83 vacation rentals for your stay in St. Charles.

What can I see and do in St. Charles?

Katy Trail and Mississippi River are a couple of scenic spots to enjoy the outdoors, whereas Missouri Artists on Main is one of the cultural attractions. Other places in town to visit include Historic Main Street and Lewis & Clark Boathouse and Nature Center.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned accommodations you can book for several days or more in St. Charles. Vacation rentals provide amenities such as laundry facilities and kitchens to help you enjoy your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for a family getaway.

St. Charles Vacation Rentals

Bundle & Save

OneKeyCash

Upfront pricing

Check prices for these dates

Our top choices for St. Charles vacation rentals

St. Charles Manor | 4BR Getaway Home+HotTub+GameRm .6 acres

Spacious 2 Bedroom Townhome

St. Charles Manor | 2BR Hot Tub Chalet | 1.2 Acres

Walk to St. Charles Entertainment

2 Bdr Upstairs Apt Walking Distance to Main St

Historic 5th Street House - Fully Rehabbed # 2

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

6th street 101 - Walk to Main St

Cottage on Main st- Low Cleaning Fee

Duplex Hideaway in St. Charles, MO

The Bourbon & Brass | Speakeasy-Inspired 2BDR

Historic 1908 Frenchtown Home

Charming open 4bd and screen-in porch! Sleeps 10!

Stay on Main Historic Studio

The Historic Bricks on Main

Cottage on Historic Main Street- Low Cleaning fee

The Lofts of North Main Street

2 Bedroom Townhome Walking Distance to Streets

HotTub-2br2b-near Historic Main Street

Amazing Renovated Historic Loft on Main Street

Find vacation rentals that suit your style

Top St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Find out more about St. Charles

Explore a world of travel with Expedia

Frequently asked questions

Expedia's Latest Trends

Go further with the Expedia app