$229 Cheap Flights from Des Moines (DSM) to Milan (MXP)

View $229 flight on Wed, Jan 21, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Milan Malpensa Airport (MXP)

Cheap Flights from Des Moines to Milan (DSM-MXP)

Prices were available within the past 7 days and start at $229 for one-way flights and $500 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sun, Nov 16 - Thu, Dec 4
DSM
Des Moines
MXP
Milan
$500 Roundtrip, found 2 hours ago
$500
Roundtrip
found 2 hours ago
Select Delta flight, departing Sun, Nov 16 from Des Moines to Milan, returning Thu, Dec 4, priced at $500 found 2 hours ago
Air Canada
Wed, Mar 4 - Tue, Mar 17
DSM
Des Moines
MXP
Milan
$501 Roundtrip, found 2 hours ago
$501
Roundtrip
found 2 hours ago
Select Air Canada flight, departing Wed, Mar 4 from Des Moines to Milan, returning Tue, Mar 17, priced at $501 found 2 hours ago
Air Canada
Thu, Jan 15 - Wed, Jan 28
DSM
Des Moines
MXP
Milan
$502 Roundtrip, found 18 hours ago
$502
Roundtrip
found 18 hours ago
Select Air Canada flight, departing Thu, Jan 15 from Des Moines to Milan, returning Wed, Jan 28, priced at $502 found 18 hours ago
Air Canada
Thu, Jan 22 - Wed, Jan 28
DSM
Des Moines
MXP
Milan
$503 Roundtrip, found 20 hours ago
$503
Roundtrip
found 20 hours ago
Select Air Canada flight, departing Thu, Jan 22 from Des Moines to Milan, returning Wed, Jan 28, priced at $503 found 20 hours ago
Delta
Tue, Nov 18 - Thu, Dec 4
DSM
Des Moines
MXP
Milan
$503 Roundtrip, found 2 hours ago
$503
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Nov 18 from Des Moines to Milan, returning Thu, Dec 4, priced at $503 found 2 hours ago
American Airlines
Mon, Nov 17 - Wed, Dec 3
DSM
Des Moines
MXP
Milan
$504 Roundtrip, found 2 hours ago
$504
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Mon, Nov 17 from Des Moines to Milan, returning Wed, Dec 3, priced at $504 found 2 hours ago
Air Canada
Sun, Nov 9 - Tue, Nov 25
DSM
Des Moines
MXP
Milan
$506 Roundtrip, found 5 days ago
$506
Roundtrip
found 5 days ago
Select Air Canada flight, departing Sun, Nov 9 from Des Moines to Milan, returning Tue, Nov 25, priced at $506 found 5 days ago
Air Canada
Wed, Mar 4 - Tue, Mar 17
DSM
Des Moines
MXP
Milan
$507 Roundtrip, found 2 hours ago
$507
Roundtrip
found 2 hours ago
Select Air Canada flight, departing Wed, Mar 4 from Des Moines to Milan, returning Tue, Mar 17, priced at $507 found 2 hours ago
Lufthansa
Mon, Dec 1 - Tue, Dec 9
DSM
Des Moines
MXP
Milan
$509 Roundtrip, found 2 hours ago
$509
Roundtrip
found 2 hours ago
Select Lufthansa flight, departing Mon, Dec 1 from Des Moines to Milan, returning Tue, Dec 9, priced at $509 found 2 hours ago
British Airways
Sun, Nov 30 - Thu, Dec 11
DSM
Des Moines
MXP
Milan
$517 Roundtrip, found 20 hours ago
$517
Roundtrip
found 20 hours ago
Select British Airways flight, departing Sun, Nov 30 from Des Moines to Milan, returning Thu, Dec 11, priced at $517 found 20 hours ago

Alternative airports near Milan

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Linate LIN. Cheapest and Closest option available. Average driving time to city center is 11 minutes. Flights from $903
LIN
Linate
CheapestClosest
Average driving time to city center11 min
Flights from $903

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Malpensa Intl. Airport (MXP) cost?
Get a cheap one-way flight from $229 or cheap return flight from $500 from Des Moines Intl. Airport (DSM) to Malpensa Intl. Airport (MXP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Malpensa Intl. Airport (MXP)?
The cheapest month to fly from DSM to MXP is November, when there's less demand. Off-peak season is generally when better flight deals are available between these airports.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Malpensa Intl. Airport (MXP)?
To find the cheapest airline that'll fly you from DSM to MXP, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Des Moines Intl. Airport (DSM) to Malpensa Intl. Airport (MXP)?
You'll need to catch a flight with a layover when traveling from Des Moines Intl. Airport (DSM) to Malpensa Intl. Airport (MXP). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from DSM to MXP?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Malpensa Intl. Airport (MXP)?
Opt for a flight from Des Moines Intl. Airport (DSM) to Malpensa Intl. Airport (MXP) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Malpensa Intl. Airport (MXP) last-minute?
Booking your plane ticket from DSM to MXP right before your getaway is usually more expensive. However, if there's some wiggle room with your travel dates and times, you could grab a cheap last-minute fare.
Is it cheaper to book a DSM to MXP flight and hotel package?
Securing a DSM to MXP flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Choose from our impressive range of stays and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Malpensa Intl. Airport (MXP)?
It's generally possible to reschedule or cancel your DSM to MXP flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Malpensa Intl.
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, British Airways, Delta, Finnair, Iberia, KLM, Lufthansa, Scandinavian Airlines, United
Roundtrip price
$499
Distance
4752 mi

Book with confidence

Des Moines to Milan Flights

The cheapest times to fly from Des Moines to Milan

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Milan are during the month of November. You can find some of the cheapest flights from Des Moines to Milan with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Milan

Sunday is one of the best days to book for cheap flights from Des Moines to Milan: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Milan

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Milan in 2025. You can also book with separate airlines for your outbound and return journeys, from $229 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Milan flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Milan airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Milan Flights

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*Available to One Key members.