Title: Visit Worthington: 2026 Travel Guide for Worthington, Missouri | Expedia.com [Hotels in Worthington](https://expedia.com/Worthington-Hotels.d553248634983347772.Travel-Guide-Hotels)[Vacation Rentals in Worthington](https://expedia.com/Worthington-Vacation-Rentals.d553248634983347772.Travel-Guide-VacationRentals)[Car Rentals in Worthington](https://expedia.com/Car-Rentals-In-Worthington.d553248634983347772.Car-Rental-Guide)[Worthington Vacation Packages](https://expedia.com/Worthington.d553248634983347772.Destination-Travel-Guides) # Worthington, MO ## Travel Guide ## Visit Worthington ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_553248634983347772) - Worthington Hotel Deals - Vacation Rentals in Worthington ![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Kirksville 2604 N. Baltimore Street Kirksville MO $122 nightly $138 total Mar 8 - Mar 9 Total with taxes and fees Book a stay at this business-friendly hotel in Kirksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ... 9.2/10 Wonderful! (594 reviews) It was only a one night stay and everything was excellent ( registration, room, breakfast). Reviewed on Feb 22, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=19991846&PinnedHotelID=19991846&HadPinnedHotel=true®ionId=553248634983347772) ![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Super 8 by Wyndham Kirksville-University Area 1101 Country Club Dr Kirksville MO $60 nightly $67 total Feb 26 - Feb 27 Total with taxes and fees Book a stay at this golf hotel in Kirksville. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Thousand Hills State Park is located ... 9.2/10 Wonderful! (172 reviews) The hotel staff was very friendly and accommodating and even offered assistance with luggage. Check-in was fast. Staff even offered choice of rooms and provided pros and cons of each. Room was extremely clean, linens nice, and shower had great pressure. Hot breakfast of bacon, eggs, waffles along ... Reviewed on Feb 23, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F26%2F2026&endDate=2%2F27%2F2026&selected=123590&PinnedHotelID=123590&HadPinnedHotel=true®ionId=553248634983347772) ![Holiday Inn Express & Suites Kirksville - University Area by IHG](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express & Suites Kirksville - University Area by IHG 2523 South Franklin St. Kirksville MO $119 nightly $135 total Feb 27 - Feb 28 Total with taxes and fees Book a stay at this business-friendly hotel in Kirksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ... 9.2/10 Wonderful! (519 reviews) Hotel was broken for a day and a half. Reviewed on Feb 14, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F27%2F2026&endDate=2%2F28%2F2026&selected=18057874&PinnedHotelID=18057874&HadPinnedHotel=true®ionId=553248634983347772) [See all 47 properties in Worthington](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=2%2F25%2F2026&endDate=2%2F26%2F2026®ionId=553248634983347772) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Home in the Heart of Kirksville](https://images.trvl-media.com/lodging/104000000/103100000/103097400/103097370/1c70daa1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Home in the Heart of Kirksville Kirksville MO Stay at this vacation home in Kirksville. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attraction Thousand Hills State Park is located ... [](https://expedia.com/Kirksville-Hotels-Home-In-The-Heart-Of-Kirksville.h103097370.Hotel-Information) ![Country Cabin In The Woods](https://images.trvl-media.com/lodging/105000000/104310000/104308300/104308277/529c3996_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Country Cabin In The Woods Kirksville MO Stay at this cabin in Kirksville. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attraction Thousand Hills State Park is located ... 9.6/10 Exceptional! (13 reviews) The cabin never disappoints. Highly recommend. Hope to stay there again soon. Reviewed on Feb 8, 2026 [](https://expedia.com/Kirksville-Hotels-Country-Cabin-In-The-Woods.h104308277.Hotel-Information) ![Base Camp Cottage](https://images.trvl-media.com/lodging/112000000/111840000/111833600/111833563/aa1f0009_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Base Camp Cottage Kirksville MO Stay at this cottage in Kirksville. Enjoy laundry facilities and air conditioning. Popular attraction Thousand Hills State Park is located nearby. 10/10 Exceptional! (3 reviews) This house was perfect for my family to stay in. Our family was having a reunion in Thousand Hills State Park and this was just a short drive away. I SO appreciated that there were a few little toys for my kids to play with. The house had everything we needed and was very clean. Would definitely ... Reviewed on Jul 14, 2025 [](https://expedia.com/Kirksville-Hotels-Base-Camp-Cottage.h111833563.Hotel-Information) [See all properties in Worthington](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248634983347772&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Worthington hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983347772&startDate=2026-02-24&endDate=2026-02-25)[Feb 24 - Feb 25](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983347772&startDate=2026-02-24&endDate=2026-02-25) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983347772&startDate=2026-02-25&endDate=2026-02-26)[Feb 25 - Feb 26](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983347772&startDate=2026-02-25&endDate=2026-02-26) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983347772&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026)[Feb 27 - Mar 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983347772&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983347772&startDate=3%2F6%2F2026&endDate=3%2F8%2F2026)[Mar 6 - Mar 8](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983347772&startDate=3%2F6%2F2026&endDate=3%2F8%2F2026) ## Cities near Worthington ![spring sunrise over the Missouri River and Chariton River at Dalton Bottoms - aerial view](https://images.trvl-media.com/place/177595/22e7a5f7-b20c-41e0-adac-38dee5865f7a.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Unionville - Cities near Worthington - Places of interest [Unionville](https://expedia.com/Unionville.dx177595) - [Truman State University ](https://expedia.com/Truman-State-University-Kirksville.d553248621561636575.Vacation-Attraction) - [Lake Thunderhead ](https://expedia.com/Lake-Thunderhead-Unionville.d665709839042408448.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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